MY148979A - Method for the production of methionine by culturing a microorganism modified to enhance production of cysteine - Google Patents
Method for the production of methionine by culturing a microorganism modified to enhance production of cysteineInfo
- Publication number
- MY148979A MY148979A MYPI20070009A MYPI20070009A MY148979A MY 148979 A MY148979 A MY 148979A MY PI20070009 A MYPI20070009 A MY PI20070009A MY PI20070009 A MYPI20070009 A MY PI20070009A MY 148979 A MY148979 A MY 148979A
- Authority
- MY
- Malaysia
- Prior art keywords
- production
- methionine
- cysteine
- culturing
- microorganism
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P13/00—Preparation of nitrogen-containing organic compounds
- C12P13/04—Alpha- or beta- amino acids
- C12P13/12—Methionine; Cysteine; Cystine
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P13/00—Preparation of nitrogen-containing organic compounds
- C12P13/04—Alpha- or beta- amino acids
- C12P13/06—Alanine; Leucine; Isoleucine; Serine; Homoserine
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Zoology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Wood Science & Technology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Microbiology (AREA)
- General Chemical & Material Sciences (AREA)
- Biotechnology (AREA)
- Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Abstract
THE PRESENT INVENTION RELATES TO A PROCESS FOR THE PRODUCTION OF METHIONINE OR ITS DERIVATIVES BY CULTURING A MICROORGANISM IN AN APPROPRIATE CULTURE MEDIUM COMPRISING A SOURCE OF CARBON AND A SOURCE OF SULFUR. THE MICROORGANISM CLAIMED IS MODIFIED IN A WAY THAT THE PRODUCTION OF CYSTEINE AND/OR C1 UNITS IS ENHANCED AND/OR THE TRANSFER POTENTIAL OF THE C1 UNITS ON HOMOCYSTEINE IS INCREASED OR OPTIMIZED. THE ISOLATION OF METHIONINE OR ITS DERIVATES FROM THE FERMENTATION MEDIUM IS ALSO CLAIMED.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
PCT/EP2006/050033 WO2007077041A1 (en) | 2006-01-04 | 2006-01-04 | Process for the preparation of methionine and its precursors homoserine or succinylhomoserine employing a microorganism with enhanced sulfate permease expression |
Publications (1)
Publication Number | Publication Date |
---|---|
MY148979A true MY148979A (en) | 2013-06-28 |
Family
ID=37508334
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MYPI20070009A MY148979A (en) | 2006-01-04 | 2007-01-04 | Method for the production of methionine by culturing a microorganism modified to enhance production of cysteine |
Country Status (11)
Country | Link |
---|---|
US (2) | US8389250B2 (en) |
EP (2) | EP2314710B1 (en) |
JP (1) | JP5172697B2 (en) |
CN (1) | CN101351558B (en) |
AR (1) | AR058914A1 (en) |
BR (1) | BRPI0620880B1 (en) |
DK (1) | DK2314710T3 (en) |
ES (1) | ES2459617T3 (en) |
MY (1) | MY148979A (en) |
PL (1) | PL1969130T3 (en) |
WO (1) | WO2007077041A1 (en) |
Families Citing this family (75)
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JP4110641B2 (en) | 1998-11-17 | 2008-07-02 | 味の素株式会社 | Method for producing L-methionine by fermentation |
WO2007077041A1 (en) * | 2006-01-04 | 2007-07-12 | Metabolic Explorer | Process for the preparation of methionine and its precursors homoserine or succinylhomoserine employing a microorganism with enhanced sulfate permease expression |
EP2019868A2 (en) * | 2006-05-24 | 2009-02-04 | Evonik Degussa GmbH | Process for the preparation of l-methionine |
KR100905381B1 (en) | 2006-07-28 | 2009-06-30 | 씨제이제일제당 (주) | Microorganism producing l-methionine precursor and method of producing l-methionine and organic acid from the l-methionine precurosr |
WO2009043372A1 (en) | 2007-10-02 | 2009-04-09 | Metabolic Explorer | Increasing methionine yield |
KR101241182B1 (en) | 2008-03-19 | 2013-03-13 | 히라따기꼬오 가부시키가이샤 | Work inspector and carrier |
US9005952B2 (en) | 2008-04-04 | 2015-04-14 | Cj Cheiljedang Corporation | Microorganism producing L-methionine precursor and the method of producing L-methionine precursor using the microorganism |
US7851180B2 (en) * | 2008-04-04 | 2010-12-14 | Cj Cheiljedang Corporation | Microorganism producing L-methionine precursor and the method of producing L-methionine precursor using the microorganism |
WO2010022763A1 (en) * | 2008-08-25 | 2010-03-04 | Metabolic Explorer | Method for the preparation of 2-hydroxy-isobutyrate |
WO2010020290A1 (en) * | 2008-08-22 | 2010-02-25 | Metabolic Explorer | Producing methionine without n-acetyl methionine |
WO2010020289A1 (en) | 2008-08-22 | 2010-02-25 | Metabolic Explorer | Production of n-acetylated sulphur-containing amino acids with microorganisms having enhanced n-acetyltransferase enzymatic activity |
KR101827230B1 (en) | 2008-12-31 | 2018-02-07 | 메타볼릭 익스플로러 | Method for the preparation of diols |
JP2012223092A (en) * | 2009-08-28 | 2012-11-15 | Ajinomoto Co Inc | Method for producing l-amino acid |
US8609396B2 (en) * | 2009-08-28 | 2013-12-17 | Cj Cheiljedang Corporation | Microorganism producing O-acetyl-homoserine and the method of producing O-acetyl-homoserine using the microorganism |
RU2009136544A (en) * | 2009-10-05 | 2011-04-10 | Закрытое акционерное общество "Научно-исследовательский институт "Аджиномото-Генетика" (ЗАО АГРИ) (RU) | METHOD FOR PRODUCING L-CISTEINE USING THE ENTEROBACTERIACEAE FAMILY BACTERIA |
FR2951195B1 (en) | 2009-10-14 | 2014-01-31 | Roquette Freres | COMPOSITION RICH IN METHIONINE FOR ANIMAL FEEDING |
JP5817529B2 (en) | 2009-11-30 | 2015-11-18 | 味の素株式会社 | L-cysteine producing bacterium and method for producing L-cysteine |
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KR101208267B1 (en) * | 2010-10-20 | 2012-12-04 | 씨제이제일제당 (주) | O-phosphoserine sulfhydrylase variants |
AR083468A1 (en) | 2010-10-25 | 2013-02-27 | Metabolic Explorer Sa | INCREASING NADPH'S AVAILABILITY FOR METIONIN PRODUCTION |
WO2012090021A1 (en) | 2010-12-30 | 2012-07-05 | Metabolic Explorer | Recombinant microorganism for the fermentative production of methionine |
CN103429748B (en) * | 2010-12-30 | 2016-01-06 | 代谢探索者公司 | The fermentation of hydroxy analogue of methionine (MHA) produces |
EP2479279A1 (en) | 2011-01-20 | 2012-07-25 | Evonik Degussa GmbH | Method for producing sulphuric amino acids by means of fermentation |
JP2014087259A (en) | 2011-02-22 | 2014-05-15 | Ajinomoto Co Inc | L-cysteine-producing bacterium, and production method of l-cysteine |
US9234223B2 (en) | 2011-04-01 | 2016-01-12 | Ajinomoto Co., Inc. | Method for producing L-cysteine |
WO2012137689A1 (en) | 2011-04-01 | 2012-10-11 | 味の素株式会社 | Method for producing l-cysteine |
AR086790A1 (en) * | 2011-06-29 | 2014-01-22 | Metabolic Explorer Sa | A MICROORGANISM FOR THE PRODUCTION OF METIONIN WITH IMPORTATION OF IMPROVED GLUCOSE |
EP2540834A1 (en) | 2011-06-29 | 2013-01-02 | Metabolic Explorer | Method for the preparation of 1,3-propanediol |
US9410164B2 (en) | 2011-10-11 | 2016-08-09 | Metabolic Explorer | Biosynthesis pathway for prenol in a recombinant microorganism |
FR2983870B1 (en) | 2011-12-08 | 2015-07-17 | Roquette Freres | METHIONINE COMPOSITION FOR ANIMAL FEEDING |
EP2628792A1 (en) | 2012-02-17 | 2013-08-21 | Evonik Industries AG | Cell with reduced ppGppase activity |
EP2647718A3 (en) | 2012-04-06 | 2014-12-24 | Metabolic Explorer | Process for producing 5-aminopentanoate empolying a recombinant microorganism |
CN104411821B (en) | 2012-06-18 | 2017-08-08 | 代谢探索者公司 | Recombinant microorganism for fermenting and producing methionine |
EP2700715B1 (en) | 2012-08-20 | 2018-07-25 | Evonik Degussa GmbH | Method for manufacturing L-amino acids using improved strains of the enterobacteriaceae family by means of fermentation |
WO2014049382A2 (en) | 2012-09-26 | 2014-04-03 | Metabolic Explorer | Ethylenediamine fermentative production by a recombinant microorganism |
WO2014071182A1 (en) | 2012-11-01 | 2014-05-08 | Massachusetts Institute Of Technology | Directed evolution of synthetic gene cluster |
PE20150681A1 (en) | 2013-05-13 | 2015-05-15 | Ajinomoto Kk | METHOD TO PRODUCE L-AMINO ACIDS |
PL3039153T3 (en) | 2013-08-30 | 2019-02-28 | Evonik Degussa Gmbh | Microorganism for methionine production with improved methionine synthase activity and methionine efflux |
JP6459962B2 (en) | 2013-10-21 | 2019-01-30 | 味の素株式会社 | Method for producing L-amino acid |
JP6519476B2 (en) | 2013-10-23 | 2019-05-29 | 味の素株式会社 | Production method of target substance |
JP6393898B2 (en) * | 2014-08-03 | 2018-09-26 | 国立大学法人 奈良先端科学技術大学院大学 | Yeast culture method |
CA2959563A1 (en) | 2014-09-01 | 2016-03-10 | Metabolic Explorer | Method and microorganism for methionine production by fermentation with improved methionine efflux |
EP3050970B1 (en) | 2015-01-28 | 2019-09-18 | Metabolic Explorer | Modified microorganism for optimized production of 1,4-butanediol |
US10858675B2 (en) | 2015-04-07 | 2020-12-08 | Metabolic Explorer | Modified microorganism for the optimized production of 2,4-dihydroxybutyrate with enhanced 2,4-dihydroxybutyrate efflux |
EP3095868A1 (en) | 2015-05-19 | 2016-11-23 | Evonik Degussa GmbH | Methionine production |
EP3298156A1 (en) | 2015-07-10 | 2018-03-28 | Evonik Degussa GmbH | Amino acid production |
EP3322679A4 (en) | 2015-07-13 | 2019-07-10 | Pivot Bio, Inc. | Methods and compositions for improving plant traits |
US20180223319A1 (en) | 2015-08-07 | 2018-08-09 | Evonik Degussa Gmbh | Protein thiocarboxylate-dependent l-methionine production by fermentation |
WO2017042602A1 (en) | 2015-09-10 | 2017-03-16 | Metabolic Explorer | New lactaldehyde reductases for the production of 1,2-propanediol |
FR3041658B1 (en) | 2015-09-30 | 2017-10-20 | Arkema France | PROCESS FOR PRODUCING L-METHIONINE |
FR3041659B1 (en) | 2015-09-30 | 2017-10-20 | Arkema France | PROCESS FOR PRODUCING L-METHIONINE |
EP3359664A4 (en) | 2015-10-05 | 2019-03-20 | Massachusetts Institute Of Technology | Nitrogen fixation using refactored nif clusters |
CN108291243A (en) | 2015-11-27 | 2018-07-17 | 赢创德固赛有限公司 | The method for producing l-methionine |
KR20180093981A (en) | 2016-01-08 | 2018-08-22 | 에보니크 데구사 게엠베하 | Method for producing L-methionine by fermentative production |
EP3296404A1 (en) | 2016-09-15 | 2018-03-21 | Evonik Degussa GmbH | Modified microorganism for production of methionine |
CN110799474B (en) | 2017-01-12 | 2022-07-26 | 皮沃特生物公司 | Methods and compositions for improving plant traits |
JP7066977B2 (en) | 2017-04-03 | 2022-05-16 | 味の素株式会社 | Manufacturing method of L-amino acid |
BR112020000552A2 (en) | 2017-07-11 | 2020-07-21 | Adisseo France S.A.S. | methionine-producing yeast |
KR20200044015A (en) * | 2017-08-09 | 2020-04-28 | 피벗 바이오, 인크. | Methods and compositions for improving genetically engineered microorganisms |
EP3470512A1 (en) | 2017-10-10 | 2019-04-17 | Metabolic Explorer | Mutant phosphoserine aminotransferase for the conversion of homoserine into 4-hydroxy-2-ketobutyrate |
CN111587287A (en) | 2017-10-25 | 2020-08-25 | 皮沃特生物股份有限公司 | Methods and compositions for improved nitrogen-fixing engineered microorganisms |
CN112739668A (en) | 2018-06-27 | 2021-04-30 | 皮沃特生物股份有限公司 | Agricultural compositions comprising reconstituted nitrogen-fixing microorganisms |
WO2020067487A1 (en) | 2018-09-28 | 2020-04-02 | Ajinomoto Co., Inc. | Method for producing l-methionine using a bacterium |
WO2020071538A1 (en) | 2018-10-05 | 2020-04-09 | Ajinomoto Co., Inc. | Method for producing target substance by bacterial fermentation |
WO2020198258A1 (en) * | 2019-03-26 | 2020-10-01 | Zymergen Inc. | Engineered biosynthetic pathways for production of l-homocysteine by fermentation |
KR102472559B1 (en) * | 2019-06-28 | 2022-12-01 | 씨제이제일제당 주식회사 | A method of producing sulfur-containing amino acids and derivatives thereof |
KR102472558B1 (en) * | 2019-06-28 | 2022-12-01 | 씨제이제일제당 주식회사 | A method of producing sulfur-containing amino acids and derivatives thereof |
CN113388630B (en) * | 2020-03-11 | 2022-07-26 | 华东理工大学 | Construction method and application of recombinant escherichia coli for synthesizing L-cysteine |
CN112592924B (en) * | 2020-12-28 | 2022-07-01 | 宁夏伊品生物科技股份有限公司 | YH66_10325 gene-modified recombinant strain producing L-isoleucine as well as construction method and application thereof |
CN114350586B (en) * | 2022-01-24 | 2023-07-28 | 浙江工业大学 | Genetically engineered bacterium for high-yield of L-cysteine, construction method and application |
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JP2000157267A (en) | 1998-11-24 | 2000-06-13 | Ajinomoto Co Inc | VARIATION TYPE metJ GENE AND PRODUCTION OF L-METHIONINE |
US6831165B1 (en) * | 1999-06-25 | 2004-12-14 | Basf Aktiengesellschaft | Corynebacterium glutamicum genes encoding proteins involved in homeostasis and adaptation |
AU2223601A (en) * | 1999-12-24 | 2001-07-09 | Ajinomoto Co., Inc. | Process for producing l-amino acid and novel gene |
US7220571B2 (en) * | 2000-09-28 | 2007-05-22 | Archer-Daniels-Midland Company | Escherichia coli strains which over-produce L-threonine and processes for the production of L-threonine by fermentation |
ES2269712T3 (en) * | 2001-07-11 | 2007-04-01 | Degussa Gmbh | PROCESS FOR THE PREPARATION OF L-AMINO ACIDS THAT USES ENVIRONMENTAL FAMILY STRAPS. |
EP1686184B1 (en) | 2001-07-11 | 2008-08-27 | Evonik Degussa GmbH | Process for the preparation of L-threonine using strains of the enterobacteriaceae family |
US7160711B2 (en) * | 2001-08-06 | 2007-01-09 | Degussa Ag | Coryneform bacteria which produce chemical compounds I |
DE10239308A1 (en) * | 2002-08-27 | 2004-03-11 | Basf Ag | Fermentative production of sulfur-containing fine chemicals, useful e.g. as feed additive, by culturing bacteria containing heterologous sequence for methionine synthase |
CA2510475A1 (en) | 2002-12-20 | 2004-07-08 | Metanomics Gmbh & Co. Kgaa | Method of producing amino acids in transgenic plants comprising expressing a nucleic acid encoding a threonine decomposing protein |
DE10305774A1 (en) | 2003-02-06 | 2004-08-26 | Consortium für elektrochemische Industrie GmbH | Process for the fermentative production of L-methionine |
MXPA05008857A (en) | 2003-02-18 | 2006-03-09 | Metabolic Explorer Sa | Method for the production of evolved microorganisms which permit the generation or modification of metabolic pathways. |
WO2004108894A2 (en) | 2003-05-30 | 2004-12-16 | Microbia, Inc. | Methods and compositions for amino acid production |
RU2275425C2 (en) | 2003-11-03 | 2006-04-27 | Закрытое акционерное общество "Научно-исследовательский институт Аджиномото-Генетика" (ЗАО АГРИ) | Bacterium belonging to genus escherichia as producer of l-cysteine and method for preparing l-cysteine |
DE10359668A1 (en) | 2003-12-18 | 2005-07-14 | Basf Ag | Process for the preparation of methionine |
DE102004009454A1 (en) * | 2004-02-27 | 2005-09-15 | Degussa Ag | Fermentative production of L-amino acids, especially methionine, useful e.g. in animal nutrition, by culturing bacteria in which components of the methionine uptake system are suppressed |
DE102004013503A1 (en) | 2004-03-18 | 2005-10-06 | Degussa Ag | Process for producing L-amino acids using coryneform bacteria |
WO2005111202A1 (en) * | 2004-05-12 | 2005-11-24 | Metabolic Explorer | Recombinant enzyme with altered feedback sensitivity |
WO2006082254A2 (en) * | 2005-02-07 | 2006-08-10 | Metabolic Explorer | Microorganisms comprising enzymes expressed with low gamma-elimination activity |
JP2009501550A (en) * | 2005-07-18 | 2009-01-22 | ビーエーエスエフ ソシエタス・ヨーロピア | Methionine-producing recombinant microorganism |
WO2007077041A1 (en) * | 2006-01-04 | 2007-07-12 | Metabolic Explorer | Process for the preparation of methionine and its precursors homoserine or succinylhomoserine employing a microorganism with enhanced sulfate permease expression |
-
2006
- 2006-01-04 WO PCT/EP2006/050033 patent/WO2007077041A1/en active Application Filing
- 2006-01-04 DK DK10187418.8T patent/DK2314710T3/en active
- 2006-01-04 CN CN2006800503269A patent/CN101351558B/en not_active Expired - Fee Related
- 2006-01-04 BR BRPI0620880A patent/BRPI0620880B1/en not_active IP Right Cessation
- 2006-01-04 EP EP10187418.8A patent/EP2314710B1/en not_active Not-in-force
- 2006-01-04 EP EP06707666.1A patent/EP1969130B1/en not_active Not-in-force
- 2006-01-04 JP JP2008548953A patent/JP5172697B2/en not_active Expired - Fee Related
- 2006-01-04 US US12/159,846 patent/US8389250B2/en active Active
- 2006-01-04 PL PL06707666T patent/PL1969130T3/en unknown
- 2006-01-04 ES ES06707666.1T patent/ES2459617T3/en active Active
-
2007
- 2007-01-04 AR ARP070100036A patent/AR058914A1/en not_active Application Discontinuation
- 2007-01-04 MY MYPI20070009A patent/MY148979A/en unknown
-
2013
- 2013-01-09 US US13/737,188 patent/US9187775B2/en not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
AR058914A1 (en) | 2008-03-05 |
JP5172697B2 (en) | 2013-03-27 |
US20080311632A1 (en) | 2008-12-18 |
EP1969130A1 (en) | 2008-09-17 |
PL1969130T3 (en) | 2014-08-29 |
JP2009521939A (en) | 2009-06-11 |
EP2314710A3 (en) | 2012-02-22 |
DK2314710T3 (en) | 2016-06-13 |
EP1969130B1 (en) | 2014-03-12 |
BRPI0620880B1 (en) | 2018-10-09 |
EP2314710A2 (en) | 2011-04-27 |
CN101351558A (en) | 2009-01-21 |
CN101351558B (en) | 2013-08-14 |
US20130183726A1 (en) | 2013-07-18 |
BRPI0620880A2 (en) | 2012-09-18 |
ES2459617T3 (en) | 2014-05-12 |
US9187775B2 (en) | 2015-11-17 |
US8389250B2 (en) | 2013-03-05 |
WO2007077041A1 (en) | 2007-07-12 |
EP2314710B1 (en) | 2016-03-30 |
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