MY100148A - Process for preparing 1 , 5 - benzothiazepine derivatives - Google Patents

Process for preparing 1 , 5 - benzothiazepine derivatives

Info

Publication number
MY100148A
MY100148A MYPI88000710A MYPI19880710A MY100148A MY 100148 A MY100148 A MY 100148A MY PI88000710 A MYPI88000710 A MY PI88000710A MY PI19880710 A MYPI19880710 A MY PI19880710A MY 100148 A MY100148 A MY 100148A
Authority
MY
Malaysia
Prior art keywords
formula
compound
benzothiazepine derivatives
preparing
lower alkyl
Prior art date
Application number
MYPI88000710A
Inventor
Nobuyuki Futamaru
Hidefumi Kinoshita
Toshio Takahashi
Katsuhiko Kurabayashi
Susumu Nagao
Original Assignee
Tanabe Seiyaku Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from EP82106261A external-priority patent/EP0098892B1/en
Application filed by Tanabe Seiyaku Co filed Critical Tanabe Seiyaku Co
Publication of MY100148A publication Critical patent/MY100148A/en

Links

Landscapes

  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)

Abstract

A 1,5-BENZOTHIAZEPINE DERIVATIVES OF THE FORMULA : WHERE AR IS PHCNYL SUBSTITUTED WITH A LOWER ALKOXY, R IS A LOWER ALKYL, R1 AND R ARE EACH A LOWER ALKYL, AND Y IS A LOWER ALKYLENE IS PREPARED BY REACTING A 1,5- BENZOTHIAZEPIN DERATIVES OF THE FORMULA (II), PREFERABLY AN ALKALI METAL SALT THCREOF ON THE NITROGEN ATOM AT 5-POSITION, WITH A COMPOUND OF THE FORMULA (III) AS SHOWN IN THE FOLLOWING REACTION SCHEME-I.WHERE AR, R, R1, R2 AND Y ARE AS DEFINED ABOVE, AND Z IS A HALOGEN.THE COMPOUND (I) OF THE INVENTION HAS EXCELLENT CORONARY VASODILATING AND PSYCHONEUROTIC ACTIVITIES AND IS USEFUL PARTICULARLY AS A CA2+ -ANTIGONISTIC CORONARY VASODILATOR.
MYPI88000710A 1982-07-13 1988-06-27 Process for preparing 1 , 5 - benzothiazepine derivatives MY100148A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP82106261A EP0098892B1 (en) 1982-07-09 1982-07-13 Process for preparing 1,5-benzothiazepine derivatives

Publications (1)

Publication Number Publication Date
MY100148A true MY100148A (en) 1990-01-18

Family

ID=8189129

Family Applications (1)

Application Number Title Priority Date Filing Date
MYPI88000710A MY100148A (en) 1982-07-13 1988-06-27 Process for preparing 1 , 5 - benzothiazepine derivatives

Country Status (3)

Country Link
DE (1) DE3277532D1 (en)
HK (1) HK95588A (en)
MY (1) MY100148A (en)

Also Published As

Publication number Publication date
HK95588A (en) 1988-12-02
DE3277532D1 (en) 1987-12-03

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