NO20003899L - FremgangsmÕter og mellomprodukter ved syntese av 5-(3-(ekso- bicyklo(2.2.1)hept-2-yloksy)-4-metoksyfenyl)-3,4,5,6- tetrahydropyrimdin-2(1H)-on - Google Patents

FremgangsmÕter og mellomprodukter ved syntese av 5-(3-(ekso- bicyklo(2.2.1)hept-2-yloksy)-4-metoksyfenyl)-3,4,5,6- tetrahydropyrimdin-2(1H)-on

Info

Publication number
NO20003899L
NO20003899L NO20003899A NO20003899A NO20003899L NO 20003899 L NO20003899 L NO 20003899L NO 20003899 A NO20003899 A NO 20003899A NO 20003899 A NO20003899 A NO 20003899A NO 20003899 L NO20003899 L NO 20003899L
Authority
NO
Norway
Prior art keywords
tetrahydropyrimdin
exobicyclo
hept
yloxy
methoxyphenyl
Prior art date
Application number
NO20003899A
Other languages
English (en)
Other versions
NO20003899D0 (no
NO311429B1 (no
Inventor
Thomas G Lacour
Charles W Murtiashaw
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Publication of NO20003899L publication Critical patent/NO20003899L/no
Application filed by Pfizer filed Critical Pfizer
Publication of NO20003899D0 publication Critical patent/NO20003899D0/no
Publication of NO311429B1 publication Critical patent/NO311429B1/no

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D239/00Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/06Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D239/08Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms directly attached in position 2
    • C07D239/10Oxygen or sulfur atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C235/00Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms
    • C07C235/02Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to acyclic carbon atoms and singly-bound oxygen atoms bound to the same carbon skeleton
    • C07C235/32Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to acyclic carbon atoms and singly-bound oxygen atoms bound to the same carbon skeleton the carbon skeleton containing six-membered aromatic rings
    • C07C235/34Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to acyclic carbon atoms and singly-bound oxygen atoms bound to the same carbon skeleton the carbon skeleton containing six-membered aromatic rings having the nitrogen atoms of the carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C255/00Carboxylic acid nitriles
    • C07C255/01Carboxylic acid nitriles having cyano groups bound to acyclic carbon atoms
    • C07C255/32Carboxylic acid nitriles having cyano groups bound to acyclic carbon atoms having cyano groups bound to acyclic carbon atoms of a carbon skeleton containing at least one six-membered aromatic ring
    • C07C255/37Carboxylic acid nitriles having cyano groups bound to acyclic carbon atoms having cyano groups bound to acyclic carbon atoms of a carbon skeleton containing at least one six-membered aromatic ring the carbon skeleton being further substituted by etherified hydroxy groups
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C259/00Compounds containing carboxyl groups, an oxygen atom of a carboxyl group being replaced by a nitrogen atom, this nitrogen atom being further bound to an oxygen atom and not being part of nitro or nitroso groups
    • C07C259/04Compounds containing carboxyl groups, an oxygen atom of a carboxyl group being replaced by a nitrogen atom, this nitrogen atom being further bound to an oxygen atom and not being part of nitro or nitroso groups without replacement of the other oxygen atom of the carboxyl group, e.g. hydroxamic acids
    • C07C259/06Compounds containing carboxyl groups, an oxygen atom of a carboxyl group being replaced by a nitrogen atom, this nitrogen atom being further bound to an oxygen atom and not being part of nitro or nitroso groups without replacement of the other oxygen atom of the carboxyl group, e.g. hydroxamic acids having carbon atoms of hydroxamic groups bound to hydrogen atoms or to acyclic carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C271/00Derivatives of carbamic acids, i.e. compounds containing any of the groups, the nitrogen atom not being part of nitro or nitroso groups
    • C07C271/06Esters of carbamic acids
    • C07C271/08Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms
    • C07C271/10Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms with the nitrogen atoms of the carbamate groups bound to hydrogen atoms or to acyclic carbon atoms
    • C07C271/16Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms with the nitrogen atoms of the carbamate groups bound to hydrogen atoms or to acyclic carbon atoms to carbon atoms of hydrocarbon radicals substituted by singly-bound oxygen atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C271/00Derivatives of carbamic acids, i.e. compounds containing any of the groups, the nitrogen atom not being part of nitro or nitroso groups
    • C07C271/06Esters of carbamic acids
    • C07C271/08Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms
    • C07C271/10Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms with the nitrogen atoms of the carbamate groups bound to hydrogen atoms or to acyclic carbon atoms
    • C07C271/20Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms with the nitrogen atoms of the carbamate groups bound to hydrogen atoms or to acyclic carbon atoms to carbon atoms of hydrocarbon radicals substituted by nitrogen atoms not being part of nitro or nitroso groups
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C69/00Esters of carboxylic acids; Esters of carbonic or haloformic acids
    • C07C69/66Esters of carboxylic acids having esterified carboxylic groups bound to acyclic carbon atoms and having any of the groups OH, O—metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety
    • C07C69/73Esters of carboxylic acids having esterified carboxylic groups bound to acyclic carbon atoms and having any of the groups OH, O—metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety of unsaturated acids
    • C07C69/734Ethers
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2603/00Systems containing at least three condensed rings
    • C07C2603/56Ring systems containing bridged rings
    • C07C2603/58Ring systems containing bridged rings containing three rings
    • C07C2603/70Ring systems containing bridged rings containing three rings containing only six-membered rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Liquid Crystal Substances (AREA)
  • Hydrogenated Pyridines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Cephalosporin Compounds (AREA)
NO20003899A 1994-08-05 2000-07-31 Fremgangsmåter for fremstilling av farmasöytisk aktive forbindelser NO311429B1 (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US28657994A 1994-08-05 1994-08-05
PCT/IB1995/000319 WO1996004253A1 (en) 1994-08-05 1995-05-04 Processes and intermediates in the synthesis of 5-(3-[exo-bicyclo[2.2.1]hept-2-yloxy]-4-methoxyphenyl)-3,4,5,6-tetrahydropyrimidin-2(1h)-one

Publications (3)

Publication Number Publication Date
NO20003899L true NO20003899L (no) 1997-04-02
NO20003899D0 NO20003899D0 (no) 2000-07-31
NO311429B1 NO311429B1 (no) 2001-11-26

Family

ID=23099248

Family Applications (3)

Application Number Title Priority Date Filing Date
NO970497A NO309471B1 (no) 1994-08-05 1997-02-04 Fremgangsmåter og mellomprodukter ved syntese av 5-(3-[ekso- bicyklo[2.2.1.]hept-2-yloksy]-4-metoksyfenyl)-3,4,5,6- tetrahydropyrimidin-2(1H)-on
NO20000404A NO310067B1 (no) 1994-08-05 2000-01-26 Fremgangsmåter for fremstilling av 5-(3-[ekso- bicyklo[2.2.1]hept-2-yloksy]-4-metoksyfenyl)-forbindelse og mellomprodukter
NO20003899A NO311429B1 (no) 1994-08-05 2000-07-31 Fremgangsmåter for fremstilling av farmasöytisk aktive forbindelser

Family Applications Before (2)

Application Number Title Priority Date Filing Date
NO970497A NO309471B1 (no) 1994-08-05 1997-02-04 Fremgangsmåter og mellomprodukter ved syntese av 5-(3-[ekso- bicyklo[2.2.1.]hept-2-yloksy]-4-metoksyfenyl)-3,4,5,6- tetrahydropyrimidin-2(1H)-on
NO20000404A NO310067B1 (no) 1994-08-05 2000-01-26 Fremgangsmåter for fremstilling av 5-(3-[ekso- bicyklo[2.2.1]hept-2-yloksy]-4-metoksyfenyl)-forbindelse og mellomprodukter

Country Status (16)

Country Link
US (3) US6022968A (no)
EP (1) EP0775119A1 (no)
JP (1) JP2960965B2 (no)
KR (1) KR100234602B1 (no)
CN (2) CN1431194A (no)
AU (1) AU704116B2 (no)
CA (1) CA2196309C (no)
FI (1) FI970470A0 (no)
IL (1) IL114757A0 (no)
MX (1) MX9700960A (no)
MY (1) MY114675A (no)
NO (3) NO309471B1 (no)
NZ (1) NZ284144A (no)
TW (1) TW427981B (no)
WO (1) WO1996004253A1 (no)
ZA (1) ZA956539B (no)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6994612B2 (en) * 2002-02-13 2006-02-07 Micron Technology, Inc. Methods for conditioning surfaces of polishing pads after chemical-mechanical polishing

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HU215433B (hu) * 1986-04-29 2000-05-28 Pfizer Inc. Eljárás új 2-oxo-5-fenil-pirimidin-származékok előállítására
US5270206A (en) * 1989-11-13 1993-12-14 Pfizer Inc. Enzymatic resolution of endo-bicyclo[2.2.1]heptan-2-ol and derived pharmaceutical agents
JP3100984B2 (ja) * 1992-12-02 2000-10-23 ファイザー・インク. 選択的pde▲下i▼▲下v▼阻害物質としてのカテコールジエーテル類

Also Published As

Publication number Publication date
JP2960965B2 (ja) 1999-10-12
NO20003899D0 (no) 2000-07-31
NO311429B1 (no) 2001-11-26
MY114675A (en) 2002-12-31
IL114757A0 (en) 1995-11-27
CN1431195A (zh) 2003-07-23
AU704116B2 (en) 1999-04-15
US20010041798A1 (en) 2001-11-15
NZ284144A (en) 1999-02-25
TW427981B (en) 2001-04-01
ZA956539B (en) 1997-02-04
NO20000404L (no) 1997-04-02
NO970497L (no) 1997-04-02
US6274733B1 (en) 2001-08-14
KR100234602B1 (ko) 1999-12-15
CA2196309A1 (en) 1996-02-15
KR970704700A (ko) 1997-09-06
NO310067B1 (no) 2001-05-14
US6022968A (en) 2000-02-08
CN1431194A (zh) 2003-07-23
FI970470A (fi) 1997-02-04
NO20000404D0 (no) 2000-01-26
WO1996004253A1 (en) 1996-02-15
FI970470A0 (fi) 1997-02-04
NO309471B1 (no) 2001-02-05
NO970497D0 (no) 1997-02-04
JPH09508643A (ja) 1997-09-02
EP0775119A1 (en) 1997-05-28
CA2196309C (en) 2001-10-16
MX9700960A (es) 1997-05-31
US6399776B2 (en) 2002-06-04
AU2265595A (en) 1996-03-04

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