FR2392007B1 - - Google Patents

Info

Publication number
FR2392007B1
FR2392007B1 FR7815310A FR7815310A FR2392007B1 FR 2392007 B1 FR2392007 B1 FR 2392007B1 FR 7815310 A FR7815310 A FR 7815310A FR 7815310 A FR7815310 A FR 7815310A FR 2392007 B1 FR2392007 B1 FR 2392007B1
Authority
FR
France
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
FR7815310A
Other versions
FR2392007A1 (fr
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
GD Searle LLC
Original Assignee
GD Searle LLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by GD Searle LLC filed Critical GD Searle LLC
Publication of FR2392007A1 publication Critical patent/FR2392007A1/fr
Application granted granted Critical
Publication of FR2392007B1 publication Critical patent/FR2392007B1/fr
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/10—Spiro-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D211/40—Oxygen atoms
    • C07D211/44—Oxygen atoms attached in position 4
    • C07D211/48—Oxygen atoms attached in position 4 having an acyclic carbon atom attached in position 4
FR7815310A 1977-05-23 1978-05-23 3,3,3-triarylalkyl-4-phenylalkyl-4-hydroxy-piperidines, leurs derives, leur preparation et leur utilisation comme antidiarrheiques et analgesiques Granted FR2392007A1 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US05/799,864 US4116963A (en) 1977-05-23 1977-05-23 3,3,3-triarylalkyl-4-phenylalkyl-4-hydroxy piperidines and related compounds

Publications (2)

Publication Number Publication Date
FR2392007A1 FR2392007A1 (fr) 1978-12-22
FR2392007B1 true FR2392007B1 (fr) 1982-10-08

Family

ID=25176958

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7815310A Granted FR2392007A1 (fr) 1977-05-23 1978-05-23 3,3,3-triarylalkyl-4-phenylalkyl-4-hydroxy-piperidines, leurs derives, leur preparation et leur utilisation comme antidiarrheiques et analgesiques

Country Status (8)

Country Link
US (1) US4116963A (fr)
JP (1) JPS53149981A (fr)
AU (1) AU514452B2 (fr)
CA (1) CA1105466A (fr)
DE (1) DE2822307A1 (fr)
FR (1) FR2392007A1 (fr)
GB (1) GB1570271A (fr)
NL (1) NL7805588A (fr)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2930449A1 (de) * 1979-07-26 1981-02-19 Bayer Ag N-acyl-piperidonketale, verfahren zu deren herstellung und deren verwendung als gegenmittel zum schutz von kulturpflanzen vor schaedigungen durch herbizide
US4333942A (en) * 1979-08-03 1982-06-08 Byk Gulden Lomberg Chemische Fabrik Gmbh Anti-depressant and analgesic 4-phenoxypiperidines
US4325953A (en) * 1979-09-14 1982-04-20 John Wyeth And Brother Limited 4-Aryl-4-aryloxypiperidines
GB8806224D0 (en) * 1988-03-16 1988-04-13 Johnson Matthey Plc Platinum chemotherapeutic product
US5962477A (en) * 1994-04-12 1999-10-05 Adolor Corporation Screening methods for cytokine inhibitors
US6190691B1 (en) 1994-04-12 2001-02-20 Adolor Corporation Methods for treating inflammatory conditions
US5849761A (en) 1995-09-12 1998-12-15 Regents Of The University Of California Peripherally active anti-hyperalgesic opiates
US6573282B1 (en) 1995-09-12 2003-06-03 Adolor Corporation Peripherally active anti-hyperalgesic opiates
US6353004B1 (en) 1997-07-14 2002-03-05 Adolor Coporation Peripherally acting anti-pruritic opiates
US5849762A (en) * 1997-07-14 1998-12-15 Adolor Corporation Peripherally acting anti-pruritic opiates
US20040266806A1 (en) 2003-04-08 2004-12-30 Sanghvi Suketu P. Pharmaceutical formulation
AR057035A1 (es) 2005-05-25 2007-11-14 Progenics Pharm Inc SíNTESIS DE (R)-N-METILNALTREXONA, COMPOSICIONES FARMACÉUTICAS Y USOS
AR057325A1 (es) 2005-05-25 2007-11-28 Progenics Pharm Inc Sintesis de (s)-n-metilnaltrexona, composiciones farmaceuticas y usos
EP1749528A1 (fr) 2005-08-05 2007-02-07 Pharma C S.A. Combinaisons pharmaceutiques comprenant un agoniste de l'opioide mu et un inhibiteur de la production de monoxide d'azote
WO2007028638A1 (fr) 2005-09-09 2007-03-15 Euro-Celtique S.A. Composes fondus et spirocycle ainsi que l'utilisation de ceux-ci
EP3064503A1 (fr) 2007-03-29 2016-09-07 Progenics Pharmaceuticals, Inc. Antagonistes des récepteurs opioïdes périphériques et leur utilisation
WO2008121352A2 (fr) 2007-03-29 2008-10-09 Progenics Pharmaceuticals, Inc. Formes cristallines, et leurs utilisations
DK2565195T3 (en) 2007-03-29 2015-06-29 Wyeth Llc PERIPHERAL OPIOID RECEPTOR AND ANTAGONISTS AND USES THEREOF
CN101959892B (zh) 2008-02-06 2014-01-08 普罗热尼奇制药公司 (r),(r)-2,2’-二-甲基纳曲酮的制备和用途
CA2676881C (fr) 2008-09-30 2017-04-25 Wyeth Antagonistes de recepteurs opioides peripheriques, et leurs utilisations

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB895309A (en) * 1959-11-18 1962-05-02 Res Lab Dr C Janssen Nv Pyrrolidine and piperidine derivatives
GB963639A (en) * 1960-10-20 1964-07-15 Arnold Heyworth Beckett New piperidine derivatives and processes for preparing the same
SE307788B (fr) * 1965-04-23 1969-01-20 Yoshitomi Pharmaceutical
JPS5755714B2 (fr) * 1972-03-18 1982-11-25
US3998832A (en) * 1975-04-16 1976-12-21 G. D. Searle & Co. Anti-diarrheal compounds

Also Published As

Publication number Publication date
DE2822307A1 (de) 1978-12-21
FR2392007A1 (fr) 1978-12-22
JPS53149981A (en) 1978-12-27
CA1105466A (fr) 1981-07-21
AU3635278A (en) 1979-11-29
NL7805588A (nl) 1978-11-27
US4116963A (en) 1978-09-26
GB1570271A (en) 1980-06-25
AU514452B2 (en) 1981-02-12

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Legal Events

Date Code Title Description
ST Notification of lapse