MY148979A - Method for the production of methionine by culturing a microorganism modified to enhance production of cysteine - Google Patents

Method for the production of methionine by culturing a microorganism modified to enhance production of cysteine

Info

Publication number
MY148979A
MY148979A MYPI20070009A MYPI20070009A MY148979A MY 148979 A MY148979 A MY 148979A MY PI20070009 A MYPI20070009 A MY PI20070009A MY PI20070009 A MYPI20070009 A MY PI20070009A MY 148979 A MY148979 A MY 148979A
Authority
MY
Malaysia
Prior art keywords
production
methionine
cysteine
culturing
microorganism
Prior art date
Application number
MYPI20070009A
Inventor
Figge Rainer
Lux Fabien
Raynaud Celine
Chateau Michel
Soucaille Philippe
Original Assignee
Metabolic Explorer Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Metabolic Explorer Sa filed Critical Metabolic Explorer Sa
Publication of MY148979A publication Critical patent/MY148979A/en

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Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P13/00Preparation of nitrogen-containing organic compounds
    • C12P13/04Alpha- or beta- amino acids
    • C12P13/12Methionine; Cysteine; Cystine
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P13/00Preparation of nitrogen-containing organic compounds
    • C12P13/04Alpha- or beta- amino acids
    • C12P13/06Alanine; Leucine; Isoleucine; Serine; Homoserine

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  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Microbiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biotechnology (AREA)
  • Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)

Abstract

THE PRESENT INVENTION RELATES TO A PROCESS FOR THE PRODUCTION OF METHIONINE OR ITS DERIVATIVES BY CULTURING A MICROORGANISM IN AN APPROPRIATE CULTURE MEDIUM COMPRISING A SOURCE OF CARBON AND A SOURCE OF SULFUR. THE MICROORGANISM CLAIMED IS MODIFIED IN A WAY THAT THE PRODUCTION OF CYSTEINE AND/OR C1 UNITS IS ENHANCED AND/OR THE TRANSFER POTENTIAL OF THE C1 UNITS ON HOMOCYSTEINE IS INCREASED OR OPTIMIZED. THE ISOLATION OF METHIONINE OR ITS DERIVATES FROM THE FERMENTATION MEDIUM IS ALSO CLAIMED.
MYPI20070009A 2006-01-04 2007-01-04 Method for the production of methionine by culturing a microorganism modified to enhance production of cysteine MY148979A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/EP2006/050033 WO2007077041A1 (en) 2006-01-04 2006-01-04 Process for the preparation of methionine and its precursors homoserine or succinylhomoserine employing a microorganism with enhanced sulfate permease expression

Publications (1)

Publication Number Publication Date
MY148979A true MY148979A (en) 2013-06-28

Family

ID=37508334

Family Applications (1)

Application Number Title Priority Date Filing Date
MYPI20070009A MY148979A (en) 2006-01-04 2007-01-04 Method for the production of methionine by culturing a microorganism modified to enhance production of cysteine

Country Status (11)

Country Link
US (2) US8389250B2 (en)
EP (2) EP2314710B1 (en)
JP (1) JP5172697B2 (en)
CN (1) CN101351558B (en)
AR (1) AR058914A1 (en)
BR (1) BRPI0620880B1 (en)
DK (1) DK2314710T3 (en)
ES (1) ES2459617T3 (en)
MY (1) MY148979A (en)
PL (1) PL1969130T3 (en)
WO (1) WO2007077041A1 (en)

Families Citing this family (75)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP4110641B2 (en) 1998-11-17 2008-07-02 味の素株式会社 Method for producing L-methionine by fermentation
WO2007077041A1 (en) * 2006-01-04 2007-07-12 Metabolic Explorer Process for the preparation of methionine and its precursors homoserine or succinylhomoserine employing a microorganism with enhanced sulfate permease expression
EP2019868A2 (en) * 2006-05-24 2009-02-04 Evonik Degussa GmbH Process for the preparation of l-methionine
KR100905381B1 (en) 2006-07-28 2009-06-30 씨제이제일제당 (주) Microorganism producing l-methionine precursor and method of producing l-methionine and organic acid from the l-methionine precurosr
WO2009043372A1 (en) 2007-10-02 2009-04-09 Metabolic Explorer Increasing methionine yield
KR101241182B1 (en) 2008-03-19 2013-03-13 히라따기꼬오 가부시키가이샤 Work inspector and carrier
US9005952B2 (en) 2008-04-04 2015-04-14 Cj Cheiljedang Corporation Microorganism producing L-methionine precursor and the method of producing L-methionine precursor using the microorganism
US7851180B2 (en) * 2008-04-04 2010-12-14 Cj Cheiljedang Corporation Microorganism producing L-methionine precursor and the method of producing L-methionine precursor using the microorganism
WO2010022763A1 (en) * 2008-08-25 2010-03-04 Metabolic Explorer Method for the preparation of 2-hydroxy-isobutyrate
WO2010020290A1 (en) * 2008-08-22 2010-02-25 Metabolic Explorer Producing methionine without n-acetyl methionine
WO2010020289A1 (en) 2008-08-22 2010-02-25 Metabolic Explorer Production of n-acetylated sulphur-containing amino acids with microorganisms having enhanced n-acetyltransferase enzymatic activity
KR101827230B1 (en) 2008-12-31 2018-02-07 메타볼릭 익스플로러 Method for the preparation of diols
JP2012223092A (en) * 2009-08-28 2012-11-15 Ajinomoto Co Inc Method for producing l-amino acid
US8609396B2 (en) * 2009-08-28 2013-12-17 Cj Cheiljedang Corporation Microorganism producing O-acetyl-homoserine and the method of producing O-acetyl-homoserine using the microorganism
RU2009136544A (en) * 2009-10-05 2011-04-10 Закрытое акционерное общество "Научно-исследовательский институт "Аджиномото-Генетика" (ЗАО АГРИ) (RU) METHOD FOR PRODUCING L-CISTEINE USING THE ENTEROBACTERIACEAE FAMILY BACTERIA
FR2951195B1 (en) 2009-10-14 2014-01-31 Roquette Freres COMPOSITION RICH IN METHIONINE FOR ANIMAL FEEDING
JP5817529B2 (en) 2009-11-30 2015-11-18 味の素株式会社 L-cysteine producing bacterium and method for producing L-cysteine
WO2011073738A1 (en) 2009-12-14 2011-06-23 Metabolic Explorer Use of inducible promoters in the production of methionine
BR112012016274B1 (en) 2009-12-30 2019-08-20 Evonik Degussa Gmbh Increase in methionine production due to overexpression of dehydrogenase succinate
EP2519637A2 (en) * 2009-12-30 2012-11-07 Metabolic Explorer Strains and method for the production of methionine
WO2012001003A1 (en) 2010-07-02 2012-01-05 Metabolic Explorer Method for the preparation of hydroxy acids
TWI500768B (en) 2010-07-05 2015-09-21 Metabolic Explorer Sa Method for the preparation of 1,3-propanediol from sucrose
BR112013006031A2 (en) 2010-09-14 2016-06-07 Ajinomoto Kk bacteria, and method for producing a sulfur-containing amino acid, a related substance, or a mixture thereof.
KR101208267B1 (en) * 2010-10-20 2012-12-04 씨제이제일제당 (주) O-phosphoserine sulfhydrylase variants
AR083468A1 (en) 2010-10-25 2013-02-27 Metabolic Explorer Sa INCREASING NADPH'S AVAILABILITY FOR METIONIN PRODUCTION
WO2012090021A1 (en) 2010-12-30 2012-07-05 Metabolic Explorer Recombinant microorganism for the fermentative production of methionine
CN103429748B (en) * 2010-12-30 2016-01-06 代谢探索者公司 The fermentation of hydroxy analogue of methionine (MHA) produces
EP2479279A1 (en) 2011-01-20 2012-07-25 Evonik Degussa GmbH Method for producing sulphuric amino acids by means of fermentation
JP2014087259A (en) 2011-02-22 2014-05-15 Ajinomoto Co Inc L-cysteine-producing bacterium, and production method of l-cysteine
US9234223B2 (en) 2011-04-01 2016-01-12 Ajinomoto Co., Inc. Method for producing L-cysteine
WO2012137689A1 (en) 2011-04-01 2012-10-11 味の素株式会社 Method for producing l-cysteine
AR086790A1 (en) * 2011-06-29 2014-01-22 Metabolic Explorer Sa A MICROORGANISM FOR THE PRODUCTION OF METIONIN WITH IMPORTATION OF IMPROVED GLUCOSE
EP2540834A1 (en) 2011-06-29 2013-01-02 Metabolic Explorer Method for the preparation of 1,3-propanediol
US9410164B2 (en) 2011-10-11 2016-08-09 Metabolic Explorer Biosynthesis pathway for prenol in a recombinant microorganism
FR2983870B1 (en) 2011-12-08 2015-07-17 Roquette Freres METHIONINE COMPOSITION FOR ANIMAL FEEDING
EP2628792A1 (en) 2012-02-17 2013-08-21 Evonik Industries AG Cell with reduced ppGppase activity
EP2647718A3 (en) 2012-04-06 2014-12-24 Metabolic Explorer Process for producing 5-aminopentanoate empolying a recombinant microorganism
CN104411821B (en) 2012-06-18 2017-08-08 代谢探索者公司 Recombinant microorganism for fermenting and producing methionine
EP2700715B1 (en) 2012-08-20 2018-07-25 Evonik Degussa GmbH Method for manufacturing L-amino acids using improved strains of the enterobacteriaceae family by means of fermentation
WO2014049382A2 (en) 2012-09-26 2014-04-03 Metabolic Explorer Ethylenediamine fermentative production by a recombinant microorganism
WO2014071182A1 (en) 2012-11-01 2014-05-08 Massachusetts Institute Of Technology Directed evolution of synthetic gene cluster
PE20150681A1 (en) 2013-05-13 2015-05-15 Ajinomoto Kk METHOD TO PRODUCE L-AMINO ACIDS
PL3039153T3 (en) 2013-08-30 2019-02-28 Evonik Degussa Gmbh Microorganism for methionine production with improved methionine synthase activity and methionine efflux
JP6459962B2 (en) 2013-10-21 2019-01-30 味の素株式会社 Method for producing L-amino acid
JP6519476B2 (en) 2013-10-23 2019-05-29 味の素株式会社 Production method of target substance
JP6393898B2 (en) * 2014-08-03 2018-09-26 国立大学法人 奈良先端科学技術大学院大学 Yeast culture method
CA2959563A1 (en) 2014-09-01 2016-03-10 Metabolic Explorer Method and microorganism for methionine production by fermentation with improved methionine efflux
EP3050970B1 (en) 2015-01-28 2019-09-18 Metabolic Explorer Modified microorganism for optimized production of 1,4-butanediol
US10858675B2 (en) 2015-04-07 2020-12-08 Metabolic Explorer Modified microorganism for the optimized production of 2,4-dihydroxybutyrate with enhanced 2,4-dihydroxybutyrate efflux
EP3095868A1 (en) 2015-05-19 2016-11-23 Evonik Degussa GmbH Methionine production
EP3298156A1 (en) 2015-07-10 2018-03-28 Evonik Degussa GmbH Amino acid production
EP3322679A4 (en) 2015-07-13 2019-07-10 Pivot Bio, Inc. Methods and compositions for improving plant traits
US20180223319A1 (en) 2015-08-07 2018-08-09 Evonik Degussa Gmbh Protein thiocarboxylate-dependent l-methionine production by fermentation
WO2017042602A1 (en) 2015-09-10 2017-03-16 Metabolic Explorer New lactaldehyde reductases for the production of 1,2-propanediol
FR3041658B1 (en) 2015-09-30 2017-10-20 Arkema France PROCESS FOR PRODUCING L-METHIONINE
FR3041659B1 (en) 2015-09-30 2017-10-20 Arkema France PROCESS FOR PRODUCING L-METHIONINE
EP3359664A4 (en) 2015-10-05 2019-03-20 Massachusetts Institute Of Technology Nitrogen fixation using refactored nif clusters
CN108291243A (en) 2015-11-27 2018-07-17 赢创德固赛有限公司 The method for producing l-methionine
KR20180093981A (en) 2016-01-08 2018-08-22 에보니크 데구사 게엠베하 Method for producing L-methionine by fermentative production
EP3296404A1 (en) 2016-09-15 2018-03-21 Evonik Degussa GmbH Modified microorganism for production of methionine
CN110799474B (en) 2017-01-12 2022-07-26 皮沃特生物公司 Methods and compositions for improving plant traits
JP7066977B2 (en) 2017-04-03 2022-05-16 味の素株式会社 Manufacturing method of L-amino acid
BR112020000552A2 (en) 2017-07-11 2020-07-21 Adisseo France S.A.S. methionine-producing yeast
KR20200044015A (en) * 2017-08-09 2020-04-28 피벗 바이오, 인크. Methods and compositions for improving genetically engineered microorganisms
EP3470512A1 (en) 2017-10-10 2019-04-17 Metabolic Explorer Mutant phosphoserine aminotransferase for the conversion of homoserine into 4-hydroxy-2-ketobutyrate
CN111587287A (en) 2017-10-25 2020-08-25 皮沃特生物股份有限公司 Methods and compositions for improved nitrogen-fixing engineered microorganisms
CN112739668A (en) 2018-06-27 2021-04-30 皮沃特生物股份有限公司 Agricultural compositions comprising reconstituted nitrogen-fixing microorganisms
WO2020067487A1 (en) 2018-09-28 2020-04-02 Ajinomoto Co., Inc. Method for producing l-methionine using a bacterium
WO2020071538A1 (en) 2018-10-05 2020-04-09 Ajinomoto Co., Inc. Method for producing target substance by bacterial fermentation
WO2020198258A1 (en) * 2019-03-26 2020-10-01 Zymergen Inc. Engineered biosynthetic pathways for production of l-homocysteine by fermentation
KR102472559B1 (en) * 2019-06-28 2022-12-01 씨제이제일제당 주식회사 A method of producing sulfur-containing amino acids and derivatives thereof
KR102472558B1 (en) * 2019-06-28 2022-12-01 씨제이제일제당 주식회사 A method of producing sulfur-containing amino acids and derivatives thereof
CN113388630B (en) * 2020-03-11 2022-07-26 华东理工大学 Construction method and application of recombinant escherichia coli for synthesizing L-cysteine
CN112592924B (en) * 2020-12-28 2022-07-01 宁夏伊品生物科技股份有限公司 YH66_10325 gene-modified recombinant strain producing L-isoleucine as well as construction method and application thereof
CN114350586B (en) * 2022-01-24 2023-07-28 浙江工业大学 Genetically engineered bacterium for high-yield of L-cysteine, construction method and application

Family Cites Families (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2000157267A (en) 1998-11-24 2000-06-13 Ajinomoto Co Inc VARIATION TYPE metJ GENE AND PRODUCTION OF L-METHIONINE
US6831165B1 (en) * 1999-06-25 2004-12-14 Basf Aktiengesellschaft Corynebacterium glutamicum genes encoding proteins involved in homeostasis and adaptation
AU2223601A (en) * 1999-12-24 2001-07-09 Ajinomoto Co., Inc. Process for producing l-amino acid and novel gene
US7220571B2 (en) * 2000-09-28 2007-05-22 Archer-Daniels-Midland Company Escherichia coli strains which over-produce L-threonine and processes for the production of L-threonine by fermentation
ES2269712T3 (en) * 2001-07-11 2007-04-01 Degussa Gmbh PROCESS FOR THE PREPARATION OF L-AMINO ACIDS THAT USES ENVIRONMENTAL FAMILY STRAPS.
EP1686184B1 (en) 2001-07-11 2008-08-27 Evonik Degussa GmbH Process for the preparation of L-threonine using strains of the enterobacteriaceae family
US7160711B2 (en) * 2001-08-06 2007-01-09 Degussa Ag Coryneform bacteria which produce chemical compounds I
DE10239308A1 (en) * 2002-08-27 2004-03-11 Basf Ag Fermentative production of sulfur-containing fine chemicals, useful e.g. as feed additive, by culturing bacteria containing heterologous sequence for methionine synthase
CA2510475A1 (en) 2002-12-20 2004-07-08 Metanomics Gmbh & Co. Kgaa Method of producing amino acids in transgenic plants comprising expressing a nucleic acid encoding a threonine decomposing protein
DE10305774A1 (en) 2003-02-06 2004-08-26 Consortium für elektrochemische Industrie GmbH Process for the fermentative production of L-methionine
MXPA05008857A (en) 2003-02-18 2006-03-09 Metabolic Explorer Sa Method for the production of evolved microorganisms which permit the generation or modification of metabolic pathways.
WO2004108894A2 (en) 2003-05-30 2004-12-16 Microbia, Inc. Methods and compositions for amino acid production
RU2275425C2 (en) 2003-11-03 2006-04-27 Закрытое акционерное общество "Научно-исследовательский институт Аджиномото-Генетика" (ЗАО АГРИ) Bacterium belonging to genus escherichia as producer of l-cysteine and method for preparing l-cysteine
DE10359668A1 (en) 2003-12-18 2005-07-14 Basf Ag Process for the preparation of methionine
DE102004009454A1 (en) * 2004-02-27 2005-09-15 Degussa Ag Fermentative production of L-amino acids, especially methionine, useful e.g. in animal nutrition, by culturing bacteria in which components of the methionine uptake system are suppressed
DE102004013503A1 (en) 2004-03-18 2005-10-06 Degussa Ag Process for producing L-amino acids using coryneform bacteria
WO2005111202A1 (en) * 2004-05-12 2005-11-24 Metabolic Explorer Recombinant enzyme with altered feedback sensitivity
WO2006082254A2 (en) * 2005-02-07 2006-08-10 Metabolic Explorer Microorganisms comprising enzymes expressed with low gamma-elimination activity
JP2009501550A (en) * 2005-07-18 2009-01-22 ビーエーエスエフ ソシエタス・ヨーロピア Methionine-producing recombinant microorganism
WO2007077041A1 (en) * 2006-01-04 2007-07-12 Metabolic Explorer Process for the preparation of methionine and its precursors homoserine or succinylhomoserine employing a microorganism with enhanced sulfate permease expression

Also Published As

Publication number Publication date
AR058914A1 (en) 2008-03-05
JP5172697B2 (en) 2013-03-27
US20080311632A1 (en) 2008-12-18
EP1969130A1 (en) 2008-09-17
PL1969130T3 (en) 2014-08-29
JP2009521939A (en) 2009-06-11
EP2314710A3 (en) 2012-02-22
DK2314710T3 (en) 2016-06-13
EP1969130B1 (en) 2014-03-12
BRPI0620880B1 (en) 2018-10-09
EP2314710A2 (en) 2011-04-27
CN101351558A (en) 2009-01-21
CN101351558B (en) 2013-08-14
US20130183726A1 (en) 2013-07-18
BRPI0620880A2 (en) 2012-09-18
ES2459617T3 (en) 2014-05-12
US9187775B2 (en) 2015-11-17
US8389250B2 (en) 2013-03-05
WO2007077041A1 (en) 2007-07-12
EP2314710B1 (en) 2016-03-30

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