MY131426A - Hematopoietic arabinogalactan composition - Google Patents

Hematopoietic arabinogalactan composition

Info

Publication number
MY131426A
MY131426A MYPI20003006A MYPI20003006A MY131426A MY 131426 A MY131426 A MY 131426A MY PI20003006 A MYPI20003006 A MY PI20003006A MY PI20003006 A MYPI20003006 A MY PI20003006A MY 131426 A MY131426 A MY 131426A
Authority
MY
Malaysia
Prior art keywords
stimulating
exposure
arabinogalactan
compositions
csf
Prior art date
Application number
MYPI20003006A
Inventor
Jinhua An
Karen S Leu
Edwin S Lennox
John H Musser
Original Assignee
Pharmagenesis Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pharmagenesis Inc filed Critical Pharmagenesis Inc
Publication of MY131426A publication Critical patent/MY131426A/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08BPOLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B37/00Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
    • C08B37/006Heteroglycans, i.e. polysaccharides having more than one sugar residue in the main chain in either alternating or less regular sequence; Gellans; Succinoglycans; Arabinogalactans; Tragacanth or gum tragacanth or traganth from Astragalus; Gum Karaya from Sterculia urens; Gum Ghatti from Anogeissus latifolia; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/48Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae

Landscapes

  • Health & Medical Sciences (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Botany (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Biotechnology (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Medical Informatics (AREA)
  • Veterinary Medicine (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Materials Engineering (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Polymers & Plastics (AREA)
  • Organic Chemistry (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

PURIFIED ARABINOGALACTAN COMPOSITIONS ISOLATED FROM THE ROOTS OF ASTAGALUS MEMBRANACEUS, AND ARABINOGALACTAN PROTEIN COMPOSITIONS HAVING A WEIGHT AVERAGE MOLECULAR WEIGHT OF AT LEAST 100 KILODALTONS ISOLATED FROM THESE PURIFIED ARABINOGALACTAN COMPOSITIONS, ARE CAPABLE OF RECONSTITUTION INTO AQUEOUS INTRAVENOUSLY INJECTABLE FORMULATIONS; AND ARE USEFUL FOR STIMULATING HEMA TOPOIESIS, INDUCING THE PROLIFERATION OR MATURATION OF MEGAKARYOCYTES, STIMULATING THE PRODUCTION OF IL-Iβ, IL-6, TNF-α, IFN-У, GM-CSF, OR G-CSF, STIMULATING THE PRODUCTION OR ACTION OF NEUTROPHILS, TREATING NEUTROPENIA, ANEMIA, OR THROMBOCYTOPENIA, ACCELERATING RECOVERY FROM EXPOSURE (E.G. ACCIDENTAL OR NON-THERAPEUTIC EXPOSURE, ASWELL AS THERPEUTIC EXPOSURE) TO CYTOTOXIS AGENTS OR RADIATION, TREATING CACHEXIA, EMESIS, OR DRUG WITHDRAWAL SYSMTOMS, OR MODIFYING BIOLOGICAL RESPONSES OR PROTECTING HEPATIC CELLS IN HEPATITIS B, IN AMAMMAL WHEN INTRAVENOUSLY ADMINISTERED TO THE MAMMAL.
MYPI20003006A 1999-06-30 2000-06-30 Hematopoietic arabinogalactan composition MY131426A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US14203199P 1999-06-30 1999-06-30

Publications (1)

Publication Number Publication Date
MY131426A true MY131426A (en) 2007-08-30

Family

ID=22498290

Family Applications (1)

Application Number Title Priority Date Filing Date
MYPI20003006A MY131426A (en) 1999-06-30 2000-06-30 Hematopoietic arabinogalactan composition

Country Status (7)

Country Link
EP (1) EP1200482A1 (en)
CN (1) CN1179979C (en)
AU (1) AU6203600A (en)
HK (1) HK1046290B (en)
MY (1) MY131426A (en)
TW (1) TWI240629B (en)
WO (1) WO2001000682A1 (en)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2002002607A2 (en) * 2000-06-29 2002-01-10 Pharmagenesis, Inc. Acid-modified arabinogalactan protein composition
US7601368B2 (en) 2004-09-01 2009-10-13 Lupin Limited Purified Arabinogalactan-Protein (AGP) composition useful in the treatment psoriasis and other disorders
CN1854158B (en) * 2005-04-25 2011-09-07 蒋来高 Extraction of astragalus mongholicus polysaccharose by super-critical fluid technology
MY159317A (en) 2008-12-15 2016-12-30 Ecopharm Corp Treating idiopathic thrombocytopenic purpura with compositions comprising extracts of astragalus membranaceus
JP2017525702A (en) * 2014-08-18 2017-09-07 ファーマジェネシス, インコーポレイテッド Polygalacturonan rhamnogalacturonan (PGRG1) composition
CN104147254A (en) * 2014-08-21 2014-11-19 陈勇 Traditional Chinese medicine preparation for treating leucocytopenia after chemotherapy
CN109432242A (en) * 2018-11-07 2019-03-08 郑毅男 A kind of larch arabinogalactan preparation method and its application in terms of medical treatment
CN110551230B (en) * 2019-09-21 2022-02-15 天津赛诺制药有限公司 Preparation method of astragalus polysaccharide

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5589591A (en) * 1986-07-03 1996-12-31 Advanced Magnetics, Inc. Endotoxin-free polysaccharides
US4944946A (en) * 1987-01-27 1990-07-31 Yaguang Liu Pharmaceutical composition for inhibiting viruses and increasing immune function (PII)
CN1027168C (en) * 1989-05-13 1994-12-28 储大同 Bioregulator made from Inter leukin-2
IT1238685B (en) * 1990-02-09 1993-09-01 Indena Spa IMMUNOMODULATING ACTION POLYSACCHARIDES FROM ASTRAGALUS MEMBRANACEOUS AND PHARMACEUTICAL COMPOSITIONS THAT CONTAIN THEM
US5116969B1 (en) * 1990-04-26 1997-04-01 Larex International Inc Ultrarefined arabinogalactan product
ES2049561B1 (en) * 1991-04-27 1994-12-16 Andromaco Lab PROCEDURE FOR OBTAINING POLYMERS WITH ACTIVITY ON THE HEMATOPOYETIC SYSTEM.
US5770217A (en) * 1997-07-02 1998-06-23 Atlatl, Inc. Dietary supplement for hematological, immune and appetite enhancement

Also Published As

Publication number Publication date
HK1046290A1 (en) 2003-01-03
HK1046290B (en) 2005-08-12
WO2001000682A1 (en) 2001-01-04
TWI240629B (en) 2005-10-01
EP1200482A1 (en) 2002-05-02
AU6203600A (en) 2001-01-31
CN1368979A (en) 2002-09-11
CN1179979C (en) 2004-12-15

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