NL7102324A - - Google Patents

Info

Publication number
NL7102324A
NL7102324A NL7102324A NL7102324A NL7102324A NL 7102324 A NL7102324 A NL 7102324A NL 7102324 A NL7102324 A NL 7102324A NL 7102324 A NL7102324 A NL 7102324A NL 7102324 A NL7102324 A NL 7102324A
Authority
NL
Netherlands
Application number
NL7102324A
Other versions
NL171446B (nl
NL171446C (nl
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed filed Critical
Publication of NL7102324A publication Critical patent/NL7102324A/xx
Publication of NL171446B publication Critical patent/NL171446B/xx
Application granted granted Critical
Publication of NL171446C publication Critical patent/NL171446C/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C255/00Carboxylic acid nitriles
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/61Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
    • C07C45/67Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton
    • C07C45/68Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms
    • C07C45/70Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms by reaction with functional groups containing oxygen only in singly bound form
    • C07C45/71Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms by reaction with functional groups containing oxygen only in singly bound form being hydroxy groups
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C47/00Compounds having —CHO groups
    • C07C47/52Compounds having —CHO groups bound to carbon atoms of six—membered aromatic rings
    • C07C47/575Compounds having —CHO groups bound to carbon atoms of six—membered aromatic rings containing ether groups, groups, groups, or groups
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D233/00Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/04Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D233/28Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D233/30Oxygen or sulfur atoms
    • C07D233/32One oxygen atom

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
NLAANVRAGE7102324,A 1970-02-24 1971-02-22 Werkwijze voor de bereiding van cardiovasculair werkzame preparaten door een of meer 4-(3,4-dialkoxybenzyl)-2-imidazolidinonen in een voor therapeutische toediening geschikte vorm te brengen, alsmede werkwijze voor de bereiding van de betreffende verbindingen. NL171446C (nl)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US1376970A 1970-02-24 1970-02-24

Publications (3)

Publication Number Publication Date
NL7102324A true NL7102324A (en:Method) 1971-08-26
NL171446B NL171446B (nl) 1982-11-01
NL171446C NL171446C (nl) 1983-04-05

Family

ID=21761656

Family Applications (1)

Application Number Title Priority Date Filing Date
NLAANVRAGE7102324,A NL171446C (nl) 1970-02-24 1971-02-22 Werkwijze voor de bereiding van cardiovasculair werkzame preparaten door een of meer 4-(3,4-dialkoxybenzyl)-2-imidazolidinonen in een voor therapeutische toediening geschikte vorm te brengen, alsmede werkwijze voor de bereiding van de betreffende verbindingen.

Country Status (18)

Country Link
US (1) US3636039A (en:Method)
JP (1) JPS5421338B1 (en:Method)
BE (1) BE763298A (en:Method)
BR (1) BR7101125D0 (en:Method)
CA (1) CA967163A (en:Method)
CH (2) CH567483A5 (en:Method)
DE (1) DE2108438C2 (en:Method)
DK (2) DK134601B (en:Method)
FI (1) FI54919C (en:Method)
FR (1) FR2081537B1 (en:Method)
GB (1) GB1292768A (en:Method)
IE (1) IE35283B1 (en:Method)
IL (1) IL36237A (en:Method)
NL (1) NL171446C (en:Method)
NO (1) NO130680C (en:Method)
SE (1) SE369190B (en:Method)
YU (1) YU34407B (en:Method)
ZA (1) ZA711077B (en:Method)

Families Citing this family (32)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3932452A (en) * 1975-02-07 1976-01-13 Morton-Norwich Products, Inc. 1-Arylmethyl-2-imidazolidinones
US3966758A (en) * 1975-06-16 1976-06-29 Morton-Norwich Products, Inc. Anti-inflammatory 1-(substituted benzyl)-2-imidazolidinones
US4063022A (en) * 1976-11-22 1977-12-13 Morton-Norwich Products, Inc. Antisecretory 2-imidazolidinones
HU179019B (en) * 1978-11-01 1982-08-28 Gyogyszekutato Intezet Process for preparing 4-//3,4-dialkoxy-phenyl/-alkyl/- 2imidazolidinone derivatives
CA1188616A (en) * 1981-06-11 1985-06-11 Hoffmann-La Roche Limited Pharmaceutical preparations
HU215433B (hu) * 1986-04-29 2000-05-28 Pfizer Inc. Eljárás új 2-oxo-5-fenil-pirimidin-származékok előállítására
US5459145A (en) * 1988-01-19 1995-10-17 Pfizer Inc. Calcium independent camp phosphodiesterase inhibitor antidepressant
US5395935A (en) * 1992-05-08 1995-03-07 Pfizer Inc. Endo-bicyclo[2.2.1]heptan-2-ol and derived pharmaceutical agents
GB9312853D0 (en) * 1993-06-22 1993-08-04 Euro Celtique Sa Chemical compounds
US5591776A (en) * 1994-06-24 1997-01-07 Euro-Celtique, S.A. Pheynl or benzyl-substituted rolipram-based compounds for and method of inhibiting phosphodiesterase IV
US5922751A (en) 1994-06-24 1999-07-13 Euro-Celtique, S.A. Aryl pyrazole compound for inhibiting phosphodiesterase IV and methods of using same
US6066641A (en) * 1994-12-13 2000-05-23 Euro-Celtique S.A. Aryl thioxanthines
JP2001523213A (ja) * 1994-12-13 2001-11-20 ユーロ−セルティーク,エス.エイ. 三置換チオキサンチン類
US6025361A (en) * 1994-12-13 2000-02-15 Euro-Celtique, S.A. Trisubstituted thioxanthines
US6166041A (en) * 1995-10-11 2000-12-26 Euro-Celtique, S.A. 2-heteroaryl and 2-heterocyclic benzoxazoles as PDE IV inhibitors for the treatment of asthma
US6075016A (en) * 1996-04-10 2000-06-13 Euro-Celtique S.A. 6,5-fused aromatic ring systems having enhanced phosphodiesterase IV inhibitory activity
US5864037A (en) 1996-06-06 1999-01-26 Euro-Celtique, S.A. Methods for the synthesis of chemical compounds having PDE-IV inhibitory activity
US5744473A (en) * 1996-09-16 1998-04-28 Euro-Celtique, S.A. PDE IV inhibitors: "bis-compounds"
US6555572B2 (en) 2000-03-16 2003-04-29 Inflazyme Pharmaceuticals Ltd. Benzylated PDE4 inhibitors
US7772188B2 (en) 2003-01-28 2010-08-10 Ironwood Pharmaceuticals, Inc. Methods and compositions for the treatment of gastrointestinal disorders
AU2008261102B2 (en) 2007-06-04 2013-11-28 Bausch Health Ireland Limited Agonists of guanylate cyclase useful for the treatment of gastrointestinal disorders, inflammation, cancer and other disorders
US8034782B2 (en) 2008-07-16 2011-10-11 Synergy Pharmaceuticals, Inc. Agonists of guanylate cyclase useful for the treatment of gastrointestinal disorders, inflammation, cancer and other disorders
US8969514B2 (en) 2007-06-04 2015-03-03 Synergy Pharmaceuticals, Inc. Agonists of guanylate cyclase useful for the treatment of hypercholesterolemia, atherosclerosis, coronary heart disease, gallstone, obesity and other cardiovascular diseases
CA2930674A1 (en) 2008-06-04 2009-12-10 Synergy Pharmaceuticals Inc. Agonists of guanylate cyclase useful for the treatment of gastrointestinal disorders, inflammation, cancer and other disorders
US9616097B2 (en) 2010-09-15 2017-04-11 Synergy Pharmaceuticals, Inc. Formulations of guanylate cyclase C agonists and methods of use
EP2681236B1 (en) 2011-03-01 2018-01-03 Synergy Pharmaceuticals Inc. Process of preparing guanylate cyclase c agonists
JP6499591B2 (ja) 2013-02-25 2019-04-10 シナジー ファーマシューティカルズ インコーポレイテッド 結腸洗浄において用いるためのグアニル酸シクラーゼ受容体アゴニスト
EP2968439A2 (en) 2013-03-15 2016-01-20 Synergy Pharmaceuticals Inc. Compositions useful for the treatment of gastrointestinal disorders
AU2014235215A1 (en) 2013-03-15 2015-10-01 Synergy Pharmaceuticals Inc. Agonists of guanylate cyclase and their uses
CN113388007A (zh) 2013-06-05 2021-09-14 博士医疗爱尔兰有限公司 鸟苷酸环化酶c的超纯激动剂、制备和使用所述激动剂的方法
MX375926B (es) 2013-08-09 2025-03-07 Ardelyx Inc Compuestos y metodos para inhibir el transporte de fosfato.
EP3972599B1 (en) 2019-05-21 2025-10-22 Ardelyx, Inc. Combination for lowering serum phosphate in a patient

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH518285A (de) * 1968-05-01 1972-01-31 Hoffmann La Roche Verfahren zur Herstellung von neuen substituierten Benzylimidazolidinonen

Also Published As

Publication number Publication date
DK134601B (da) 1976-12-06
NL171446B (nl) 1982-11-01
IL36237A0 (en) 1971-04-28
DE2108438A1 (de) 1971-09-09
DK570075A (da) 1975-12-15
YU43971A (en) 1978-12-31
SE369190B (en:Method) 1974-08-12
CA967163A (en) 1975-05-06
ZA711077B (en) 1971-10-27
CH567482A5 (en:Method) 1975-10-15
NO130680B (en:Method) 1974-10-14
IL36237A (en) 1974-11-29
JPS5421338B1 (en:Method) 1979-07-30
IE35283B1 (en) 1976-01-07
CH567483A5 (en:Method) 1975-10-15
NO130680C (en:Method) 1975-01-22
NL171446C (nl) 1983-04-05
FI54919C (fi) 1979-04-10
DE2108438C2 (de) 1987-02-05
FI54919B (fi) 1978-12-29
FR2081537B1 (en:Method) 1974-08-23
US3636039A (en) 1972-01-18
BE763298A (fr) 1971-08-23
YU34407B (en) 1979-07-10
GB1292768A (en) 1972-10-11
DK134601C (en:Method) 1977-05-16
FR2081537A1 (en:Method) 1971-12-03
BR7101125D0 (pt) 1973-04-26
IE35283L (en) 1971-08-24

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Legal Events

Date Code Title Description
V1 Lapsed because of non-payment of the annual fee