MY199070A - Substituted indazoles useful for treatment and prevention of allergic and/or inflammatory diseaes in animals - Google Patents

Substituted indazoles useful for treatment and prevention of allergic and/or inflammatory diseaes in animals

Info

Publication number
MY199070A
MY199070A MYPI2018002212A MYPI2018002212A MY199070A MY 199070 A MY199070 A MY 199070A MY PI2018002212 A MYPI2018002212 A MY PI2018002212A MY PI2018002212 A MYPI2018002212 A MY PI2018002212A MY 199070 A MY199070 A MY 199070A
Authority
MY
Malaysia
Prior art keywords
animals
treatment
inflammatory
allergic
diseaes
Prior art date
Application number
MYPI2018002212A
Inventor
Gerald Beddies
Adrian Foster
Ulrich Bothe
Nicole Schmidt
Ulf Bomer
Reinhard Nubbemeyer
Maria De Lourdes Mottier
Original Assignee
Bayer Pharma AG
Bayer Animal Health Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer Pharma AG, Bayer Animal Health Gmbh filed Critical Bayer Pharma AG
Publication of MY199070A publication Critical patent/MY199070A/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4427Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
    • A61K31/4439Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4412Non condensed pyridines; Hydrogenated derivatives thereof having oxo groups directly attached to the heterocyclic ring
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/04Drugs for disorders of the respiratory system for throat disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/06Antiasthmatics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00Drugs for genital or sexual disorders; Contraceptives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00Drugs for genital or sexual disorders; Contraceptives
    • A61P15/14Drugs for genital or sexual disorders; Contraceptives for lactation disorders, e.g. galactorrhoea
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/02Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/08Antiallergic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D405/00Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/14Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pulmonology (AREA)
  • Immunology (AREA)
  • Rheumatology (AREA)
  • Epidemiology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Pain & Pain Management (AREA)
  • Endocrinology (AREA)
  • Reproductive Health (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Dermatology (AREA)
  • Pregnancy & Childbirth (AREA)
  • Gynecology & Obstetrics (AREA)
  • Otolaryngology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

The present application relates to the use of substituted indazoles for treatment and/or prophylaxis of allergic and/or inflammatory diseases in animals, especially for treatment and/or prophylaxis of atopic dermatitis, Flea Allergy Dermatitis, inflammatory bowel disease, osteoarthritis and inflammatory pain, non-infectious recurrent airway disease, insect hypersensitivity, asthma, respiratory disease, mastitis and endometritis in animals. (Fig. 7)
MYPI2018002212A 2016-06-01 2017-05-29 Substituted indazoles useful for treatment and prevention of allergic and/or inflammatory diseaes in animals MY199070A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP16172544 2016-06-01
PCT/EP2017/062876 WO2017207481A1 (en) 2016-06-01 2017-05-29 Substituted indazoles ueful for treatment and prevention of allergic and/or inflammatory diseases in animals

Publications (1)

Publication Number Publication Date
MY199070A true MY199070A (en) 2023-10-12

Family

ID=56097024

Family Applications (1)

Application Number Title Priority Date Filing Date
MYPI2018002212A MY199070A (en) 2016-06-01 2017-05-29 Substituted indazoles useful for treatment and prevention of allergic and/or inflammatory diseaes in animals

Country Status (25)

Country Link
US (2) US20200216413A1 (en)
EP (1) EP3464266B1 (en)
JP (1) JP7004677B2 (en)
KR (1) KR102547834B1 (en)
CN (3) CN109219603B (en)
AU (1) AU2017272505B9 (en)
BR (1) BR112018074927A2 (en)
CA (1) CA3025847A1 (en)
CL (1) CL2018003432A1 (en)
CO (1) CO2018013029A2 (en)
DK (1) DK3464266T3 (en)
DO (1) DOP2018000262A (en)
ES (1) ES2898771T3 (en)
IL (1) IL263132B (en)
MX (1) MX394560B (en)
MY (1) MY199070A (en)
PH (1) PH12018502530A1 (en)
PL (1) PL3464266T3 (en)
PT (1) PT3464266T (en)
RU (1) RU2743170C2 (en)
SG (1) SG11201809470RA (en)
SI (1) SI3464266T1 (en)
TW (1) TWI781935B (en)
UA (1) UA124237C2 (en)
WO (1) WO2017207481A1 (en)

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Also Published As

Publication number Publication date
CN109219603A (en) 2019-01-15
RU2743170C2 (en) 2021-02-15
MX394560B (en) 2025-03-24
US20200216413A1 (en) 2020-07-09
UA124237C2 (en) 2021-08-11
DOP2018000262A (en) 2019-02-28
NZ747414A (en) 2025-06-27
CA3025847A1 (en) 2017-12-07
US12459916B2 (en) 2025-11-04
ES2898771T3 (en) 2022-03-08
SI3464266T1 (en) 2021-12-31
JP7004677B2 (en) 2022-01-21
TWI781935B (en) 2022-11-01
CL2018003432A1 (en) 2019-03-22
SG11201809470RA (en) 2018-11-29
CO2018013029A2 (en) 2018-12-28
KR20190015252A (en) 2019-02-13
CN120531733A (en) 2025-08-26
IL263132A (en) 2018-12-31
JP2019520348A (en) 2019-07-18
MX2018014899A (en) 2019-04-24
KR102547834B1 (en) 2023-06-26
BR112018074927A2 (en) 2019-03-12
CN109219603B (en) 2025-06-27
WO2017207481A1 (en) 2017-12-07
PH12018502530A1 (en) 2019-10-21
PL3464266T3 (en) 2022-01-24
EP3464266B1 (en) 2021-10-20
PT3464266T (en) 2021-11-23
EP3464266A1 (en) 2019-04-10
US20220204474A1 (en) 2022-06-30
TW201808933A (en) 2018-03-16
DK3464266T3 (en) 2021-11-22
RU2018145860A3 (en) 2020-07-09
AU2017272505B9 (en) 2021-10-28
AU2017272505A8 (en) 2018-11-29
AU2017272505A1 (en) 2018-11-15
RU2018145860A (en) 2020-07-09
AU2017272505B2 (en) 2021-10-07
WO2017207481A8 (en) 2018-11-22
CN119367364A (en) 2025-01-28
IL263132B (en) 2022-04-01

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