NL2031214B1 - Nasal spray device and method of spraying a liquid formulation - Google Patents

Nasal spray device and method of spraying a liquid formulation Download PDF

Info

Publication number
NL2031214B1
NL2031214B1 NL2031214A NL2031214A NL2031214B1 NL 2031214 B1 NL2031214 B1 NL 2031214B1 NL 2031214 A NL2031214 A NL 2031214A NL 2031214 A NL2031214 A NL 2031214A NL 2031214 B1 NL2031214 B1 NL 2031214B1
Authority
NL
Netherlands
Prior art keywords
liquid formulation
nasal
spray
micropores
spray device
Prior art date
Application number
NL2031214A
Other languages
English (en)
Dutch (nl)
Inventor
Johannes Maria Van Rijn Cornelis
Martinus Verhoeven Franciscus
Original Assignee
Medspray B V
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Medspray B V filed Critical Medspray B V
Priority to NL2031214A priority Critical patent/NL2031214B1/en
Priority to JP2024553323A priority patent/JP2025509265A/ja
Priority to CN202380037986.7A priority patent/CN119136870A/zh
Priority to PCT/IB2023/052265 priority patent/WO2023170629A1/en
Priority to US18/845,046 priority patent/US20250177668A1/en
Priority to EP23712355.9A priority patent/EP4489826A1/en
Application granted granted Critical
Publication of NL2031214B1 publication Critical patent/NL2031214B1/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M11/00Sprayers or atomisers specially adapted for therapeutic purposes
    • A61M11/001Particle size control
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00Inhalators
    • A61M15/08Inhaling devices inserted into the nose
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/007Pulmonary tract; Aromatherapy
    • A61K9/0073Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
    • A61K9/0078Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy for inhalation via a nebulizer such as a jet nebulizer, ultrasonic nebulizer, e.g. in the form of aqueous drug solutions or dispersions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M11/00Sprayers or atomisers specially adapted for therapeutic purposes
    • A61M11/006Sprayers or atomisers specially adapted for therapeutic purposes operated by applying mechanical pressure to the liquid to be sprayed or atomised
    • A61M11/007Syringe-type or piston-type sprayers or atomisers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00Inhalators
    • A61M15/009Inhalators using medicine packages with incorporated spraying means, e.g. aerosol cans
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B05SPRAYING OR ATOMISING IN GENERAL; APPLYING FLUENT MATERIALS TO SURFACES, IN GENERAL
    • B05BSPRAYING APPARATUS; ATOMISING APPARATUS; NOZZLES
    • B05B11/00Single-unit hand-held apparatus in which flow of contents is produced by the muscular force of the operator at the moment of use
    • B05B11/01Single-unit hand-held apparatus in which flow of contents is produced by the muscular force of the operator at the moment of use characterised by the means producing the flow
    • B05B11/02Membranes or pistons acting on the contents inside the container, e.g. follower pistons
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2202/00Special media to be introduced, removed or treated
    • A61M2202/04Liquids
    • A61M2202/0468Liquids non-physiological
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00General characteristics of the apparatus
    • A61M2205/02General characteristics of the apparatus characterised by a particular materials
    • A61M2205/0211Ceramics

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Anesthesiology (AREA)
  • Hematology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pulmonology (AREA)
  • Otolaryngology (AREA)
  • Chemical & Material Sciences (AREA)
  • Mechanical Engineering (AREA)
  • Dispersion Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Medicinal Chemistry (AREA)
  • Medicinal Preparation (AREA)
NL2031214A 2022-03-09 2022-03-09 Nasal spray device and method of spraying a liquid formulation NL2031214B1 (en)

Priority Applications (6)

Application Number Priority Date Filing Date Title
NL2031214A NL2031214B1 (en) 2022-03-09 2022-03-09 Nasal spray device and method of spraying a liquid formulation
JP2024553323A JP2025509265A (ja) 2022-03-09 2023-03-09 鼻腔用スプレー装置および液体製剤を噴霧する方法
CN202380037986.7A CN119136870A (zh) 2022-03-09 2023-03-09 鼻喷雾装置和雾化液体制剂的方法
PCT/IB2023/052265 WO2023170629A1 (en) 2022-03-09 2023-03-09 Nasal spray device and method of nebulizing a liquid formulation
US18/845,046 US20250177668A1 (en) 2022-03-09 2023-03-09 Nasal Spray Device and Method of Nebulizing a Liquid Formulation
EP23712355.9A EP4489826A1 (en) 2022-03-09 2023-03-09 Nasal spray device and method of nebulizing a liquid formulation

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
NL2031214A NL2031214B1 (en) 2022-03-09 2022-03-09 Nasal spray device and method of spraying a liquid formulation

Publications (1)

Publication Number Publication Date
NL2031214B1 true NL2031214B1 (en) 2023-09-19

Family

ID=82196761

Family Applications (1)

Application Number Title Priority Date Filing Date
NL2031214A NL2031214B1 (en) 2022-03-09 2022-03-09 Nasal spray device and method of spraying a liquid formulation

Country Status (6)

Country Link
US (1) US20250177668A1 (enExample)
EP (1) EP4489826A1 (enExample)
JP (1) JP2025509265A (enExample)
CN (1) CN119136870A (enExample)
NL (1) NL2031214B1 (enExample)
WO (1) WO2023170629A1 (enExample)

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US12298316B2 (en) 2014-02-18 2025-05-13 Cyrano Therapeutics, Inc. Methods and compositions for diagnosing and treating loss and/or distortion of taste or smell
US12329753B2 (en) 2008-07-23 2025-06-17 Cyrano Therapeutics, Inc. Phosphodiesterase inhibitor treatment
US12569493B2 (en) 2020-03-24 2026-03-10 Cyrano Therapeutics Inc. Treatment of chemosensory dysfunction from a coronavirus infection

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN117482337A (zh) * 2023-11-24 2024-02-02 北京宝诺康医药科技有限公司 一种可将药液输送至窦口鼻道复合体的网式雾化器
US20250205437A1 (en) * 2023-12-22 2025-06-26 Rare Air Health, Inc. Microfluidic platform for shear-less aerosolization of lipid nanoparticles for messenger rna inhalation

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2019190316A1 (en) * 2018-03-26 2019-10-03 Medspray B.V. Spray device, spray unit and spray cartridge

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU9089591A (en) * 1990-12-17 1992-07-22 Minnesota Mining And Manufacturing Company Inhaler
CA2561845C (en) * 2004-04-02 2014-03-25 The Government Of The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services, Centers For Disease Control And Prevention Aerosol delivery systems and methods
US7958887B2 (en) * 2006-03-10 2011-06-14 Aradigm Corporation Nozzle pore configuration for intrapulmonary delivery of aerosolized formulations
ES2628077T3 (es) * 2009-02-27 2017-08-01 Pari GmbH Spezialisten für effektive Inhalation Dispositivo de inhalación de aerosol
NL2002787C2 (en) * 2009-04-23 2010-10-26 Medspray Xmems Bv Atomising body, atomising device, inhaler, manufacturing method of manufacturing an atomising body and assembly method for assembling an atomising device.
EP3563894B1 (en) * 2018-05-04 2021-12-22 Boehringer Ingelheim International GmbH Nebulizer and container

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2019190316A1 (en) * 2018-03-26 2019-10-03 Medspray B.V. Spray device, spray unit and spray cartridge

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
PER G DJUPESLAND ET AL: "The nasal approach to delivering treatment for brain diseases: an anatomic, physiologic, and delivery technology overview", THERAPEUTIC DELIVERY, vol. 5, no. 6, 1 June 2014 (2014-06-01), GB, pages 709 - 733, XP055605330, ISSN: 2041-5990, DOI: 10.4155/tde.14.41 *
THIAGO C. CARVALHO ET AL: "The function and performance of aqueous aerosol devices for inhalation therapy", JOURNAL OF PHARMACY AND PHARMACOLOGY : JPP, vol. 68, no. 5, 8 April 2016 (2016-04-08), GB, pages 556 - 578, XP055730729, ISSN: 0022-3573, DOI: 10.1111/jphp.12541 *

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US12329753B2 (en) 2008-07-23 2025-06-17 Cyrano Therapeutics, Inc. Phosphodiesterase inhibitor treatment
US12298316B2 (en) 2014-02-18 2025-05-13 Cyrano Therapeutics, Inc. Methods and compositions for diagnosing and treating loss and/or distortion of taste or smell
US12569493B2 (en) 2020-03-24 2026-03-10 Cyrano Therapeutics Inc. Treatment of chemosensory dysfunction from a coronavirus infection

Also Published As

Publication number Publication date
WO2023170629A1 (en) 2023-09-14
CN119136870A (zh) 2024-12-13
JP2025509265A (ja) 2025-04-11
US20250177668A1 (en) 2025-06-05
EP4489826A1 (en) 2025-01-15

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