MY170152A - Ethynyl derivative as modulators of mglur5 receptor activity - Google Patents
Ethynyl derivative as modulators of mglur5 receptor activityInfo
- Publication number
- MY170152A MY170152A MYPI2015000492A MYPI2015000492A MY170152A MY 170152 A MY170152 A MY 170152A MY PI2015000492 A MYPI2015000492 A MY PI2015000492A MY PI2015000492 A MYPI2015000492 A MY PI2015000492A MY 170152 A MY170152 A MY 170152A
- Authority
- MY
- Malaysia
- Prior art keywords
- modulators
- receptor activity
- mglur5 receptor
- ethynyl derivative
- disease
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D213/81—Amides; Imides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Psychology (AREA)
- Pain & Pain Management (AREA)
- Psychiatry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Pyridine Compounds (AREA)
- Epidemiology (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP12189015 | 2012-10-18 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MY170152A true MY170152A (en) | 2019-07-09 |
Family
ID=47049073
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MYPI2015000492A MY170152A (en) | 2012-10-18 | 2013-10-15 | Ethynyl derivative as modulators of mglur5 receptor activity |
Country Status (25)
| Country | Link |
|---|---|
| US (1) | US9328070B2 (es) |
| EP (1) | EP2909179B1 (es) |
| JP (1) | JP5989253B2 (es) |
| KR (1) | KR101656634B1 (es) |
| CN (1) | CN104718191B (es) |
| AR (1) | AR093043A1 (es) |
| AU (1) | AU2013333984B2 (es) |
| BR (1) | BR112015007991A2 (es) |
| CA (1) | CA2882484A1 (es) |
| CL (1) | CL2015000708A1 (es) |
| CR (1) | CR20150143A (es) |
| EA (1) | EA025668B1 (es) |
| ES (1) | ES2599509T3 (es) |
| HK (1) | HK1208032A1 (es) |
| IL (1) | IL237116A (es) |
| MA (1) | MA38011B1 (es) |
| MX (1) | MX2015004086A (es) |
| MY (1) | MY170152A (es) |
| PE (1) | PE20150628A1 (es) |
| PH (1) | PH12015500496A1 (es) |
| SG (1) | SG11201501375YA (es) |
| TW (1) | TWI468393B (es) |
| UA (1) | UA114934C2 (es) |
| WO (1) | WO2014060394A1 (es) |
| ZA (1) | ZA201500896B (es) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2879489A1 (en) * | 2012-10-18 | 2014-04-24 | F.Hoffmann-La Roche Ag | Ethynyl derivatives as modulators of mglur5 receptor activity |
| JP6761821B2 (ja) | 2015-07-15 | 2020-09-30 | エフ．ホフマン−ラ ロシュ アーゲーＦ． Ｈｏｆｆｍａｎｎ−Ｌａ Ｒｏｃｈｅ Ａｋｔｉｅｎｇｅｓｅｌｌｓｃｈａｆｔ | 代謝性グルタミン酸受容体モジュレーターとしてのエチニル誘導体 |
| SG11201811829QA (en) | 2016-07-18 | 2019-02-27 | Hoffmann La Roche | Ethynyl derivatives |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| TW544448B (en) * | 1997-07-11 | 2003-08-01 | Novartis Ag | Pyridine derivatives |
| US8853392B2 (en) * | 2007-06-03 | 2014-10-07 | Vanderbilt University | Benzamide mGluR5 positive allosteric modulators and methods of making and using same |
| NZ581817A (en) * | 2007-06-03 | 2012-05-25 | Univ Vanderbilt | Benzamide mglur5 positive allosteric modulators and methods of making and using same |
| EP2190487A1 (en) * | 2007-09-28 | 2010-06-02 | E. I. du Pont de Nemours and Company | Ionic liquid stabilizer compositions |
| TW201124391A (en) * | 2009-10-20 | 2011-07-16 | Lundbeck & Co As H | 2-substituted-ethynylthiazole derivatives and uses of same |
| US8389536B2 (en) * | 2009-10-27 | 2013-03-05 | Hoffmann-La Roche Inc. | Positive allosteric modulators (PAM) |
| US8772300B2 (en) * | 2011-04-19 | 2014-07-08 | Hoffmann-La Roche Inc. | Phenyl or pyridinyl-ethynyl derivatives |
-
2013
- 2013-10-15 KR KR1020157009546A patent/KR101656634B1/ko active IP Right Grant
- 2013-10-15 JP JP2015537221A patent/JP5989253B2/ja not_active Expired - Fee Related
- 2013-10-15 MY MYPI2015000492A patent/MY170152A/en unknown
- 2013-10-15 WO PCT/EP2013/071493 patent/WO2014060394A1/en active Application Filing
- 2013-10-15 CA CA2882484A patent/CA2882484A1/en not_active Abandoned
- 2013-10-15 CN CN201380053650.6A patent/CN104718191B/zh not_active Expired - Fee Related
- 2013-10-15 BR BR112015007991A patent/BR112015007991A2/pt active Search and Examination
- 2013-10-15 AU AU2013333984A patent/AU2013333984B2/en not_active Ceased
- 2013-10-15 MX MX2015004086A patent/MX2015004086A/es unknown
- 2013-10-15 EA EA201590722A patent/EA025668B1/ru not_active IP Right Cessation
- 2013-10-15 UA UAA201504379A patent/UA114934C2/uk unknown
- 2013-10-15 PE PE2015000395A patent/PE20150628A1/es not_active Application Discontinuation
- 2013-10-15 ES ES13776810.7T patent/ES2599509T3/es active Active
- 2013-10-15 EP EP13776810.7A patent/EP2909179B1/en not_active Not-in-force
- 2013-10-15 SG SG11201501375YA patent/SG11201501375YA/en unknown
- 2013-10-17 TW TW102137557A patent/TWI468393B/zh not_active IP Right Cessation
- 2013-10-17 AR ARP130103765A patent/AR093043A1/es unknown
-
2015
- 2015-02-05 IL IL237116A patent/IL237116A/en not_active IP Right Cessation
- 2015-02-06 ZA ZA2015/00896A patent/ZA201500896B/en unknown
- 2015-03-06 PH PH12015500496A patent/PH12015500496A1/en unknown
- 2015-03-18 CR CR20150143A patent/CR20150143A/es unknown
- 2015-03-20 CL CL2015000708A patent/CL2015000708A1/es unknown
- 2015-04-17 US US14/689,366 patent/US9328070B2/en not_active Expired - Fee Related
- 2015-04-17 MA MA38011A patent/MA38011B1/fr unknown
- 2015-09-08 HK HK15108720.3A patent/HK1208032A1/zh not_active IP Right Cessation
Also Published As
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| PH12015500398B1 (en) | Ethynyl derivatives as modulators of mglur5 receptor activity | |
| MX2014000536A (es) | Compuestos de 4-piperidinilo para usarse como inhibidores de tanquirasa. | |
| EA201500298A1 (ru) | Алкоксипиразолы в качестве активаторов растворимой гуанилатциклазы | |
| NI201100016A (es) | Formulaciones farmacéuticas que contienen ligandos de receptores de dopamina. | |
| MX2021010046A (es) | Nueva composicion terapeutica que contiene ingrediente activo de apomorfinas. | |
| MY183111A (en) | 3-(heteroaryl-amino)-1,2,3,4-tetrahydro-9h-carbazole derivatives and their use as prostaglandin d2 receptor modulators | |
| PH12015502692B1 (en) | Ethynyl derivatives as metabotropic glutamate receptor antagonists | |
| PH12015500346A1 (en) | Ethynyl derivatives as modulators of mglur5 receptor activity | |
| MX2013006768A (es) | Moduladores de receptor de glucagon. | |
| PH12015500496A1 (en) | Ethynyl derivatives as modulators of mglur5 receptor activity | |
| IN2013DN02555A (es) | ||
| WO2015138276A3 (en) | Retinoic acid receptor-related orphan receptor modulators and uses thereof | |
| MX2013001988A (es) | Compuestos de heterociclilo comoligandos del receptor h3 de la histamina | |
| MX2014000855A (es) | Moduladores receptores de glucagon de quinolinilo. | |
| PH12017502128A1 (en) | Ethynyl derivatives | |
| TH167680B (th) | อนุพันธ์เอไทนิลในฐานะโมดูเลเตอร์ของฤทธิ์ของ mglur5 รีเซปเตอร์ | |
| UA106839C2 (uk) | Модулятори глюкагон рецептора | |
| WO2012138254A3 (ru) | Производные 4,4 '-бифенил амидов, обладающие фармакологической активностью, и лекарственные средства на их основе |