NO154751C - ANALOGUE PROCEDURE FOR THE PREPARATION OF THERAPEUTICALLY EFFECTIVE HYDROXYCARBONYL PHOSPHONIC ACID ESTERS. - Google Patents
ANALOGUE PROCEDURE FOR THE PREPARATION OF THERAPEUTICALLY EFFECTIVE HYDROXYCARBONYL PHOSPHONIC ACID ESTERS.Info
- Publication number
- NO154751C NO154751C NO784330A NO784330A NO154751C NO 154751 C NO154751 C NO 154751C NO 784330 A NO784330 A NO 784330A NO 784330 A NO784330 A NO 784330A NO 154751 C NO154751 C NO 154751C
- Authority
- NO
- Norway
- Prior art keywords
- hydroxycarbonyl
- preparation
- therapeutically effective
- acid esters
- phosphonic acid
- Prior art date
Links
- ZJAOAACCNHFJAH-UHFFFAOYSA-N phosphonoformic acid Chemical class OC(=O)P(O)(O)=O ZJAOAACCNHFJAH-UHFFFAOYSA-N 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/28—Phosphorus compounds with one or more P—C bonds
- C07F9/38—Phosphonic acids [RP(=O)(OH)2]; Thiophosphonic acids ; [RP(=X1)(X2H)2(X1, X2 are each independently O, S or Se)]
- C07F9/3804—Phosphonic acids [RP(=O)(OH)2]; Thiophosphonic acids ; [RP(=X1)(X2H)2(X1, X2 are each independently O, S or Se)] not used, see subgroups
- C07F9/3886—Acids containing the structure -C(=X)-P(=X)(XH)2 or NC-P(=X)(XH)2, (X = O, S, Se)
- C07F9/3891—Acids containing the structure -C(=X)-P(=X)(XH)2, (X = O, S, Se)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/16—Antivirals for RNA viruses for influenza or rhinoviruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/28—Phosphorus compounds with one or more P—C bonds
- C07F9/38—Phosphonic acids [RP(=O)(OH)2]; Thiophosphonic acids ; [RP(=X1)(X2H)2(X1, X2 are each independently O, S or Se)]
- C07F9/40—Esters thereof
- C07F9/4003—Esters thereof the acid moiety containing a substituent or a structure which is considered as characteristic
- C07F9/4062—Esters of acids containing the structure -C(=X)-P(=X)(XR)2 or NC-P(=X)(XR)2, (X = O, S, Se)
- C07F9/4065—Esters of acids containing the structure -C(=X)-P(=X)(XR)2, (X = O, S, Se)
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Crystallography & Structural Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Virology (AREA)
- Pharmacology & Pharmacy (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Pulmonology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (8)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB5358377 | 1977-12-22 | ||
GB5358177 | 1977-12-22 | ||
GB5358277 | 1977-12-22 | ||
GB5358077 | 1977-12-22 | ||
GB7828548 | 1978-07-03 | ||
GB7828552 | 1978-07-03 | ||
GB7828553 | 1978-07-03 | ||
GB7828555 | 1978-07-03 |
Publications (3)
Publication Number | Publication Date |
---|---|
NO784330L NO784330L (en) | 1979-06-25 |
NO154751B NO154751B (en) | 1986-09-08 |
NO154751C true NO154751C (en) | 1986-12-17 |
Family
ID=27571200
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
NO784331A NO156611C (en) | 1977-12-22 | 1978-12-21 | ANALOGY PROCEDURE FOR THE PREPARATION OF THERAPEUTIC EFFECTIVE DERIVATIVES OF HYDROXYCARBONYLPHOSPHONIC ACID. |
NO784330A NO154751C (en) | 1977-12-22 | 1978-12-21 | ANALOGUE PROCEDURE FOR THE PREPARATION OF THERAPEUTICALLY EFFECTIVE HYDROXYCARBONYL PHOSPHONIC ACID ESTERS. |
Family Applications Before (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
NO784331A NO156611C (en) | 1977-12-22 | 1978-12-21 | ANALOGY PROCEDURE FOR THE PREPARATION OF THERAPEUTIC EFFECTIVE DERIVATIVES OF HYDROXYCARBONYLPHOSPHONIC ACID. |
Country Status (14)
Country | Link |
---|---|
US (4) | US4372894A (en) |
EP (2) | EP0003275B1 (en) |
JP (2) | JPS54109951A (en) |
AT (1) | AT369017B (en) |
AU (1) | AU530031B2 (en) |
CA (2) | CA1140049A (en) |
DE (2) | DE2861729D1 (en) |
DK (2) | DK148631C (en) |
FI (2) | FI65438C (en) |
HK (1) | HK33584A (en) |
IE (1) | IE48011B1 (en) |
MY (1) | MY8500058A (en) |
NO (2) | NO156611C (en) |
SG (1) | SG82383G (en) |
Families Citing this family (40)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CA1140049A (en) * | 1977-12-22 | 1983-01-25 | Dke J.E. Helgstran | Pharmaceutical preparations from derivatives of hydroxycarbonylphosphonic acid |
GB8501374D0 (en) * | 1985-01-18 | 1985-02-20 | Wellcome Found | Treatment of aids |
US4806532A (en) * | 1985-10-08 | 1989-02-21 | Mayo Foundation For Medical Education And Research | Inhibition of epithelial phosphate transport |
US6492352B1 (en) * | 1985-10-31 | 2002-12-10 | Astra Lakemedel Aktiebolag | Method for the control and treatment of acquired immunodeficiency syndrome (AIDS) |
US5166386A (en) * | 1989-09-18 | 1992-11-24 | E. R. Squibb & Sons, Inc. | Process of making isoprenoid phosphinylformic acid squalene synthetase inhibitors |
US5025003A (en) * | 1989-09-18 | 1991-06-18 | E. R. Squibb & Sons, Inc. | Isoprenoid phosphinylformic acid squalene synthetase inhibitors |
US5463092A (en) * | 1989-11-22 | 1995-10-31 | Vestar, Inc. | Lipid derivatives of phosphonacids for liposomal incorporation and method of use |
US5132414A (en) * | 1990-05-10 | 1992-07-21 | Dana-Farber Cancer Institute, Inc. | Dideoxynucleoside-5'-phosphonoformic acid compounds |
US5696277A (en) * | 1994-11-15 | 1997-12-09 | Karl Y. Hostetler | Antiviral prodrugs |
US7517858B1 (en) | 1995-06-07 | 2009-04-14 | The Regents Of The University Of California | Prodrugs of pharmaceuticals with improved bioavailability |
US6096730A (en) * | 1997-07-24 | 2000-08-01 | University Of Kentucky Research Foundation | Phosphonated agents and their antiangiogenic and antitumorigenic use |
US5869469A (en) * | 1997-08-18 | 1999-02-09 | Queen's University At Kingston | Phosphonocarboxylate compounds for treating amyloidosis |
CA2300910C (en) * | 1997-08-18 | 2008-02-26 | Queen's University At Kingston | Phosphono-carboxylate compounds for treating amyloidosis |
DK1054664T3 (en) * | 1998-02-11 | 2012-11-05 | Bhi Ltd Partnership | Method for modulating macrophage activation |
US20040002079A1 (en) * | 1998-02-11 | 2004-01-01 | Gunn Robert B. | Sodium-phosphate cotransporter in lithium therapy for the treatment of mental illness |
US20020022657A1 (en) * | 1998-02-11 | 2002-02-21 | Francine Gervais | Methods for modulating neuronal cell death |
US6329356B1 (en) * | 1998-04-10 | 2001-12-11 | Neurochem, Inc. | Phosphono-carboxylate compounds for treating amyloidosis |
US6310073B1 (en) * | 1998-07-28 | 2001-10-30 | Queen's University At Kingston | Methods and compositions to treat glycosaminoglycan-associated molecular interactions |
CA2369997C (en) * | 1999-04-28 | 2009-11-17 | Queen's University At Kingston | Compositions and methods for treating amyloidosis |
US6562836B1 (en) | 1999-05-24 | 2003-05-13 | Queen's University Of Kingston | Methods and compounds for inhibiting amyloid deposits |
EP1251837A2 (en) | 1999-12-23 | 2002-10-30 | Neurochem, Inc. | Compounds and methods for modulating cerebral amyloid angiopathy |
MXPA04009672A (en) * | 2002-04-01 | 2004-11-12 | Pfizer | Pyranon and pyrandion inhibitors of hepatitis c virus rna-dependent rna polymerase. |
DOP2003000641A (en) * | 2002-05-10 | 2003-11-15 | Pfizer | INHIBITORS OF RNA-DEPENDENT RNA POLYMERASE OF HEPATITIS C VIRUSES AND COMPOSITIONS AND TREATMENT USED |
US7148226B2 (en) * | 2003-02-21 | 2006-12-12 | Agouron Pharmaceuticals, Inc. | Inhibitors of hepatitis C virus RNA-dependent RNA polymerase, and compositions and treatments using the same |
US20040214178A1 (en) * | 2003-04-24 | 2004-10-28 | Agouron Pharmaceuticals, Inc. | Reporter-selectable Hepatitis C virus replicon |
US20070010573A1 (en) * | 2003-06-23 | 2007-01-11 | Xianqi Kong | Methods and compositions for treating amyloid-related diseases |
US7244764B2 (en) * | 2003-06-23 | 2007-07-17 | Neurochem (International) Limited | Methods and compositions for treating amyloid-related diseases |
US7414076B2 (en) | 2003-06-23 | 2008-08-19 | Neurochem (International) Limited | Methods and compositions for treating amyloid-related diseases |
GEP20094751B (en) * | 2004-08-18 | 2009-08-10 | Pfizer | Inhibitors of hepatitis c virus rna-dependent rna polymerase, and compositions and treatments using the same |
ITMI20041822A1 (en) * | 2004-09-24 | 2004-12-24 | Pharmaproducts Uk Ltd | "USEFUL THERAPEUTIC AGENT FOR THE TREATMENT OF PLASMACELLULAR NEOPLASIES" |
US20060167057A1 (en) * | 2004-11-16 | 2006-07-27 | Xianqi Kong | Compounds for the treatment of CNS and amyloid associated diseases |
US8044100B2 (en) | 2004-12-22 | 2011-10-25 | Bellus Health Inc. | Methods and compositions for treating amyloid-related diseases |
MX2008008213A (en) * | 2005-12-22 | 2008-09-03 | Neurochem Int Ltd | Treatment of renal disorders, diabetic nephopathy and dyslipidemias. |
DK2089417T3 (en) | 2006-10-12 | 2015-03-23 | Bhi Ltd Partnership | Methods, Compounds, Compositions and Vehicles for Delivery of 3-Amion-1-Propanesulfonic Acid |
MX2009006768A (en) * | 2006-12-22 | 2009-08-31 | Bellus Health Int Ltd | Methods, compounds, and compositions for treating metabolic disorders and diabetes. |
US20080293648A1 (en) * | 2007-01-05 | 2008-11-27 | Saha Pharmaceuticals, Inc. | Compositions and Methods for Cancer Treatment |
DE102012103717A1 (en) * | 2012-04-27 | 2013-11-14 | Westfälische Wilhelms-Universität Münster | Use of phosphonoformic acid or its hydrate, ester and/or salt for treating tumor diseases and/or age-related macular degeneration, where tumor diseases are fibroblast growth factor-2 overexpressing tumors consisting of e.g. melanoma |
CN105830271B (en) * | 2013-12-19 | 2018-11-16 | 宇部兴产株式会社 | Nonaqueous electrolytic solution, used its electrical storage device and its used in phosphonoformic acid compound |
ES2578902B1 (en) * | 2014-12-29 | 2017-07-07 | Agencia Pública Empresarial Sanitaria Costa Del Sol | Use of pyrophosphate ion analogs for the treatment of HPV infection |
CN109400645A (en) * | 2017-08-18 | 2019-03-01 | 四川海思科制药有限公司 | A kind of phosphoric acid derivatives and preparation method and purposes |
Family Cites Families (16)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3155597A (en) * | 1961-06-23 | 1964-11-03 | Monsanto Co | Extractive separation process |
US3997544A (en) * | 1968-05-24 | 1976-12-14 | E. I. Du Pont De Nemours And Company | Plant growth regulant carbamoylphosphonates |
US3846512A (en) * | 1968-05-24 | 1974-11-05 | Du Pont | Carbamoylphosphonates |
CH513590A (en) | 1968-05-24 | 1971-10-15 | Du Pont | Plant growth regulator containing carbamoyl phosphonate |
US3533995A (en) * | 1968-08-27 | 1970-10-13 | Fmc Corp | Heat stabilization of polyester resin with alkyl dialkoxyphosphinyl formate |
US3849102A (en) * | 1969-08-14 | 1974-11-19 | Du Pont | Plant growth regulant method |
GB1317768A (en) | 1969-08-14 | 1973-05-23 | Du Pont | Plant growth regulants |
US3767795A (en) * | 1971-02-25 | 1973-10-23 | Abbott Lab | Method for combating certain virus infection |
US3943201A (en) * | 1973-07-23 | 1976-03-09 | E. I. Du Pont De Nemours And Comapny | Alkoxy carboxycarbonylphosphonic acid esters |
HU171255B (en) | 1973-07-23 | 1977-12-28 | Du Pont | Compositions for controling plant-growing |
US4017297A (en) * | 1975-08-29 | 1977-04-12 | E. I. Du Pont De Nemours And Company | Phosphonates for the control of bindweed |
US4092412A (en) * | 1976-04-30 | 1978-05-30 | Abbott Laboratories | Treatment of herpes simplex infections |
US4052439A (en) * | 1976-04-30 | 1977-10-04 | Abbott Laboratories | Carboxylic esters of phosphonoacetic acid |
CA1069526A (en) * | 1976-04-30 | 1980-01-08 | Thomas R. Herrin | Phosphorus esters of phosphonoacetic acid |
SE7607496L (en) * | 1976-07-01 | 1978-01-02 | Astra Laekemedel Ab | METHOD FOR FIGHTING VIRUS INFECTIONS |
CA1140049A (en) * | 1977-12-22 | 1983-01-25 | Dke J.E. Helgstran | Pharmaceutical preparations from derivatives of hydroxycarbonylphosphonic acid |
-
1978
- 1978-12-06 CA CA000317487A patent/CA1140049A/en not_active Expired
- 1978-12-06 CA CA000317520A patent/CA1144937A/en not_active Expired
- 1978-12-15 DK DK564178A patent/DK148631C/en not_active IP Right Cessation
- 1978-12-15 DK DK564278A patent/DK148632C/en not_active IP Right Cessation
- 1978-12-18 IE IE2493/78A patent/IE48011B1/en not_active IP Right Cessation
- 1978-12-19 AU AU42682/78A patent/AU530031B2/en not_active Expired
- 1978-12-19 EP EP78850027A patent/EP0003275B1/en not_active Expired
- 1978-12-19 DE DE7878850028T patent/DE2861729D1/en not_active Expired
- 1978-12-19 DE DE7878850027T patent/DE2861045D1/en not_active Expired
- 1978-12-19 EP EP78850028A patent/EP0003007B1/en not_active Expired
- 1978-12-20 FI FI783931A patent/FI65438C/en not_active IP Right Cessation
- 1978-12-20 FI FI783932A patent/FI68626C/en not_active IP Right Cessation
- 1978-12-21 NO NO784331A patent/NO156611C/en unknown
- 1978-12-21 NO NO784330A patent/NO154751C/en unknown
- 1978-12-22 JP JP15839878A patent/JPS54109951A/en active Granted
- 1978-12-22 JP JP15839978A patent/JPS54106431A/en active Granted
- 1978-12-22 AT AT0921778A patent/AT369017B/en not_active IP Right Cessation
-
1979
- 1979-11-13 US US06/093,166 patent/US4372894A/en not_active Expired - Lifetime
- 1979-11-13 US US06/093,167 patent/US4386081A/en not_active Expired - Lifetime
-
1982
- 1982-09-10 US US06/416,632 patent/US4536400A/en not_active Expired - Lifetime
- 1982-12-17 US US06/450,656 patent/US4591583A/en not_active Expired - Fee Related
-
1983
- 1983-12-23 SG SG823/83A patent/SG82383G/en unknown
-
1984
- 1984-04-18 HK HK335/84A patent/HK33584A/en not_active IP Right Cessation
-
1985
- 1985-12-30 MY MY58/85A patent/MY8500058A/en unknown
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