NL180749C - PROCESS FOR PREPARING A PHARMACEUTICAL PREPARATION WITH ANTIHISTAMINE ACTION AND ACTION ON THE CARDIOVASCULAR SYSTEM, AND METHOD FOR PREPARING PIPERIDINE DERIVATIVES SUITABLE FOR USE - Google Patents

PROCESS FOR PREPARING A PHARMACEUTICAL PREPARATION WITH ANTIHISTAMINE ACTION AND ACTION ON THE CARDIOVASCULAR SYSTEM, AND METHOD FOR PREPARING PIPERIDINE DERIVATIVES SUITABLE FOR USE

Info

Publication number
NL180749C
NL180749C NL7300838A NL7300838A NL180749C NL 180749 C NL180749 C NL 180749C NL 7300838 A NL7300838 A NL 7300838A NL 7300838 A NL7300838 A NL 7300838A NL 180749 C NL180749 C NL 180749C
Authority
NL
Netherlands
Prior art keywords
preparing
action
pharmaceutical preparation
cardiovascular system
piperidine derivatives
Prior art date
Application number
NL7300838A
Other languages
Dutch (nl)
Other versions
NL180749B (en
NL7300838A (en
Original Assignee
Wyeth John & Brother Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Wyeth John & Brother Ltd filed Critical Wyeth John & Brother Ltd
Publication of NL7300838A publication Critical patent/NL7300838A/xx
Publication of NL180749B publication Critical patent/NL180749B/en
Application granted granted Critical
Publication of NL180749C publication Critical patent/NL180749C/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D211/56—Nitrogen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D211/56—Nitrogen atoms
    • C07D211/58—Nitrogen atoms attached in position 4

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
NL7300838A 1972-01-20 1973-01-19 PROCESS FOR PREPARING A PHARMACEUTICAL PREPARATION WITH ANTIHISTAMINE ACTION AND ACTION ON THE CARDIOVASCULAR SYSTEM, AND METHOD FOR PREPARING PIPERIDINE DERIVATIVES SUITABLE FOR USE NL180749C (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB272072A GB1404003A (en) 1972-01-20 1972-01-20 N-substituted-4-amidopiperidines tetrahydropyridines and pyridines

Publications (3)

Publication Number Publication Date
NL7300838A NL7300838A (en) 1973-07-24
NL180749B NL180749B (en) 1986-11-17
NL180749C true NL180749C (en) 1987-04-16

Family

ID=9744619

Family Applications (1)

Application Number Title Priority Date Filing Date
NL7300838A NL180749C (en) 1972-01-20 1973-01-19 PROCESS FOR PREPARING A PHARMACEUTICAL PREPARATION WITH ANTIHISTAMINE ACTION AND ACTION ON THE CARDIOVASCULAR SYSTEM, AND METHOD FOR PREPARING PIPERIDINE DERIVATIVES SUITABLE FOR USE

Country Status (8)

Country Link
JP (1) JPS59507B2 (en)
BE (1) BE794333A (en)
CA (1) CA984843A (en)
CH (2) CH590840A5 (en)
DE (1) DE2302717A1 (en)
FR (1) FR2181678B1 (en)
GB (1) GB1404003A (en)
NL (1) NL180749C (en)

Families Citing this family (30)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1542137A (en) * 1976-03-12 1979-03-14 Wyeth John & Brother Ltd Process for preparing 3(piperidinoalkyl)indoles
US4146630A (en) * 1976-11-12 1979-03-27 Boehringer Mannheim Gmbh Blood pressure lowering and adrenergic β-receptor inhibiting 3-(4-phenoxymethylpiperidino)-propyl-phenyl ethers
GB1582239A (en) 1976-12-11 1981-01-07 Wyeth John & Brother Ltd Piperidin-4-yl ureas and thioureas
JPS54160371A (en) * 1978-06-02 1979-12-19 Kyowa Hakko Kogyo Co Ltd Novel piperidine derivative and hypotensive agents comprising it
US4246268A (en) * 1979-02-09 1981-01-20 Richardson-Merrell Inc. Neuroleptic-4-(naphthylmethyl)piperidine derivatives
US4329348A (en) 1979-02-26 1982-05-11 Ciba-Geigy Corporation N-Oxacyclic-alkylpiperidines as psychostimulants
US4242347A (en) 1979-06-18 1980-12-30 Ciba-Geigy Corporation Hypotensive indolylalkylpiperidyl guanidines and isoureas
EP0025111B1 (en) * 1979-08-10 1984-07-25 Sandoz Ag 3-aminopropoxyaryl derivatives, their preparation and pharmaceutical compositions containing them
US4432984A (en) * 1980-03-27 1984-02-21 Emile Bouchara Anti-hypertensive benzodioxan derivatives
US4410528A (en) * 1980-05-16 1983-10-18 Kyowa Hakko Kogyo Co., Ltd. Hypotensive piperidine derivatives
DE3025385A1 (en) * 1980-07-04 1982-01-28 Boehringer Mannheim Gmbh, 6800 Mannheim NEW TRICYCLIC ARYL ETHERS, METHOD FOR THE PRODUCTION THEREOF AND MEDICINAL PRODUCTS CONTAINING THESE COMPOUNDS
DE3200304A1 (en) * 1981-01-16 1982-08-26 Sandoz-Patent-GmbH, 7850 Lörrach 3-AMINOPROPOXYARYL DERIVATIVES, THEIR PRODUCTION AND MEDICINAL PRODUCTS CONTAINING THEM
US4359468A (en) * 1981-02-25 1982-11-16 Boehringer Ingelheim Ltd. Antiallergic N-[4-(indolyl)-piperidino-alkyl]-benzimidazolones
MXPA02008770A (en) 2000-03-06 2004-09-10 Acadia Pharm Inc Azacyclic compounds for use in the treatment of serotonin related diseases.
NZ571695A (en) 2001-12-28 2010-02-26 Acadia Pharm Inc Spiroazacyclic compounds as monoamine receptor for modulating 5-HT2A receptor-mediated events
US7253186B2 (en) 2002-06-24 2007-08-07 Carl-Magnus Andersson N-substituted piperidine derivatives as serotonin receptor agents
NZ537522A (en) 2002-06-24 2006-07-28 Acadia Pharm Inc N-substituted piperidine derivatives as serotonin receptor agents
US7538222B2 (en) 2002-06-24 2009-05-26 Acadia Pharmaceuticals, Inc. N-substituted piperidine derivatives as serotonin receptor agents
PT1587789E (en) 2003-01-16 2008-12-16 Acadia Pharm Inc Selective serotonin 2a/2c receptor inverse agonists as therapeutics for neurodegenerative diseases
US20050261278A1 (en) 2004-05-21 2005-11-24 Weiner David M Selective serotonin receptor inverse agonists as therapeutics for disease
US7820695B2 (en) 2004-05-21 2010-10-26 Acadia Pharmaceuticals, Inc. Selective serotonin receptor inverse agonists as therapeutics for disease
US7790899B2 (en) 2004-09-27 2010-09-07 Acadia Pharmaceuticals, Inc. Synthesis of N-(4-fluorobenzyl)-N-(1-methylpiperidin-4-yl)-N′-(4-(2-methylpropyloxy)phenylmethyl)carbamide and its tartrate salt and crystalline forms
BRPI0516063A (en) 2004-09-27 2008-08-19 Acadia Pharm Inc Synthesis of n- (4-fluorbenzyl) -N- (1-methylpiperidin-4-yl) -N '- (4- (2-methylpyropyloxy) phenylmethyl) carbamide and its tartrate salt and crystalline forms
DK2134330T3 (en) 2007-03-19 2013-08-05 Acadia Pharm Inc COMBINATIONS OF 5-HT2A-INVERSE AGONISTS AND ANTAGONISTS WITH ANTI-SUBSTANCES
PT3325444T (en) 2015-07-20 2021-09-22 Acadia Pharm Inc Methods for preparing n-(4-fluorobenzyl)-n-(1-methylpiperidin-4-yl)-n'-(4-(2-methylpropyloxy)phenylmethyl)carbamide and its tartrate salt and polymorphic form c
WO2017165635A1 (en) 2016-03-25 2017-09-28 Acadia Pharmaceuticals Inc. Combination of pimavanserin and cytochrome p450 modulators
US10953000B2 (en) 2016-03-25 2021-03-23 Acadia Pharmaceuticals Inc. Combination of pimavanserin and cytochrome P450 modulators
US11464768B2 (en) 2016-12-20 2022-10-11 Acadia Pharmaceuticals Inc. Pimavanserin alone or in combination for use in the treatment of Alzheimer's disease psychosis
WO2018200977A1 (en) 2017-04-28 2018-11-01 Acadia Pharmaceuticals Inc. Pimavanserin for treating impulse control disorder
US20210077479A1 (en) 2017-08-30 2021-03-18 Acadia Pharmaceuticals Inc. Formulations of pimavanserin

Also Published As

Publication number Publication date
FR2181678A1 (en) 1973-12-07
CA984843A (en) 1976-03-02
DE2302717A1 (en) 1973-07-26
JPS4880569A (en) 1973-10-29
GB1404003A (en) 1975-08-28
CH590840A5 (en) 1977-08-31
NL180749B (en) 1986-11-17
FR2181678B1 (en) 1976-09-03
BE794333A (en) 1973-07-19
JPS59507B2 (en) 1984-01-07
NL7300838A (en) 1973-07-24
CH595347A5 (en) 1978-02-15

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Legal Events

Date Code Title Description
BB A search report has been drawn up
BC A request for examination has been filed
A85 Still pending on 85-01-01
V1 Lapsed because of non-payment of the annual fee