MY188494A - High-growth enterovirus 71 strains and vaccines - Google Patents

High-growth enterovirus 71 strains and vaccines

Info

Publication number
MY188494A
MY188494A MYPI2017703328A MYPI2017703328A MY188494A MY 188494 A MY188494 A MY 188494A MY PI2017703328 A MYPI2017703328 A MY PI2017703328A MY PI2017703328 A MYPI2017703328 A MY PI2017703328A MY 188494 A MY188494 A MY 188494A
Authority
MY
Malaysia
Prior art keywords
vaccines
enterovirus
strains
growth
vaccine strains
Prior art date
Application number
MYPI2017703328A
Inventor
Min-Shi Lee
Original Assignee
National Health Res Inst
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by National Health Res Inst filed Critical National Health Res Inst
Publication of MY188494A publication Critical patent/MY188494A/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/12—Viral antigens
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55505—Inorganic adjuvants
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
    • C12N2770/00011—Details
    • C12N2770/32011—Picornaviridae
    • C12N2770/32311—Enterovirus
    • C12N2770/32321—Viruses as such, e.g. new isolates, mutants or their genomic sequences
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
    • C12N2770/00011—Details
    • C12N2770/32011—Picornaviridae
    • C12N2770/32311—Enterovirus
    • C12N2770/32322—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
    • C12N2770/00011—Details
    • C12N2770/32011—Picornaviridae
    • C12N2770/32311—Enterovirus
    • C12N2770/32334—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Virology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Microbiology (AREA)
  • Immunology (AREA)
  • Zoology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Mycology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)

Abstract

The present invention relates to adapted Enterovirus 71 (EV71) vaccine strains suitable for increased vaccine production for mammals. The EV71 vaccine strains contain at least one modified enterovirus protein that results in increased production of the EV71 virus from a mammalian host cell, such as a Vero cell. The present invention also relates to the vaccines produced from the adapted EV71 virus vaccine strains, and the producing method of the vaccines.
MYPI2017703328A 2015-03-09 2016-03-09 High-growth enterovirus 71 strains and vaccines MY188494A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201562130584P 2015-03-09 2015-03-09
PCT/US2016/021572 WO2016145087A1 (en) 2015-03-09 2016-03-09 High-growth enterovirus 71 strains and vaccines

Publications (1)

Publication Number Publication Date
MY188494A true MY188494A (en) 2021-12-15

Family

ID=56879095

Family Applications (1)

Application Number Title Priority Date Filing Date
MYPI2017703328A MY188494A (en) 2015-03-09 2016-03-09 High-growth enterovirus 71 strains and vaccines

Country Status (4)

Country Link
CN (1) CN108055827B (en)
MY (1) MY188494A (en)
TW (1) TWI638048B (en)
WO (1) WO2016145087A1 (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TWI775036B (en) 2020-01-14 2022-08-21 宏碁股份有限公司 Heat dissipation fan
CN111235114B (en) * 2020-01-22 2023-10-17 东莞市第八人民医院（东莞市儿童医院） EV71 replication-defective virus, and preparation method and application thereof

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH08173195A (en) * 1994-10-28 1996-07-09 Mitsubishi Kagaku B C L:Kk Method for discriminating types of enterovirus 71 type and coxsackie a group virus 16 type and dna probe and dna fragment used therefor
EP1479761A1 (en) * 2003-05-21 2004-11-24 PrimaGen Holding B.V. New enterovirus, vaccines, medicaments and diagnostic kits
US20090280531A1 (en) * 2008-05-06 2009-11-12 Academia Sinica Preparation of Soluble Capsid Proteins of Picornaviruses Using SUMO Fusion Technology
WO2012108840A1 (en) * 2011-02-08 2012-08-16 Temasek Life Sciences Laboratory Limited A novel expression cassette for efficient surface display of antigenic proteins
CN102220288B (en) * 2011-05-04 2013-07-17 中国科学院上海巴斯德研究所 Mouse-addapted enterovirus EV71 strain 573 and use thereof

Also Published As

Publication number Publication date
TWI638048B (en) 2018-10-11
CN108055827B (en) 2021-12-24
CN108055827A (en) 2018-05-18
WO2016145087A1 (en) 2016-09-15
TW201636424A (en) 2016-10-16

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