NL140243B - Werkwijze ter bereiding van 7-((gesubstitueerde) fenylacetylamino)-3-(1-pyridylmethyl)-3-cefem-4-carbonzuurderivaten. - Google Patents

Werkwijze ter bereiding van 7-((gesubstitueerde) fenylacetylamino)-3-(1-pyridylmethyl)-3-cefem-4-carbonzuurderivaten.

Info

Publication number
NL140243B
NL140243B NL646403229A NL6403229A NL140243B NL 140243 B NL140243 B NL 140243B NL 646403229 A NL646403229 A NL 646403229A NL 6403229 A NL6403229 A NL 6403229A NL 140243 B NL140243 B NL 140243B
Authority
NL
Netherlands
Prior art keywords
substituated
cefem
phenylacetylamino
pyridylmethyl
preparing
Prior art date
Application number
NL646403229A
Other languages
English (en)
Dutch (nl)
Other versions
NL6403229A (xx
Original Assignee
Glaxo Lab Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Glaxo Lab Ltd filed Critical Glaxo Lab Ltd
Publication of NL6403229A publication Critical patent/NL6403229A/xx
Publication of NL140243B publication Critical patent/NL140243B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14—Compounds having a nitrogen atom directly attached in position 7
    • C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
    • C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
    • C07D501/24—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with hydrocarbon radicals, substituted by hetero atoms or hetero rings, attached in position 3
    • C07D501/38—Methylene radicals, substituted by nitrogen atoms; Lactams thereof with the 2-carboxyl group; Methylene radicals substituted by nitrogen-containing hetero rings attached by the ring nitrogen atom; Quaternary compounds thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/54—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame
    • A61K31/542—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/545—Compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins, cefaclor, or cephalexine
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14—Compounds having a nitrogen atom directly attached in position 7
    • C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
    • C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
    • C07D501/24—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with hydrocarbon radicals, substituted by hetero atoms or hetero rings, attached in position 3
    • C07D501/38—Methylene radicals, substituted by nitrogen atoms; Lactams thereof with the 2-carboxyl group; Methylene radicals substituted by nitrogen-containing hetero rings attached by the ring nitrogen atom; Quaternary compounds thereof
    • C07D501/42—Methylene radicals, substituted by nitrogen atoms; Lactams thereof with the 2-carboxyl group; Methylene radicals substituted by nitrogen-containing hetero rings attached by the ring nitrogen atom; Quaternary compounds thereof with the 7-amino radical acylated by an araliphatic carboxylic acid

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Cephalosporin Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
NL646403229A 1963-05-28 1964-03-25 Werkwijze ter bereiding van 7-((gesubstitueerde) fenylacetylamino)-3-(1-pyridylmethyl)-3-cefem-4-carbonzuurderivaten. NL140243B (nl)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB2128463A GB1082962A (en) 1963-05-28 1963-05-28 Derivatives of 7-aminocephalosporanic acid

Publications (2)

Publication Number Publication Date
NL6403229A NL6403229A (xx) 1964-11-30
NL140243B true NL140243B (nl) 1973-11-15

Family

ID=10160300

Family Applications (1)

Application Number Title Priority Date Filing Date
NL646403229A NL140243B (nl) 1963-05-28 1964-03-25 Werkwijze ter bereiding van 7-((gesubstitueerde) fenylacetylamino)-3-(1-pyridylmethyl)-3-cefem-4-carbonzuurderivaten.

Country Status (7)

Country Link
AT (1) AT261110B (xx)
BE (1) BE645868A (xx)
CH (1) CH515274A (xx)
ES (1) ES298060A1 (xx)
FR (1) FR4201M (xx)
GB (1) GB1082962A (xx)
NL (1) NL140243B (xx)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1476981A (en) * 1974-06-05 1977-06-16 Bristol Myers Co Substituted penicillanic acids
DE3118732A1 (de) * 1981-05-12 1982-12-02 Hoechst Ag, 6000 Frankfurt Cephalosporinderivate und verfahren zu ihrer herstellung

Also Published As

Publication number Publication date
DE1445831A1 (de) 1969-05-22
DE1445831B2 (de) 1976-04-08
FR4201M (xx) 1966-06-06
GB1082962A (en) 1967-09-13
ES298060A1 (es) 1964-09-01
CH515274A (de) 1971-11-15
NL6403229A (xx) 1964-11-30
BE645868A (xx) 1964-09-28
AT261110B (de) 1968-04-10

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