NL7704030A - Werkwijze ter bereiding van bis-quartaire pyridinium-2-aldoxime-zouten. - Google Patents
Werkwijze ter bereiding van bis-quartaire pyridinium-2-aldoxime-zouten.Info
- Publication number
- NL7704030A NL7704030A NL7704030A NL7704030A NL7704030A NL 7704030 A NL7704030 A NL 7704030A NL 7704030 A NL7704030 A NL 7704030A NL 7704030 A NL7704030 A NL 7704030A NL 7704030 A NL7704030 A NL 7704030A
- Authority
- NL
- Netherlands
- Prior art keywords
- pyridinium
- quarter
- preparing bis
- aldoxime
- salts
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D213/44—Radicals substituted by doubly-bound oxygen, sulfur, or nitrogen atoms, or by two such atoms singly-bound to the same carbon atom
- C07D213/53—Nitrogen atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P39/00—General protective or antinoxious agents
- A61P39/02—Antidotes
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D213/79—Acids; Esters
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D213/81—Amides; Imides
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE19762616481 DE2616481A1 (de) | 1976-04-14 | 1976-04-14 | Bis-quartaere pyridinium-2-aldoxim- salze und verfahren zu ihrer herstellung |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| NL7704030A true NL7704030A (nl) | 1977-10-18 |
Family
ID=5975404
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NL7704030A NL7704030A (nl) | 1976-04-14 | 1977-04-13 | Werkwijze ter bereiding van bis-quartaire pyridinium-2-aldoxime-zouten. |
Country Status (16)
| Country | Link |
|---|---|
| US (1) | US4128651A (nl) |
| JP (1) | JPS52128381A (nl) |
| AT (1) | AT361923B (nl) |
| BE (1) | BE853570A (nl) |
| CA (1) | CA1070307A (nl) |
| CH (1) | CH627745A5 (nl) |
| DE (1) | DE2616481A1 (nl) |
| DK (1) | DK163177A (nl) |
| ES (1) | ES457791A1 (nl) |
| FR (1) | FR2348211A1 (nl) |
| GB (1) | GB1516626A (nl) |
| IE (1) | IE44737B1 (nl) |
| IL (1) | IL51857A (nl) |
| NL (1) | NL7704030A (nl) |
| SE (1) | SE7704240L (nl) |
| ZA (1) | ZA772253B (nl) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4352810A (en) | 1979-07-26 | 1982-10-05 | Nederlandse Centrale Organisatie Voor Toegepast-Natuurwetenschappelijkond erzoek | 1-Substituted hydroxyiminomethyl-pyridinium salts, with an activity against organophosphate poisonings |
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AT365410B (de) * | 1978-08-31 | 1982-01-11 | Ciba Geigy Ag | Mittel zum schutz von kulturpflanzen vor aggressi-ven herbiziden |
| DE3332272A1 (de) * | 1983-09-07 | 1985-03-21 | Bayer Ag, 5090 Leverkusen | Herbizide mittel enthaltend metribuzin in kombination mit pyridincarbonsaeureamiden |
| IL72788A (en) * | 1984-08-28 | 1989-07-31 | Israel State | Bis quaternary oxy-bis methylene(or trimethylene)bis-n-quinuclidines,pyridines and piperidines,their preparation and antidotes against organophosphorus and carbamate poisoning containing them |
| US5130438A (en) * | 1985-11-20 | 1992-07-14 | The United States Of America As Represented By The Secretary Of The Army | Bis-methylene ether pyridinium compound preparation |
| US5760049A (en) * | 1997-02-21 | 1998-06-02 | Synapse Pharmaceuticals International, Inc. | Method for controlling tobacco use and alleviating withdrawal symptoms due to cessation of tobacco use |
| US7414135B2 (en) * | 2005-02-17 | 2008-08-19 | Aerojet Fine Chemicals Llc | Process for halomethyl ethers of hydroxyiminomethyl quaternary pyridinium salts |
| US20060247281A1 (en) * | 2005-02-17 | 2006-11-02 | Aerojet Fine Chemicals Llc, A Delaware Limited Liability Company | Process for halomethyl ethers of hydroxyiminomethyl quaternary pyridinium salts |
| US8946200B2 (en) * | 2006-11-02 | 2015-02-03 | Southwest Research Institute | Pharmaceutically active nanosuspensions |
| US8404850B2 (en) * | 2008-03-13 | 2013-03-26 | Southwest Research Institute | Bis-quaternary pyridinium-aldoxime salts and treatment of exposure to cholinesterase inhibitors |
| US8722706B2 (en) * | 2008-08-15 | 2014-05-13 | Southwest Research Institute | Two phase bioactive formulations of bis-quaternary pyridinium oxime sulfonate salts |
| US8309134B2 (en) * | 2008-10-03 | 2012-11-13 | Southwest Research Institute | Modified calcium phosphate nanoparticle formation |
| US9028873B2 (en) * | 2010-02-08 | 2015-05-12 | Southwest Research Institute | Nanoparticles for drug delivery to the central nervous system |
| WO2011142826A1 (en) * | 2010-05-12 | 2011-11-17 | Mississipi State University | Phenoxyalkyl pyridinium oxime therapeutics for treatment of organophosphate poisoning |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3773775A (en) * | 1968-08-27 | 1973-11-20 | Merck Patent Gmbh | Bis-quaternary pyridinium salts |
-
1976
- 1976-04-14 DE DE19762616481 patent/DE2616481A1/de not_active Withdrawn
-
1977
- 1977-04-08 FR FR7710729A patent/FR2348211A1/fr active Granted
- 1977-04-11 IL IL51857A patent/IL51857A/xx unknown
- 1977-04-11 US US05/786,693 patent/US4128651A/en not_active Expired - Lifetime
- 1977-04-13 CA CA276,042A patent/CA1070307A/en not_active Expired
- 1977-04-13 GB GB15341/77A patent/GB1516626A/en not_active Expired
- 1977-04-13 ZA ZA00772253A patent/ZA772253B/xx unknown
- 1977-04-13 CH CH459277A patent/CH627745A5/de not_active IP Right Cessation
- 1977-04-13 DK DK163177A patent/DK163177A/da not_active IP Right Cessation
- 1977-04-13 NL NL7704030A patent/NL7704030A/nl not_active Application Discontinuation
- 1977-04-13 IE IE759/77A patent/IE44737B1/en unknown
- 1977-04-13 AT AT257077A patent/AT361923B/de not_active IP Right Cessation
- 1977-04-13 SE SE7704240A patent/SE7704240L/xx not_active Application Discontinuation
- 1977-04-14 BE BE2055827A patent/BE853570A/xx unknown
- 1977-04-14 JP JP4342577A patent/JPS52128381A/ja active Pending
- 1977-04-14 ES ES457791A patent/ES457791A1/es not_active Expired
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4352810A (en) | 1979-07-26 | 1982-10-05 | Nederlandse Centrale Organisatie Voor Toegepast-Natuurwetenschappelijkond erzoek | 1-Substituted hydroxyiminomethyl-pyridinium salts, with an activity against organophosphate poisonings |
Also Published As
| Publication number | Publication date |
|---|---|
| CA1070307A (en) | 1980-01-22 |
| IL51857A0 (en) | 1977-06-30 |
| CH627745A5 (de) | 1982-01-29 |
| AT361923B (de) | 1981-04-10 |
| US4128651A (en) | 1978-12-05 |
| ES457791A1 (es) | 1978-08-01 |
| GB1516626A (en) | 1978-07-05 |
| SE7704240L (sv) | 1977-10-15 |
| IE44737L (en) | 1977-10-14 |
| DE2616481A1 (de) | 1977-11-03 |
| FR2348211A1 (fr) | 1977-11-10 |
| IE44737B1 (en) | 1982-03-10 |
| ZA772253B (en) | 1978-03-29 |
| BE853570A (fr) | 1977-10-14 |
| JPS52128381A (en) | 1977-10-27 |
| IL51857A (en) | 1980-05-30 |
| DK163177A (da) | 1977-10-15 |
| FR2348211B1 (nl) | 1980-04-18 |
| ATA257077A (de) | 1980-09-15 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| NL7703515A (nl) | Werkwijze ter bereiding van triazolopyrimidinen. | |
| NL7709107A (nl) | Werkwijze ter bereiding van polyurethanurea. | |
| NL162925B (nl) | Werkwijze ter bereiding van alpha-alkeenpolymeren. | |
| NL7706948A (nl) | Werkwijze ter bereiding van muramyldipeptide- -derivaten. | |
| NL7707467A (nl) | Werkwijze ter bereiding van hexahydrodibenzo- pyranonverbindingen. | |
| NL7702726A (nl) | Werkwijze ter bereiding van xylitol. | |
| NL7704121A (nl) | Werkwijze ter bereiding van polyetherimiden. | |
| NL7710678A (nl) | Werkwijze ter bereiding van arylsulfoniumzouten. | |
| NL7707128A (nl) | Werkwijze ter bereiding van 4-hydrocyfenyl- alkanolaminederivaten. | |
| NL188748C (nl) | Werkwijze ter bereiding van isobuteen. | |
| NL7701128A (nl) | Werkwijze ter bereiding van meta-aryloxy- -benzaldehyden. | |
| NL7702169A (nl) | Werkwijze ter bereiding van poly-n-butenen. | |
| NL186692C (nl) | Werkwijze ter bereiding van pent-3-eenzuur. | |
| NL7704030A (nl) | Werkwijze ter bereiding van bis-quartaire pyridinium-2-aldoxime-zouten. | |
| NL7707399A (nl) | Werkwijze ter bereiding van alkeenpolymeren. | |
| NL7707200A (nl) | Werkwijze ter bereiding van cyclopentaanderi- vaten. | |
| NL189521C (nl) | Werkwijze ter bereiding van ubichinon-10. | |
| NL7711931A (nl) | Werkwijze ter bereiding van glycerine. | |
| NL7703541A (nl) | Werkwijze ter bereiding van uracilverbindingen. | |
| NL7705927A (nl) | Werkwijze ter bereiding van aldehyden. | |
| NL7704602A (nl) | Werkwijze ter bereiding van 1,4-dicyanobutenen. | |
| NL7709238A (nl) | Werkwijze ter bereiding van gesubstitueerde benzimidazolen. | |
| NL7712163A (nl) | Werkwijze ter bereiding van 3-acylaminoazetidine 2-onen. | |
| NL187630C (nl) | Werkwijze ter bereiding van benzazocinederivaten. | |
| NL7712841A (nl) | Werkwijze ter bereiding van fenylalkylcarbon- zuren. |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| BV | The patent application has lapsed |