NL7507554A - Allopurinol prodn in high yield - by reacting ethoxymethylenecyanoethyl acetate with hydrazine then with formamide - Google Patents
Allopurinol prodn in high yield - by reacting ethoxymethylenecyanoethyl acetate with hydrazine then with formamideInfo
- Publication number
- NL7507554A NL7507554A NL7507554A NL7507554A NL7507554A NL 7507554 A NL7507554 A NL 7507554A NL 7507554 A NL7507554 A NL 7507554A NL 7507554 A NL7507554 A NL 7507554A NL 7507554 A NL7507554 A NL 7507554A
- Authority
- NL
- Netherlands
- Prior art keywords
- acetate
- ethoxymethylenecyanoethyl
- formamide
- hydrazine
- reacting
- Prior art date
Links
- ZHNUHDYFZUAESO-UHFFFAOYSA-N Formamide Chemical compound NC=O ZHNUHDYFZUAESO-UHFFFAOYSA-N 0.000 title abstract 4
- OAKJQQAXSVQMHS-UHFFFAOYSA-N Hydrazine Chemical compound NN OAKJQQAXSVQMHS-UHFFFAOYSA-N 0.000 title abstract 4
- VAQCKCSLIKYOKA-UHFFFAOYSA-N (2-cyano-3-ethoxyprop-2-enyl) acetate Chemical compound C(C)(=O)OCC(C#N)=COCC VAQCKCSLIKYOKA-UHFFFAOYSA-N 0.000 title abstract 3
- OFCNXPDARWKPPY-UHFFFAOYSA-N allopurinol Chemical compound OC1=NC=NC2=C1C=NN2 OFCNXPDARWKPPY-UHFFFAOYSA-N 0.000 title 1
- 229960003459 allopurinol Drugs 0.000 title 1
- LWNYFZDKJGYYLI-UHFFFAOYSA-N (2-cyano-3-hydrazinylprop-2-enyl) acetate Chemical compound C(C)(=O)OCC(C#N)=CNN LWNYFZDKJGYYLI-UHFFFAOYSA-N 0.000 abstract 1
- KAUABWYBFARJAF-UHFFFAOYSA-N 1h-pyrazol-4-ol Chemical compound OC=1C=NNC=1 KAUABWYBFARJAF-UHFFFAOYSA-N 0.000 abstract 1
- CZPWVGJYEJSRLH-UHFFFAOYSA-N Pyrimidine Chemical compound C1=CN=CN=C1 CZPWVGJYEJSRLH-UHFFFAOYSA-N 0.000 abstract 1
- 239000003960 organic solvent Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C255/00—Carboxylic acid nitriles
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DK378674A DK133432B (da) | 1974-07-15 | 1974-07-15 | Fremgangsmåde til fremstilling af allopurinol. |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| NL7507554A true NL7507554A (en) | 1976-01-19 |
Family
ID=8126758
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NL7507554A NL7507554A (en) | 1974-07-15 | 1975-06-25 | Allopurinol prodn in high yield - by reacting ethoxymethylenecyanoethyl acetate with hydrazine then with formamide |
Country Status (3)
| Country | Link |
|---|---|
| JP (1) | JPS518290A (enExample) |
| DK (1) | DK133432B (enExample) |
| NL (1) | NL7507554A (enExample) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102643279A (zh) * | 2012-02-09 | 2012-08-22 | 临海市恒源化工有限公司 | 一种别嘌醇的合成方法 |
-
1974
- 1974-07-15 DK DK378674A patent/DK133432B/da not_active IP Right Cessation
-
1975
- 1975-01-28 JP JP1105375A patent/JPS518290A/ja active Pending
- 1975-06-25 NL NL7507554A patent/NL7507554A/xx not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| JPS518290A (ja) | 1976-01-23 |
| DK378674A (enExample) | 1976-01-16 |
| DK133432C (enExample) | 1976-10-11 |
| DK133432B (da) | 1976-05-17 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| BV | The patent application has lapsed |