NO20004026D0 - Methods and intermediates useful for forming antifolates - Google Patents

Methods and intermediates useful for forming antifolates

Info

Publication number
NO20004026D0
NO20004026D0 NO20004026A NO20004026A NO20004026D0 NO 20004026 D0 NO20004026 D0 NO 20004026D0 NO 20004026 A NO20004026 A NO 20004026A NO 20004026 A NO20004026 A NO 20004026A NO 20004026 D0 NO20004026 D0 NO 20004026D0
Authority
NO
Norway
Prior art keywords
antifolates
methods
forming
intermediates useful
intermediates
Prior art date
Application number
NO20004026A
Other languages
Norwegian (no)
Other versions
NO20004026L (en
Inventor
Charles Jackson Barnett
Steven Eugene Dunlap
Michael Edward Kobierski
John Arnold Werner
Original Assignee
Lilly Co Eli
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lilly Co Eli filed Critical Lilly Co Eli
Publication of NO20004026D0 publication Critical patent/NO20004026D0/en
Publication of NO20004026L publication Critical patent/NO20004026L/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C255/00Carboxylic acid nitriles
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D471/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04Ortho-condensed systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D333/00Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/02Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
    • C07D333/04Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
    • C07D333/26Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D333/38Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02PCLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00Technologies relating to chemical industry
    • Y02P20/50Improvements relating to the production of bulk chemicals
    • Y02P20/55Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Treatments Of Macromolecular Shaped Articles (AREA)
  • Steroid Compounds (AREA)
  • Heterocyclic Compounds Containing Sulfur Atoms (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
  • Furan Compounds (AREA)
NO20004026A 1998-02-11 2000-08-10 Methods and intermediates useful for forming antifolates NO20004026L (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US7432798P 1998-02-11 1998-02-11
PCT/US1999/001689 WO1999041230A1 (en) 1998-02-11 1999-01-27 Processes and intermediates useful to make antifolates

Publications (2)

Publication Number Publication Date
NO20004026D0 true NO20004026D0 (en) 2000-08-10
NO20004026L NO20004026L (en) 2000-10-04

Family

ID=22118973

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20004026A NO20004026L (en) 1998-02-11 2000-08-10 Methods and intermediates useful for forming antifolates

Country Status (18)

Country Link
US (1) US6426417B1 (en)
EP (1) EP1054859A4 (en)
JP (1) JP2002503648A (en)
KR (1) KR20010040836A (en)
CN (1) CN1290247A (en)
AR (1) AR018538A1 (en)
AU (1) AU739292B2 (en)
BR (1) BR9907876A (en)
CA (1) CA2319424A1 (en)
EA (1) EA002723B1 (en)
HR (1) HRP20000537A2 (en)
HU (1) HUP0100869A3 (en)
IL (1) IL137685A0 (en)
NO (1) NO20004026L (en)
NZ (1) NZ505406A (en)
PL (1) PL342161A1 (en)
TR (1) TR200002352T2 (en)
WO (1) WO1999041230A1 (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2391153T3 (en) 2000-02-28 2012-11-22 Novartis Vaccines And Diagnostics S.R.L. Heterologous expression of Neisseria proteins
KR101686179B1 (en) 2015-02-05 2016-12-28 이삼구 An enhanced-containing arginine to nitric oxide generates a cricket

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS51113874A (en) 1975-04-01 1976-10-07 Yamanouchi Pharmaceut Co Ltd Method for synthesizing 4-hydroxynicotinic acid or its lower alkyl est ers
JPS55730A (en) 1978-06-20 1980-01-07 Toyo Soda Mfg Co Ltd 5-h-pyrido 1',2':1,2-pyrimido 4, 5-b acridine 7, 15-dione and its preparation
US4927828A (en) * 1985-03-08 1990-05-22 The Trustees Of Princeton University Diastereoisomeric tetrahydropyrido-(2,3,d) pyrimidine derivatives
NZ219971A (en) * 1986-06-06 1989-08-29 Univ Princeton Tetrahydropyrido (2,3-d pyrimidine derivatives and pharmaceutical compositions
US4895946A (en) * 1987-10-26 1990-01-23 The Trustees Of Princeton University Process for the preparation of fused pyridine compounds
DK172753B1 (en) * 1988-05-25 1999-06-28 Lilly Co Eli N- (5,6,7,8-tetrahydropyrido [2,3-d] pyrimidin-6-yl-alkanoyl) -glutamic acid derivatives, their use, pharmaceutical preparations
US5248775A (en) 1989-12-11 1993-09-28 The Trustees Of Princeton University Pyrrolo(2,3-d)pyrimidines
KR0162654B1 (en) 1989-12-11 1998-11-16 알렌 제이. 시니스갤리 N-[pyrrolo (2, 3-d) pyrimidin-3yl acryl]-glutamic acid derivatives
US5028608A (en) 1989-12-11 1991-07-02 The Trustees Of Princeton University N-(6-Amino-(pyrrolo(2,3-d)pyrimidin-3-ylacyl) )-glutamic acid derivatives
US5536724A (en) * 1992-03-03 1996-07-16 Sri International Antiinflammatory and antineoplastic 5-deazaaminopterins and 5,10-dideazaaminopterins

Also Published As

Publication number Publication date
HRP20000537A2 (en) 2000-10-31
TR200002352T2 (en) 2000-12-21
EA200000829A1 (en) 2001-02-26
EA002723B1 (en) 2002-08-29
AU739292B2 (en) 2001-10-11
WO1999041230A1 (en) 1999-08-19
NZ505406A (en) 2003-01-31
EP1054859A4 (en) 2003-03-05
CN1290247A (en) 2001-04-04
HUP0100869A2 (en) 2001-08-28
AU2345299A (en) 1999-08-30
EP1054859A1 (en) 2000-11-29
IL137685A0 (en) 2001-10-31
NO20004026L (en) 2000-10-04
PL342161A1 (en) 2001-05-21
HUP0100869A3 (en) 2002-12-28
KR20010040836A (en) 2001-05-15
AR018538A1 (en) 2001-11-28
JP2002503648A (en) 2002-02-05
BR9907876A (en) 2000-10-31
US6426417B1 (en) 2002-07-30
CA2319424A1 (en) 1999-08-19

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Legal Events

Date Code Title Description
FC2A Withdrawal, rejection or dismissal of laid open patent application