NL191150C - N-(L-leucyl) doxorubicine en zuur-additiezouten daarvan, werkwijze ter bereiding en farmaceutische preparaat. - Google Patents

N-(L-leucyl) doxorubicine en zuur-additiezouten daarvan, werkwijze ter bereiding en farmaceutische preparaat.

Info

Publication number
NL191150C
NL191150C NL7905953A NL7905953A NL191150C NL 191150 C NL191150 C NL 191150C NL 7905953 A NL7905953 A NL 7905953A NL 7905953 A NL7905953 A NL 7905953A NL 191150 C NL191150 C NL 191150C
Authority
NL
Netherlands
Prior art keywords
preparation
leucyl
doxorubicin
acid addition
addition salts
Prior art date
Application number
NL7905953A
Other languages
English (en)
Dutch (nl)
Other versions
NL7905953A (nl
NL191150B (nl
Original Assignee
Ass A But Scienti Internationa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ass A But Scienti Internationa filed Critical Ass A But Scienti Internationa
Publication of NL7905953A publication Critical patent/NL7905953A/nl
Publication of NL191150B publication Critical patent/NL191150B/xx
Application granted granted Critical
Publication of NL191150C publication Critical patent/NL191150C/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/20—Carbocyclic rings
    • C07H15/24—Condensed ring systems having three or more rings
    • C07H15/252—Naphthacene radicals, e.g. daunomycins, adriamycins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biotechnology (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
NL7905953A 1978-08-03 1979-08-02 N-(L-leucyl) doxorubicine en zuur-additiezouten daarvan, werkwijze ter bereiding en farmaceutische preparaat. NL191150C (nl)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
BE869485 1978-08-03
BE869485 1978-08-03

Publications (3)

Publication Number Publication Date
NL7905953A NL7905953A (nl) 1980-02-05
NL191150B NL191150B (nl) 1994-09-16
NL191150C true NL191150C (nl) 1995-02-16

Family

ID=3861689

Family Applications (1)

Application Number Title Priority Date Filing Date
NL7905953A NL191150C (nl) 1978-08-03 1979-08-02 N-(L-leucyl) doxorubicine en zuur-additiezouten daarvan, werkwijze ter bereiding en farmaceutische preparaat.

Country Status (6)

Country Link
US (1) US4296105A (cs)
JP (1) JPS5522697A (cs)
CA (1) CA1115694A (cs)
FR (1) FR2432525A1 (cs)
GB (1) GB2027024B (cs)
NL (1) NL191150C (cs)

Families Citing this family (36)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5124318A (en) * 1985-08-02 1992-06-23 Farmitalia Carlo Erba S.R.L. Injectable ready-to-use solutions containing an antitumor anthracycline glycoside
US5977082A (en) 1985-08-02 1999-11-02 Pharmacia & Upjohn Company Injectable ready-to-use solutions containing an antitumor anthracycline glycoside
US5124317A (en) 1985-08-02 1992-06-23 Farmitalia Carlo Erba S.P.A. Injectable ready-to-use solutions containing an antitumor anthracycline glycoside
US5866679A (en) * 1994-06-28 1999-02-02 Merck & Co., Inc. Peptides
US6143864A (en) * 1994-06-28 2000-11-07 Merck & Co., Inc. Peptides
US5599686A (en) * 1994-06-28 1997-02-04 Merck & Co., Inc. Peptides
ATE380559T1 (de) * 1994-08-19 2007-12-15 Wallone Region Konjugate enthaltend ein antitumorales mittel und deren verwendung
BE1008581A3 (fr) * 1994-08-19 1996-06-04 Wallone Region Prodrogues, composition pharmaceutique les comprenant et leur utilisation.
JP2543434Y2 (ja) * 1996-04-15 1997-08-06 マツダ株式会社 エンジンの排気管構造
US5998362A (en) * 1996-09-12 1999-12-07 Merck & Co., Inc. Conjugates useful in the treatment of prostate cancer
US5948750A (en) * 1996-10-30 1999-09-07 Merck & Co., Inc. Conjugates useful in the treatment of prostate cancer
US6391305B1 (en) 1997-09-10 2002-05-21 Merck & Co., Inc. Conjugates useful in the treatment of prostate cancer
US20040081659A1 (en) * 1997-12-02 2004-04-29 Merck & Co., Inc. Conjugates useful in the treatment of prostate cancer
ZA9810974B (en) * 1997-12-02 1999-06-03 Merck & Co Inc Conjugates useful in the treatment of prostate cancer
BR9815116A (pt) * 1997-12-02 2000-10-10 Merck & Co Inc Conjugado, composição farmacêutica, e, processo para tratar câncer de próstata, e para tratar hiperplasia prostática benigna
US6174858B1 (en) 1998-11-17 2001-01-16 Merck & Co., Inc. Conjugates useful in the treatment of prostate cancer
US7425541B2 (en) * 1998-12-11 2008-09-16 Medarex, Inc. Enzyme-cleavable prodrug compounds
EP1225918A2 (en) 1999-10-19 2002-07-31 Merck & Co., Inc. Conjugates useful in the treatment of prostate cancer
JP2003512475A (ja) 1999-10-27 2003-04-02 メルク エンド カムパニー インコーポレーテッド 前立腺癌の治療に有用な複合体の塩形態
AU1374601A (en) * 1999-11-12 2001-05-30 Angiotech International Ag Compositions and methods for treating disease utilizing a combination of radioactive therapy and cell-cycle inhibitors
AU6685301A (en) 2000-06-14 2001-12-24 Corixa Corp Prodrug compounds with isoleucine
US7402556B2 (en) * 2000-08-24 2008-07-22 Medarex, Inc. Prodrugs activated by plasmin and their use in cancer chemotherapy
US20030232760A1 (en) * 2001-09-21 2003-12-18 Merck & Co., Inc. Conjugates useful in the treatment of prostate cancer
US20030216758A1 (en) * 2001-12-28 2003-11-20 Angiotech Pharmaceuticals, Inc. Coated surgical patches
NZ536308A (en) 2002-05-24 2009-01-31 Angiotech Int Ag Compositions and methods for coating medical implants
US8313760B2 (en) 2002-05-24 2012-11-20 Angiotech International Ag Compositions and methods for coating medical implants
CA2497349C (en) 2002-09-26 2008-07-08 Angiotech International Ag Perivascular wraps
JP2006516548A (ja) 2002-12-30 2006-07-06 アンジオテック インターナショナル アクツィエン ゲゼルシャフト 迅速ゲル化ポリマー組成物からの薬物送達法
JP2007514472A (ja) * 2003-11-20 2007-06-07 アンジオテック インターナショナル アーゲー 軟組織移植片および瘢痕化抑制剤
EP3075247B1 (en) 2004-02-02 2022-10-12 BioSight Ltd. Conjugates for cancer therapy and diagnosis
AU2005100176A4 (en) * 2005-03-01 2005-04-07 Gym Tv Pty Ltd Garbage bin clip
US9789209B2 (en) 2013-03-14 2017-10-17 The Regents Of The University Of California, Berke Activatable membrane-interacting peptides and methods of use
US12064445B2 (en) 2015-12-03 2024-08-20 Biosight Ltd. Cytarabine conjugates for cancer therapy
US11104698B2 (en) 2015-12-03 2021-08-31 Biosight Ltd. Salts of conjugates for cancer therapy
WO2017093993A1 (en) 2015-12-03 2017-06-08 Biosight Ltd. Cytarabine conjugates for cancer therapy
US12071450B2 (en) 2015-12-03 2024-08-27 Biosight Ltd. Salts of conjugates for cancer therapy

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR1578734A (cs) * 1967-11-28 1969-08-22
FR7164M (cs) * 1968-02-22 1969-08-04
FI51808C (fi) * 1968-07-15 1977-04-12 Rhone Poulenc Sa Menetelmä uusien kasvainten naftaseenijohdannaisten valmistamiseksi.
GB1500421A (en) * 1975-01-22 1978-02-08 Farmaceutici Italia Optically active anthracyclinones
US4012448A (en) * 1976-01-15 1977-03-15 Stanford Research Institute Synthesis of adriamycin and 7,9-epiadriamycin
FR2430425A1 (fr) * 1978-07-07 1980-02-01 Rhone Poulenc Ind Nouveaux derives de la daunorubicine, leur preparation et les compositions pharmaceutiques qui les contiennent

Also Published As

Publication number Publication date
GB2027024B (en) 1983-04-27
US4296105A (en) 1981-10-20
FR2432525B1 (cs) 1983-12-02
NL7905953A (nl) 1980-02-05
JPS6259715B2 (cs) 1987-12-12
GB2027024A (en) 1980-02-13
JPS5522697A (en) 1980-02-18
CA1115694A (en) 1982-01-05
FR2432525A1 (fr) 1980-02-29
NL191150B (nl) 1994-09-16

Similar Documents

Publication Publication Date Title
NL191150C (nl) N-(L-leucyl) doxorubicine en zuur-additiezouten daarvan, werkwijze ter bereiding en farmaceutische preparaat.
BE847742A (fr) Nouvelles imidazolidines, procede de preparation et compositions pharmaceutiques
FI792009A7 (fi) 3-aminopropoksiaryylijohdannaisia, niiden valmistus ja niitä sisältävät farmaseuttiset koostumukset.
IT1194900B (it) N-(fenossialchile)immidazoli,relative composizioni farmaceutiche e procedimento per la loro fabbricazione
NL7610199A (nl) Werkwijze om naftochinoncarbonzuuresterderivaten te bereiden en om pesticidepreparaten te bereiden, welke deze bevatten.
FI791656A7 (fi) Vatsahapon eritystä vastustavia tiadiatsolijohdannaisia, niiden valmistusmenetelmiä ja niitä sisältävifarmaseuttisia valmisteita.
FI802918A7 (fi) Aminohappojohdannaisia ja menetelmä niiden valmistamiseksi.
FI813862A7 (fi) Uusia 8-aryylialkyyli-3- fenyyli-3- nortropanoleja, niiden happoadditiosuoloja, näitä sisältäviä lääkeainelääkeaineita ja menetelmiä niiden valmistamiseksi.
ATE921T1 (de) Saeureadditionssalze von 2-beta, 16-beta-bis-piperidino-an drostan-16-beta-monoquaternaeren ammoniumderivaten und diese enthaltende pharmazeutische zusammensetzungen.
IT7926362A0 (it) Composto 2-metil-diidropiridinico, procedimenti per la sua preparazione e composizione farmaceutica che lo comprende.
FI801168A7 (fi) Penem-3- karboksyylihapon johdannaiset, niiden valmistus ja käyttö.
NL190662B (nl) Alfa-halogeenmethyl-alfa-aminozuurderivaten en farmaceutisch preparaat dat dit bevat.
DE2961804D1 (en) N-(3-benzoylpropyl)-spiro-(dihydrobenzofuranpiperidines and -pyrrolidines), derivatives thereof, methods for their preparation and their use for medicines
NL188645C (nl) 1-azaxanthon-3-carbonzuurverbindingen en farmaceutische preparaten die deze verbindingen bevatten.
NL7901241A (nl) Nieuwe gesubstitueerde 2-fenylimino-imidazolidinen, de zuuradditiezouten daarvan, farmaceutische preparaten die deze bevatten, alsmede werkwijze voor de bereiding daarvan.
FI854178A7 (fi) 1,2,4-triatsolo-karbamaatti ja sen happoadditiosuolat, näiden valmistusmenetelmät ja lääkeaineet.
NL174345B (nl) Zuur alkalicitraat, werkwijze ter bereiding daarvan en therapeutisch preparaat.
NL7900264A (nl) 4-pyridon-3-carbonzuurderivaten alsmede de bereiding ervan.
FI803202A7 (fi) Fosfonohydroksietikkahappo, sen valmistusmenetelmä sekä käyttö lääkeaineena.
NL7903769A (nl) Di-o-n-alkylglycerolderivaten en farmaceutische preparaten daarvan.
NL187397C (nl) Farmaceutische preparaten, 20,21-dinoreburnamenineverbindingen daarvoor en werkwijze voor hun bereiding.
FI791424A7 (fi) Substituoidut 8-hydroksi-1-fenyyli-2,3,4,5-tetrahydro-1H-3- bentsatsepiinit, menetelmä niiden valmistamiseksi jniitä sisältävät farmaseuttiset seokset.
BE865816A (fr) Derives d'acide benzoique, leur procede de preparation et leur application therapeutique.
FI803908A7 (fi) Uusia pyrrolobentsotriatsepiineja, niiden valmistus ja niitä sisältävät farmaseuttiset koostumukset.
FI793848A7 (fi) Bensoksadiatsoleja ja bensotiadiatsoleja, niiden valmistus ja farmaseuttisia yhdisteitä, jotka sisältävät näitä

Legal Events

Date Code Title Description
A85 Still pending on 85-01-01
BA A request for search or an international-type search has been filed
BB A search report has been drawn up
BC A request for examination has been filed
V1 Lapsed because of non-payment of the annual fee

Effective date: 19960301