NL140730B - Werkwijze voor de bereiding van gesubstitueerde chromoncabonzuur-2-derivaten met remmende werking op anafylactische reacties. - Google Patents

Werkwijze voor de bereiding van gesubstitueerde chromoncabonzuur-2-derivaten met remmende werking op anafylactische reacties.

Info

Publication number
NL140730B
NL140730B NL646411222A NL6411222A NL140730B NL 140730 B NL140730 B NL 140730B NL 646411222 A NL646411222 A NL 646411222A NL 6411222 A NL6411222 A NL 6411222A NL 140730 B NL140730 B NL 140730B
Authority
NL
Netherlands
Prior art keywords
chromoncabonic
derivatives
substituted
preparation
acid
Prior art date
Application number
NL646411222A
Other languages
English (en)
Other versions
NL6411222A (nl
Original Assignee
Fisons Pharmaceuticals Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB38068/63A external-priority patent/GB1093673A/en
Application filed by Fisons Pharmaceuticals Ltd filed Critical Fisons Pharmaceuticals Ltd
Publication of NL6411222A publication Critical patent/NL6411222A/xx
Publication of NL140730B publication Critical patent/NL140730B/nl

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D407/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00
    • C07D407/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings
    • C07D407/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/61—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
    • C07C45/63—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by introduction of halogen; by substitution of halogen atoms by other halogen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/61—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
    • C07C45/67—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton
    • C07C45/673—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by change of size of the carbon skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/61—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
    • C07C45/67—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton
    • C07C45/68—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms
    • C07C45/70—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms by reaction with functional groups containing oxygen only in singly bound form
    • C07C45/71—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms by reaction with functional groups containing oxygen only in singly bound form being hydroxy groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C49/00—Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
    • C07C49/76—Ketones containing a keto group bound to a six-membered aromatic ring
    • C07C49/82—Ketones containing a keto group bound to a six-membered aromatic ring containing hydroxy groups
    • C07C49/825—Ketones containing a keto group bound to a six-membered aromatic ring containing hydroxy groups all hydroxy groups bound to the ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C49/00—Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
    • C07C49/76—Ketones containing a keto group bound to a six-membered aromatic ring
    • C07C49/84—Ketones containing a keto group bound to a six-membered aromatic ring containing ether groups, groups, groups, or groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
    • C07D311/22—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4
    • C07D311/24—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4 with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D493/00—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
    • C07D493/02—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains two hetero rings
    • C07D493/04—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
NL646411222A 1963-09-27 1964-09-25 Werkwijze voor de bereiding van gesubstitueerde chromoncabonzuur-2-derivaten met remmende werking op anafylactische reacties. NL140730B (nl)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB38068/63A GB1093673A (en) 1963-09-27 1963-09-27 Novel chromone carboxylic acids
GB2519264 1964-06-18
US61021267A 1967-01-16 1967-01-16

Publications (2)

Publication Number Publication Date
NL6411222A NL6411222A (nl) 1965-03-29
NL140730B true NL140730B (nl) 1974-01-15

Family

ID=27258418

Family Applications (1)

Application Number Title Priority Date Filing Date
NL646411222A NL140730B (nl) 1963-09-27 1964-09-25 Werkwijze voor de bereiding van gesubstitueerde chromoncabonzuur-2-derivaten met remmende werking op anafylactische reacties.

Country Status (2)

Country Link
US (1) US3427324A (nl)
NL (1) NL140730B (nl)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1147976A (en) * 1965-12-21 1969-04-10 Fisons Pharmaceuticals Ltd Chromone derivatives
US3864493A (en) * 1967-08-17 1975-02-04 Fisons Ltd Felixstowe Compositions and methods for the prevention of asthmatic symptoms
GB1230087A (nl) * 1967-08-17 1971-04-28
GB1362782A (en) * 1970-08-26 1974-08-07 Fisons Ltd Tetrazole derivatives
GB1340512A (en) * 1970-01-21 1973-12-12 Fisons Ltd Production of esters of chromone-2-carboxylic acids
GB1296469A (nl) * 1970-02-05 1972-11-15
US3720690A (en) * 1970-04-10 1973-03-13 Fisons Pharmaceuticals Ltd Pharmaceutically active bis-carboxychromone compounds
US4055654A (en) * 1970-08-25 1977-10-25 Fisons Limited 6,8-Di-t-butyl-4-oxo-4H-1-benzopyran-2-carboxylic acid and derivative for the prevention of asthmatic symptoms
US3952104A (en) * 1970-08-25 1976-04-20 Fisons Limited Benzopyran-2-carboxylic acids in the prevention of asthmatic symptoms
US4064256A (en) * 1970-08-26 1977-12-20 Fisons Limited Benzopyranyltetrazoles as antiasthma agents
BE789822A (fr) * 1971-10-08 1973-04-06 Allen & Hanburys Ltd Nouveaux composes heterocycliques
GB1428186A (en) * 1972-06-21 1976-03-17 Fujisawa Pharmaceutical Co Chromone derivatives
GB1488707A (en) * 1974-07-10 1977-10-12 Fisons Ltd 5-(2-hydroxy-propoxy)-4-oxo-8-propyl-4h-1-benzopyran-2-carboxylic acid and derivatives thereof
US4035368A (en) * 1975-04-02 1977-07-12 Riker Laboratories, Inc. Substituted 3-(1H-tetrazol-5-yl)-quinoline compounds
US4211788A (en) * 1977-05-21 1980-07-08 Fisons Limited Compounds
FR2453170A1 (fr) * 1979-04-06 1980-10-31 Clin Midy Acides 5-(2-hydroxy-3-thiopropoxy)chromone-2-carboxyliques et leurs applications comme medicaments presentant notamment des proprietes antianaphylactiques et antiallergiques
EP0104018A3 (en) * 1982-09-21 1985-06-26 FISONS plc Benzopyran, benzothiapyran and quinoline compounds and pharmaceutical compositions containing them
AU2007304881B2 (en) 2006-10-04 2013-03-07 Bionomics Limited Novel chromenone potassium channel blockers and uses thereof

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR980302A (fr) * 1943-01-21 1951-05-10 Chimiotherapie Lab Franc Procédé de préparation de la méthyl-3-chromone

Also Published As

Publication number Publication date
US3427324A (en) 1969-02-11
NL6411222A (nl) 1965-03-29

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