NL166028B - PROCESS FOR PREPARING A 4'-DEMETHYLEPIPODO-PHYLLOTOXINE-BETA-D-GLUCOSIDE AND PROCESS FOR PREPARING A PHARMACEUTICAL PREPARATION FOR PATHOLOGICAL PROCESSES COVERED ATTENDED AND MEAT-PREPARED PREPARATELY. METHOD. - Google Patents

PROCESS FOR PREPARING A 4'-DEMETHYLEPIPODO-PHYLLOTOXINE-BETA-D-GLUCOSIDE AND PROCESS FOR PREPARING A PHARMACEUTICAL PREPARATION FOR PATHOLOGICAL PROCESSES COVERED ATTENDED AND MEAT-PREPARED PREPARATELY. METHOD.

Info

Publication number
NL166028B
NL166028B NL6901619.A NL6901619A NL166028B NL 166028 B NL166028 B NL 166028B NL 6901619 A NL6901619 A NL 6901619A NL 166028 B NL166028 B NL 166028B
Authority
NL
Netherlands
Prior art keywords
preparing
preparately
phyllotoxine
demethylepipodo
attended
Prior art date
Application number
NL6901619.A
Other languages
Dutch (nl)
Other versions
NL6901619A (en
NL166028C (en
Original Assignee
Sandoz Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sandoz Ag filed Critical Sandoz Ag
Publication of NL6901619A publication Critical patent/NL6901619A/xx
Publication of NL166028B publication Critical patent/NL166028B/en
Application granted granted Critical
Publication of NL166028C publication Critical patent/NL166028C/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H13/00—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids
    • C07H13/02—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids by carboxylic acids
    • C07H13/04—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids by carboxylic acids having the esterifying carboxyl radicals attached to acyclic carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C51/00—Preparation of carboxylic acids or their salts, halides or anhydrides
    • C07C51/54—Preparation of carboxylic acid anhydrides
    • C07C51/56—Preparation of carboxylic acid anhydrides from organic acids, their salts, their esters or their halides, e.g. by carboxylation
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H13/00—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids
    • C07H13/02—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids by carboxylic acids
    • C07H13/08—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids by carboxylic acids having the esterifying carboxyl radicals directly attached to carbocyclic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H13/00—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids
    • C07H13/12—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids by acids having the group -X-C(=X)-X-, or halides thereof, in which each X means nitrogen, oxygen, sulfur, selenium or tellurium, e.g. carbonic acid, carbamic acid
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
    • C07H17/04—Heterocyclic radicals containing only oxygen as ring hetero atoms
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Saccharide Compounds (AREA)
NL6901619.A 1968-02-27 1969-01-31 PROCESS FOR PREPARING A 4'-DEMETHYLEPIPODO-PHYLLOTOXINE-BETA-D-GLUCOSIDE AND PROCESS FOR PREPARING A PHARMACEUTICAL PREPARATION FOR PATHOLOGICAL PROCESSES COVERED ATTENDED AND MEAT-PREPARED PREPARATELY. METHOD. NL166028C (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH284568A CH514578A (en) 1968-02-27 1968-02-27 Process for the production of glucosides

Publications (3)

Publication Number Publication Date
NL6901619A NL6901619A (en) 1969-08-29
NL166028B true NL166028B (en) 1981-01-15
NL166028C NL166028C (en) 1981-06-15

Family

ID=4242875

Family Applications (1)

Application Number Title Priority Date Filing Date
NL6901619.A NL166028C (en) 1968-02-27 1969-01-31 PROCESS FOR PREPARING A 4'-DEMETHYLEPIPODO-PHYLLOTOXINE-BETA-D-GLUCOSIDE AND PROCESS FOR PREPARING A PHARMACEUTICAL PREPARATION FOR PATHOLOGICAL PROCESSES COVERED ATTENDED AND MEAT-PREPARED PREPARATELY. METHOD.

Country Status (9)

Country Link
AT (2) AT319971B (en)
BR (1) BR6906655D0 (en)
CA (1) CA956939A (en)
CH (2) CH514578A (en)
CS (2) CS153032B2 (en)
DK (2) DK123715B (en)
FI (1) FI48924C (en)
NL (1) NL166028C (en)
SU (2) SU447886A3 (en)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3374317D1 (en) * 1982-11-26 1987-12-10 Nippon Kayaku Kk Process for producing 4'-demethyl-epipodophyllotoxin-beta-d-ethylidene-glucoside and acyl-derivative thereof
JPS61189230A (en) * 1985-02-19 1986-08-22 Nippon Kayaku Co Ltd Etoposide preparation
IL77334A (en) * 1985-12-16 1991-04-15 Univ Bar Ilan Synthesis of 9-epipodophyllotoxin glucoside derivatives and some novel intermediates therefor
US4904768A (en) * 1987-08-04 1990-02-27 Bristol-Myers Company Epipodophyllotoxin glucoside 4'-phosphate derivatives
US4935504A (en) * 1987-12-18 1990-06-19 Bristol-Myers Company Epipodophyllotoxin glucoside 4'-acyl derivatives
US5036055A (en) * 1989-06-07 1991-07-30 Bristol-Myers Company Acylated derivatives of etoposide
US5066645A (en) * 1989-09-01 1991-11-19 Bristol-Myers Company Epipodophyllotoxin altroside derivatives
US5463040A (en) * 1994-06-28 1995-10-31 Teva Pharmaceutical Industries, Ltd. Method of preparing etoposide
US8173621B2 (en) 2008-06-11 2012-05-08 Gilead Pharmasset Llc Nucleoside cyclicphosphates
CL2009002207A1 (en) 2008-12-23 2011-02-18 Gilead Pharmasset Llc Compounds derived from 3-hydroxy-5- (9h-purin-9-yl) tetrahydrofuran-2-yl, an inhibitor of the replication of arn-dependent viral arn; pharmaceutical composition; use for the treatment of hepatitis c.
WO2010075517A2 (en) 2008-12-23 2010-07-01 Pharmasset, Inc. Nucleoside analogs
SG172363A1 (en) 2008-12-23 2011-07-28 Pharmasset Inc Synthesis of purine nucleosides
AP3515A (en) 2010-03-31 2016-01-11 Gilead Pharmasset Llc Nucleoside phosphoramidates
IL261721B (en) 2016-03-15 2022-07-01 Oryzon Genomics Sa Combinations of lsd1 inhibitors for use in the treatment of solid tumors

Also Published As

Publication number Publication date
CA956939A (en) 1974-10-29
SU406346A3 (en) 1973-11-05
AT303270B (en) 1972-11-27
AT319971B (en) 1975-01-27
DK123715B (en) 1972-07-24
NL6901619A (en) 1969-08-29
FI48924C (en) 1975-02-10
SU447886A3 (en) 1974-10-25
CS153032B2 (en) 1974-02-22
DK128563B (en) 1974-05-27
CH518927A (en) 1972-02-15
BR6906655D0 (en) 1973-01-09
FI48924B (en) 1974-10-31
NL166028C (en) 1981-06-15
CS153033B2 (en) 1974-02-22
CH514578A (en) 1971-10-31

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