NL175522C - Werkwijze ter bereiding van peptiden, onder toepassing van een carbodiimidereagens en een n-hydroximideverbinding. - Google Patents

Werkwijze ter bereiding van peptiden, onder toepassing van een carbodiimidereagens en een n-hydroximideverbinding.

Info

Publication number
NL175522C
NL175522C NLAANVRAGE7303589,A NL7303589A NL175522C NL 175522 C NL175522 C NL 175522C NL 7303589 A NL7303589 A NL 7303589A NL 175522 C NL175522 C NL 175522C
Authority
NL
Netherlands
Prior art keywords
hydroximide
carbodiimid
reagents
compound
preparing peptides
Prior art date
Application number
NLAANVRAGE7303589,A
Other languages
English (en)
Dutch (nl)
Other versions
NL175522B (nl
NL7303589A (xx
Original Assignee
Takeda Chemical Industries Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from JP47026467A external-priority patent/JPS5025442B2/ja
Priority claimed from JP2874072A external-priority patent/JPS5725540B2/ja
Priority claimed from JP2874172A external-priority patent/JPS5647175B2/ja
Application filed by Takeda Chemical Industries Ltd filed Critical Takeda Chemical Industries Ltd
Publication of NL7303589A publication Critical patent/NL7303589A/xx
Publication of NL175522B publication Critical patent/NL175522B/xx
Application granted granted Critical
Publication of NL175522C publication Critical patent/NL175522C/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/08—Tripeptides
    • C07K5/0821—Tripeptides with the first amino acid being heterocyclic, e.g. His, Pro, Trp
    • C07K5/0825—Tripeptides with the first amino acid being heterocyclic, e.g. His, Pro, Trp and Glp-amino acid; Derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/18—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
    • C07D207/22—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D207/24—Oxygen or sulfur atoms
    • C07D207/26—2-Pyrrolidones
    • C07D207/273—2-Pyrrolidones with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to other ring carbon atoms
    • C07D207/277—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D207/28—2-Pyrrolidone-5- carboxylic acids; Functional derivatives thereof, e.g. esters, nitriles
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/06—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length using protecting groups or activating agents
    • C07K1/08—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length using protecting groups or activating agents using activating agents
    • C07K1/084—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length using protecting groups or activating agents using activating agents containing nitrogen
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/665—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans derived from pro-opiomelanocortin, pro-enkephalin or pro-dynorphin
    • C07K14/695—Corticotropin [ACTH]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/08—Tripeptides
    • C07K5/0802—Tripeptides with the first amino acid being neutral
    • C07K5/0804—Tripeptides with the first amino acid being neutral and aliphatic
    • C07K5/0806—Tripeptides with the first amino acid being neutral and aliphatic the side chain containing 0 or 1 carbon atoms, i.e. Gly, Ala
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S930/00—Peptide or protein sequence
    • Y10S930/01—Peptide or protein sequence
    • Y10S930/13—Luteinizing hormone-releasing hormone; related peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Molecular Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Analytical Chemistry (AREA)
  • Peptides Or Proteins (AREA)
NLAANVRAGE7303589,A 1972-03-14 1973-03-14 Werkwijze ter bereiding van peptiden, onder toepassing van een carbodiimidereagens en een n-hydroximideverbinding. NL175522C (nl)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP47026467A JPS5025442B2 (xx) 1972-03-14 1972-03-14
JP2874072A JPS5725540B2 (xx) 1972-03-21 1972-03-21
JP2874172A JPS5647175B2 (xx) 1972-03-21 1972-03-21

Publications (3)

Publication Number Publication Date
NL7303589A NL7303589A (xx) 1973-09-18
NL175522B NL175522B (nl) 1984-06-18
NL175522C true NL175522C (nl) 1984-11-16

Family

ID=27285414

Family Applications (1)

Application Number Title Priority Date Filing Date
NLAANVRAGE7303589,A NL175522C (nl) 1972-03-14 1973-03-14 Werkwijze ter bereiding van peptiden, onder toepassing van een carbodiimidereagens en een n-hydroximideverbinding.

Country Status (10)

Country Link
US (1) US3870694A (xx)
AU (1) AU466760B2 (xx)
CA (1) CA998997A (xx)
CH (1) CH581097A5 (xx)
DK (1) DK129088B (xx)
FR (1) FR2176009B1 (xx)
GB (1) GB1374379A (xx)
HU (1) HU170340B (xx)
NL (1) NL175522C (xx)
SE (1) SE405966B (xx)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4126628A (en) * 1977-03-28 1978-11-21 Canadian Patents And Development Limited Acylation of amino acids
US4581168A (en) * 1983-02-21 1986-04-08 Sanofi Synthesis of hpGRF (Somatocrinin) in liquid phase and intermediate peptides
GB2144128B (en) * 1983-07-29 1986-11-26 Sanyo Machine Works The tripeptide eisenin and carcinostatic compositions having an immunopotentiating carcinostatic effect which contain it
US5502165A (en) * 1994-04-04 1996-03-26 Merck & Co., Inc. Process for peptide segment condensation
US6120491A (en) * 1997-11-07 2000-09-19 The State University Rutgers Biodegradable, anionic polymers derived from the amino acid L-tyrosine
AU761458B2 (en) 1998-04-13 2003-06-05 Rutgers, The State University The construction of copolymer libraries
US7521061B2 (en) * 1999-12-31 2009-04-21 Rutgers, The State University Of New Jersey Pharmaceutical formulation for regulating the timed release of biologically active compounds based on a polymer matrix
PL3002294T3 (pl) * 2006-06-13 2018-08-31 Helix Biomedix, Inc. Fragmenty peptydowe do indukowania syntezy białek macierzy zewnątrzkomórkowej

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1593842A1 (de) * 1967-01-05 1970-08-27 Hoechst Ag Verfahren zur Herstellung von Peptiden

Also Published As

Publication number Publication date
NL175522B (nl) 1984-06-18
AU466760B2 (en) 1975-11-06
SE405966B (sv) 1979-01-15
CH581097A5 (xx) 1976-10-29
FR2176009A1 (xx) 1973-10-26
US3870694A (en) 1975-03-11
NL7303589A (xx) 1973-09-18
FR2176009B1 (xx) 1977-08-12
AU5308773A (en) 1974-09-12
CA998997A (en) 1976-10-26
DK129088B (da) 1974-08-19
HU170340B (xx) 1977-05-28
GB1374379A (en) 1974-11-20

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Legal Events

Date Code Title Description
BC A request for examination has been filed
V4 Discontinued because of reaching the maximum lifetime of a patent