NL1030418C2 - Azabenzoxazolen voor de behandeling van CZS-stoornissen. - Google Patents
Azabenzoxazolen voor de behandeling van CZS-stoornissen. Download PDFInfo
- Publication number
- NL1030418C2 NL1030418C2 NL1030418A NL1030418A NL1030418C2 NL 1030418 C2 NL1030418 C2 NL 1030418C2 NL 1030418 A NL1030418 A NL 1030418A NL 1030418 A NL1030418 A NL 1030418A NL 1030418 C2 NL1030418 C2 NL 1030418C2
- Authority
- NL
- Netherlands
- Prior art keywords
- disease
- alkyl
- aryl
- disorder
- pharmaceutically acceptable
- Prior art date
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- 208000015114 central nervous system disease Diseases 0.000 title description 2
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- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 44
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- -1 -CF 3 Chemical group 0.000 description 36
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- 150000003839 salts Chemical class 0.000 description 36
- 239000000203 mixture Substances 0.000 description 35
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- C07D519/00—Heterocyclic compounds containing more than one system of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring system not provided for in groups C07D453/00 or C07D455/00
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- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
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- C07D498/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
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Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US60896404P | 2004-11-15 | 2004-11-15 | |
| US60896404 | 2004-11-15 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| NL1030418A1 NL1030418A1 (nl) | 2006-05-16 |
| NL1030418C2 true NL1030418C2 (nl) | 2006-11-23 |
Family
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NL1030418A NL1030418C2 (nl) | 2004-11-15 | 2005-11-14 | Azabenzoxazolen voor de behandeling van CZS-stoornissen. |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US20060173179A1 (enExample) |
| EP (1) | EP1814888A1 (enExample) |
| JP (1) | JP2008519818A (enExample) |
| AR (1) | AR051955A1 (enExample) |
| CA (1) | CA2587461A1 (enExample) |
| GT (1) | GT200500332A (enExample) |
| NL (1) | NL1030418C2 (enExample) |
| PE (1) | PE20061133A1 (enExample) |
| TW (1) | TW200631956A (enExample) |
| UY (1) | UY29212A1 (enExample) |
| WO (1) | WO2006051394A1 (enExample) |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102775396B (zh) | 2005-11-08 | 2014-10-08 | 沃泰克斯药物股份有限公司 | Atp-结合弹夹转运蛋白的杂环调控剂 |
| WO2007083954A1 (en) * | 2006-01-23 | 2007-07-26 | Lg Electronics Inc. | Method for scheduling device management and terminal thereof |
| JP5497633B2 (ja) | 2007-05-09 | 2014-05-21 | バーテックス ファーマシューティカルズ インコーポレイテッド | Cftrのモジュレーター |
| NZ614151A (en) | 2007-12-07 | 2015-04-24 | Vertex Pharma | Solid forms of 3-(6-(1-(2,2-difluorobenzo[d][1,3]dioxol-5-yl) cyclopropanecarboxamido)-3-methylpyridin-2-yl)benzoic acid |
| EP2231606B1 (en) | 2007-12-07 | 2013-02-13 | Vertex Pharmaceuticals Incorporated | Processes for producing cycloalkylcarboxiamido-pyridine benzoic acids |
| ES2647531T3 (es) | 2008-02-28 | 2017-12-22 | Vertex Pharmaceuticals Incorporated | Derivados de heteroarilo como moduladores de CFTR |
| TWI558398B (zh) * | 2009-09-22 | 2016-11-21 | 諾華公司 | 菸鹼乙醯膽鹼受體α7活化劑之用途 |
| ES3017582T3 (en) | 2010-04-07 | 2025-05-13 | Vertex Pharma | Pharmaceutical compositions of 3-(6-(1-(2,2-difluorobenzo[d][1,3]dioxol-5-yl) cyclopropanecarboxamido)-3-methylpyriodin-2-yl)benzoic acid and administration thereof |
| BR112013018726A2 (pt) * | 2011-01-27 | 2016-10-25 | Novartis Ag | uso de ativadores de alfa 7 do receptor nicotínico de acetilcolina |
| JP6440625B2 (ja) | 2012-11-14 | 2018-12-19 | ザ・ジョンズ・ホプキンス・ユニバーシティー | 精神分裂病を処置するための方法および組成物 |
| CN105848657B (zh) | 2013-11-12 | 2020-05-22 | 沃泰克斯药物股份有限公司 | 制备用于治疗cftr介导的疾病的药物组合物的方法 |
| SI3221692T1 (sl) | 2014-11-18 | 2021-11-30 | Vertex Pharmaceuticals Inc. | Postopek za izvajanje testov visoke prepustnosti z visoko zmogljivostno tekočinsko kromatografijo |
| CN107188900B (zh) * | 2017-05-27 | 2019-09-06 | 北京师范大学 | α7烟碱型乙酰胆碱受体的配体化合物及其应用 |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
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| US20020086871A1 (en) * | 2000-12-29 | 2002-07-04 | O'neill Brian Thomas | Pharmaceutical composition for the treatment of CNS and other disorders |
| FR2832714B1 (fr) * | 2001-11-23 | 2004-07-16 | Sanofi Synthelabo | Derives de 4-(oxazolopyridin-2-yl)-1,4-diazabicyclo[3.2.2] nonane, leur preparation et leur application en therapeutique |
| BRPI0418092A (pt) * | 2003-12-23 | 2007-04-17 | Pfizer Prod Inc | combinação terapêutica para melhora cognitiva e transtornos psicóticos |
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2005
- 2005-11-03 WO PCT/IB2005/003364 patent/WO2006051394A1/en not_active Ceased
- 2005-11-03 CA CA002587461A patent/CA2587461A1/en not_active Abandoned
- 2005-11-03 JP JP2007540742A patent/JP2008519818A/ja not_active Abandoned
- 2005-11-03 EP EP05805178A patent/EP1814888A1/en not_active Withdrawn
- 2005-11-11 AR ARP050104739A patent/AR051955A1/es unknown
- 2005-11-11 PE PE2005001321A patent/PE20061133A1/es not_active Application Discontinuation
- 2005-11-14 TW TW094139977A patent/TW200631956A/zh unknown
- 2005-11-14 UY UY29212A patent/UY29212A1/es not_active Application Discontinuation
- 2005-11-14 US US11/273,657 patent/US20060173179A1/en not_active Abandoned
- 2005-11-14 NL NL1030418A patent/NL1030418C2/nl not_active IP Right Cessation
- 2005-11-15 GT GT200500332A patent/GT200500332A/es unknown
Also Published As
| Publication number | Publication date |
|---|---|
| WO2006051394A1 (en) | 2006-05-18 |
| UY29212A1 (es) | 2006-06-30 |
| CA2587461A1 (en) | 2006-05-18 |
| EP1814888A1 (en) | 2007-08-08 |
| US20060173179A1 (en) | 2006-08-03 |
| PE20061133A1 (es) | 2006-10-26 |
| AR051955A1 (es) | 2007-02-21 |
| TW200631956A (en) | 2006-09-16 |
| JP2008519818A (ja) | 2008-06-12 |
| NL1030418A1 (nl) | 2006-05-16 |
| GT200500332A (es) | 2006-06-13 |
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