NL172744B - METHOD FOR PREPARING BASIC SUBSTITUTED PHENYLACETONITRILE COMPOUNDS AND MEDICINAL CONTAINERS WITH A CORONARY FLOW PROMOTING ACTIVITY - Google Patents

METHOD FOR PREPARING BASIC SUBSTITUTED PHENYLACETONITRILE COMPOUNDS AND MEDICINAL CONTAINERS WITH A CORONARY FLOW PROMOTING ACTIVITY

Info

Publication number
NL172744B
NL172744B NL7116577A NL7116577A NL172744B NL 172744 B NL172744 B NL 172744B NL 7116577 A NL7116577 A NL 7116577A NL 7116577 A NL7116577 A NL 7116577A NL 172744 B NL172744 B NL 172744B
Authority
NL
Netherlands
Prior art keywords
promoting activity
coronary flow
flow promoting
preparing basic
basic substituted
Prior art date
Application number
NL7116577A
Other languages
Dutch (nl)
Other versions
NL172744C (en
NL7116577A (en
Original Assignee
Knoll Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Knoll Ag filed Critical Knoll Ag
Publication of NL7116577A publication Critical patent/NL7116577A/xx
Publication of NL172744B publication Critical patent/NL172744B/en
Application granted granted Critical
Publication of NL172744C publication Critical patent/NL172744C/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C255/00—Carboxylic acid nitriles

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
NL7116577A 1970-12-05 1971-12-02 METHOD FOR PREPARING BASIC SUBSTITUTED PHENYLACETONITRILE COMPOUNDS AND MEDICINAL CONTAINERS WITH A CORONARY FLOW PROMOTING ACTIVITY NL172744C (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19702059923 DE2059923C3 (en) 1970-12-05 1970-12-05 1-a-Isopropyl-o - [(N-methyl-N-homoveratryl) v-aminopropyl] -3,4-dimethoxyphenylacetonitrile, process for its preparation and pharmaceuticals containing it

Publications (3)

Publication Number Publication Date
NL7116577A NL7116577A (en) 1972-06-07
NL172744B true NL172744B (en) 1983-05-16
NL172744C NL172744C (en) 1983-10-17

Family

ID=5790091

Family Applications (1)

Application Number Title Priority Date Filing Date
NL7116577A NL172744C (en) 1970-12-05 1971-12-02 METHOD FOR PREPARING BASIC SUBSTITUTED PHENYLACETONITRILE COMPOUNDS AND MEDICINAL CONTAINERS WITH A CORONARY FLOW PROMOTING ACTIVITY

Country Status (8)

Country Link
AT (1) AT305262B (en)
BE (1) BE776218A (en)
CH (1) CH565748A5 (en)
DE (1) DE2059923C3 (en)
FR (1) FR2116564B1 (en)
GB (1) GB1367677A (en)
NL (1) NL172744C (en)
YU (2) YU35346B (en)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3034221A1 (en) * 1980-09-11 1982-04-22 Basf Ag, 6700 Ludwigshafen METHOD FOR PRODUCING BASICLY SUBSTITUTED PHENYL ACETONITRILE
DE3144150A1 (en) 1981-04-10 1982-12-09 Basf Ag, 6700 Ludwigshafen (OMEGA) -CYAN-1, (OMEGA) -DIPHENYL-AZAALKAN DERIVATIVES, THEIR PRODUCTION AND THE MEDICINAL PRODUCTS CONTAINING THEM
DE3138488A1 (en) * 1981-09-28 1983-04-14 Knoll Ag, 6700 Ludwigshafen USE OF BASICLY SUBSTITUTED PHENYL ACETONE RITRILES IN THE PREVENTIVE FIGHT AGAINST DISEASES AND AGENTS THEREFOR
DE3344755A1 (en) * 1983-12-10 1985-06-20 Basf Ag, 6700 Ludwigshafen 1,7-DIPHENYL-3-METHYLAZA-7-CYAN-8-METHYL-NONANES FOR USE IN THE FIGHT AGAINST DISEASES
DE3635930A1 (en) * 1986-10-22 1988-04-28 Basf Ag ACTIVE SUBSTANCES FOR TUMOR TREATMENT
DE3603660C2 (en) * 1986-02-06 1994-09-15 Fresenius Ag Improved peritoneal dialysis
DE4203547A1 (en) * 1992-02-07 1993-08-12 Knoll Ag METHOD FOR RACEMAT SEPARATION OF VERAPAMIL
GB9319918D0 (en) * 1993-09-27 1993-11-10 Chiros Ltd Chiral compounds and their preparation
US5910601A (en) * 1994-09-26 1999-06-08 Darwin Discovery Limited Chiral nitriles, their preparation and their use for the manufacture of verapamil and analogues
US5892093A (en) * 1996-02-08 1999-04-06 Darwin Discovery Limited Resolution
AU705865B2 (en) * 1996-02-08 1999-06-03 Darwin Discovery Limited Resolution of 4-cyano-4-(3,4-dimethoxyphenyl) -5-methylhexanoic acid
WO1997044025A1 (en) * 1996-05-23 1997-11-27 G.D. Searle & Co. Pharmaceutical compositions containing non-racemic verapamil and process for optimizing the pharmaceutical activity of r- and s-verapamil
US5859279A (en) * 1996-09-10 1999-01-12 Darwin Discovery Limited Compound and process
GB9618835D0 (en) * 1996-09-10 1996-10-23 Chiroscience Ltd Process
WO2000055122A1 (en) * 1999-03-16 2000-09-21 Eisai Co., Ltd. Nitrile derivatives
AU770599B2 (en) 1999-07-06 2004-02-26 Methylgene Inc. Sulfonamidomethyl phosphonate inhibitors of beta-lactamase
US6884791B2 (en) 1999-07-06 2005-04-26 Methylgene, Inc. Inhibitors of β-lactamase
SI2170050T1 (en) 2007-06-20 2014-12-31 Milestone Pharmaceuticals Inc. Short acting phenylalkylamine calcium channel blockers and uses thereof
WO2016181292A1 (en) 2015-05-12 2016-11-17 Piramal Enterprises Limited A process for the preparation of verapamil hydrochloride

Also Published As

Publication number Publication date
YU302371A (en) 1980-06-30
NL172744C (en) 1983-10-17
DE2059923B2 (en) 1978-05-18
YU35346B (en) 1980-12-31
AT305262B (en) 1973-02-26
CH565748A5 (en) 1975-08-29
DE2059923C3 (en) 1979-01-25
FR2116564A1 (en) 1972-07-13
YU35348B (en) 1980-12-31
NL7116577A (en) 1972-06-07
DE2059923A1 (en) 1972-06-15
GB1367677A (en) 1974-09-18
YU21879A (en) 1980-06-30
FR2116564B1 (en) 1975-03-14
BE776218A (en) 1972-06-05

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