NL165652B - Werkwijze ter bereiding van een preparaat met anti- trombosewerking en/of diagnosticum voor trombine in bloed op basis van l-argininederivaten, het gevormde preparaat, het gevormde diagnosticum en werkwijze ter bereiding van l-argininederivaten. - Google Patents
Werkwijze ter bereiding van een preparaat met anti- trombosewerking en/of diagnosticum voor trombine in bloed op basis van l-argininederivaten, het gevormde preparaat, het gevormde diagnosticum en werkwijze ter bereiding van l-argininederivaten.Info
- Publication number
- NL165652B NL165652B NL7410647.A NL7410647A NL165652B NL 165652 B NL165652 B NL 165652B NL 7410647 A NL7410647 A NL 7410647A NL 165652 B NL165652 B NL 165652B
- Authority
- NL
- Netherlands
- Prior art keywords
- preparation
- prepared
- diagnostic
- thrombine
- blood
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D265/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom and one oxygen atom as the only ring hetero atoms
- C07D265/28—1,4-Oxazines; Hydrogenated 1,4-oxazines
- C07D265/30—1,4-Oxazines; Hydrogenated 1,4-oxazines not condensed with other rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/04—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D207/10—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D207/16—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/08—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
- C07D211/10—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with radicals containing only carbon and hydrogen atoms attached to ring carbon atoms
- C07D211/16—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with radicals containing only carbon and hydrogen atoms attached to ring carbon atoms with acylated ring nitrogen atom
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/08—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
- C07D211/18—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D211/30—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by doubly bound oxygen or sulfur atoms or by two oxygen or sulfur atoms singly bound to the same carbon atom
- C07D211/32—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by doubly bound oxygen or sulfur atoms or by two oxygen or sulfur atoms singly bound to the same carbon atom by oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D211/60—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D211/62—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals attached in position 4
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/04—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, directly attached to the ring carbon atoms
- C07D215/08—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, directly attached to the ring carbon atoms with acylated ring nitrogen atom
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/16—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms
- C07D295/18—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms by radicals derived from carboxylic acids, or sulfur or nitrogen analogues thereof
- C07D295/182—Radicals derived from carboxylic acids
- C07D295/185—Radicals derived from carboxylic acids from aliphatic carboxylic acids
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
- C07D307/04—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
- C07D307/10—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D307/12—Radicals substituted by oxygen atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Peptides Or Proteins (AREA)
- Hydrogenated Pyridines (AREA)
Applications Claiming Priority (7)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP9069973A JPS5521742B2 (nl) | 1973-08-13 | 1973-08-13 | |
JP11603573A JPS5521743B2 (nl) | 1973-10-16 | 1973-10-16 | |
JP11729273A JPS5521744B2 (nl) | 1973-10-18 | 1973-10-18 | |
JP13750173A JPS5521745B2 (nl) | 1973-12-10 | 1973-12-10 | |
JP3114174A JPS5542073B2 (nl) | 1974-03-19 | 1974-03-19 | |
JP3326074A JPS5521746B2 (nl) | 1974-03-25 | 1974-03-25 | |
JP6157374A JPS5542074B2 (nl) | 1974-05-31 | 1974-05-31 |
Publications (3)
Publication Number | Publication Date |
---|---|
NL7410647A NL7410647A (nl) | 1975-02-17 |
NL165652B true NL165652B (nl) | 1980-12-15 |
NL165652C NL165652C (nl) | 1981-05-15 |
Family
ID=27564271
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
NL7410647.A NL165652C (nl) | 1973-08-13 | 1974-08-08 | Werkwijze ter bereiding van een preparaat met anti- trombosewerking en/of diagnosticum voor trombine in bloed op basis van l-argininederivaten, het gevormde preparaat, het gevormde diagnosticum en werkwijze ter bereiding van l-argininederivaten. |
Country Status (9)
Country | Link |
---|---|
US (1) | US4670420A (nl) |
CA (1) | CA1029026A (nl) |
CH (4) | CH612929A5 (nl) |
DE (1) | DE2438851C2 (nl) |
DK (1) | DK140431B (nl) |
FR (1) | FR2240720B1 (nl) |
GB (1) | GB1475346A (nl) |
NL (1) | NL165652C (nl) |
NO (1) | NO140344C (nl) |
Families Citing this family (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
NL7512637A (nl) * | 1974-11-08 | 1976-05-11 | Mitsubishi Chem Ind | Werkwijze ter bereiding van een geneesmiddel, het aldus gevormde geneesmiddel en werkwijze voor de bereiding van actieve component. |
CA1102316A (en) * | 1975-12-09 | 1981-06-02 | Shosuke Okamoto | N su2 xx-arylsulfonyl-l-argininamides and the pharmaceutically acceptable salts thereof |
FR2378004B2 (fr) * | 1975-12-09 | 1985-09-13 | Mitsubishi Chem Ind | Derives de l'argininamide, leur preparation et leurs utilisations therapeutiques |
EP0190852A3 (en) * | 1985-01-31 | 1988-11-02 | Ajinomoto Co., Inc. | Dipeptide derivatives and antihypertensive drugs containing them |
JP4010951B2 (ja) * | 2001-05-15 | 2007-11-21 | 大正製薬株式会社 | アルギニン誘導体 |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
SE420919B (sv) * | 1973-08-13 | 1981-11-09 | Mitsubishi Chem Ind | Forfarande for framstellning av n?722-dansyl-l-argininderivat och farmaceutiskt godtagbara syradditionssalter derav |
US4069329A (en) * | 1974-11-08 | 1978-01-17 | Mitsubishi Chemical Industries Limited | N2 -Naphthalenesulfonyl-L-arginine derivatives, and the pharmaceutically acceptable acid addition salts thereof |
US4072744A (en) * | 1974-11-08 | 1978-02-07 | Mitsubishi Chemical Industries Limited | N2 -naphthalenesulfonyl-L-argininamides and the pharmaceutically acceptable salts thereof |
US4069317A (en) * | 1974-11-08 | 1978-01-17 | Mitsubishi Chemical Industries Ltd. | N2 -Arylsulfonyl-L-argininamides and the pharmaceutically acceptable salts thereof |
US4072743A (en) * | 1974-11-08 | 1978-02-07 | Mitsubishi Chemical Industries Limited | N2 -arylsulfonyl-L-argininamides and the pharmaceutically acceptable salts thereof |
-
1974
- 1974-08-08 NL NL7410647.A patent/NL165652C/nl not_active IP Right Cessation
- 1974-08-09 CA CA206,760A patent/CA1029026A/en not_active Expired
- 1974-08-12 NO NO742886A patent/NO140344C/no unknown
- 1974-08-12 FR FR7427891A patent/FR2240720B1/fr not_active Expired
- 1974-08-12 GB GB3550174A patent/GB1475346A/en not_active Expired
- 1974-08-12 DK DK429474AA patent/DK140431B/da not_active IP Right Cessation
- 1974-08-13 DE DE2438851A patent/DE2438851C2/de not_active Expired
- 1974-08-13 CH CH1588877A patent/CH612929A5/xx not_active IP Right Cessation
- 1974-08-13 CH CH1588677A patent/CH613946A5/xx not_active IP Right Cessation
- 1974-08-13 CH CH1588777A patent/CH612928A5/xx not_active IP Right Cessation
- 1974-08-13 CH CH1104074A patent/CH613945A5/xx not_active IP Right Cessation
-
1980
- 1980-02-04 US US06/118,096 patent/US4670420A/en not_active Expired - Lifetime
Also Published As
Publication number | Publication date |
---|---|
DK140431B (da) | 1979-08-27 |
DK140431C (nl) | 1980-01-28 |
CH612929A5 (nl) | 1979-08-31 |
CH613945A5 (nl) | 1979-10-31 |
CH613946A5 (nl) | 1979-10-31 |
NL165652C (nl) | 1981-05-15 |
FR2240720B1 (nl) | 1978-07-21 |
GB1475346A (en) | 1977-06-01 |
CA1029026A (en) | 1978-04-04 |
DE2438851A1 (de) | 1975-02-27 |
NO140344C (no) | 1979-08-15 |
NO742886L (nl) | 1975-03-10 |
CH612928A5 (nl) | 1979-08-31 |
DE2438851C2 (de) | 1987-03-19 |
US4670420A (en) | 1987-06-02 |
DK429474A (nl) | 1975-04-21 |
NO140344B (no) | 1979-05-07 |
FR2240720A1 (nl) | 1975-03-14 |
NL7410647A (nl) | 1975-02-17 |
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Legal Events
Date | Code | Title | Description |
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BK | Erratum |
Free format text: IE NR,12V,80:UITVINDERS MOET ZIJN RYOJI KIKUMOTO TE TOKYO,YOSHIKUNI TAMAO TE YOKOHAMA ENZ. |
|
V1 | Lapsed because of non-payment of the annual fee |