NL7504570A - Thienyl- en thietylverbindingen met bloeddruk- verlagende activiteit. - Google Patents

Thienyl- en thietylverbindingen met bloeddruk- verlagende activiteit.

Info

Publication number
NL7504570A
NL7504570A NL7504570A NL7504570A NL7504570A NL 7504570 A NL7504570 A NL 7504570A NL 7504570 A NL7504570 A NL 7504570A NL 7504570 A NL7504570 A NL 7504570A NL 7504570 A NL7504570 A NL 7504570A
Authority
NL
Netherlands
Prior art keywords
thietyl
thienyl
compounds
blood pressure
pressure reducing
Prior art date
Application number
NL7504570A
Other languages
English (en)
Dutch (nl)
Original Assignee
Du Pont
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Du Pont filed Critical Du Pont
Publication of NL7504570A publication Critical patent/NL7504570A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D331/00—Heterocyclic compounds containing rings of less than five members, having one sulfur atom as the only ring hetero atom
    • C07D331/04—Four-membered rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
    • C07D333/46—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings substituted on the ring sulfur atom
    • C07D333/48—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings substituted on the ring sulfur atom by oxygen atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
NL7504570A 1974-04-17 1975-04-17 Thienyl- en thietylverbindingen met bloeddruk- verlagende activiteit. NL7504570A (nl)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US46169974A 1974-04-17 1974-04-17
US05/555,307 US4009847A (en) 1974-04-17 1975-03-11 1-Tertiary-alkyl-3-(substituted thienyl)ureas and 1-tertiary-alkyl-3-(substituted thietyl)ureas as antihypertensive agents

Publications (1)

Publication Number Publication Date
NL7504570A true NL7504570A (nl) 1975-10-21

Family

ID=27040095

Family Applications (1)

Application Number Title Priority Date Filing Date
NL7504570A NL7504570A (nl) 1974-04-17 1975-04-17 Thienyl- en thietylverbindingen met bloeddruk- verlagende activiteit.

Country Status (21)

Country Link
US (1) US4009847A (enExample)
JP (1) JPS50148349A (enExample)
AR (1) AR208545A1 (enExample)
CA (1) CA1047042A (enExample)
CH (1) CH611292A5 (enExample)
DD (1) DD117223A5 (enExample)
DE (1) DE2516554A1 (enExample)
DK (1) DK164175A (enExample)
ES (1) ES436648A1 (enExample)
FI (1) FI751128A7 (enExample)
FR (1) FR2267773B1 (enExample)
GB (1) GB1461209A (enExample)
HU (1) HU173052B (enExample)
IE (1) IE41143B1 (enExample)
IL (1) IL47095A (enExample)
LU (1) LU72306A1 (enExample)
NL (1) NL7504570A (enExample)
NO (1) NO144071C (enExample)
PH (1) PH11722A (enExample)
SE (1) SE417965B (enExample)
YU (1) YU96075A (enExample)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4156738A (en) * 1977-10-07 1979-05-29 E. I. Du Pont De Nemours And Company Ureidonitriles useful as antihypertensives
US6187799B1 (en) * 1997-05-23 2001-02-13 Onyx Pharmaceuticals Inhibition of raf kinase activity using aryl ureas
US6344476B1 (en) * 1997-05-23 2002-02-05 Bayer Corporation Inhibition of p38 kinase activity by aryl ureas
US7517880B2 (en) * 1997-12-22 2009-04-14 Bayer Pharmaceuticals Corporation Inhibition of p38 kinase using symmetrical and unsymmetrical diphenyl ureas
US20080300281A1 (en) * 1997-12-22 2008-12-04 Jacques Dumas Inhibition of p38 Kinase Activity Using Aryl and Heteroaryl Substituted Heterocyclic Ureas
US7329670B1 (en) * 1997-12-22 2008-02-12 Bayer Pharmaceuticals Corporation Inhibition of RAF kinase using aryl and heteroaryl substituted heterocyclic ureas
US20080269265A1 (en) * 1998-12-22 2008-10-30 Scott Miller Inhibition Of Raf Kinase Using Symmetrical And Unsymmetrical Substituted Diphenyl Ureas
US7928239B2 (en) 1999-01-13 2011-04-19 Bayer Healthcare Llc Inhibition of RAF kinase using quinolyl, isoquinolyl or pyridyl ureas
JP2002534468A (ja) * 1999-01-13 2002-10-15 バイエル コーポレイション ｐ３８キナーゼ阻害剤としてのω−カルボキシアリール置換ジフェニル尿素
US7351834B1 (en) * 1999-01-13 2008-04-01 Bayer Pharmaceuticals Corporation ω-Carboxyaryl substituted diphenyl ureas as raf kinase inhibitors
WO2000042012A1 (en) 1999-01-13 2000-07-20 Bayer Corporation φ-CARBOXYARYL SUBSTITUTED DIPHENYL UREAS AS RAF KINASE INHIBITORS
US8124630B2 (en) * 1999-01-13 2012-02-28 Bayer Healthcare Llc ω-carboxyaryl substituted diphenyl ureas as raf kinase inhibitors
US7235576B1 (en) 2001-01-12 2007-06-26 Bayer Pharmaceuticals Corporation Omega-carboxyaryl substituted diphenyl ureas as raf kinase inhibitors
US7371763B2 (en) * 2001-04-20 2008-05-13 Bayer Pharmaceuticals Corporation Inhibition of raf kinase using quinolyl, isoquinolyl or pyridyl ureas
EP1450799B2 (en) * 2001-12-03 2018-07-11 Bayer HealthCare LLC Aryl urea compounds in combination with other cytostatic or cytotoxic agents for treating human cancers
US20080108672A1 (en) * 2002-01-11 2008-05-08 Bernd Riedl Omega-Carboxyaryl Substituted Diphenyl Ureas As Raf Kinase Inhibitors
US20040023961A1 (en) * 2002-02-11 2004-02-05 Bayer Corporation Aryl ureas with raf kinase and angiogenisis inhibiting activity
CN1318404C (zh) * 2002-02-11 2007-05-30 拜耳制药公司 作为激酶抑制剂的芳基脲类化合物
US20030216396A1 (en) * 2002-02-11 2003-11-20 Bayer Corporation Pyridine, quinoline, and isoquinoline N-oxides as kinase inhibitors
DK1478358T3 (da) 2002-02-11 2013-10-07 Bayer Healthcare Llc Sorafenibtosylat til behandling af sygdomme kendetegnet ved unormal angiogenese
UY28213A1 (es) 2003-02-28 2004-09-30 Bayer Pharmaceuticals Corp Nuevos derivados de cianopiridina útiles en el tratamiento de cáncer y otros trastornos.
DE602004011340T2 (de) * 2003-05-20 2008-11-06 Bayer Healthcare Llc Diaryl-harnstoffe mit kinasehemmender wirkung
JP4777887B2 (ja) * 2003-07-23 2011-09-21 バイエル、ファーマシューテイカルズ、コーポレイション 病気および状態の処置および防止のためのフロロ置換オメガカルボキシアリールジフェニル尿素
WO2005110994A2 (en) * 2004-04-30 2005-11-24 Bayer Pharmaceuticals Corporation Substituted pyrazolyl urea derivatives useful in the treatment of cancer

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH452475A (de) * 1965-05-20 1968-05-31 Bayer Ag Verfahren zum Färben und Bedrucken von synthetischem Textilmaterial mit Anthrachinonfarbstoffen

Also Published As

Publication number Publication date
FI751128A7 (enExample) 1975-10-18
CA1047042A (en) 1979-01-23
GB1461209A (en) 1977-01-13
JPS50148349A (enExample) 1975-11-27
CH611292A5 (enExample) 1979-05-31
IE41143B1 (en) 1979-10-24
SE7503523L (sv) 1975-10-20
NO144071C (no) 1981-06-17
DD117223A5 (enExample) 1976-01-05
LU72306A1 (enExample) 1976-03-17
ES436648A1 (es) 1977-08-01
SE417965B (sv) 1981-04-27
HU173052B (hu) 1979-02-28
FR2267773A1 (enExample) 1975-11-14
YU96075A (en) 1983-04-27
FR2267773B1 (enExample) 1978-08-18
PH11722A (en) 1978-05-30
DE2516554A1 (de) 1975-10-30
IL47095A (en) 1978-03-10
IE41143L (en) 1975-10-17
NO751351L (enExample) 1975-10-20
DK164175A (da) 1975-10-18
AR208545A1 (es) 1977-02-15
AU8013575A (en) 1976-10-21
NO144071B (no) 1981-03-09
US4009847A (en) 1977-03-01
IL47095A0 (en) 1975-06-25

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Legal Events

Date Code Title Description
BV The patent application has lapsed