NL7805588A - 3,3,3-triarylalkyl-4-fenylalkyl-4-hydroxypiperidinen met geneeskrachtige activiteit. - Google Patents
3,3,3-triarylalkyl-4-fenylalkyl-4-hydroxypiperidinen met geneeskrachtige activiteit.Info
- Publication number
- NL7805588A NL7805588A NL7805588A NL7805588A NL7805588A NL 7805588 A NL7805588 A NL 7805588A NL 7805588 A NL7805588 A NL 7805588A NL 7805588 A NL7805588 A NL 7805588A NL 7805588 A NL7805588 A NL 7805588A
- Authority
- NL
- Netherlands
- Prior art keywords
- hydroxypiperidins
- triarylalkyl
- phenylalkyl
- medicinal activity
- medicinal
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C07D491/10—Spiro-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D211/40—Oxygen atoms
- C07D211/44—Oxygen atoms attached in position 4
- C07D211/48—Oxygen atoms attached in position 4 having an acyclic carbon atom attached in position 4
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US05/799,864 US4116963A (en) | 1977-05-23 | 1977-05-23 | 3,3,3-triarylalkyl-4-phenylalkyl-4-hydroxy piperidines and related compounds |
Publications (1)
Publication Number | Publication Date |
---|---|
NL7805588A true NL7805588A (nl) | 1978-11-27 |
Family
ID=25176958
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
NL7805588A NL7805588A (nl) | 1977-05-23 | 1978-05-23 | 3,3,3-triarylalkyl-4-fenylalkyl-4-hydroxypiperidinen met geneeskrachtige activiteit. |
Country Status (8)
Country | Link |
---|---|
US (1) | US4116963A (fr) |
JP (1) | JPS53149981A (fr) |
AU (1) | AU514452B2 (fr) |
CA (1) | CA1105466A (fr) |
DE (1) | DE2822307A1 (fr) |
FR (1) | FR2392007A1 (fr) |
GB (1) | GB1570271A (fr) |
NL (1) | NL7805588A (fr) |
Families Citing this family (20)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE2930449A1 (de) * | 1979-07-26 | 1981-02-19 | Bayer Ag | N-acyl-piperidonketale, verfahren zu deren herstellung und deren verwendung als gegenmittel zum schutz von kulturpflanzen vor schaedigungen durch herbizide |
US4333942A (en) * | 1979-08-03 | 1982-06-08 | Byk Gulden Lomberg Chemische Fabrik Gmbh | Anti-depressant and analgesic 4-phenoxypiperidines |
US4330546A (en) * | 1979-09-14 | 1982-05-18 | John Wyeth & Brother Limited | 3-Aryl-3-aryloxypropylamines |
GB8806224D0 (en) * | 1988-03-16 | 1988-04-13 | Johnson Matthey Plc | Platinum chemotherapeutic product |
US6190691B1 (en) | 1994-04-12 | 2001-02-20 | Adolor Corporation | Methods for treating inflammatory conditions |
US5962477A (en) * | 1994-04-12 | 1999-10-05 | Adolor Corporation | Screening methods for cytokine inhibitors |
US6573282B1 (en) | 1995-09-12 | 2003-06-03 | Adolor Corporation | Peripherally active anti-hyperalgesic opiates |
US5849761A (en) * | 1995-09-12 | 1998-12-15 | Regents Of The University Of California | Peripherally active anti-hyperalgesic opiates |
US6353004B1 (en) | 1997-07-14 | 2002-03-05 | Adolor Coporation | Peripherally acting anti-pruritic opiates |
US5849762A (en) * | 1997-07-14 | 1998-12-15 | Adolor Corporation | Peripherally acting anti-pruritic opiates |
SI1615646T2 (sl) | 2003-04-08 | 2022-11-30 | Progenics Pharmaceuticals, Inc. | Farmacevtske formulacije vsebujoče metilnatrekson |
AR057325A1 (es) | 2005-05-25 | 2007-11-28 | Progenics Pharm Inc | Sintesis de (s)-n-metilnaltrexona, composiciones farmaceuticas y usos |
AR057035A1 (es) | 2005-05-25 | 2007-11-14 | Progenics Pharm Inc | SíNTESIS DE (R)-N-METILNALTREXONA, COMPOSICIONES FARMACÉUTICAS Y USOS |
EP1749528A1 (fr) | 2005-08-05 | 2007-02-07 | Pharma C S.A. | Combinaisons pharmaceutiques comprenant un agoniste de l'opioide mu et un inhibiteur de la production de monoxide d'azote |
JP2009507800A (ja) * | 2005-09-09 | 2009-02-26 | ユーロ−セルティーク エス.エイ. | 縮合およびスピロ環化合物ならびにその使用 |
BRPI0809579B8 (pt) | 2007-03-29 | 2021-05-25 | Progenics Pharm Inc | formas cristalinas e seus usos |
DK2565195T3 (en) | 2007-03-29 | 2015-06-29 | Wyeth Llc | PERIPHERAL OPIOID RECEPTOR AND ANTAGONISTS AND USES THEREOF |
EP2137191B8 (fr) | 2007-03-29 | 2016-06-08 | Progenics Pharmaceuticals, Inc. | Antagonistes de récepteurs opioïdes périphériques, et leurs utilisations |
AU2008349873B2 (en) | 2008-02-06 | 2014-02-13 | Progenics Pharmaceuticals, Inc. | Preparation and use of (R),(R)-2,2'-bis-methylnaltrexone |
CA2676881C (fr) | 2008-09-30 | 2017-04-25 | Wyeth | Antagonistes de recepteurs opioides peripheriques, et leurs utilisations |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB895309A (en) * | 1959-11-18 | 1962-05-02 | Res Lab Dr C Janssen Nv | Pyrrolidine and piperidine derivatives |
GB963639A (en) * | 1960-10-20 | 1964-07-15 | Arnold Heyworth Beckett | New piperidine derivatives and processes for preparing the same |
SE307788B (fr) * | 1965-04-23 | 1969-01-20 | Yoshitomi Pharmaceutical | |
JPS5755714B2 (fr) * | 1972-03-18 | 1982-11-25 | ||
US3998832A (en) * | 1975-04-16 | 1976-12-21 | G. D. Searle & Co. | Anti-diarrheal compounds |
-
1977
- 1977-05-23 US US05/799,864 patent/US4116963A/en not_active Expired - Lifetime
-
1978
- 1978-05-22 AU AU36352/78A patent/AU514452B2/en not_active Expired
- 1978-05-22 DE DE19782822307 patent/DE2822307A1/de not_active Withdrawn
- 1978-05-22 GB GB21130/78A patent/GB1570271A/en not_active Expired
- 1978-05-23 NL NL7805588A patent/NL7805588A/xx not_active Application Discontinuation
- 1978-05-23 CA CA303,828A patent/CA1105466A/fr not_active Expired
- 1978-05-23 JP JP6152578A patent/JPS53149981A/ja active Pending
- 1978-05-23 FR FR7815310A patent/FR2392007A1/fr active Granted
Also Published As
Publication number | Publication date |
---|---|
JPS53149981A (en) | 1978-12-27 |
FR2392007B1 (fr) | 1982-10-08 |
AU514452B2 (en) | 1981-02-12 |
GB1570271A (en) | 1980-06-25 |
US4116963A (en) | 1978-09-26 |
CA1105466A (fr) | 1981-07-21 |
FR2392007A1 (fr) | 1978-12-22 |
AU3635278A (en) | 1979-11-29 |
DE2822307A1 (de) | 1978-12-21 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
BV | The patent application has lapsed |