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Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur
(AREA)
Abstract
Preparing 17beta-spiro-1',2'-oxiranes of the oestrane series by reaction of 17-keto-oestranes with excess of diMe-sulphuronium-methylide in a solvent, e.g. diMe-sulphoxide or THF at -10 to +20 deg., pref. at 0 deg. 3-Methoxy-oestra-1,3,5(10)-trien-17beta-spiro-1',2'-oxirane (I) (specifically claimed).
NL6901216A1969-01-241969-01-2417beta-spiro-oxiranes of the oestrane series
NL6901216A
(en)