MY151329A - Site-directed modification of fviii - Google Patents

Site-directed modification of fviii

Info

Publication number
MY151329A
MY151329A MYPI20070790A MY151329A MY 151329 A MY151329 A MY 151329A MY PI20070790 A MYPI20070790 A MY PI20070790A MY 151329 A MY151329 A MY 151329A
Authority
MY
Malaysia
Prior art keywords
site
fviii
directed modification
polyethylene glycol
covalently bound
Prior art date
Application number
Inventor
Clark Q Pan
John E Murphy
Mei Baisong
Jonathan S Strauss
Tjandra Hendri
Chen Jianmin
Barnett Thomas
Tang Liang
Wang Deqian
Original Assignee
Bayer Healthcare Llc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer Healthcare Llc filed Critical Bayer Healthcare Llc
Priority to MYPI20070790 priority Critical patent/MY151329A/en
Publication of MY151329A publication Critical patent/MY151329A/en

Links

Abstract

THIS INVENTION RELATES TO FACTOR VIII MUTEINS THAT ARE COVALENTLY BOUND, AT A PREDEFINED SITE THAT IS NOT AN N-TERMINAL AMINE, TO ONE OR MORE BIOCOMPATIBLE POLYMERS SUCH AS POLYETHYLENE GLYCOL. THE MUTEIN CONJUGATES RETAIN VIII PROCOAGULANT ACTIVITY AND HAVE IMPROVED PHARMACOKINETIC PROPERTIES.
MYPI20070790 2007-05-18 2007-05-18 Site-directed modification of fviii MY151329A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
MYPI20070790 MY151329A (en) 2007-05-18 2007-05-18 Site-directed modification of fviii

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
MYPI20070790 MY151329A (en) 2007-05-18 2007-05-18 Site-directed modification of fviii

Publications (1)

Publication Number Publication Date
MY151329A true MY151329A (en) 2014-05-15

Family

ID=52595651

Family Applications (1)

Application Number Title Priority Date Filing Date
MYPI20070790 MY151329A (en) 2007-05-18 2007-05-18 Site-directed modification of fviii

Country Status (1)

Country Link
MY (1) MY151329A (en)

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