NL6916151A - Antibacterial cephalosporin compsns - Google Patents
Antibacterial cephalosporin compsnsInfo
- Publication number
- NL6916151A NL6916151A NL6916151A NL6916151A NL6916151A NL 6916151 A NL6916151 A NL 6916151A NL 6916151 A NL6916151 A NL 6916151A NL 6916151 A NL6916151 A NL 6916151A NL 6916151 A NL6916151 A NL 6916151A
- Authority
- NL
- Netherlands
- Prior art keywords
- alpha
- compsns
- beta
- cephalosporin
- etoh
- Prior art date
Links
Landscapes
- Cephalosporin Compounds (AREA)
Abstract
Antibacterial cephalosporin compsns Compns. contg one or more of (a) 7-(1H-tetrazol-1-ylacetamido)-3-(5-methyl-1,3,4-thiadiazol-2-ylth- iomethyl)-3-cephem-4-carboxylic acid sodium salt (I) in alpha or beta form (b) 3,7-disubstd. cephalosporin derivs (II) described in NL 6805179 or their salts. (c) Esters of II are of value as antibacterials. I are obtained by appropriate alcohol treatment MeOH (>70%) or EtOH (>80%) converts alpha(5H2O) to beta(3/2 H2O) and MeOH (70%) or EtOH (80%) gives the opposite conversion. Further dessication gives the alpha and beta anhydrous forms which have increased stability.
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
NL6916151A NL173169C (en) | 1969-10-27 | 1969-10-27 | PROCESS FOR PREPARING A PHARMACEUTICAL PREPARATION WITH ANTIBACTERIAL ACTION AND PROCESS FOR PREPARING THE CEPHALOSPORINE DERIVATIVE REQUIRED FOR IT. |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
NL6916151A NL173169C (en) | 1969-10-27 | 1969-10-27 | PROCESS FOR PREPARING A PHARMACEUTICAL PREPARATION WITH ANTIBACTERIAL ACTION AND PROCESS FOR PREPARING THE CEPHALOSPORINE DERIVATIVE REQUIRED FOR IT. |
Publications (3)
Publication Number | Publication Date |
---|---|
NL6916151A true NL6916151A (en) | 1971-04-29 |
NL173169B NL173169B (en) | 1983-07-18 |
NL173169C NL173169C (en) | 1983-12-16 |
Family
ID=19808227
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
NL6916151A NL173169C (en) | 1969-10-27 | 1969-10-27 | PROCESS FOR PREPARING A PHARMACEUTICAL PREPARATION WITH ANTIBACTERIAL ACTION AND PROCESS FOR PREPARING THE CEPHALOSPORINE DERIVATIVE REQUIRED FOR IT. |
Country Status (1)
Country | Link |
---|---|
NL (1) | NL173169C (en) |
Cited By (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3892737A (en) * | 1971-08-20 | 1975-07-01 | Takeda Chemical Industries Ltd | Cephalosporins |
US3989694A (en) | 1974-12-27 | 1976-11-02 | Smithkline Corporation | 7-Acyl-3-(substituted triazolyl thiomethyl)cephalosporins |
US4060610A (en) | 1974-12-27 | 1977-11-29 | Smithkline Corporation | Pharmaceutical compositions comprising 7-acyl-3-(substituted triazolyl thiomethyl)-cephalosporins and methods of treating bacterial infections |
US4066762A (en) * | 1976-07-12 | 1978-01-03 | Smithkline Corporation | Derivatives of 7-(2-substituted-2-hydroxyiminoacetamido)-3-(1-substituted tetrazol-5-ylthiomethyl-3-cephem-4-carboxylic acid |
US4278670A (en) * | 1976-07-12 | 1981-07-14 | Smithkline Corporation | 7-Alpha-oxyiminoacylcephalosporins |
US4286089A (en) | 1974-12-27 | 1981-08-25 | Smithkline Corporation | 7-Acyl-3-(substituted tetrazolyl thiomethyl)cephalosporins |
US4576937A (en) * | 1984-02-29 | 1986-03-18 | Smithkline Beckman Corporation | 7-D-Mandelamido-3(1-sulfomethyltetrazol-5-yl)thiomethyl-3-cephem-4-carboxylic acid monosodium salt |
-
1969
- 1969-10-27 NL NL6916151A patent/NL173169C/en active
Cited By (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3892737A (en) * | 1971-08-20 | 1975-07-01 | Takeda Chemical Industries Ltd | Cephalosporins |
US3989694A (en) | 1974-12-27 | 1976-11-02 | Smithkline Corporation | 7-Acyl-3-(substituted triazolyl thiomethyl)cephalosporins |
US4060610A (en) | 1974-12-27 | 1977-11-29 | Smithkline Corporation | Pharmaceutical compositions comprising 7-acyl-3-(substituted triazolyl thiomethyl)-cephalosporins and methods of treating bacterial infections |
US4286089A (en) | 1974-12-27 | 1981-08-25 | Smithkline Corporation | 7-Acyl-3-(substituted tetrazolyl thiomethyl)cephalosporins |
US4066762A (en) * | 1976-07-12 | 1978-01-03 | Smithkline Corporation | Derivatives of 7-(2-substituted-2-hydroxyiminoacetamido)-3-(1-substituted tetrazol-5-ylthiomethyl-3-cephem-4-carboxylic acid |
US4278670A (en) * | 1976-07-12 | 1981-07-14 | Smithkline Corporation | 7-Alpha-oxyiminoacylcephalosporins |
US4576937A (en) * | 1984-02-29 | 1986-03-18 | Smithkline Beckman Corporation | 7-D-Mandelamido-3(1-sulfomethyltetrazol-5-yl)thiomethyl-3-cephem-4-carboxylic acid monosodium salt |
Also Published As
Publication number | Publication date |
---|---|
NL173169B (en) | 1983-07-18 |
NL173169C (en) | 1983-12-16 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
V3 | Additional patents lapsed at the same time as the main patent |