NL6916151A - Antibacterial cephalosporin compsns - Google Patents

Antibacterial cephalosporin compsns

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Publication number
NL6916151A
NL6916151A NL6916151A NL6916151A NL6916151A NL 6916151 A NL6916151 A NL 6916151A NL 6916151 A NL6916151 A NL 6916151A NL 6916151 A NL6916151 A NL 6916151A NL 6916151 A NL6916151 A NL 6916151A
Authority
NL
Netherlands
Prior art keywords
alpha
compsns
beta
cephalosporin
etoh
Prior art date
Application number
NL6916151A
Other versions
NL173169B (en
NL173169C (en
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed filed Critical
Priority to NL6916151A priority Critical patent/NL173169C/en
Publication of NL6916151A publication Critical patent/NL6916151A/en
Publication of NL173169B publication Critical patent/NL173169B/en
Application granted granted Critical
Publication of NL173169C publication Critical patent/NL173169C/en

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  • Cephalosporin Compounds (AREA)

Abstract

Antibacterial cephalosporin compsns Compns. contg one or more of (a) 7-(1H-tetrazol-1-ylacetamido)-3-(5-methyl-1,3,4-thiadiazol-2-ylth- iomethyl)-3-cephem-4-carboxylic acid sodium salt (I) in alpha or beta form (b) 3,7-disubstd. cephalosporin derivs (II) described in NL 6805179 or their salts. (c) Esters of II are of value as antibacterials. I are obtained by appropriate alcohol treatment MeOH (>70%) or EtOH (>80%) converts alpha(5H2O) to beta(3/2 H2O) and MeOH (70%) or EtOH (80%) gives the opposite conversion. Further dessication gives the alpha and beta anhydrous forms which have increased stability.
NL6916151A 1969-10-27 1969-10-27 PROCESS FOR PREPARING A PHARMACEUTICAL PREPARATION WITH ANTIBACTERIAL ACTION AND PROCESS FOR PREPARING THE CEPHALOSPORINE DERIVATIVE REQUIRED FOR IT. NL173169C (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
NL6916151A NL173169C (en) 1969-10-27 1969-10-27 PROCESS FOR PREPARING A PHARMACEUTICAL PREPARATION WITH ANTIBACTERIAL ACTION AND PROCESS FOR PREPARING THE CEPHALOSPORINE DERIVATIVE REQUIRED FOR IT.

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
NL6916151A NL173169C (en) 1969-10-27 1969-10-27 PROCESS FOR PREPARING A PHARMACEUTICAL PREPARATION WITH ANTIBACTERIAL ACTION AND PROCESS FOR PREPARING THE CEPHALOSPORINE DERIVATIVE REQUIRED FOR IT.

Publications (3)

Publication Number Publication Date
NL6916151A true NL6916151A (en) 1971-04-29
NL173169B NL173169B (en) 1983-07-18
NL173169C NL173169C (en) 1983-12-16

Family

ID=19808227

Family Applications (1)

Application Number Title Priority Date Filing Date
NL6916151A NL173169C (en) 1969-10-27 1969-10-27 PROCESS FOR PREPARING A PHARMACEUTICAL PREPARATION WITH ANTIBACTERIAL ACTION AND PROCESS FOR PREPARING THE CEPHALOSPORINE DERIVATIVE REQUIRED FOR IT.

Country Status (1)

Country Link
NL (1) NL173169C (en)

Cited By (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3892737A (en) * 1971-08-20 1975-07-01 Takeda Chemical Industries Ltd Cephalosporins
US3989694A (en) 1974-12-27 1976-11-02 Smithkline Corporation 7-Acyl-3-(substituted triazolyl thiomethyl)cephalosporins
US4060610A (en) 1974-12-27 1977-11-29 Smithkline Corporation Pharmaceutical compositions comprising 7-acyl-3-(substituted triazolyl thiomethyl)-cephalosporins and methods of treating bacterial infections
US4066762A (en) * 1976-07-12 1978-01-03 Smithkline Corporation Derivatives of 7-(2-substituted-2-hydroxyiminoacetamido)-3-(1-substituted tetrazol-5-ylthiomethyl-3-cephem-4-carboxylic acid
US4278670A (en) * 1976-07-12 1981-07-14 Smithkline Corporation 7-Alpha-oxyiminoacylcephalosporins
US4286089A (en) 1974-12-27 1981-08-25 Smithkline Corporation 7-Acyl-3-(substituted tetrazolyl thiomethyl)cephalosporins
US4576937A (en) * 1984-02-29 1986-03-18 Smithkline Beckman Corporation 7-D-Mandelamido-3(1-sulfomethyltetrazol-5-yl)thiomethyl-3-cephem-4-carboxylic acid monosodium salt

Cited By (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3892737A (en) * 1971-08-20 1975-07-01 Takeda Chemical Industries Ltd Cephalosporins
US3989694A (en) 1974-12-27 1976-11-02 Smithkline Corporation 7-Acyl-3-(substituted triazolyl thiomethyl)cephalosporins
US4060610A (en) 1974-12-27 1977-11-29 Smithkline Corporation Pharmaceutical compositions comprising 7-acyl-3-(substituted triazolyl thiomethyl)-cephalosporins and methods of treating bacterial infections
US4286089A (en) 1974-12-27 1981-08-25 Smithkline Corporation 7-Acyl-3-(substituted tetrazolyl thiomethyl)cephalosporins
US4066762A (en) * 1976-07-12 1978-01-03 Smithkline Corporation Derivatives of 7-(2-substituted-2-hydroxyiminoacetamido)-3-(1-substituted tetrazol-5-ylthiomethyl-3-cephem-4-carboxylic acid
US4278670A (en) * 1976-07-12 1981-07-14 Smithkline Corporation 7-Alpha-oxyiminoacylcephalosporins
US4576937A (en) * 1984-02-29 1986-03-18 Smithkline Beckman Corporation 7-D-Mandelamido-3(1-sulfomethyltetrazol-5-yl)thiomethyl-3-cephem-4-carboxylic acid monosodium salt

Also Published As

Publication number Publication date
NL173169B (en) 1983-07-18
NL173169C (en) 1983-12-16

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Legal Events

Date Code Title Description
V3 Additional patents lapsed at the same time as the main patent