NL950023I2 - Radionuclide isonitrilcomplexen voor merkende en beeldvormende middelen. - Google Patents

Radionuclide isonitrilcomplexen voor merkende en beeldvormende middelen.

Info

Publication number
NL950023I2
NL950023I2 NL950023C NL950023C NL950023I2 NL 950023 I2 NL950023 I2 NL 950023I2 NL 950023 C NL950023 C NL 950023C NL 950023 C NL950023 C NL 950023C NL 950023 I2 NL950023 I2 NL 950023I2
Authority
NL
Netherlands
Prior art keywords
labeling
imaging agents
radionuclide
isonitrile complexes
radionuclide isonitrile
Prior art date
Application number
NL950023C
Other languages
English (en)
Other versions
NL950023I1 (nl
Original Assignee
Harvard College
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Harvard College filed Critical Harvard College
Publication of NL950023I1 publication Critical patent/NL950023I1/xx
Publication of NL950023I2 publication Critical patent/NL950023I2/nl

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/12—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by a special physical form, e.g. emulsion, microcapsules, liposomes, characterized by a special physical form, e.g. emulsions, dispersions, microcapsules
    • A61K51/1217—Dispersions, suspensions, colloids, emulsions, e.g. perfluorinated emulsion, sols
    • A61K51/1234—Liposomes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/025—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus inorganic Tc complexes or compounds
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C251/00—Compounds containing nitrogen atoms doubly-bound to a carbon skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F13/00—Compounds containing elements of Groups 7 or 17 of the Periodic Table
    • C07F13/005—Compounds without a metal-carbon linkage
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2123/00—Preparations for testing in vivo

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Optics & Photonics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Physics & Mathematics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Inorganic Chemistry (AREA)
  • Dispersion Chemistry (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicinal Preparation (AREA)
NL950023C 1982-04-30 1995-10-24 Radionuclide isonitrilcomplexen voor merkende en beeldvormende middelen. NL950023I2 (nl)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US06/373,511 US4452774A (en) 1982-04-30 1982-04-30 Isonitrile radionuclide complexes for labelling and imaging agents
DK257183A DK172154B1 (da) 1982-04-30 1983-06-06 Isonitrilkompleks omfattende et radionuclid, middel til anvendelse ved mærkning, afbildning eller detektering og indeholdende et sådant kompleks, kit til fremstilling af et sådant kompleks, og fremgangsmåde til mærkning af en celle eller et liposom in vitro

Publications (2)

Publication Number Publication Date
NL950023I1 NL950023I1 (nl) 1996-01-02
NL950023I2 true NL950023I2 (nl) 1997-12-01

Family

ID=39577807

Family Applications (1)

Application Number Title Priority Date Filing Date
NL950023C NL950023I2 (nl) 1982-04-30 1995-10-24 Radionuclide isonitrilcomplexen voor merkende en beeldvormende middelen.

Country Status (7)

Country Link
US (1) US4452774A (nl)
EP (1) EP0107734B1 (nl)
CA (1) CA1218666A (nl)
DE (1) DE3372709D1 (nl)
DK (1) DK172154B1 (nl)
NL (1) NL950023I2 (nl)
WO (1) WO1983003761A1 (nl)

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US4707544A (en) * 1984-11-28 1987-11-17 President And Fellows Of Harvard College Metal-isonitrile adducts for preparing radionuclide complexes for labelling and imaging agents
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US4872561A (en) * 1985-08-30 1989-10-10 Massachusetts Institute Of Technology Carboxy, carboalkoxy and carbamile substituted isonitrile radionuclide complexes
GB8531296D0 (en) * 1985-12-19 1986-01-29 Amersham Int Plc Cationic complexes of technetium
CA1305160C (en) * 1985-12-23 1992-07-14 Paul Louis Bergstein Ether isonitriles and radiolabeled complexes thereof
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US4971725A (en) * 1987-01-30 1990-11-20 Minnesota Mining And Manufacturing Company Thermochromic double-complex salts
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US5006329A (en) * 1988-01-22 1991-04-09 Cadema Medical Products, Inc. Radioactive tagged compounds and method for the treatment of metastatic bone cancer
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US5158760A (en) * 1990-05-30 1992-10-27 Board Of Regents, The University Of Texas System 99m TC labeled liposomes
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US5407653A (en) * 1991-06-26 1995-04-18 Brigham And Women's Hospital Evaluation of the multidrug resistance phenotype
US5210270A (en) * 1991-11-25 1993-05-11 Institute Of Nuclear Energy Research Method for synthesis and 99m C labelling of 2-alkoxyisobutylisonitrile
US5420321A (en) * 1993-08-03 1995-05-30 The Du Pont Merck Pharmaceutical Company Tris(isonitrile)copper(i) sulfates for preparing radionuclide complexes
CA2190727C (en) * 1994-05-19 2006-07-18 Sudhakar Kasina Aromatic amine substituted bridged nitrogen and sulfur donor atom ligands for imaging
US5961952A (en) * 1996-01-24 1999-10-05 Dupont Pharmaceuticals Company 99m Tc-tertiary-butyl isonitrile as breast tumor imaging agents
WO1997026922A1 (en) * 1996-01-24 1997-07-31 The Du Pont Merck Pharmaceutical Company 99mTc-TERTIARY-BUTYL ISONITRILE AND ANALOGS AS BREAST TUMOR IMAGING AGENTS
US5766952A (en) * 1996-07-25 1998-06-16 Regents Of The University Of Minnesota Vapochromic platinum-complexes and salts
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US6589503B1 (en) 1998-06-20 2003-07-08 Washington University Membrane-permeant peptide complexes for medical imaging, diagnostics, and pharmaceutical therapy
US7306784B2 (en) 1998-06-20 2007-12-11 Washington University Membrane-permeant peptide complexes for medical imaging, diagnostics, and pharmaceutical therapy
US8038984B2 (en) 1998-06-20 2011-10-18 Washington University Membrane-permeant peptide complexes for treatment of sepsis
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US6569402B1 (en) 1998-12-18 2003-05-27 Bristol-Myers Squibb Pharma Company Vitronectin receptor antagonist pharmaceuticals
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US6794518B1 (en) 1998-12-18 2004-09-21 Bristol-Myers Squibb Pharma Company Vitronectin receptor antagonist pharmaceuticals
US6511649B1 (en) 1998-12-18 2003-01-28 Thomas D. Harris Vitronectin receptor antagonist pharmaceuticals
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IL147629A0 (en) 2000-06-01 2002-08-14 Bristol Myers Squibb Pharma Co LACTAMS SUBSTITUTED BY CYCLIC SUCCINATES AS INHIBITORS OF Aβ PROTEIN PRODUCTION
CA2427911A1 (en) 2000-11-03 2002-05-10 Bristol Myers Squibb Company Simultaneous dual isotope imaging of cardiac perfusion and cardiac inflammation
CN1136921C (zh) * 2001-04-27 2004-02-04 北京师范大学 一种心肌显像剂及其制备方法
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JP5144497B2 (ja) * 2006-03-24 2013-02-13 富士フイルムＲｉファーマ株式会社 局所脳血流診断用放射性医薬品製造用組成物
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US4197312A (en) * 1978-05-09 1980-04-08 American Cyanamid Company Alkali metal and alkaline earth metal salts of benzoylacetonitriles
DE3060377D1 (en) * 1979-08-29 1982-07-01 Nihon Mediphysics Co Ltd 2-oxopropionaldehyde bis(thiosemicarbazone)derivatives and their production and use
US4363793A (en) * 1979-08-30 1982-12-14 State University Of New York Diagnostic radiopharmaceuticals for localization in target tissues exhibiting a regional pH shift relative to surrounding tissues

Also Published As

Publication number Publication date
WO1983003761A1 (en) 1983-11-10
DK257183A (da) 1984-12-07
DK257183D0 (da) 1983-06-06
EP0107734A4 (en) 1984-11-22
DK172154B1 (da) 1997-12-01
NL950023I1 (nl) 1996-01-02
EP0107734A1 (en) 1984-05-09
US4452774A (en) 1984-06-05
EP0107734B1 (en) 1987-07-29
CA1218666A (en) 1987-03-03
DE3372709D1 (en) 1987-09-03

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