NL176168B - METHOD FOR THE PREPARATION RESPECTIVELY MANUFACTURE OF A PHARMACEUTICAL PREPARATION AND METHOD FOR THE PREPARATION OF USEFUL NEW SUBSTITUTED 1-(4-AMINOPHENYL)-2-AMINO-ETHANOL DERIVATIVES WHICH, EXCEPT AN ANALGETIC, UTERUS SPASMOLYTIC AND ANTISPASTIC ACTIVITY, HAVE RELATIVE STRIPES IN PARTICULAR HAVE A BETA2 MIMETIC AND/OR BETA1 BLOCKING ACTIVITY. - Google Patents

METHOD FOR THE PREPARATION RESPECTIVELY MANUFACTURE OF A PHARMACEUTICAL PREPARATION AND METHOD FOR THE PREPARATION OF USEFUL NEW SUBSTITUTED 1-(4-AMINOPHENYL)-2-AMINO-ETHANOL DERIVATIVES WHICH, EXCEPT AN ANALGETIC, UTERUS SPASMOLYTIC AND ANTISPASTIC ACTIVITY, HAVE RELATIVE STRIPES IN PARTICULAR HAVE A BETA2 MIMETIC AND/OR BETA1 BLOCKING ACTIVITY.

Info

Publication number
NL176168B
NL176168B NLAANVRAGE7316139,A NL7316139A NL176168B NL 176168 B NL176168 B NL 176168B NL 7316139 A NL7316139 A NL 7316139A NL 176168 B NL176168 B NL 176168B
Authority
NL
Netherlands
Prior art keywords
preparation
activity
beta1
analgetic
spasmolytic
Prior art date
Application number
NLAANVRAGE7316139,A
Other languages
Dutch (nl)
Other versions
NL176168C (en
NL7316139A (en
Original Assignee
Thomae Gmbh Dr K
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from DE2261914A external-priority patent/DE2261914C3/en
Priority claimed from DE19732345442 external-priority patent/DE2345442C2/en
Priority claimed from DE19732351281 external-priority patent/DE2351281C3/en
Priority claimed from DE2354961A external-priority patent/DE2354961C2/en
Application filed by Thomae Gmbh Dr K filed Critical Thomae Gmbh Dr K
Publication of NL7316139A publication Critical patent/NL7316139A/xx
Publication of NL176168B publication Critical patent/NL176168B/en
Application granted granted Critical
Publication of NL176168C publication Critical patent/NL176168C/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C215/00—Compounds containing amino and hydroxy groups bound to the same carbon skeleton
    • C07C215/02—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton
    • C07C215/22—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being unsaturated
    • C07C215/28—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being unsaturated and containing six-membered aromatic rings
    • C07C215/30—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being unsaturated and containing six-membered aromatic rings containing hydroxy groups and carbon atoms of six-membered aromatic rings bound to the same carbon atom of the carbon skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
    • C07D263/02—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings
    • C07D263/04—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C213/00—Preparation of compounds containing amino and hydroxy, amino and etherified hydroxy or amino and esterified hydroxy groups bound to the same carbon skeleton
    • C07C213/02—Preparation of compounds containing amino and hydroxy, amino and etherified hydroxy or amino and esterified hydroxy groups bound to the same carbon skeleton by reactions involving the formation of amino groups from compounds containing hydroxy groups or etherified or esterified hydroxy groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C255/00—Carboxylic acid nitriles
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C271/00—Derivatives of carbamic acids, i.e. compounds containing any of the groups, the nitrogen atom not being part of nitro or nitroso groups
    • C07C271/06—Esters of carbamic acids
    • C07C271/08—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms
    • C07C271/10—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms with the nitrogen atoms of the carbamate groups bound to hydrogen atoms or to acyclic carbon atoms
    • C07C271/22—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms with the nitrogen atoms of the carbamate groups bound to hydrogen atoms or to acyclic carbon atoms to carbon atoms of hydrocarbon radicals substituted by carboxyl groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D317/00—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D317/08—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
    • C07D317/44—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D317/46—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems condensed with one six-membered ring
    • C07D317/48—Methylenedioxybenzenes or hydrogenated methylenedioxybenzenes, unsubstituted on the hetero ring
    • C07D317/50—Methylenedioxybenzenes or hydrogenated methylenedioxybenzenes, unsubstituted on the hetero ring with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to atoms of the carbocyclic ring
    • C07D317/58—Radicals substituted by nitrogen atoms
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Pain & Pain Management (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
NLAANVRAGE7316139,A 1972-12-18 1973-11-26 PROCEDURE FOR THE PREPARATION OR MANUFACTURE OF A PHARMACEUTICAL PREPARATION AND METHOD FOR THE PREPARATION OF USEFUL NEW SUBSTITUTED 1-(4-AMINOPHENYL)-2-AMINO-ETHANOL DERIVATIVES WHICH, EXCEPT AN ANALGETIC, UTERUS SPASMOLYTIC AND ANTI-SPASTIC ACTIVITY, HAVE RELATIVE STRIPES IN PARTICULAR HAVE A BETA2 MIMETIC AND/OR BETA1 BLOCKING ACTIVITY. NL176168C (en)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
DE2261914A DE2261914C3 (en) 1972-12-18 1972-12-18 Amino-phenyl-ethanolamines and their acid addition salts, processes for their production and pharmaceuticals
DE19732345442 DE2345442C2 (en) 1973-09-08 1973-09-08 d- and l-phenylethanolamines and their salts, manufacturing processes and drugs based on them
DE19732351281 DE2351281C3 (en) 1973-10-12 1973-10-12 Aminophenylethanolamine derivatives, their production and use
DE2354961A DE2354961C2 (en) 1973-11-02 1973-11-02 Process for the preparation of aminophenylethanolamines

Publications (3)

Publication Number Publication Date
NL7316139A NL7316139A (en) 1974-06-20
NL176168B true NL176168B (en) 1984-10-01
NL176168C NL176168C (en) 1985-03-01

Family

ID=27431596

Family Applications (1)

Application Number Title Priority Date Filing Date
NLAANVRAGE7316139,A NL176168C (en) 1972-12-18 1973-11-26 PROCEDURE FOR THE PREPARATION OR MANUFACTURE OF A PHARMACEUTICAL PREPARATION AND METHOD FOR THE PREPARATION OF USEFUL NEW SUBSTITUTED 1-(4-AMINOPHENYL)-2-AMINO-ETHANOL DERIVATIVES WHICH, EXCEPT AN ANALGETIC, UTERUS SPASMOLYTIC AND ANTI-SPASTIC ACTIVITY, HAVE RELATIVE STRIPES IN PARTICULAR HAVE A BETA2 MIMETIC AND/OR BETA1 BLOCKING ACTIVITY.

Country Status (20)

Country Link
JP (1) JPS5811852B2 (en)
KR (1) KR850001916B1 (en)
BG (1) BG21209A3 (en)
CA (1) CA1027955A (en)
CH (2) CH614188A5 (en)
DD (1) DD111574A5 (en)
DK (1) DK150502C (en)
FI (1) FI62052C (en)
FR (1) FR2210414B1 (en)
GB (1) GB1445740A (en)
HK (1) HK6680A (en)
HU (1) HU168701B (en)
IE (1) IE39065B1 (en)
IL (1) IL43837A (en)
MY (1) MY8800145A (en)
NL (1) NL176168C (en)
NO (1) NO137782C (en)
PL (1) PL97194B1 (en)
RO (1) RO63025A (en)
SE (1) SE409700B (en)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2430486A1 (en) * 1978-07-07 1980-02-01 Oreal Disinfectant deodorant stick for hanging in WC - is in cage within sealed cartridge which is removed by tearing strip defined by rupture lines
NL8105170A (en) * 1980-12-10 1982-07-01 Thomae Gmbh Dr K NEW PHENYL ALKYLAMINS, METHOD FOR THE PREPARATION THEREOF AND THE USE THEREOF AS MEDICINES.
FR2515177A1 (en) * 1981-10-28 1983-04-29 Lafon Labor 1-Amino:phenyl 2-isopropyl or tert.butyl-amino 1-ethanol derivs. - used as antidepressants, sedatives, vasodilators and hypotensives, without hyper:reactivity and excitation side effects
GB8426191D0 (en) * 1984-10-17 1984-11-21 Glaxo Holdings Ltd Chemical compounds
US4943591A (en) * 1984-10-17 1990-07-24 Glaxo Group Limited Dichloroaniline derivatives
DE3678252D1 (en) * 1985-10-17 1991-04-25 American Cyanamid Co ANTHRANILONITRILE DERIVATIVES AND RELATED COMPOUNDS AS USEFUL SUBSTANCES FOR ACCELERATING GROWTH, FOR IMPROVING THE QUALITY OF FOOD AND FOR INCREASING THE MEAT / FAT RATIO IN WARM BLOODED ANIMALS.
US4863959A (en) * 1985-10-17 1989-09-05 American Cyanamid Company Anthranilonitrile derivatives as useful agents for promoting growth, improving feed efficiency, and for increasing the lean meat to fat ratio of warm-blooded animals
GB8603475D0 (en) * 1986-02-12 1986-03-19 Glaxo Group Ltd Chemical compounds
US4959381A (en) * 1987-02-10 1990-09-25 Glaxo Group Limited Pyridine compounds which have useful activity associated with reversible air ways obstruction
GB8703007D0 (en) * 1987-02-10 1987-03-18 Glaxo Group Ltd Chemical compounds
US8158814B2 (en) * 2003-08-29 2012-04-17 Mitsui Chemicals, Inc. Insecticide for agricultural or horticultural use and method of use thereof
GB0604822D0 (en) * 2006-03-09 2006-04-19 Arakis Ltd The treatment of inflammatory disorders and pain
CN100497296C (en) * 2006-07-07 2009-06-10 沈阳药科大学 Novel optical activity phenylethanolamine compounds and preparation method thereof
GB201714736D0 (en) 2017-09-13 2017-10-25 Atrogi Ab New compounds and uses
GB201714734D0 (en) * 2017-09-13 2017-10-25 Atrogi Ab New compounds and uses

Also Published As

Publication number Publication date
GB1445740A (en) 1976-08-11
HU168701B (en) 1976-06-28
FR2210414A1 (en) 1974-07-12
FR2210414B1 (en) 1977-01-28
NO137782B (en) 1978-01-16
HK6680A (en) 1980-03-07
NO137782C (en) 1978-04-26
NL176168C (en) 1985-03-01
IE39065B1 (en) 1978-08-02
CH605622A5 (en) 1978-10-13
IL43837A (en) 1977-02-28
BG21209A3 (en) 1976-03-20
PL97194B1 (en) 1978-02-28
DD111574A5 (en) 1975-02-20
AU6369373A (en) 1975-06-19
NL7316139A (en) 1974-06-20
IL43837A0 (en) 1974-03-14
JPS4994640A (en) 1974-09-09
RO63025A (en) 1978-12-15
KR850001916B1 (en) 1985-12-31
CH614188A5 (en) 1979-11-15
FI62052C (en) 1982-11-10
FI62052B (en) 1982-07-30
KR830000207A (en) 1983-03-30
CA1027955A (en) 1978-03-14
SE409700B (en) 1979-09-03
DK150502B (en) 1987-03-16
IE39065L (en) 1974-06-18
MY8800145A (en) 1988-12-31
JPS5811852B2 (en) 1983-03-04
DK150502C (en) 1987-10-26

Similar Documents

Publication Publication Date Title
NL176168B (en) METHOD FOR THE PREPARATION RESPECTIVELY MANUFACTURE OF A PHARMACEUTICAL PREPARATION AND METHOD FOR THE PREPARATION OF USEFUL NEW SUBSTITUTED 1-(4-AMINOPHENYL)-2-AMINO-ETHANOL DERIVATIVES WHICH, EXCEPT AN ANALGETIC, UTERUS SPASMOLYTIC AND ANTISPASTIC ACTIVITY, HAVE RELATIVE STRIPES IN PARTICULAR HAVE A BETA2 MIMETIC AND/OR BETA1 BLOCKING ACTIVITY.
FR2340318A1 (en) NEW FORMS OF TRANSITIONAL DRUG PRECURSORS, OF THE XANTHINE DERIVATIVE TYPE.
NL141187B (en) PROCESS FOR THE PREPARATION OF A MEDICINAL PRODUCT WITH ANALGETIC AND ANTI-INFLAMMATORY ACTION, PREPARED MEDICINAL PRODUCT THEREOF, AND PROCESS FOR PREPARING MEDICINAL COMPOUNDS.
NL7712559A (en) PIPERIDINE DERIVATIVES, METHODS FOR PREPARING THEM AND PHARMACEUTICAL PREPARATIONS CONTAINING THESE COMPOUNDS.
NL170539C (en) METHOD FOR PREPARING NEW ISOFLAVONES, METHOD FOR PREPARING A FEED, A FEED PRE-MIXTURE OR THE LIKE, A METHOD FOR PREPARING A THERAPEUTIC PREPARATION AND ARTICLES MADE THEREFORE.
NL7513854A (en) METHOD OF PREPARATION OF A MEDICINAL PRODUCT WITH BRONCHOSPASMOLYTIC ACTION CONTAINING ONE OR SOME DERIVATIVES OF 2-AMINO-1- (3,5-DIHYDROXYPHENYL) -ETHANOL AND THE USE OF THIS METHODS OF METHODS-BRONCHOSPASMOLYTIC ACTION AND PROCEDURE FOR PREPARING NOSPICID 2-AMINO-1- (3,5-DIHYDROXYPHENYL) -ETHANOL DERIVATIVES.
NL7603012A (en) NITROFURYLPYRAZOLE DERIVATIVES, METHODS FOR PREPARING THEM, AND MEDICINAL PROPERTIES CONTAINING THESE COMPOUNDS.
NL160816C (en) PROCESS FOR THE PREPARATION OF 4,4-DICHLOR OR 4,4-DI-BROMOOM PYRAZOLONES, PROCESS FOR PREPARATION OF A PREPARATION AND PREPARATION THEREFORE OBTAINED.
NL170736C (en) PROCESS FOR THE PREPARATION OF A PHARMACEUTICAL PREPARATION WITH ANTIBACTERIAL ACTION, A FORMED PHARMACEUTICAL PREPARATION AND A PROCESS FOR THE PREPARATION OF 2-DESOXYSTREPTAMINE AMINOGLYCOSIDES.
NL7600945A (en) PROCEDURE FOR PREPARING OXIM ETHERS, AS WELL AS PROCEDURE FOR PREPARING A MEDICINAL PRODUCT WITH INCLUDING LOCAL ANALGETIC AND SPASMOLYTIC ACTION.
NL162897B (en) METHOD FOR PREPARING A BLENDED MEDICINAL PRODUCT ON BETA-ADRENERGIC RECEPTORS, FORMED MEDICINAL PRODUCT AND METHOD FOR PREPARING THE ACTIVE COMPOUND.
TR17686A (en) TETRASUEBSTITUEE AREAS, THE METHODS FOR MANUFACTURING THEM AND THEIR USE AS HERBISIDES
NL170283B (en) METHOD FOR PREPARING COMPOUNDS WITH ANALGETIC AND ANTI-INFLAMMATIVE ACTIVITY, AND PREPARED MEDICINES PRODUCED THEREFOR
FI49509C (en) Process for the preparation of pharmacologically active 5,10-substituted 5,10-dihydro-11H-dibenzo [b, e] -1,4] deazepin-11-ones and their salts.
NL7709007A (en) METHOD FOR PREPARING NEW COMPOUNDS WITH ANTI-BACTERIAL ACTION, AND FORMED PHARMACEUTICAL PREPARATIONS CONTAINING THESE COMPOUNDS
NL7705839A (en) PROCESS FOR PREPARING A MEDICINAL PRODUCT AGAINST EYE DISEASES AND THE MEDICINAL PRODUCT THEREFORE.
NL176173B (en) PROCESS FOR PREPARING A PHARMACEUTICAL PREPARATION WITH ANALGETIC AND ANTI-INFLAMMATORIC ACTION AND THE USE THEREOF NEW AROYL-THIOPHENE-ACETIC ACID DERIVATIVES.
NL178591C (en) METHOD FOR PREPARING A 6-DESOXYTETRACYCLINE, AND METHOD FOR PREPARING OR MANUFACTURING A THERAPEUTIC PREPARATION CONTAINING SUCH TETRACYCLINE
NL7710325A (en) PROCESS FOR THE PREPARATION OF NEW QINOLINE DERIVATIVES AND PROCESS FOR THE PREPARATION OF PHARMACEUTICAL PREPARATIONS.
CH557150A (en) METHOD FOR MANUFACTURING A TASTE-ENHANCING AGENT, TASTE-ENHANCING AGENT SO MANUFACTURED AND THE USE THEREOF.
NL161439C (en) METHOD FOR THE PREPARATION OF PHARMACEUTICAL PREPARATIONS WITH NERVOUS ACTIVITY CONTAINING A 5-(3-DIMETHYLAMINO-PROPYLIDENE)-5H-DIBENZO A,D CYCLOHEPTENE-N-OXIDE, AND METHOD FOR THE PREPARATION OF SUITABLE COMPOUNDS THEREOF.
NL161754B (en) METHOD FOR THE PREPARATION OF A PHARMACEUTICAL PREPARATION WITH BETA-ADRENERGIC BLOCKING ACTIVITY, AND PHARMACEUTICAL ARTICLES AND METHOD FOR PREPARING HETEROCYCLIC AMINOPROPROPIC PRODUCT.
NO772996L (en) 2-AMINO-4H-PYRANES, PROCEDURES FOR THEIR MANUFACTURE AND THEIR USE AS MEDICINES.
NL150780B (en) PROCESS FOR THE PREPARATION OF AMPHETAMINE DERIVATIVES WITH ANOREXIGENIC ACTION, PROCESS FOR THE PREPARATION OF A MEDICINAL PRODUCT WITH ANOREXIGENIC ACTION AND FORMED MEDICINAL PRODUCT.
DK480177A (en) 1- (4-PHENOXY-PHENYL) -1,3,5-TRIAZINDERIAZINE DERIVATIVES PROCEDURES FOR THE MANUFACTURE OF IT AND THEIR USE AS MEDICINES

Legal Events

Date Code Title Description
BA A request for search or an international-type search has been filed
BB A search report has been drawn up
BC A request for examination has been filed
A85 Still pending on 85-01-01
V4 Discontinued because of reaching the maximum lifetime of a patent