NO143943C - Analogifremgangsmaate ved fremstilling av terapeutisk aktiv 3-(4-p-fluorfenyl-1-metylbutyl)-1-hydroksy-6,6,9-trimetyl-7,8,9,10-tetrahydro-6h-dibenzo(b,d)pyran - Google Patents

Analogifremgangsmaate ved fremstilling av terapeutisk aktiv 3-(4-p-fluorfenyl-1-metylbutyl)-1-hydroksy-6,6,9-trimetyl-7,8,9,10-tetrahydro-6h-dibenzo(b,d)pyran

Info

Publication number
NO143943C
NO143943C NO741140A NO741140A NO143943C NO 143943 C NO143943 C NO 143943C NO 741140 A NO741140 A NO 741140A NO 741140 A NO741140 A NO 741140A NO 143943 C NO143943 C NO 143943C
Authority
NO
Norway
Prior art keywords
trimetyl
fluorphenyl
dibenzo
pyran
tetrahydro
Prior art date
Application number
NO741140A
Other languages
English (en)
Other versions
NO741140L (no
NO143943B (no
Inventor
Martin Winn
Kathleen Riley Lynn
Yvonne Connolly Martin
Original Assignee
Abbott Lab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Abbott Lab filed Critical Abbott Lab
Publication of NO741140L publication Critical patent/NO741140L/no
Publication of NO143943B publication Critical patent/NO143943B/no
Publication of NO143943C publication Critical patent/NO143943C/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D213/28—Radicals substituted by singly-bound oxygen or sulphur atoms
    • C07D213/30—Oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C37/00—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom of a six-membered aromatic ring
    • C07C37/01—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom of a six-membered aromatic ring by replacing functional groups bound to a six-membered aromatic ring by hydroxy groups, e.g. by hydrolysis
    • C07C37/055—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom of a six-membered aromatic ring by replacing functional groups bound to a six-membered aromatic ring by hydroxy groups, e.g. by hydrolysis the substituted group being bound to oxygen, e.g. ether group
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D213/44—Radicals substituted by doubly-bound oxygen, sulfur, or nitrogen atoms, or by two such atoms singly-bound to the same carbon atom
    • C07D213/46—Oxygen atoms
    • C07D213/50—Ketonic radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/78—Ring systems having three or more relevant rings
    • C07D311/80—Dibenzopyrans; Hydrogenated dibenzopyrans
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/94—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems condensed with rings other than six-membered or with ring systems containing such rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pyrane Compounds (AREA)
NO741140A 1973-04-02 1974-03-29 Analogifremgangsmaate ved fremstilling av terapeutisk aktiv 3-(4-p-fluorfenyl-1-metylbutyl)-1-hydroksy-6,6,9-trimetyl-7,8,9,10-tetrahydro-6h-dibenzo(b,d)pyran NO143943C (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US34594473A 1973-04-02 1973-04-02
US442034A US3901926A (en) 1973-04-02 1974-02-13 Alkylphenyl benzopyrans

Publications (3)

Publication Number Publication Date
NO741140L NO741140L (no) 1974-10-03
NO143943B NO143943B (no) 1981-02-02
NO143943C true NO143943C (no) 1981-05-13

Family

ID=26994624

Family Applications (1)

Application Number Title Priority Date Filing Date
NO741140A NO143943C (no) 1973-04-02 1974-03-29 Analogifremgangsmaate ved fremstilling av terapeutisk aktiv 3-(4-p-fluorfenyl-1-metylbutyl)-1-hydroksy-6,6,9-trimetyl-7,8,9,10-tetrahydro-6h-dibenzo(b,d)pyran

Country Status (12)

Country Link
US (1) US3901926A (no)
JP (1) JPS5035168A (no)
CA (1) CA1010455A (no)
CH (1) CH595375A5 (no)
DE (1) DE2415697A1 (no)
FI (1) FI60004C (no)
FR (1) FR2223042B1 (no)
GB (1) GB1459564A (no)
NL (1) NL7404150A (no)
NO (1) NO143943C (no)
PH (1) PH12327A (no)
SE (1) SE413244B (no)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1522057A (en) * 1975-11-03 1978-08-23 Pfizer 9-hydroxydibenzo(b,d)pyrans and intermediates therefor
US4018777A (en) * 1975-11-14 1977-04-19 Abbott Laboratories 2-Substituted-5-alkyl resorcinols
US4051152A (en) * 1976-01-07 1977-09-27 Sharps Associates Oxo C-ring benzopyrans
US4036857A (en) * 1976-02-02 1977-07-19 Sharps Associates Benzopyrans having an unsaturated side chain
US4247557A (en) * 1976-08-04 1981-01-27 Abbott Laboratories Benzopyranopyridines as antiglaucoma agents
US4136183A (en) * 1976-08-04 1979-01-23 Abbott Laboratories Benzopyranopyridines as antiglaucoma agents
US4235913A (en) * 1977-06-07 1980-11-25 Pfizer Inc. 9-Hydroxyhexahydrodibeno[b,d]pyrans, 1-substituted-9-hydroxyhexahydrodibenzo]b,d]pyrans
US4209520A (en) * 1977-06-17 1980-06-24 Pfizer Inc. Hexahydro-1-hydroxy-9-hydroxymethyl-3-substituted-6H-dibenzo[b,d]pyrans as analgesic agents
US4133819A (en) * 1977-06-17 1979-01-09 Pfizer Inc. Hexahydro-1-hydroxy-9-hydroxymethyl-3-substituted-6H-dibenzo[b,d]pyrans as analgesic agents
US4292316A (en) * 1978-10-02 1981-09-29 Abbott Laboratories Antiglaucoma agents
US4454144A (en) * 1982-06-21 1984-06-12 Pfizer Inc. Substituted dibenzo[b,d]pyran analgesics
AU2002359283B2 (en) * 2001-11-19 2007-06-21 Eli Lilly And Company Substituted benzopyrans as selective estrogen receptor-beta agonists
CA2496097A1 (en) * 2002-08-23 2004-03-04 University Of Connecticut Keto cannabinoids with therapeutic indications
CA2526103A1 (en) * 2003-05-20 2004-12-29 Bob M. Ii Moore Cannabinoid derivatives, methods of making, and use thereof

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2509386A (en) * 1950-05-30 Debenzopyran marihuana-like
US3639426A (en) * 1970-01-08 1972-02-01 Little Inc A 4-oxo-9-hydroxy-7-(3-methyl-2-octyl)-1 2 3 4-tetrahydrocyclopenta(c)(1)benzopyran
US3799946A (en) * 1972-03-13 1974-03-26 Smithkline Corp Dibenzo(b,d)pyran compounds

Also Published As

Publication number Publication date
NL7404150A (no) 1974-10-04
NO741140L (no) 1974-10-03
FR2223042B1 (no) 1977-05-06
DE2415697A1 (de) 1974-10-17
GB1459564A (en) 1976-12-22
FR2223042A1 (no) 1974-10-25
CA1010455A (en) 1977-05-17
PH12327A (en) 1979-01-16
FI60004C (fi) 1981-11-10
AU6664074A (en) 1975-09-18
CH595375A5 (no) 1978-02-15
JPS5035168A (no) 1975-04-03
NO143943B (no) 1981-02-02
SE413244B (sv) 1980-05-12
US3901926A (en) 1975-08-26
FI60004B (fi) 1981-07-31

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