MY108145A - Process for preparing pyrrolidine carboxylic acid derivatives compositions - Google Patents

Process for preparing pyrrolidine carboxylic acid derivatives compositions

Info

Publication number
MY108145A
MY108145A MYPI92000323A MYPI19920323A MY108145A MY 108145 A MY108145 A MY 108145A MY PI92000323 A MYPI92000323 A MY PI92000323A MY PI19920323 A MYPI19920323 A MY PI19920323A MY 108145 A MY108145 A MY 108145A
Authority
MY
Malaysia
Prior art keywords
carboxylic acid
formula
pyrrolidine
acid derivatives
pyrrolidine carboxylic
Prior art date
Application number
MYPI92000323A
Inventor
Hyunglee Ae
Seung Lee Jae
Han Kim Ji
Hyun Baik Woo
Jin Kim Kyung
Original Assignee
Boryung Pharm
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boryung Pharm filed Critical Boryung Pharm
Publication of MY108145A publication Critical patent/MY108145A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/04—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/04—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D207/10—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D207/16—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pyrrole Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

THE PRESENT INVENTION RELATES TO A NOVEL PROCESS FOR PREPARING PYRROLIDINE CARBOXYLIC ACID DERIVATIVE OF THE FORMULA.(FORMULA 1) CHARACTERIZED BY REACTING THIOL GROUP-INTRODUCING AGENT OBTAINED FROM REACTION OF CARBON DISULFIDE AND ALKALI METAL HYDROXIDE IN AN AQUEOUS SOLUTION, WITH 1-[ 3-BROMO-(2S)- METHYL PROPIONYL] -PYRROLIDINE-(2S) -CARBOXYLIC ACID OF THE FORMULA.( FORMULA 2) AND THEN SUBJECTING THE RESULTING INTERMEDIATE COMPOUND TO ACID TREATMENT AND REDUCTION TREATMENT TO PROVIDE 1-[ 3-MERCAPTO-(2S) -METHYL PROPIONYL]- PYRROLIDINE-(2S)- CARBOXYLIC ACID (1).
MYPI92000323A 1991-11-07 1992-02-27 Process for preparing pyrrolidine carboxylic acid derivatives compositions MY108145A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
KR1019910019709A KR940005014B1 (en) 1991-11-07 1991-11-07 Process for producting pyrrolidine derivatives

Publications (1)

Publication Number Publication Date
MY108145A true MY108145A (en) 1996-08-30

Family

ID=19322380

Family Applications (1)

Application Number Title Priority Date Filing Date
MYPI92000323A MY108145A (en) 1991-11-07 1992-02-27 Process for preparing pyrrolidine carboxylic acid derivatives compositions

Country Status (6)

Country Link
KR (1) KR940005014B1 (en)
CN (1) CN1031752C (en)
GB (1) GB2262282B (en)
IT (1) IT1255497B (en)
MY (1) MY108145A (en)
PH (1) PH30239A (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103086940B (en) * 2011-10-28 2014-07-09 华中药业股份有限公司 Synthetic method of 1-(3-mercapto-2-D-methyl propionyl)-L-proline

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HU184082B (en) * 1979-12-29 1984-06-28 Egyt Gyogyszervegyeszeti Gyar Process for preparing 1-3-/3mercapto-/2s/-methyl-propinyl/-pyrrolidine-/2s/-carboxylic acid
JPS58124764A (en) * 1982-01-20 1983-07-25 Kanegafuchi Chem Ind Co Ltd Production of optically active thiol
KR870001570B1 (en) * 1984-12-19 1987-09-04 보령제약 주식회사 Preparing process for pyrolidine derivatives
KR870001569B1 (en) * 1985-02-11 1987-09-04 보령제약 주식회사 Preparing process for pyrolidine derivatives

Also Published As

Publication number Publication date
IT1255497B (en) 1995-11-09
CN1072175A (en) 1993-05-19
GB2262282B (en) 1995-08-23
PH30239A (en) 1997-02-05
GB2262282A (en) 1993-06-16
CN1031752C (en) 1996-05-08
KR940005014B1 (en) 1994-06-09
KR930009995A (en) 1993-06-21
GB9204428D0 (en) 1992-04-15
ITMI922157A1 (en) 1994-03-18
ITMI922157A0 (en) 1992-09-18

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