NL185211B - PROCESS FOR PREPARING THE METHYL ESTER OF ALFA-L-ASPARTYL-L-PHENYLALANINE. - Google Patents

PROCESS FOR PREPARING THE METHYL ESTER OF ALFA-L-ASPARTYL-L-PHENYLALANINE.

Info

Publication number
NL185211B
NL185211B NLAANVRAGE7714351,A NL7714351A NL185211B NL 185211 B NL185211 B NL 185211B NL 7714351 A NL7714351 A NL 7714351A NL 185211 B NL185211 B NL 185211B
Authority
NL
Netherlands
Prior art keywords
aspartyl
alfa
phenylalanine
preparing
methyl ester
Prior art date
Application number
NLAANVRAGE7714351,A
Other languages
Dutch (nl)
Other versions
NL185211C (en
NL7714351A (en
Original Assignee
Monsanto Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Monsanto Co filed Critical Monsanto Co
Publication of NL7714351A publication Critical patent/NL7714351A/en
Publication of NL185211B publication Critical patent/NL185211B/en
Application granted granted Critical
Publication of NL185211C publication Critical patent/NL185211C/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06—Dipeptides
    • C07K5/06104—Dipeptides with the first amino acid being acidic
    • C07K5/06113—Asp- or Asn-amino acid
    • C07K5/06121—Asp- or Asn-amino acid the second amino acid being aromatic or cycloaliphatic
    • C07K5/0613—Aspartame

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Peptides Or Proteins (AREA)
  • Seasonings (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
NLAANVRAGE7714351,A 1976-12-27 1977-12-23 PROCESS FOR PREPARING THE METHYL ESTER OF ALFA-L-ASPARTYL-L-PHENYLALANINE. NL185211C (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US75429776A 1976-12-27 1976-12-27

Publications (3)

Publication Number Publication Date
NL7714351A NL7714351A (en) 1978-06-29
NL185211B true NL185211B (en) 1989-09-18
NL185211C NL185211C (en) 1990-02-16

Family

ID=25034194

Family Applications (1)

Application Number Title Priority Date Filing Date
NLAANVRAGE7714351,A NL185211C (en) 1976-12-27 1977-12-23 PROCESS FOR PREPARING THE METHYL ESTER OF ALFA-L-ASPARTYL-L-PHENYLALANINE.

Country Status (18)

Country Link
JP (1) JPS6050200B2 (en)
AU (1) AU515038B2 (en)
BE (1) BE862258A (en)
BR (1) BR7708632A (en)
CA (1) CA1100487A (en)
CH (1) CH631435A5 (en)
DE (1) DE2757771A1 (en)
DK (1) DK149432C (en)
FR (1) FR2375194A1 (en)
GB (1) GB1546979A (en)
HU (1) HU179735B (en)
IT (1) IT1088938B (en)
MX (1) MX4704E (en)
NL (1) NL185211C (en)
NO (1) NO148069C (en)
SE (1) SE440506B (en)
SU (1) SU884564A3 (en)
ZA (1) ZA777614B (en)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS59219258A (en) * 1983-05-28 1984-12-10 Ajinomoto Co Inc Preparation of alpha-l-aspartyl-l-phenylalanine methyl ester or its hydrochloride
JPS59225152A (en) * 1983-06-02 1984-12-18 Ajinomoto Co Inc Preparation of alpha-l-aspartyl-l-phenylalanine-methyl ester of its hydrochloride
US4618695A (en) * 1983-06-02 1986-10-21 Ajinomoto Co., Inc. Method of preparing methyl ester and its hydrochloride
GB8321802D0 (en) * 1983-08-12 1983-09-14 Erba Farmitalia Aspartame synthesis
JPH07636B2 (en) * 1984-12-17 1995-01-11 三井東圧化学株式会社 Process for producing N-formyl-α-aspartyl phenylalanine
ES8703487A1 (en) * 1984-12-27 1987-03-01 Mitsui Toatsu Chemicals Process for the preparation of alpha-L-aspartyl-L-phenylalanine methyl ester.
AU561384B2 (en) * 1985-03-26 1987-05-07 Mitsui Toatsu Chemicals Inc. Preparation of -l-aspartyl-l-phenylalanine methyl ester or hydrochloride thereof
AU586669B2 (en) * 1985-03-29 1989-07-20 Mitsui Toatsu Chemicals Inc. Preparation process of ```-L-aspartyl-L-phenylalanine methyl ester or hydrochloride thereof
DE3600731A1 (en) * 1986-01-13 1987-07-16 Green Cross Korea METHOD FOR PRODUCING (ALPHA) -L-ASPARTYL-L-PHENYLALANINE METHYLESTER
JPS6383098A (en) * 1986-09-27 1988-04-13 Ajinomoto Co Inc Production of alpha-l-aspartyl-l-phenylalanine or derivative thereof
EP0270345B1 (en) * 1986-12-05 1992-07-22 MITSUI TOATSU CHEMICALS, Inc. Preparation of alpha-l-aspartyl-l-phenyl-alanine methyl ester or hydrohalide thereof
JPH0832719B2 (en) * 1986-12-19 1996-03-29 三井東圧化学株式会社 Method for producing α-L-aspartyl-L-phenylalanine methyl ester having low hygroscopicity
JPS6411999U (en) * 1987-07-13 1989-01-23

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5232371B2 (en) * 1972-07-20 1977-08-20
US3933781A (en) * 1973-11-05 1976-01-20 Monsanto Company Process for the preparation of α-L-aspartyl-L-phenylalanine alkyl esters
JPS5223001A (en) * 1975-08-14 1977-02-21 Ajinomoto Co Inc Process for elimination of formyl group

Also Published As

Publication number Publication date
DE2757771C2 (en) 1988-08-25
SE7714709L (en) 1978-06-28
SE440506B (en) 1985-08-05
BR7708632A (en) 1978-08-22
DK149432B (en) 1986-06-09
FR2375194A1 (en) 1978-07-21
NL185211C (en) 1990-02-16
NO148069B (en) 1983-04-25
NO774440L (en) 1978-06-28
SU884564A3 (en) 1981-11-23
MX4704E (en) 1982-08-04
CH631435A5 (en) 1982-08-13
DK149432C (en) 1987-04-21
AU515038B2 (en) 1981-03-12
JPS5382752A (en) 1978-07-21
JPS6050200B2 (en) 1985-11-07
FR2375194B1 (en) 1984-04-13
DE2757771A1 (en) 1978-07-06
NL7714351A (en) 1978-06-29
BE862258A (en) 1978-06-23
DK577977A (en) 1978-06-28
HU179735B (en) 1982-12-28
GB1546979A (en) 1979-06-06
AU3201477A (en) 1979-06-28
IT1088938B (en) 1985-06-10
NO148069C (en) 1983-08-03
CA1100487A (en) 1981-05-05
ZA777614B (en) 1978-10-25

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Legal Events

Date Code Title Description
BA A request for search or an international-type search has been filed
BB A search report has been drawn up
A85 Still pending on 85-01-01
BC A request for examination has been filed
V4 Discontinued because of reaching the maximum lifetime of a patent

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