MY181129A - Site-directed modification of fviii - Google Patents

Site-directed modification of fviii

Info

Publication number
MY181129A
MY181129A MYPI2016001404A MYPI2016001404A MY181129A MY 181129 A MY181129 A MY 181129A MY PI2016001404 A MYPI2016001404 A MY PI2016001404A MY PI2016001404 A MYPI2016001404 A MY PI2016001404A MY 181129 A MY181129 A MY 181129A
Authority
MY
Malaysia
Prior art keywords
site
fviii
directed modification
polyethylene glycol
covalently bound
Prior art date
Application number
MYPI2016001404A
Inventor
Clark Q Pan
John E Murphy
Baisong Mei
Jonathan S Strauss
Jianmin Chen
Thomas Barnett
Hendri Tjandra
Liang Tang
Deqian Wang
Original Assignee
Bayer Healthcare Llc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer Healthcare Llc filed Critical Bayer Healthcare Llc
Priority to MYPI2016001404A priority Critical patent/MY181129A/en
Publication of MY181129A publication Critical patent/MY181129A/en

Links

Abstract

This invention relates to Factor VIII muteins that are covalently bound, at a predefined site that is not an N-terminal amine, to one or more biocompatible polymers such as polyethylene glycol. The mutein conjugates retain VIII procoagulant activity and have improved pharmacokinetic properties.
MYPI2016001404A 2007-05-18 2007-05-18 Site-directed modification of fviii MY181129A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
MYPI2016001404A MY181129A (en) 2007-05-18 2007-05-18 Site-directed modification of fviii

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
MYPI2016001404A MY181129A (en) 2007-05-18 2007-05-18 Site-directed modification of fviii

Publications (1)

Publication Number Publication Date
MY181129A true MY181129A (en) 2020-12-18

Family

ID=87569336

Family Applications (1)

Application Number Title Priority Date Filing Date
MYPI2016001404A MY181129A (en) 2007-05-18 2007-05-18 Site-directed modification of fviii

Country Status (1)

Country Link
MY (1) MY181129A (en)

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