NL7808142A - Nucleoside 1-methyl-iso:guanosine - isolated from marine sponges of genus Tedania and having muscle relaxant and CNS activity - Google Patents

Nucleoside 1-methyl-iso:guanosine - isolated from marine sponges of genus Tedania and having muscle relaxant and CNS activity

Info

Publication number
NL7808142A
NL7808142A NL7808142A NL7808142A NL7808142A NL 7808142 A NL7808142 A NL 7808142A NL 7808142 A NL7808142 A NL 7808142A NL 7808142 A NL7808142 A NL 7808142A NL 7808142 A NL7808142 A NL 7808142A
Authority
NL
Netherlands
Prior art keywords
methyl
tedania
guanosine
nucleoside
genus
Prior art date
Application number
NL7808142A
Other languages
Dutch (nl)
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US05/876,768 external-priority patent/US4148993A/en
Priority claimed from GB7826761A external-priority patent/GB2001955A/en
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Publication of NL7808142A publication Critical patent/NL7808142A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/16—Purine radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/052—Imidazole radicals

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Saccharide Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

1-methyl-isoguanosine (I) of the tautomeric formulae (Ia), (Ib) and (Ic), is new: (I) is a muscle relaxant and has effects on the CNS. It also has anti-inflammatory, antiallergic and hypotensive activity.
NL7808142A 1977-08-03 1978-08-02 Nucleoside 1-methyl-iso:guanosine - isolated from marine sponges of genus Tedania and having muscle relaxant and CNS activity NL7808142A (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
LU77910 1977-08-03
US05/876,768 US4148993A (en) 1978-02-10 1978-02-10 Process to produce 1-methyl isoguanosine
GB7826761A GB2001955A (en) 1977-08-03 1978-06-13 1-Methyl-isoguanine

Publications (1)

Publication Number Publication Date
NL7808142A true NL7808142A (en) 1979-02-06

Family

ID=27260557

Family Applications (1)

Application Number Title Priority Date Filing Date
NL7808142A NL7808142A (en) 1977-08-03 1978-08-02 Nucleoside 1-methyl-iso:guanosine - isolated from marine sponges of genus Tedania and having muscle relaxant and CNS activity

Country Status (1)

Country Link
NL (1) NL7808142A (en)

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Legal Events

Date Code Title Description
BV The patent application has lapsed