FR2074633A1 - Prepn of 9 alpha - 11 beta dichloro - steroids - Google Patents

Prepn of 9 alpha - 11 beta dichloro - steroids

Info

Publication number
FR2074633A1
FR2074633A1 FR7001104A FR7001104A FR2074633A1 FR 2074633 A1 FR2074633 A1 FR 2074633A1 FR 7001104 A FR7001104 A FR 7001104A FR 7001104 A FR7001104 A FR 7001104A FR 2074633 A1 FR2074633 A1 FR 2074633A1
Authority
FR
France
Prior art keywords
alpha
prepn
steroids
dichloro
beta
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
FR7001104A
Other languages
French (fr)
Other versions
FR2074633B1 (en
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Roche Palo Alto LLC
Original Assignee
Roche Palo Alto LLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Roche Palo Alto LLC filed Critical Roche Palo Alto LLC
Priority to FR7001104A priority Critical patent/FR2074633A1/en
Publication of FR2074633A1 publication Critical patent/FR2074633A1/en
Application granted granted Critical
Publication of FR2074633B1 publication Critical patent/FR2074633B1/fr
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J5/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J75/00—Processes for the preparation of steroids in general

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Steroid Compounds (AREA)

Abstract

9 alpha-11B-dichlorosteroids are prepd. by reacting a 9 alpha-unsubstd. 11B-hydroxysteroid with SOCl2 and Cl2, pref. in an inert solvent in the presence of tertiary amine at -10 degrees to +30 degrees C.
FR7001104A 1970-01-13 1970-01-13 Prepn of 9 alpha - 11 beta dichloro - steroids Granted FR2074633A1 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
FR7001104A FR2074633A1 (en) 1970-01-13 1970-01-13 Prepn of 9 alpha - 11 beta dichloro - steroids

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR7001104A FR2074633A1 (en) 1970-01-13 1970-01-13 Prepn of 9 alpha - 11 beta dichloro - steroids

Publications (2)

Publication Number Publication Date
FR2074633A1 true FR2074633A1 (en) 1971-10-08
FR2074633B1 FR2074633B1 (en) 1973-01-12

Family

ID=9048953

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7001104A Granted FR2074633A1 (en) 1970-01-13 1970-01-13 Prepn of 9 alpha - 11 beta dichloro - steroids

Country Status (1)

Country Link
FR (1) FR2074633A1 (en)

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2894963A (en) * 1958-06-20 1959-07-14 Scherico Ltd 9,11-dihalogeno-4-pregnenes and 1,4-pregnadienes
US3201391A (en) * 1959-02-18 1965-08-17 Syntex Corp 6alpha, 9alpha, 11beta-trichloro and 6alpha-fluoro-9alpha, 11beta-dichloro pregnenes

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2894963A (en) * 1958-06-20 1959-07-14 Scherico Ltd 9,11-dihalogeno-4-pregnenes and 1,4-pregnadienes
US3201391A (en) * 1959-02-18 1965-08-17 Syntex Corp 6alpha, 9alpha, 11beta-trichloro and 6alpha-fluoro-9alpha, 11beta-dichloro pregnenes

Also Published As

Publication number Publication date
FR2074633B1 (en) 1973-01-12

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