MY100956A - Controlled release potassium chloride. - Google Patents

Controlled release potassium chloride.

Info

Publication number
MY100956A
MY100956A MYPI87001249A MYPI19871249A MY100956A MY 100956 A MY100956 A MY 100956A MY PI87001249 A MYPI87001249 A MY PI87001249A MY PI19871249 A MYPI19871249 A MY PI19871249A MY 100956 A MY100956 A MY 100956A
Authority
MY
Malaysia
Prior art keywords
potassium chloride
controlled release
coated
micro pellets
aqueous environment
Prior art date
Application number
MYPI87001249A
Inventor
Ku Chou Chi-Tze
Hsiao Charles
Original Assignee
Key Pharma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from EP86901631A external-priority patent/EP0211946B1/en
Application filed by Key Pharma filed Critical Key Pharma
Publication of MY100956A publication Critical patent/MY100956A/en

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  • Medicinal Preparation (AREA)

Abstract

A CONTROLLED RELEASE POTASSIUM CHLORIDE TABLET WHICH IS COMPRISED OF POTASSIUM CHLORIDE CRYSTALS HAVING A MESH SIZE OF ABOUT 30 TO ABOUT 50 MESH WHICH ARE COATED WITH A COATING MATERIAL COMPRISED OF ETHYLCELLULOSE AND HYDROXYPROPYLCELLULOSE. THE COATED CRYSTALS FORM MICRO PELLETS WHICH THEN CAN BE COMPRESSED INTO TABLETS. THE TABLETS DISINTEGRATE RAPIDLY IN AN AQUEOUS ENVIRONMENT THUS ASSURING A MORE UNIFORM DISSOLUTION OF THE ACTIVE COMPONENT AS COMPARED WITH OTHER TYPES OF CONTROLLED RELEASE POTASSIUM CHORIDE DOSAGE FORMULATIONS. THE DISTRIBUTION OF THE POTASSIUM CHLORIDE MICRO PELLETS OVER A WIDE SURFACE AREA IN THE GASTROINTESTINAL MUCOSA AIDS IN REDUCING THE RISK OF GASTROINTESTINAL LESIONS. THE FORMATION OF THE COATED MICRO PELLETS WHICH DISPERSE QUICKLY UPON CONTACT WITH AQUEOUS ENVIRONMENT ALLOW FOR THE REPEATED CHRONIC ORAL ADMINISTRATION OF A RELATIVELY LARGE DOSE OF POTASSIUM CHLORIDE (20 MEQ).
MYPI87001249A 1985-02-19 1987-08-10 Controlled release potassium chloride. MY100956A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US70271485A 1985-02-19 1985-02-19
EP86901631A EP0211946B1 (en) 1985-02-19 1986-02-19 Controlled release potassium chloride

Publications (1)

Publication Number Publication Date
MY100956A true MY100956A (en) 1991-06-15

Family

ID=26106992

Family Applications (1)

Application Number Title Priority Date Filing Date
MYPI87001249A MY100956A (en) 1985-02-19 1987-08-10 Controlled release potassium chloride.

Country Status (2)

Country Link
AT (1) ATE52918T1 (en)
MY (1) MY100956A (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN115895664B (en) * 2022-12-28 2024-09-17 中国科学院西北生态环境资源研究院 Preparation method of biological skinning pellets for rapidly fixing sand in arid region

Also Published As

Publication number Publication date
ATE52918T1 (en) 1990-06-15

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