NO146697B - Aqueous storage-stable concentrates of microbicides by way of oxidizing mixtures based on percarboxylic acids and hydrogen peroxide - Google Patents
Aqueous storage-stable concentrates of microbicides by way of oxidizing mixtures based on percarboxylic acids and hydrogen peroxide Download PDFInfo
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- NO146697B NO146697B NO762605A NO762605A NO146697B NO 146697 B NO146697 B NO 146697B NO 762605 A NO762605 A NO 762605A NO 762605 A NO762605 A NO 762605A NO 146697 B NO146697 B NO 146697B
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- 239000012141 concentrate Substances 0.000 title claims description 36
- 239000000203 mixture Substances 0.000 title claims description 14
- 239000002253 acid Substances 0.000 title claims description 11
- 230000003641 microbiacidal effect Effects 0.000 title claims description 10
- 229940124561 microbicide Drugs 0.000 title claims description 7
- 230000001590 oxidative effect Effects 0.000 title claims description 5
- 150000007513 acids Chemical class 0.000 title claims description 4
- MHAJPDPJQMAIIY-UHFFFAOYSA-N Hydrogen peroxide Chemical compound OO MHAJPDPJQMAIIY-UHFFFAOYSA-N 0.000 title description 6
- QTBSBXVTEAMEQO-UHFFFAOYSA-N Acetic acid Chemical compound CC(O)=O QTBSBXVTEAMEQO-UHFFFAOYSA-N 0.000 claims description 42
- KFSLWBXXFJQRDL-UHFFFAOYSA-N Peracetic acid Chemical compound CC(=O)OO KFSLWBXXFJQRDL-UHFFFAOYSA-N 0.000 claims description 30
- -1 aliphatic monocarboxylic acids Chemical class 0.000 claims description 11
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 11
- ABLZXFCXXLZCGV-UHFFFAOYSA-N Phosphorous acid Chemical compound OP(O)=O ABLZXFCXXLZCGV-UHFFFAOYSA-N 0.000 claims description 8
- 239000002855 microbicide agent Substances 0.000 claims description 8
- 239000000080 wetting agent Substances 0.000 claims description 8
- 125000004432 carbon atom Chemical group C* 0.000 claims description 7
- 150000004965 peroxy acids Chemical class 0.000 claims description 6
- 150000003839 salts Chemical class 0.000 claims description 5
- DBVJJBKOTRCVKF-UHFFFAOYSA-N Etidronic acid Chemical compound OP(=O)(O)C(O)(C)P(O)(O)=O DBVJJBKOTRCVKF-UHFFFAOYSA-N 0.000 claims description 4
- YDONNITUKPKTIG-UHFFFAOYSA-N [Nitrilotris(methylene)]trisphosphonic acid Chemical compound OP(O)(=O)CN(CP(O)(O)=O)CP(O)(O)=O YDONNITUKPKTIG-UHFFFAOYSA-N 0.000 claims description 4
- 230000002378 acidificating effect Effects 0.000 claims description 4
- IDYCJOKDHJLCGO-UHFFFAOYSA-N (amino-phenyl-phosphonomethyl)phosphonic acid Chemical compound OP(=O)(O)C(P(O)(O)=O)(N)C1=CC=CC=C1 IDYCJOKDHJLCGO-UHFFFAOYSA-N 0.000 claims description 3
- 125000001931 aliphatic group Chemical group 0.000 claims description 3
- 125000000129 anionic group Chemical group 0.000 claims description 3
- 229910021653 sulphate ion Inorganic materials 0.000 claims description 2
- 239000003795 chemical substances by application Substances 0.000 description 6
- 150000003009 phosphonic acids Chemical class 0.000 description 6
- NBIIXXVUZAFLBC-UHFFFAOYSA-N Phosphoric acid Chemical compound OP(O)(O)=O NBIIXXVUZAFLBC-UHFFFAOYSA-N 0.000 description 4
- 238000004519 manufacturing process Methods 0.000 description 4
- 238000004659 sterilization and disinfection Methods 0.000 description 4
- 239000000725 suspension Substances 0.000 description 4
- 230000000694 effects Effects 0.000 description 3
- 229940120146 EDTMP Drugs 0.000 description 2
- 241000191967 Staphylococcus aureus Species 0.000 description 2
- BFDMEODWJJUORJ-UHFFFAOYSA-N [dimethylamino(phosphono)methyl]phosphonic acid Chemical compound CN(C)C(P(O)(O)=O)P(O)(O)=O BFDMEODWJJUORJ-UHFFFAOYSA-N 0.000 description 2
- 125000000217 alkyl group Chemical group 0.000 description 2
- 150000008051 alkyl sulfates Chemical class 0.000 description 2
- 150000008052 alkyl sulfonates Chemical class 0.000 description 2
- 229910000147 aluminium phosphate Inorganic materials 0.000 description 2
- 239000003443 antiviral agent Substances 0.000 description 2
- 150000001875 compounds Chemical class 0.000 description 2
- XBDQKXXYIPTUBI-UHFFFAOYSA-N dimethylselenoniopropionate Natural products CCC(O)=O XBDQKXXYIPTUBI-UHFFFAOYSA-N 0.000 description 2
- NFDRPXJGHKJRLJ-UHFFFAOYSA-N edtmp Chemical compound OP(O)(=O)CN(CP(O)(O)=O)CCN(CP(O)(O)=O)CP(O)(O)=O NFDRPXJGHKJRLJ-UHFFFAOYSA-N 0.000 description 2
- 230000008029 eradication Effects 0.000 description 2
- 239000011368 organic material Substances 0.000 description 2
- 230000003647 oxidation Effects 0.000 description 2
- 238000007254 oxidation reaction Methods 0.000 description 2
- 239000010902 straw Substances 0.000 description 2
- 239000004753 textile Substances 0.000 description 2
- KMDMOMDSEVTJTI-UHFFFAOYSA-N 2-phosphonobutanedioic acid Chemical compound OC(=O)CC(C(O)=O)P(O)(O)=O KMDMOMDSEVTJTI-UHFFFAOYSA-N 0.000 description 1
- QGZKDVFQNNGYKY-UHFFFAOYSA-O Ammonium Chemical compound [NH4+] QGZKDVFQNNGYKY-UHFFFAOYSA-O 0.000 description 1
- MPXCBQCUNKTGGN-UHFFFAOYSA-N CN(C)C.OP(=O)OP(O)=O Chemical compound CN(C)C.OP(=O)OP(O)=O MPXCBQCUNKTGGN-UHFFFAOYSA-N 0.000 description 1
- OYPRJOBELJOOCE-UHFFFAOYSA-N Calcium Chemical compound [Ca] OYPRJOBELJOOCE-UHFFFAOYSA-N 0.000 description 1
- DGAQECJNVWCQMB-PUAWFVPOSA-M Ilexoside XXIX Chemical compound C[C@@H]1CC[C@@]2(CC[C@@]3(C(=CC[C@H]4[C@]3(CC[C@@H]5[C@@]4(CC[C@@H](C5(C)C)OS(=O)(=O)[O-])C)C)[C@@H]2[C@]1(C)O)C)C(=O)O[C@H]6[C@@H]([C@H]([C@@H]([C@H](O6)CO)O)O)O.[Na+] DGAQECJNVWCQMB-PUAWFVPOSA-M 0.000 description 1
- ZLMJMSJWJFRBEC-UHFFFAOYSA-N Potassium Chemical compound [K] ZLMJMSJWJFRBEC-UHFFFAOYSA-N 0.000 description 1
- YSMRWXYRXBRSND-UHFFFAOYSA-N TOTP Chemical compound CC1=CC=CC=C1OP(=O)(OC=1C(=CC=CC=1)C)OC1=CC=CC=C1C YSMRWXYRXBRSND-UHFFFAOYSA-N 0.000 description 1
- CIUQDSCDWFSTQR-UHFFFAOYSA-N [C]1=CC=CC=C1 Chemical compound [C]1=CC=CC=C1 CIUQDSCDWFSTQR-UHFFFAOYSA-N 0.000 description 1
- 125000000218 acetic acid group Chemical group C(C)(=O)* 0.000 description 1
- 150000008043 acidic salts Chemical class 0.000 description 1
- 239000000654 additive Substances 0.000 description 1
- 229940045714 alkyl sulfonate alkylating agent Drugs 0.000 description 1
- 244000052616 bacterial pathogen Species 0.000 description 1
- 229940077388 benzenesulfonate Drugs 0.000 description 1
- 230000008033 biological extinction Effects 0.000 description 1
- 230000015572 biosynthetic process Effects 0.000 description 1
- 239000011575 calcium Substances 0.000 description 1
- 229910052791 calcium Inorganic materials 0.000 description 1
- 125000003178 carboxy group Chemical group [H]OC(*)=O 0.000 description 1
- 150000001768 cations Chemical class 0.000 description 1
- 238000004140 cleaning Methods 0.000 description 1
- 230000000052 comparative effect Effects 0.000 description 1
- 230000000536 complexating effect Effects 0.000 description 1
- 238000005516 engineering process Methods 0.000 description 1
- 238000004880 explosion Methods 0.000 description 1
- 239000003906 humectant Substances 0.000 description 1
- 125000004435 hydrogen atom Chemical group [H]* 0.000 description 1
- 229910052500 inorganic mineral Inorganic materials 0.000 description 1
- 230000007774 longterm Effects 0.000 description 1
- 229910052751 metal Inorganic materials 0.000 description 1
- 239000002184 metal Substances 0.000 description 1
- 238000000034 method Methods 0.000 description 1
- 244000005700 microbiome Species 0.000 description 1
- 239000011707 mineral Substances 0.000 description 1
- 230000003020 moisturizing effect Effects 0.000 description 1
- 150000002762 monocarboxylic acid derivatives Chemical class 0.000 description 1
- 239000011591 potassium Substances 0.000 description 1
- 229910052700 potassium Inorganic materials 0.000 description 1
- 238000002360 preparation method Methods 0.000 description 1
- CZPZWMPYEINMCF-UHFFFAOYSA-N propaneperoxoic acid Chemical group CCC(=O)OO CZPZWMPYEINMCF-UHFFFAOYSA-N 0.000 description 1
- 235000019260 propionic acid Nutrition 0.000 description 1
- IUVKMZGDUIUOCP-BTNSXGMBSA-N quinbolone Chemical compound O([C@H]1CC[C@H]2[C@H]3[C@@H]([C@]4(C=CC(=O)C=C4CC3)C)CC[C@@]21C)C1=CCCC1 IUVKMZGDUIUOCP-BTNSXGMBSA-N 0.000 description 1
- 239000000344 soap Substances 0.000 description 1
- 239000011734 sodium Substances 0.000 description 1
- 229910052708 sodium Inorganic materials 0.000 description 1
- 238000010998 test method Methods 0.000 description 1
- DHCDFWKWKRSZHF-UHFFFAOYSA-L thiosulfate(2-) Chemical compound [O-]S([S-])(=O)=O DHCDFWKWKRSZHF-UHFFFAOYSA-L 0.000 description 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
- C11D—DETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
- C11D3/00—Other compounding ingredients of detergent compositions covered in group C11D1/00
- C11D3/39—Organic or inorganic per-compounds
- C11D3/3947—Liquid compositions
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N37/00—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom having three bonds to hetero atoms with at the most two bonds to halogen, e.g. carboxylic acids
- A01N37/16—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom having three bonds to hetero atoms with at the most two bonds to halogen, e.g. carboxylic acids containing the group; Thio analogues thereof
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C407/00—Preparation of peroxy compounds
- C07C407/003—Separation; Purification; Stabilisation; Use of additives
- C07C407/006—Stabilisation; Use of additives
-
- C—CHEMISTRY; METALLURGY
- C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
- C11D—DETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
- C11D3/00—Other compounding ingredients of detergent compositions covered in group C11D1/00
- C11D3/39—Organic or inorganic per-compounds
- C11D3/3945—Organic per-compounds
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Wood Science & Technology (AREA)
- Inorganic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Agronomy & Crop Science (AREA)
- Pest Control & Pesticides (AREA)
- Plant Pathology (AREA)
- Health & Medical Sciences (AREA)
- Dentistry (AREA)
- General Health & Medical Sciences (AREA)
- Zoology (AREA)
- Environmental Sciences (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Detergent Compositions (AREA)
Description
Oppfinnelsens gjenstand er vandige lagringsstabile konsentrater av mikrobicide henholdsvis oksyderende blandinger på basis av alifatiske monoperkarboksylsyrer samt H2O2. The object of the invention is aqueous storage-stable concentrates of microbicide or oxidizing mixtures based on aliphatic monopercarboxylic acids and H2O2.
Det er kjent at oppløsningen av pereddik- og perpropionsyre danner funksjonelle midler, disse kan finne anvendelse for forskjellige formål. De er eksempelvis egnet for oksydasjon av organisk material generelt samt til behandling av hår, strå og tekstiler. Spesielt kan de imidlertid an- It is known that the solution of peracetic acid and perpropionic acid forms functional agents, which can be used for various purposes. They are, for example, suitable for oxidation of organic material in general as well as for treating hair, straw and textiles. In particular, however, they can
vendes som mikrobicide og virucide midler. Fortrinnsvis finner pereddiksyre anvendelse. • are used as microbicide and virucidal agents. Peracetic acid is preferably used. •
De rene persyrer er imidlertid ikke bare proble-matiske med hensyn til deres fremstilling, men også på grunn av deres brann- og eksplosjonsfare vanskelig å håndtere. Der-for anvendes i praksis syren ikke i ren form, men i blandinger av eksempelvis 35 til H5% pereddiksyre og 40 til 55% eddiksyre. VAnndelen ligger vanligvis under 15%. Ulempen ved disse konsentrater ligger deri at de på grunn av deres stikkende lukt og deres etsende virkning bare kan håndteres ved forbrukeren som må i første rekke fortynne konsentratene under strenge sikkerhetsforholdsregler..Fremstiller man derimot konsentrater av eksempelvis 5 til 25 vekt% persyre alene og resten vann, så However, the pure peracids are not only problematic with regard to their production, but also because of their fire and explosion hazard, difficult to handle. In practice, the acid is therefore not used in its pure form, but in mixtures of, for example, 35 to H5% peracetic acid and 40 to 55% acetic acid. The proportion of water is usually below 15%. The disadvantage of these concentrates lies in the fact that, due to their pungent smell and their corrosive effect, they can only be handled by the consumer, who must first of all dilute the concentrates under strict safety precautions. On the other hand, concentrates are made from, for example, 5 to 25% by weight of peracid alone and the rest water, so
er disse ikke lagringsstabile. are these not shelf-stable.
Det er nå funnet at man kan unngå overnevnte ulemper og få lagringsstabile konsentrater av mikrobicide henholdsvis oksyderende blandinger på basis av alifatiske monoperkarboksylsyrer, når disse er karakterisert ved at de inneholder 0,5 til 20 vekt% persyre med 2 eller 3 karbonatomer og/eller tilsvarende alifatiske monokarboksylsyrer samt 25 It has now been found that one can avoid the above-mentioned disadvantages and obtain storage-stable concentrates of microbicide or oxidizing mixtures based on aliphatic monopercarboxylic acids, when these are characterized in that they contain 0.5 to 20% by weight peracid with 2 or 3 carbon atoms and/or equivalent aliphatic monocarboxylic acids as well as 25
til 40 vekt% h^CUjVann, samt eventuelt fosfonsyre og/eller fuktemidler. to 40% by weight h^CUjWater, as well as possibly phosphonic acid and/or wetting agents.
Fortrinnsvis er de lagringsstabile H202-holdige konsentrater karakterisert ved et innhold av 5 til 10 vekt/S pereddiksyre og/eller eddiksyre samt et molart overskudd av # 2®2 til Persyre> sistnevnte beregnet som monokarboksylsyre, Preferably, the storage-stable H202-containing concentrates are characterized by a content of 5 to 10 wt/S peracetic acid and/or acetic acid and a molar excess of # 2®2 to Peracid> the latter calculated as monocarboxylic acid,
på minst 2 : 1, fortrinnsvis 3 : 1 til 50 : 1. Fremstillingen foregår på enkel måte ved sammenblanding av H202-oppløsning, fortrinnsvis med en konsentrasjon på ca. 33 vekt$ med pereddiksyre og eventuelt eddiksyre. På fordelaktig måte kan man også fremstille blandingene, idet man bare blander den konsentrerte H202-oppløsning med den tilsvarende eddiksyremengde. Da pro-duktene for det meste ikke direkte tilføres til forbrukeren, men først lagres innstiller det seg et tilsvarende innhold av pereddiksyre. Pereddiksyredannelsen kan hvis ønsket akseller-eres katalytisk med en liten mengde mineralsyre (0,1 til 1%). Vanligvis er imidlertid en slik tilsetning ikke nødvendig av overnevnte grunner. of at least 2:1, preferably 3:1 to 50:1. The preparation takes place in a simple way by mixing H2O2 solution, preferably with a concentration of approx. 33 wt$ with peracetic acid and possibly acetic acid. In an advantageous manner, the mixtures can also be prepared by simply mixing the concentrated H 2 O 2 solution with the corresponding amount of acetic acid. As the products are mostly not directly supplied to the consumer, but first stored, a corresponding content of peracetic acid is established. The formation of peracetic acid can, if desired, be accelerated catalytically with a small amount of mineral acid (0.1 to 1%). Usually, however, such an addition is not necessary for the above reasons.
Slike konsentrater som eksempelvis er fremstillet av 30$ H202, 5% eddiksyre og 65% vann har ingen forstyrrende lukt mer og er lett å håndtere, dvs. de kan lett fortynnes til de i næringsmiddelteknologien og i den medisinske sektor vanlige anvendelseskonsentrasjoner fra 0,1 til 1% uten at det er nødvendig med betraktelige forsiktighetsforholdsregler. Such concentrates, for example made from 30$ H202, 5% acetic acid and 65% water, no longer have a disturbing smell and are easy to handle, i.e. they can be easily diluted to the usual application concentrations in the food technology and medical sector from 0.1 to 1% without the need for considerable precautionary measures.
Det ble videre funnet at man får konsentrater for fremstilling av mikrobicide midler med øket virkning på basis av de overnevnte komponenter, når disse i tillegg inneholder 0,25 til 10 vekt# fosfonsyre eller deres sure salter. It was further found that concentrates for the production of microbicide agents with increased effect are obtained on the basis of the above-mentioned components, when these additionally contain 0.25 to 10% by weight of phosphonic acid or their acid salts.
Med fosfonsyre er det innen oppfinnelsens ramme With phosphonic acid, it is within the scope of the invention
å forstå slike som er i stand til å binde komplekst toverdige metallkationer, spesielt kalsium. Det kommer således i betraktning et større antall' fosfonsyrery som- foruten fosfonsyre-gruppene eventuelt dessuten kan inneholde også karboksylgrupper. Egnede fosfonsyrer er således, forbindelser med formlene to understand those capable of complexing divalent metal cations, especially calcium. Thus, a larger number of phosphonic acids are taken into consideration which, in addition to the phosphonic acid groups, can optionally also contain carboxyl groups. Suitable phosphonic acids are thus compounds with the formulas
idet R, betyr fenylrest, cykloalkylrest eller alkylrest med 1 til 6 C-atomer, R2 og R, betyr hydrogenatom eller alkyl- ' rest med 1 til 4 C-atomer eller forbindelser som where R means phenyl radical, cycloalkyl radical or alkyl radical with 1 to 6 C atoms, R 2 and R , means hydrogen atom or alkyl radical with 1 to 4 C atoms or compounds which
aminotrimetylenfosfonsyre, aminotrimethylenephosphonic acid,
dimetylaminometandifosfonsyre, dimethylaminomethanediphosphonic acid,
aminoeddiksyre-N-N-dimetylenfosfonsyre, aminoacetic acid-N-N-dimethylphosphonic acid,
etylendiamin-tetrametylen-fosfonsyre, ethylenediamine-tetramethylene-phosphonic acid,
3-aminopropan-l-hydroksy-l,1-difosfonsyre, 3-aminopropane-1-hydroxy-1,1-diphosphonic acid,
2-fosfonobutan-1,2,4-trikarboksylsyre, 2-phosphonobutane-1,2,4-tricarboxylic acid,
fosfonoravsyre samt phosphonosuccinic acid as well
1-fosfono-l-metylravsyre. 1-phosphono-l-methylsuccinic acid.
Spesielt kommer det i betraktning In particular, it comes into consideration
dimetylaminometandifos fonsyre, dimethylaminomethane diphosphonic acid,
1-amino-l-fenyImetandifosfonsyre, 1-amino-1-phenylmethanediphosphonic acid,
aminotrimetylenfosfonsyre, aminotrimethylenephosphonic acid,
aminoeddiksyre-N-N-dimetylenfosfonsyre, aminoacetic acid-N-N-dimethylphosphonic acid,
1-hydroksyetan-1,1-difos fonsyre. 1-hydroxyethane-1,1-diphosphonic acid.
Istedenfor de anførte fosfonsyrer kan det også anvendes deres sure vannoppløselige salter som spesielt natrium-, kalium-, ammonium- eller alkanolaminsalter.. Hvis' ønsket kan det også finne anvendelse blandinger av de enkelte fosfonsyrer eller deres sure salter. Instead of the listed phosphonic acids, their acidic water-soluble salts can also be used, such as sodium, potassium, ammonium or alkanolamine salts. If desired, mixtures of the individual phosphonic acids or their acidic salts can also be used.
Ved den mangesidige anvendelsesmulighet - av overnevnte funksjonelle midler, eksempelvis for oksydasjon av organisk material generelt eller til behandling av hår, strå eller tekstiler samt som mikrobicide og virucide midler er det i mange tilfeller fordelaktig å anvende disse samtidig og under tilsetning av et fuktemiddel for ytterligere å forbedre de ønsk-ede egenskaper. Due to the many-sided possibility of application - of the above-mentioned functional agents, for example for oxidation of organic material in general or for the treatment of hair, straw or textiles as well as as microbicide and virucidal agents, it is in many cases advantageous to use these at the same time and with the addition of a wetting agent for further to improve the desired characteristics.
Det ble funnet at man får lagringsstabile konsentrater av overnevnte type, når man tilsetter anionaktive fuktemidler i form av alkylbenzensulfonat, alkylsulfat og/eller alkylsulfonat i mengder fra 0,05 til 5 vekt/S. It was found that storage-stable concentrates of the above-mentioned type are obtained when anionic wetting agents in the form of alkylbenzene sulphonate, alkyl sulphate and/or alkyl sulphonate are added in amounts from 0.05 to 5 wt/S.
Som alkylbenzensulfonater kommer det i betraktning slike som inneholder en alkylrest fra 6 til 18 karbonatomer,. fortrinnsvis 9 til 15 karbonatomer. Istedenfor alkylbenzensulfonater kommer det også i betraktning alkylsulfater eller alkylsulfonater med en alkylrest av kjedelengde 12 til 18 karbonatomer. Hvis ønsket kan det selvsagt også anvendes blandinger av de nevnte anionaktive fuktemidler.^As alkylbenzenesulfonates, those which contain an alkyl residue from 6 to 18 carbon atoms come into consideration. preferably 9 to 15 carbon atoms. Instead of alkylbenzene sulfonates, alkyl sulfates or alkyl sulfonates with an alkyl residue of chain length 12 to 18 carbon atoms are also considered. If desired, mixtures of the aforementioned anionic wetting agents can of course also be used.^
Det har vist'seg at de nevnte tilsetninger også forblir stabile over lengre tidsrom i konsentratene og således bibeholdes også konstant innholdet av pereddiksyrekonsen-tratet. Anvender man derimot som fuktemiddeltilsetning såper eller de vanlige ikke-ionogene fuktemidler, så oppnås ikke en tilstrekkelig stabilitet. It has been shown that the aforementioned additives also remain stable over a longer period of time in the concentrates and thus the content of the peracetic acid concentrate is also maintained constantly. If, on the other hand, soaps or the usual non-ionic wetting agents are used as humectants, sufficient stability is not achieved.
De nye lagringsstabile konsentrater av de omtalte funksjonelle midler kan finne anvendelse for alle formål, hvor det skal oppnås en fuktende og oksyderende virkning og ulempene ved de kjente rene persyrer vanskeliggjør eller utelukker deres anvendbarhet. Midlene har videre også den fordel at de er egnet til standdesinfeksjon for å hindre en sekundær kim-formering på maskiner, som spesielt i næringsmiddelindustrien etter rensning. Ved deres mengde av H2C>2 opptrer det forøvrig en langtidsvirkning overfor de fleste mikroorganismer. The new storage-stable concentrates of the mentioned functional agents can be used for all purposes, where a moisturizing and oxidizing effect is to be achieved and the disadvantages of the known pure peracids make it difficult or exclude their applicability. The agents also have the advantage that they are suitable for stand disinfection to prevent a secondary germ multiplication on machines, which is particularly the case in the food industry after cleaning. Their amount of H2C>2 also has a long-term effect on most microorganisms.
pH-verdien av bruksoppløsningen er ennu svakt sur og eddiksyreresiduet er etter desinfeksjonen meget liten, således at midlene også egner seg for en desinfeksjon hvor en spyling ikke mere er nødvendig. The pH value of the solution for use is still slightly acidic and the acetic acid residue after disinfection is very small, so that the agents are also suitable for a disinfection where a flush is no longer necessary.
E ksempel 1. Example 1.
Det ble■fremstillet et konsentrat til fremstilling av mikrobicide midler ved sammenblanding av A concentrate for the production of microbicidal agents was produced by mixing together
5 vekt? eddiksyre, 5 weight? acetic acid,
30 vekt? H202, 30 weight? H202,
65 vekt? vann. 65 weight? water.
Konsentratet hensettes og i bestemte tid"srom uttas en prøve til bestemmelse av innholdet av H202 og pereddiksyre. Resultatene er gjengitt i nedenstående tabell 1. Til sammenligning ble det fremstillet et ytterligere konsentrat som inneholdt 8 vekt? pereddiksyre, 8,5 vekt? eddiksyre, 1 vekt? H202 samt 82,5 vekt? vann. Fra blandingen ble det etter bestemte tidsrom uttatt prøver og innholdet av pereddiksyre bestemt. Resultatene er gjengitt i tabell 2. Det sees tydelig at midlene ikke er stabile. The concentrate is set aside and a sample is taken over a certain period of time to determine the content of H202 and peracetic acid. The results are shown in Table 1 below. For comparison, a further concentrate was prepared which contained 8% by weight of peracetic acid, 8.5% by weight of acetic acid, 1 weight of H202 and 82.5 weight of water. Samples were taken from the mixture after certain periods of time and the content of peracetic acid determined. The results are reproduced in table 2. It is clearly seen that the agents are not stable.
Eksempel 2. Example 2.
Det ble fremstillet konsentrater av den nedenfor angitte sammensetning (produkt A til C) av t^C^, eddiksyre og vann. Disse konsentrater ble hensatt en tid og deretter fortynnet til en 0,05 resp. 0,2 vekt?-ig oppløsning. Deretter ble det bestemt den mikrobicide virkning i suspensjonsprøven etter retningslinjene for Deutschen Gesellschaft fur Hygiene und Mikrobiologie (DGHM). Verdiene (utrydningstider i minutter) er gjengitt i følgende tabell 3. Concentrates of the composition indicated below (product A to C) were prepared from t^C^, acetic acid and water. These concentrates were set aside for a time and then diluted to a 0.05 resp. 0.2 wt?-ig solution. The microbicidal effect in the suspension sample was then determined according to the guidelines of the Deutschen Gesellschaft fur Hygiene und Mikrobiologie (DGHM). The values (eradication times in minutes) are reproduced in the following table 3.
Forsøkene ble gjentatt etter at konsentratet var lagret over lengere tid. The experiments were repeated after the concentrate had been stored for a longer period of time.
Produkter (angivelse i vekt?) Products (statement by weight?)
Eksempel 3» Example 3»
Under anvendelse av suspensjonsprøven etter ret-ningslinjer for DGHM ble det bestemt utrydningstider av Staphylococcus aureus ved hjelp av blandinger av H2<02 og mindre mengder av eddiksyre resp. propionsyre. Resultatene er gjengitt i følgende tabell 4. Using the suspension sample according to guidelines for DGHM, eradication times of Staphylococcus aureus were determined using mixtures of H2<02 and smaller amounts of acetic acid or propionic acid. The results are reproduced in the following table 4.
Eksempel 4. Example 4.
Det ble fremstillet konsentrater av 33 vekt? H202, 5 vekt? eddiksyre, 0,5 vekt? fosfonsyre, resten vann. Concentrates of 33 wt? H202, 5 weight? acetic acid, 0.5 weight? phosphonic acid, the rest water.
Til de enkelte konsentrater ble det satt følgende fosfonsyrer. The following phosphonic acids were added to the individual concentrates.
A) Dimetylaminometandifosfonsyre. A) Dimethylaminomethanediphosphonic acid.
B) 1-amino-l-fenylmetandifosfonsyre. B) 1-amino-1-phenylmethanediphosphonic acid.
C) Aminotrimetylenfosfonsyre. C) Aminotrimethylenephosphonic acid.
D) Aminoeddiksyre-N,N-dimetylenfosfonsyre. D) Aminoacetic acid-N,N-dimethylphosphonic acid.
E) 1-hydroksyetan-l,1-difosfbnsyfe. E) 1-hydroxyethane-1,1-diphosphine.
F) 1-amino-l-cykloheksy1-1,1-difosfonsyre. F) 1-amino-1-cyclohexyl-1,1-diphosphonic acid.
G) 1-N-metylaminoetan-l,1-difosfonsyre. G) 1-N-methylaminoethane-1,1-diphosphonic acid.
H) Etylendiamin-tetrametylen-fosfonsyre. H) Ethylenediamine-tetramethylene-phosphonic acid.
For å få en sammenligningsverdi ble det til et ytterligerekonsentrat ikke satt fosfonsyre. In order to obtain a comparative value, no phosphonic acid was added to a further concentrate.
Konsentratene ble hensatt en tid og deretter fortynnet til en konsentrasjon på 0,1?. Det ble gjennomført mikrobicid virkning i suspensjonsprøvene etter retningslinjene for Deutschen Gesellschaft fur Hygiene und Mikrobiologie (DGHM). Som prøvestamme ble det anvendt Staphylococcus aureus og Escheria coli. The concentrates were set aside for a time and then diluted to a concentration of 0.1%. Microbicidal activity was carried out in the suspension samples according to the guidelines of the Deutschen Gesellschaft fur Hygiene und Mikrobiologie (DGHM). Staphylococcus aureus and Escheria coli were used as test strains.
De fundne utrydningstider i minutter er gjengitt i følgende tabell 5. The found extinction times in minutes are reproduced in the following table 5.
E ksempel 5 . Example 5.
Det ble fremstillet lagringsstabile konsentrater av 33% H202, 5% eddiksyre, 3% fosforsyre resp. 1-hydroksyetan-1,1-difosfonsyre resp. 2-fosfonobutan-l,2,4-di-karboksylsyre. Konsentratene ble hensatt 8 dager og deretter fortynnet til en anvendelseskonsentrasjon på 0,05?. Storage-stable concentrates of 33% H202, 5% acetic acid, 3% phosphoric acid or 1-hydroxyethane-1,1-diphosphonic acid resp. 2-phosphonobutane-1,2,4-dicarboxylic acid. The concentrates were left for 8 days and then diluted to a use concentration of 0.05%.
Den mikrobicide virkning ble fastslått ved hjelp av kimreduksjonen "D". Derved ble det anvendt følgende prøve-metode. The microbicidal effect was determined by means of the germ reduction "D". Thereby, the following test method was used.
0,1 ml av en kimsuspensjon (kimtall 108/ml) settes til 10 ml desinfeksjonsoppløsning (resp. som. kontrollverdi til 10 ml vann), blandingen omrøres 5 minutter, 0,1 ml uttas og haes i 10 ml avhemmingsoppløsning (0,5?-ig vandig tiosulfat-oppløsning). Herav ble det etter 15 minutter etter den Kochske platefremgangsmåte bestemt kimtallet. 0.1 ml of a germ suspension (germ count 108/ml) is added to 10 ml of disinfection solution (or as a control value to 10 ml of water), the mixture is stirred for 5 minutes, 0.1 ml is taken out and placed in 10 ml of deinhibition solution (0.5 ?-ig aqueous thiosulphate solution). From this, the germ count was determined after 15 minutes using the Koch plate method.
Vurderingen foregikk etter formel The assessment took place according to a formula
D angir altså kimreduksjonen kvantitativt i loga-ritmisk form, f.eks. D = 1, betyr at kiihtallet ble redusert med en tierpotens. D therefore indicates the germ reduction quantitatively in logarithmic form, e.g. D = 1, means that the kiih number was reduced by a third power.
Sammenlignings forsøk med en tilsetning av fosforsyre viser at innvirkningen av aciditeten av de tilsatte fosfonsyrer ikke er avgjørende (se tabell 6). Comparison tests with the addition of phosphoric acid show that the effect of the acidity of the added phosphonic acids is not decisive (see table 6).
I IN
Anmerkning: Angivelsen "over" før D-verdien betyr at alle Note: The indication "above" before the D value means that all
kimer er utryddet. germs are eradicated.
Eksempel 6. Example 6.
Det ble fremstillet et konsentrat ved sammenblanding av A concentrate was produced by mixing
5,0 vekt? eddiksyre, 5.0 weight? acetic acid,
27,6 vekt? H202, 27.6 weight? H202,
1,0 vekt? alkyl-(C12-C1g-sulfonat) samt 1.0 weight? alkyl-(C12-C1g-sulfonate) as well as
66,4 vekt? vann. 66.4 weight? water.
Konsentratet ble hensatt og i bestemte tidsrom uttatt en prøve til bestemmelse av innholdet av H202 og pereddiksyre. Resultatene er gjengitt i følgende tabell 7« Tabell 7. Blandingens stabilitet ved tilsetning av et alkyl-sulf onat. The concentrate was set aside and at specific intervals a sample was taken to determine the content of H202 and peracetic acid. The results are reproduced in the following table 7« Table 7. Stability of the mixture when an alkyl sulphonate is added.
Praktisk talt de samme resultater får man når konsentratene istedenfor 1? alkylsulfonat inneholder 1? alkylsulfat. Practically the same results are obtained when the concentrates instead of 1? alkyl sulfonate contains 1? alkyl sulfate.
Eksempel J . Example J .
Det ble fremstillet et konsentrat for fremstilling av mikrobicid middel ved sammenblanding av A concentrate was produced for the production of microbicide by mixing
5 vekt? eddiksyre, 5 weight? acetic acid,
27,6 vekt? H20227.6 weight? H202
1,5 vekt? hydroksyetan-1,1-difosfonsyre, 1.5 weight? hydroxyethane-1,1-diphosphonic acid,
1,5 vekt? alkyl-(C12)-benzensulfonat samt 1.5 weight? alkyl-(C12)-benzenesulfonate as well as
64,4 vekt? vann. 64.4 weight? water.
Konsentratet ble oppdelt i to halvdeler og hensatt ved temperaturer på 20 resp. 40°C og i bestemte tidsrom ble det uttatt prøver til bestemmelse av innholdet av H202 pereddiksyre. Resultatene er gjengitt i følgende tabell 8. Det sees tydelig at konsentratene også er stabile ved nærvær av det angitte fuktemiddel over lengre tid. The concentrate was divided into two halves and stored at temperatures of 20 and 40°C and for certain periods of time, samples were taken to determine the content of H202 peracetic acid. The results are reproduced in the following table 8. It is clearly seen that the concentrates are also stable in the presence of the indicated wetting agent over a longer period of time.
Tabell 8. Table 8.
Innhold av hydrogenperoksyd og pereddiksyre ved 20 og 40°C i avhengighet av tiden. Content of hydrogen peroxide and peracetic acid at 20 and 40°C depending on the time.
Claims (5)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE19752536618 DE2536618C2 (en) | 1975-08-16 | 1975-08-16 | Concentrates of microbicidal agents |
| DE2536617A DE2536617B2 (en) | 1975-08-16 | 1975-08-16 | Storage-stable concentrates of functional agents based on peracetic or perproplonic acids and hydrogen peroxide |
| DE19762616049 DE2616049A1 (en) | 1976-04-12 | 1976-04-12 | Permonocarboxylic aq. concentrate stable to storage - contg. percarboxylic and/or carboxylic acid, hydrogen peroxide and water |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| NO762605L NO762605L (en) | 1977-02-17 |
| NO146697B true NO146697B (en) | 1982-08-16 |
| NO146697C NO146697C (en) | 1982-11-24 |
Family
ID=27186493
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO762605A NO146697C (en) | 1975-08-16 | 1976-07-26 | Aqueous storage-stable concentrates of microbicides by way of oxidizing mixtures based on percarboxylic acids and hydrogen peroxide |
Country Status (8)
| Country | Link |
|---|---|
| AR (1) | AR209191A1 (en) |
| BR (1) | BR7605307A (en) |
| CH (1) | CH620676A5 (en) |
| DK (1) | DK156026C (en) |
| FI (1) | FI63222C (en) |
| IT (1) | IT1074028B (en) |
| NO (1) | NO146697C (en) |
| SE (1) | SE438424B (en) |
-
1976
- 1976-07-26 SE SE7608459A patent/SE438424B/en not_active IP Right Cessation
- 1976-07-26 NO NO762605A patent/NO146697C/en unknown
- 1976-07-26 FI FI762128A patent/FI63222C/en not_active IP Right Cessation
- 1976-07-26 DK DK336376A patent/DK156026C/en not_active IP Right Cessation
- 1976-08-06 IT IT26091/76A patent/IT1074028B/en active
- 1976-08-11 AR AR264301A patent/AR209191A1/en active
- 1976-08-13 BR BR7605307A patent/BR7605307A/en unknown
- 1976-08-13 CH CH1036276A patent/CH620676A5/en not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| DK336376A (en) | 1977-02-17 |
| IT1074028B (en) | 1985-04-17 |
| FI762128A (en) | 1977-02-17 |
| CH620676A5 (en) | 1980-12-15 |
| FI63222C (en) | 1983-05-10 |
| NO762605L (en) | 1977-02-17 |
| FI63222B (en) | 1983-01-31 |
| AR209191A1 (en) | 1977-03-31 |
| BR7605307A (en) | 1977-08-09 |
| SE438424B (en) | 1985-04-22 |
| NO146697C (en) | 1982-11-24 |
| SE7608459L (en) | 1977-02-17 |
| DK156026C (en) | 1989-11-06 |
| DK156026B (en) | 1989-06-19 |
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