MY177028A - Solid compositions of triglycerides and uses thereof - Google Patents
Solid compositions of triglycerides and uses thereofInfo
- Publication number
- MY177028A MY177028A MYPI2016000861A MYPI2016000861A MY177028A MY 177028 A MY177028 A MY 177028A MY PI2016000861 A MYPI2016000861 A MY PI2016000861A MY PI2016000861 A MYPI2016000861 A MY PI2016000861A MY 177028 A MY177028 A MY 177028A
- Authority
- MY
- Malaysia
- Prior art keywords
- solid compositions
- triglycerides
- triheptanoin
- spray
- drying
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
- A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
- A61K31/22—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin
- A61K31/23—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin of acids having a carboxyl group bound to a chain of seven or more carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/141—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
- A61K9/143—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with inorganic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/20—Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/20—Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids
- A61K31/201—Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids having one or two double bonds, e.g. oleic, linoleic acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/20—Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids
- A61K31/202—Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids having three or more double bonds, e.g. linolenic
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/141—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
- A61K9/146—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with organic macromolecular compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1611—Inorganic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1629—Organic macromolecular compounds
- A61K9/1652—Polysaccharides, e.g. alginate, cellulose derivatives; Cyclodextrin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1664—Compounds of unknown constitution, e.g. material from plants or animals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
- A61P21/02—Muscle relaxants, e.g. for tetanus or cramps
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Epidemiology (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Inorganic Chemistry (AREA)
- Pain & Pain Management (AREA)
- Neurology (AREA)
- Emergency Medicine (AREA)
- Zoology (AREA)
- Botany (AREA)
- Diabetes (AREA)
- Cardiology (AREA)
- Obesity (AREA)
- Neurosurgery (AREA)
- Urology & Nephrology (AREA)
- Hematology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Physical Education & Sports Medicine (AREA)
- Vascular Medicine (AREA)
- Biomedical Technology (AREA)
- Heart & Thoracic Surgery (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicinal Preparation (AREA)
- Fats And Perfumes (AREA)
- Coloring Foods And Improving Nutritive Qualities (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Fodder In General (AREA)
Abstract
The present invention includes solid compositions of triglycerides with one or more fatty acids, such as triheptanoin and glycerol phenylbutyrate, and therapeutic use thereof. The solid compositions can be prepared by spray-drying or other processes. Figure 1
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201361904369P | 2013-11-14 | 2013-11-14 |
Publications (1)
Publication Number | Publication Date |
---|---|
MY177028A true MY177028A (en) | 2020-09-02 |
Family
ID=53058066
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MYPI2016000861A MY177028A (en) | 2013-11-14 | 2014-11-14 | Solid compositions of triglycerides and uses thereof |
Country Status (18)
Country | Link |
---|---|
US (3) | US20160243071A1 (en) |
EP (2) | EP3782610A1 (en) |
JP (3) | JP2017501972A (en) |
KR (1) | KR102291310B1 (en) |
CN (2) | CN113181158A (en) |
AR (1) | AR099353A1 (en) |
AU (1) | AU2014348470B2 (en) |
CA (2) | CA3197154A1 (en) |
CL (1) | CL2016001130A1 (en) |
ES (1) | ES2833294T3 (en) |
IL (1) | IL245588B (en) |
MX (2) | MX2016006329A (en) |
MY (1) | MY177028A (en) |
PE (1) | PE20161024A1 (en) |
PH (1) | PH12016500821A1 (en) |
RU (1) | RU2016123169A (en) |
TW (1) | TWI640327B (en) |
WO (1) | WO2015073816A1 (en) |
Families Citing this family (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
PE20161024A1 (en) * | 2013-11-14 | 2016-11-10 | Ultragenyx Pharmaceutical Inc | SOLID COMPOSITIONS OF TRIGLYCERIDES AND USES OF THEM |
US20190076383A1 (en) * | 2017-09-08 | 2019-03-14 | Horizon Therapeutics, Llc | Methods for treating urea cycle disorders |
CA3110724A1 (en) | 2018-08-27 | 2020-03-05 | Exerkine Corporation | Method for treating lysosomal storage disease |
US11583542B2 (en) * | 2019-12-16 | 2023-02-21 | Amylyx Pharmaceuticals, Inc. | Compositions of bile acids and phenylbutyrate compounds |
CN113476408A (en) * | 2021-07-23 | 2021-10-08 | 兆科药业(广州)有限公司 | Phenylbutyrin granules and preparation method and application thereof |
Family Cites Families (21)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP2800610B2 (en) * | 1992-12-15 | 1998-09-21 | 不二製油株式会社 | Production method of oil-in-water emulsion |
JP3522843B2 (en) * | 1994-07-29 | 2004-04-26 | 昭和産業株式会社 | Lipo preparation |
ES2157422T3 (en) | 1995-02-07 | 2001-08-16 | Brusilow Entpr Llc | TRIGLICERIDS AND ETHYL ESTERS OF PHENYLALCANOIC ACID AND PHENYLALKYEN ACID USEFUL IN THE TREATMENT OF DIFFERENT DISORDERS. |
JPH08311480A (en) * | 1995-05-18 | 1996-11-26 | D H Ee Kodo Seisei Chushutsu Gijutsu Kenkyu Kumiai | Production of oil or fat comprising high-purify triacylglycerol and oil or fat composition containing highly unsaturated fatty acid |
JP4902906B2 (en) * | 1999-02-05 | 2012-03-21 | ベイラー リサーチ インスティテュート | Nutritional supplement or pharmaceutical preparation containing triglyceride containing fatty acid having 7 carbon atoms |
US8399515B2 (en) * | 2003-05-20 | 2013-03-19 | Baylor Research Institute | Five and fifteen carbon fatty acids for treating metabolic disorders and as nutritional supplements |
US20050058673A1 (en) * | 2003-09-09 | 2005-03-17 | 3M Innovative Properties Company | Antimicrobial compositions and methods |
US7141114B2 (en) * | 2004-06-30 | 2006-11-28 | Rec Silicon Inc | Process for producing a crystalline silicon ingot |
MX2007000304A (en) * | 2004-07-02 | 2007-06-15 | Baylor Res Inst | Glycogen or polysaccharide storage disease treatment method. |
KR20070113281A (en) * | 2005-03-10 | 2007-11-28 | 쓰리엠 이노베이티브 프로퍼티즈 컴파니 | Antimicrobial compositions and methods |
JP2008533048A (en) * | 2005-03-10 | 2008-08-21 | スリーエム イノベイティブ プロパティズ カンパニー | How to treat ear infections |
AU2007214127A1 (en) * | 2006-02-10 | 2007-08-16 | Sportscom Danmark Aps | Coated tablets, their methods of preparation, and related uses |
JP5296366B2 (en) * | 2007-10-29 | 2013-09-25 | 日清オイリオグループ株式会社 | Endurance improver for drugs and endurance drug |
PL3133396T3 (en) | 2008-04-29 | 2019-03-29 | Horizon Therapeutics, Llc | Methods of treatment using ammonia-scavenging drugs |
MX2012014520A (en) * | 2010-06-14 | 2013-03-05 | Baylor Res Inst | Triheptanoin diet for adult polyglucosan body disease (apbd) treatment. |
CN101919453B (en) * | 2010-08-16 | 2013-04-10 | 苏州市佳禾食品工业有限公司 | Medium carbon chain fatty acid powder grease and preparation method thereof |
KR20140094517A (en) | 2011-09-30 | 2014-07-30 | 하이페리온 쎄라퓨틱스, 인크. | Methods of therapeutic monitoring of nitrogen scavenging drugs |
TWI572352B (en) * | 2012-03-01 | 2017-03-01 | 波麥堤克藥學Smt有限公司 | Method for the preparation of triglycerides of medium-chain length fatty acids |
WO2013158616A1 (en) * | 2012-04-16 | 2013-10-24 | University Of Pittsburgh - Of The Commonwealth System Of Higher Education | Treatment of medium-chain acyl-coa dehydrogenase deficiency |
BR112015013349A2 (en) | 2012-12-13 | 2017-07-11 | Baylor Res Institute At Dallas | trieptanoin for the treatment of glucose transporter deficiency 1 |
PE20161024A1 (en) * | 2013-11-14 | 2016-11-10 | Ultragenyx Pharmaceutical Inc | SOLID COMPOSITIONS OF TRIGLYCERIDES AND USES OF THEM |
-
2014
- 2014-11-14 PE PE2016000621A patent/PE20161024A1/en not_active Application Discontinuation
- 2014-11-14 JP JP2016529444A patent/JP2017501972A/en active Pending
- 2014-11-14 WO PCT/US2014/065693 patent/WO2015073816A1/en active Application Filing
- 2014-11-14 KR KR1020167013964A patent/KR102291310B1/en active IP Right Grant
- 2014-11-14 US US14/419,601 patent/US20160243071A1/en not_active Abandoned
- 2014-11-14 CN CN202110316004.0A patent/CN113181158A/en active Pending
- 2014-11-14 EP EP20196269.3A patent/EP3782610A1/en active Pending
- 2014-11-14 MX MX2016006329A patent/MX2016006329A/en unknown
- 2014-11-14 CN CN201480064471.7A patent/CN105764497A/en active Pending
- 2014-11-14 TW TW103139665A patent/TWI640327B/en active
- 2014-11-14 RU RU2016123169A patent/RU2016123169A/en unknown
- 2014-11-14 CA CA3197154A patent/CA3197154A1/en active Pending
- 2014-11-14 CA CA2929688A patent/CA2929688C/en active Active
- 2014-11-14 AU AU2014348470A patent/AU2014348470B2/en active Active
- 2014-11-14 MY MYPI2016000861A patent/MY177028A/en unknown
- 2014-11-14 AR ARP140104294A patent/AR099353A1/en not_active Application Discontinuation
- 2014-11-14 ES ES14861440T patent/ES2833294T3/en active Active
- 2014-11-14 EP EP14861440.7A patent/EP3068383B1/en active Active
-
2016
- 2016-05-03 PH PH12016500821A patent/PH12016500821A1/en unknown
- 2016-05-10 IL IL245588A patent/IL245588B/en unknown
- 2016-05-11 CL CL2016001130A patent/CL2016001130A1/en unknown
- 2016-05-13 MX MX2021001790A patent/MX2021001790A/en unknown
-
2019
- 2019-06-19 US US16/445,557 patent/US20200069631A1/en not_active Abandoned
-
2020
- 2020-03-11 JP JP2020041943A patent/JP2020111585A/en active Pending
-
2022
- 2022-05-16 JP JP2022080251A patent/JP2022107017A/en active Pending
-
2023
- 2023-02-10 US US18/167,551 patent/US20230181513A1/en active Pending
Also Published As
Publication number | Publication date |
---|---|
TW201609189A (en) | 2016-03-16 |
CN113181158A (en) | 2021-07-30 |
EP3068383A4 (en) | 2017-11-08 |
JP2022107017A (en) | 2022-07-20 |
US20160243071A1 (en) | 2016-08-25 |
PH12016500821A1 (en) | 2016-06-13 |
JP2020111585A (en) | 2020-07-27 |
US20200069631A1 (en) | 2020-03-05 |
KR20160084407A (en) | 2016-07-13 |
AU2014348470A1 (en) | 2016-05-26 |
EP3782610A1 (en) | 2021-02-24 |
US20230181513A1 (en) | 2023-06-15 |
ES2833294T3 (en) | 2021-06-14 |
AR099353A1 (en) | 2016-07-20 |
TWI640327B (en) | 2018-11-11 |
CA3197154A1 (en) | 2015-05-21 |
IL245588B (en) | 2021-08-31 |
PE20161024A1 (en) | 2016-11-10 |
CN105764497A (en) | 2016-07-13 |
CL2016001130A1 (en) | 2017-01-20 |
IL245588A0 (en) | 2016-06-30 |
RU2016123169A (en) | 2017-12-19 |
MX2016006329A (en) | 2016-09-06 |
MX2021001790A (en) | 2021-04-19 |
EP3068383A1 (en) | 2016-09-21 |
EP3068383B1 (en) | 2020-09-16 |
CA2929688A1 (en) | 2015-05-21 |
KR102291310B1 (en) | 2021-08-23 |
JP2017501972A (en) | 2017-01-19 |
AU2014348470B2 (en) | 2020-01-30 |
WO2015073816A1 (en) | 2015-05-21 |
CA2929688C (en) | 2023-06-13 |
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