NO119682B - - Google Patents
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- Publication number
- NO119682B NO119682B NO1729/68A NO172968A NO119682B NO 119682 B NO119682 B NO 119682B NO 1729/68 A NO1729/68 A NO 1729/68A NO 172968 A NO172968 A NO 172968A NO 119682 B NO119682 B NO 119682B
- Authority
- NO
- Norway
- Prior art keywords
- acetylsalicylic acid
- ethyl ether
- piperazine
- piperazinium
- bis
- Prior art date
Links
- RTZKZFJDLAIYFH-UHFFFAOYSA-N Diethyl ether Chemical compound CCOCC RTZKZFJDLAIYFH-UHFFFAOYSA-N 0.000 claims description 24
- GLUUGHFHXGJENI-UHFFFAOYSA-N Piperazine Chemical compound C1CNCCN1 GLUUGHFHXGJENI-UHFFFAOYSA-N 0.000 claims description 16
- BSYNRYMUTXBXSQ-UHFFFAOYSA-N Aspirin Chemical compound CC(=O)OC1=CC=CC=C1C(O)=O BSYNRYMUTXBXSQ-UHFFFAOYSA-N 0.000 claims description 15
- 229960001138 acetylsalicylic acid Drugs 0.000 claims description 14
- 238000000034 method Methods 0.000 claims description 6
- YOAMPPADXGVWIC-UHFFFAOYSA-N C(C)(=O)OC=1C(C(=O)[O-])=CC=CC1.C(C)(=O)OC=1C(C(=O)[O-])=CC=CC1.[NH2+]1CCNCC1.[NH2+]1CCNCC1 Chemical compound C(C)(=O)OC=1C(C(=O)[O-])=CC=CC1.C(C)(=O)OC=1C(C(=O)[O-])=CC=CC1.[NH2+]1CCNCC1.[NH2+]1CCNCC1 YOAMPPADXGVWIC-UHFFFAOYSA-N 0.000 claims description 5
- 239000003960 organic solvent Substances 0.000 claims description 2
- 238000002360 preparation method Methods 0.000 claims description 2
- 239000002904 solvent Substances 0.000 claims 1
- 150000003839 salts Chemical class 0.000 description 10
- QTBSBXVTEAMEQO-UHFFFAOYSA-N Acetic acid Chemical compound CC(O)=O QTBSBXVTEAMEQO-UHFFFAOYSA-N 0.000 description 9
- 150000001875 compounds Chemical class 0.000 description 3
- 230000003301 hydrolyzing effect Effects 0.000 description 3
- 238000004519 manufacturing process Methods 0.000 description 3
- 238000002844 melting Methods 0.000 description 3
- 230000008018 melting Effects 0.000 description 3
- 238000009835 boiling Methods 0.000 description 2
- 238000006243 chemical reaction Methods 0.000 description 2
- 238000003776 cleavage reaction Methods 0.000 description 2
- 230000007062 hydrolysis Effects 0.000 description 2
- 238000006460 hydrolysis reaction Methods 0.000 description 2
- 230000007017 scission Effects 0.000 description 2
- 239000000126 substance Substances 0.000 description 2
- VZGDMQKNWNREIO-UHFFFAOYSA-N tetrachloromethane Chemical compound ClC(Cl)(Cl)Cl VZGDMQKNWNREIO-UHFFFAOYSA-N 0.000 description 2
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 2
- 125000002777 acetyl group Chemical group [H]C([H])([H])C(*)=O 0.000 description 1
- 230000002378 acidificating effect Effects 0.000 description 1
- 230000000202 analgesic effect Effects 0.000 description 1
- 230000001754 anti-pyretic effect Effects 0.000 description 1
- 239000002221 antipyretic Substances 0.000 description 1
- 239000012043 crude product Substances 0.000 description 1
- 239000013078 crystal Substances 0.000 description 1
- 238000000354 decomposition reaction Methods 0.000 description 1
- 238000001914 filtration Methods 0.000 description 1
- 125000000524 functional group Chemical group 0.000 description 1
- 239000000047 product Substances 0.000 description 1
- 150000003870 salicylic acids Chemical class 0.000 description 1
- 230000035945 sensitivity Effects 0.000 description 1
- 239000007787 solid Substances 0.000 description 1
- 238000003756 stirring Methods 0.000 description 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/02—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms containing only hydrogen and carbon atoms in addition to the ring hetero elements
- C07D295/027—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms containing only hydrogen and carbon atoms in addition to the ring hetero elements containing only one hetero ring
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US63602567A | 1967-05-04 | 1967-05-04 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| NO119682B true NO119682B (pm) | 1970-06-22 |
Family
ID=24550080
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO1729/68A NO119682B (pm) | 1967-05-04 | 1968-05-03 |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US3528983A (pm) |
| BE (1) | BE714626A (pm) |
| CH (1) | CH487905A (pm) |
| ES (1) | ES353550A1 (pm) |
| FR (1) | FR7712M (pm) |
| GB (1) | GB1126679A (pm) |
| NL (1) | NL6806250A (pm) |
| NO (1) | NO119682B (pm) |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3227718A (en) * | 1966-01-04 | Novel anthelminttc agents and process for producing the same | ||
| US2753350A (en) * | 1951-11-01 | 1956-07-03 | Hasselstrom Torsten | Pungent-tasting pentavalent piperazine diacid salts |
| US2819268A (en) * | 1955-10-26 | 1958-01-07 | Baisse Jacques | New chemical compound and its method of preparation |
| US2842548A (en) * | 1956-01-30 | 1958-07-08 | American Cyanamid Co | Piperazine compounds and method of preparation thereof |
| US2980681A (en) * | 1957-10-14 | 1961-04-18 | Parke Davis & Co | Salt of piperazine and 2, 4, 5-trichlorophenol |
| US3019226A (en) * | 1959-04-10 | 1962-01-30 | Olin Mathieson | Piperazine salt of phytic acid |
| GB1048084A (en) * | 1963-08-14 | 1966-11-09 | Ici Ltd | Benzanilide derivatives |
-
1967
- 1967-05-04 US US636025A patent/US3528983A/en not_active Expired - Lifetime
- 1967-08-30 GB GB39678/67A patent/GB1126679A/en not_active Expired
-
1968
- 1968-05-02 NL NL6806250A patent/NL6806250A/xx unknown
- 1968-05-03 NO NO1729/68A patent/NO119682B/no unknown
- 1968-05-03 CH CH659268A patent/CH487905A/de not_active IP Right Cessation
- 1968-05-03 BE BE714626D patent/BE714626A/xx unknown
- 1968-05-04 ES ES353550A patent/ES353550A1/es not_active Expired
- 1968-05-06 FR FR150636A patent/FR7712M/fr not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| NL6806250A (pm) | 1968-11-05 |
| GB1126679A (en) | 1968-09-11 |
| BE714626A (pm) | 1968-09-30 |
| FR7712M (pm) | 1970-03-02 |
| ES353550A1 (es) | 1969-10-01 |
| CH487905A (de) | 1970-03-31 |
| US3528983A (en) | 1970-09-15 |
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