NL151088B - PROCEDURE FOR PREPARING 5-PREGNEEN3BETA, 17ALFA, 21-TRIOL-20-ON-21-ACYLATES FROM MATCHING 5-PREGNES-3BETA, 17ALFA-DIOL-20-ONES BY BROMOMERING THESE FIRST TO 5,6,21-TRIBROOMER COMPOUNDS , THEN REGENERATING THE 5,6 DOUBLE BONDING WITH AN ALKALINE METAL IODIDE AND EXCHANGE THE 21-HALOGEN ATOM FOR AN ACYLOXY GROUP. - Google Patents

PROCEDURE FOR PREPARING 5-PREGNEEN3BETA, 17ALFA, 21-TRIOL-20-ON-21-ACYLATES FROM MATCHING 5-PREGNES-3BETA, 17ALFA-DIOL-20-ONES BY BROMOMERING THESE FIRST TO 5,6,21-TRIBROOMER COMPOUNDS , THEN REGENERATING THE 5,6 DOUBLE BONDING WITH AN ALKALINE METAL IODIDE AND EXCHANGE THE 21-HALOGEN ATOM FOR AN ACYLOXY GROUP.

Info

Publication number
NL151088B
NL151088B NL6406306A NL6406306A NL151088B NL 151088 B NL151088 B NL 151088B NL 6406306 A NL6406306 A NL 6406306A NL 6406306 A NL6406306 A NL 6406306A NL 151088 B NL151088 B NL 151088B
Authority
NL
Netherlands
Prior art keywords
17alfa
tribroomer
pregnes
bromomering
3beta
Prior art date
Application number
NL6406306A
Other languages
Dutch (nl)
Other versions
NL6406306A (en
Original Assignee
Steromex S A
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US286959A external-priority patent/US3187025A/en
Priority claimed from US347399A external-priority patent/US3231568A/en
Application filed by Steromex S A filed Critical Steromex S A
Publication of NL6406306A publication Critical patent/NL6406306A/xx
Publication of NL151088B publication Critical patent/NL151088B/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J5/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J75/00—Processes for the preparation of steroids in general

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Steroid Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
NL6406306A 1963-06-11 1964-06-04 PROCEDURE FOR PREPARING 5-PREGNEEN3BETA, 17ALFA, 21-TRIOL-20-ON-21-ACYLATES FROM MATCHING 5-PREGNES-3BETA, 17ALFA-DIOL-20-ONES BY BROMOMERING THESE FIRST TO 5,6,21-TRIBROOMER COMPOUNDS , THEN REGENERATING THE 5,6 DOUBLE BONDING WITH AN ALKALINE METAL IODIDE AND EXCHANGE THE 21-HALOGEN ATOM FOR AN ACYLOXY GROUP. NL151088B (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US286959A US3187025A (en) 1963-06-11 1963-06-11 Process for preparing compound s
US347399A US3231568A (en) 1964-02-26 1964-02-26 Processes and intermediates for preparing 16alpha-methyl corticoids

Publications (2)

Publication Number Publication Date
NL6406306A NL6406306A (en) 1964-12-14
NL151088B true NL151088B (en) 1976-10-15

Family

ID=26964160

Family Applications (2)

Application Number Title Priority Date Filing Date
NL6406306A NL151088B (en) 1963-06-11 1964-06-04 PROCEDURE FOR PREPARING 5-PREGNEEN3BETA, 17ALFA, 21-TRIOL-20-ON-21-ACYLATES FROM MATCHING 5-PREGNES-3BETA, 17ALFA-DIOL-20-ONES BY BROMOMERING THESE FIRST TO 5,6,21-TRIBROOMER COMPOUNDS , THEN REGENERATING THE 5,6 DOUBLE BONDING WITH AN ALKALINE METAL IODIDE AND EXCHANGE THE 21-HALOGEN ATOM FOR AN ACYLOXY GROUP.
NL6406303A NL6406303A (en) 1963-06-11 1964-06-04

Family Applications After (1)

Application Number Title Priority Date Filing Date
NL6406303A NL6406303A (en) 1963-06-11 1964-06-04

Country Status (6)

Country Link
BE (1) BE649163A (en)
CH (1) CH433286A (en)
DE (1) DE1235907B (en)
GB (2) GB1060354A (en)
IT (2) IT1048877B (en)
NL (2) NL151088B (en)

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1060392B (en) * 1958-02-20 1959-07-02 Merck Ag E Process for the production of Reichsteins substance S
DE1060860B (en) * 1958-03-29 1959-07-09 Merck Ag E Process for the production of Reichsteins substance S

Also Published As

Publication number Publication date
GB1059643A (en) 1967-02-22
NL6406306A (en) 1964-12-14
CH433286A (en) 1967-04-15
BE649163A (en) 1964-12-11
IT1048876B (en) 1980-12-20
DE1235907B (en) 1967-03-09
NL6406303A (en) 1964-12-14
IT1048877B (en) 1980-12-20
GB1060354A (en) 1967-03-01

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