MXPA06002374A - Blunt tip vial access cannula - Google Patents

Abstract

This present disclosure provides a non-coring vial access cannula which has sufficient structural strength that it may be made from a thermoplastic resin instead of metal, thus reducing the likelihood and severity of operator injury by an accidental needle stick. The vial access cannula of the present disclosure has (i) a needle hub suitable for receiving a hypodermic syringe or an IV set (e.g., a Luer lock), (ii) a cannula portion having a centrally disposed lumen, wherein the centrally disposed lumen terminatesin one or more distal openings and is in fluid communication with the needle hub, and (iii) a solid tip member distal to the one or more distal openings, wherein the solid tip member has a blade with a cutting edge.

Description

C ACCESS NULL FOR CLOSED PUNCTURE ROAD Field of the Invention This present disclosure relates to a useful cannula paxa penetrar_ membran s_.o_s.eptos __como s_e__üs.a commonly in medication vials, intravenous bags, access ports and the like. BACKGROUND OF THE INVENTION Many standard containers for pharmaceuticals, medicaments and other substances are air and moisture tight containers (eg, vials) that have elastomeric plugs. The contents of the container are commonly accessed by piercing the cap with a cannula needle apparatus such as a needle and common hypodermic syringe. In many applications, container contents are accessed repeatedly. For example, many injectable pharmaceuticals are packaged in multiple dose vials. that require a vial access for the withdrawal of each dose of unit. Also, many pharmacists are lyophilized in sterile vials for prolonged stability. Such packaging also requires multiple vial entries to reconstitute the contents and removal of the reconstituted contents. Commonly, elastomeric plugs are punched using a sharp metal channel needle; usually a needle Ref .: 170798 suitable for intravenous injection. A problem that arises with this type of access to the vial is that the center of the elastomeric stopper is removed. Removal from the center occurs as the vial access needle is pushed through the stopper and the needle stings or cuts a small particle of the tampon rubber. This plug fragment either falls into the vial or is lodged in the cannula and possibly withdraws into the syringe. In any case, the sterility of the contents of the container is compromised and, in the latter case, the injection of particulate matter into the patient may occur. The prior art discloses several access needles for vials for drug aspiration that include vial access needles that provide conically shaped forward tips and lateral ports that dispense fluids. See, for example, the MONOJECT® Filter Suction Needle (1973) manufactured by Sherwood Medical Industries Inc., and US Patent No. 4,058,121 to Choksi et al., Which describes access needles for vials for drug aspiration. Therefore, it would be desirable to overcome the disadvantages and drawbacks of the prior art with an access cannula for vials employing a structure that minimizes or eliminates the removal of the center from the elastomeric plugs. It may also be desirable that the vial access cannula be manufactured easily and efficiently.

Brief Description of the Invention Accordingly, a cannula useful for penetrating membranes or septums as commonly used in medication vials, intravenous bags, access ports and the like is provided having a closed point vial access cannula employing a structure for penetrating vials and the like to prevent removal of the center of the elastomeric stoppers to prevent the particles of the stopper from invading the pharmaceutical or the medicament to overcome the disadvantages and drawbacks of the prior art. Desirably, the closed tip vial access cannula includes a solid tip member structure which avoids removal of the center from the septum as was commonly used in medication vials, intravenous bags, access ports and the like. A particular embodiment of the present disclosure provides a cannula that does not remove the center to be used as a needle, for vial access. The cannula described here has sufficient structural hardness, which can be made of a thermoplastic resin instead of metal, thus reducing the likelihood and severity of operator damage by an accidental picketing of the needle. The vial access cannula of the present disclosure includes (i) a needle hub suitable for receiving a hypodermic syringe or an IV set, (ii) a cannula portion having a centrally disposed space, wherein the centrally disposed space terminates at one or more distal openings and is in fluid communication with the needle hub, and (iii) a solid tip member distant to one or more of the distant openings, wherein the solid tip member has a na? a_ja_con_Jina. ^ ermination. cut. In preferred embodiments, the centrally disposed space terminates in two distal openings and the distal openings are oriented such that the fluid flow is transverse to the axes of the centrally disposed space. Preferably, the knife is disposed at an angle α of about 5-45 ° of the vertical plane perpendicular to the longitudinal axes of the cannula, and more preferably, the knife is disposed at an angle of 10-20 °. In another illustrative embodiment, the solid tip member of the vial access cannula has one or more bevels such that the vertical length of the cutting termination is about 50-95% of the diameter of the cannula portion. The bevels that cause the reduction of the length of the cutting blade are arranged in an average way at an angle of about 5-25 ° C, and more preferably, about 8-15 °. In another embodiment, the vial access cannula has side faces that encompass the distal end of the cannula portion, a point proximate the lateral openings, and the proximal termination of the solid point member. In preferred embodiments, the distant boundary of the lateral face is the proximal termination of the bevel that forms the cutting end of the razor. In another embodiment, there is a laterally disposed bevel ad.i-C-i-on -1- between the distal face boundary, and the bevel that forms the cutoff. In one embodiment, the laterally disposed faces contain a medial groove which is arranged parallel to the longitudinal axis of the vial access cannula. Commonly, the middle grooves have substantially the same width as the openings distant from the. cannula centrally disposed and running distantly from the distal openings. At the distant termination, the middle slots end before the close boundary of the bevel that forms the cutoff. In particularly useful embodiments, the inner wall of the needle hub narrows which facilitates a type of Luer slip connection. In other embodiments, the needle hub contains a female portion of a Luer lock (that is, the Luer wings). Optionally, the hub of the needle, the flange, or the proximal end of the centrally disposed cannula may contain a filter. Useful filters include membrane filters (e.g., PVDF or methylcellulose), or microporous metal filters (e.g., stainless steel).

BRIEF DESCRIPTION OF THE DRAWINGS The foregoing and other features and advantages of the present disclosure will be more fully understood from the following detailed description of the e.g., e.g. FIGURE 1 is a perspective view of a cannula constructed in accordance with the principles of the present disclosure; FIGURE 2 is a perspective view of the cannula according to FIGURE 1; FIGURE 3 is a view of the plane of a distal portion of the cannula according to FIGURE 1; FIGURE 3A is a cross-sectional view of the distal portion of the cannula, through the plane 3A-3A, of FIGURE 3; FIGURE 4 is a cross-sectional side view of the cannula, through plane 4-4, of FIGURE 3; FIGURE 4A is a cross-sectional side view of partial call of an alternative embodiment of the cannula, through the plane 4-4, of FIGURE 3; FIGURE 5 is a view of the plane of the cannula according to FIGURE 1; FIGURE 6 is a view of the cross-sectional plane of the cannula, through plane 6-6, of FIGURE 5; FIGURE 7 is a view of the upper plane of the cannula of the present disclosure in accordance with FIGURE 1; and FIGURE 8 is a partial plane view of an alternative embodiment of the cannula according to the present disclosure. Detailed Description of the Exemplary Modalities The exemplary embodiments of the closed-tip vial access needle described herein are discussed in terms of cannulated needle devices for intravenous fluid infusion, medication infusion and fluid collection, and more particularly, in terms of manually accessing vials of pharmacists and the like housed in containers employing septum structures that require access such as medication vials, intravenous bags, access ports and the like. It is contemplated that the cannula may be protected during storage, transport, infusion and / or collection of fluid and thereafter. In the discussion that continues, the term "next" refers to a portion of a structure that is closer to a clinical staff, and the term "distant" refers to a portion that is further away from the clinical staff. As used herein, the term "subject" refers to a patient who receives infusions or has blood and / or fluids collected from him, when using the safety appliance. In accordance with the present disclosure, the term "clinical staff" refers to an individual who administers an infusion, who performs fluid collection, installation or removal of a needle cannula from a secure apparatus and may include support personnel. _____ ___._ Additionally, the term "cutting termination" refers to the union of one or more bevels and is located at the distant end of the cannula. The term "inclined razor" refers to a cutting termination, together with one or more bevels that form the cutting termination, in which the angle of the cutting termination is less than perpendicular to the longitudinal axis of the cannula to which is coupled. The following discussion includes a description of the closed tip vial access cannula, according to the present disclosure. Reference will now be made in detail to the exemplary embodiments of the description, which are illustrated in the accompanying figures. Returning now to the figures, where similar components are designated by similar numerical references in all the different views. Referring to FIGS. 1 and 2, the present disclosure provides an access cannula for vial without removal of center 10. Preferably, cannula 10 is molded of plastic into a unitary structure; however, it is contemplated that the cannula of the present disclosure can be fabricated from metal alloys. The cannula 10 includes a needle hub 12 in a proximal termination 14 thereof. The cannula 10 in this construction further includes a flange portion 13, which is arranged intermediate between. the hub portion of the needle 12 and a cannula portion 16. The cannula portion 16 includes a centrally disposed space 18 (shown in shadow), which ends in two distant openings 20. It is contemplated with the present disclosure that the cannula portion 16 may end in one or more distal openings 20. Cannula 10 terminates at its distal end 24 in a solid tip member 26. Solid tip member 26 is remote from distal openings 20 in the centrally disposed space 18.

The hub of the needle 12 is designed to receive a syringe or an IV assembly (not shown) and, in preferred embodiments, comprises the female portion of a Luer Lock 11. (that is, it has "rings" to fit the male threaded Luer connector). Preferably, the inner wall of the hub of the needle 12 tapers distally to provide a frictional fit with the received syringes or IV assemblies (ie, capable of functioning as a Luer slip connection). Other configurations of the needle hub 12 are possible and depend on each particular syringe or receiving device with which the cannula 10 of the present disclosure will be used.

The centrally disposed space 18 extends through the flange 13 and is in fluid communication with the hub of the needle 12 at the proximal termination 14. The centrally arranged space 18 terminates at one or more usable openings 20. In preferred embodiments, the Distant openings 20 are disposed laterally to the central longitudinal axis X of the cannula 10. In other preferred embodiments, the space 18 ends with two opposing distal openings 20, which are oriented at 90 ° C at the terminating termination cut. 32. Optionally, the needle hub 12 may include a filter within the centrally disposed space 18 or the inner portions of the flange 13 or the hub 12. Particularly useful filters include, for example, a microporous stainless steel filter. Suitable filters include, for example, membrane filters of 0.22 μm and 0.45 μm, and 5 μm random-pass membrane filters. The selection of the needle hub filter is left for the professional basis of each specific application. Generally, the manufacture and use of needle hub filters are well known in the art. During the operation, the flange portion 13 is designed to capture an upper portion of the elastomeric vial or plug in which the cannula 10 is to be inserted such that the flange 13 allows the depth of penetration of the cannula 10 through the stopper elastomeric There are no specific requirements for the shape of the flange 13, but in preferred embodiments, these contain one or more stop wings or members 15 symmetrically distributed around the circumference of the flange 13 y_. they extend out radially. Preferably, neither the flange 13 nor its wings 15 extend outwardly beyond the width of the needle hub 12. The solid tip member 26 contains an inclined blade 30 containing a cutting end 32 which is formed at the junction of the bevels 22. It is contemplated within the present description that the cutting end 32 is not perpendicular (ie, inclined) in relation to the longitudinal axis X of the cannula 10. The inclined blade 30, which includes the cutting termination 30 and the bevels 22, facilitate the penetration of elastomeric plugs and other vial closure devices. The solid tip member 26 further contains medial slots 28 which extend substantially from the distal openings 20 which run in a distal direction parallel to the centrally disposed space 18, but ending before the proximal termination of the bevels 22. The middle slots 28 they facilitate flow when the fluid is drained into the syringe (not shown) through the cannula 10.

The presence of medial grooves 28 aids the fabrication of the device in the mold by deflection of the ejected fluid stream within the angle, more preferably around 45 °, of the tip. The cannula 10 includes an additional face 38 which joins the distal end of the cannula portion 16 and the solid tip member 26. The faces 38 are commonly symmetrical on each of the side sides of the cannula 10 and are oriented parallel to the cutting termination 32. The purpose of the face 38 is to facilitate penetration of the solid tip member 26 and the cannula portion 16 of the cannula 10 through an elastomeric vial stopper. The cannula without the faces 38 generally requires the use of more force and are more prone to break the stopper of the vial. With reference to FIGURES 3 and 3A, the distal termination of the cannula portion 16 and a side view of the solid tip member 26 is shown. More specifically, the distal openings 20 are of equal widths, eg, about 0.025 mm, and substantially, are of the same width as the diameter as the centrally disposed space 18. The middle slots 28 preferably have substantially the same width as the distant openings 20. The solid tip member 26 has one or more upper bevels 36- along the first side 50 and one or more bottom bevels 37 along the second side 60. Although a pair of cutting bevels 22 and two pairs of side bevels 36 and 37 are shown, it is contemplated within the present disclosure that the solid point member 26 includes at least a cut bevel and at least one side bevel. The cutting termination 32 of the inclined blade 30 is disposed at an angle preferably of 5-45 °, more preferably 10-30 ° and more preferably around 10-20 °, to the vertical axis (ZZ) shown as perpendicular to the X-axis longitudinal of the cannula 10 (FIGURES 3 and 6). The bevels 36 and 37 effectively reduce the length of the cutting termination 32 and facilitate the penetration of the elastomeric vial plugs. Preferably, the bevels 36 and 37 reduce the length of the cutting end 32 by about 5-50% relative to the outer diameter of the cannula portion 16 by making the vertical length of the cutting end about 50-95% of the diameter of the cannula portion 16. The bevels 36 and 37 can be formed as a smooth arch or by two, three, four or more bevels • and still perform substantially the same function. FIGURE 3A shows a cross section, through the plane 3A-3A, of the solid tip member 26 having bevels 36 on the first side 50 and bevels 37 on the second side 60. In this embodiment, each of the bevels 36 and 37 are dissected by forming bevels, each at a bevel angle ß to the Y axis. While it is preferred that each bevel in a pair of bevels have the same angle ß, whose angles may be different from one another. In preferred embodiments for which the bevels 36 and 37 have two bevels, the bevel angle ß is preferably about 15-30 °, more preferably about 17-27 ° and more preferably about 22-24 °.

Although it is preferable, for a cannula 10 having 36 and 37 symmetrical bevels in cross section (FIGURE 3A), symmetry is not required. For example, the first side 50 the bevels 36 may have a rounded profile, while on the second side 60 the bevels 37 have a beveled profile. As shown in more detail in FIGURE 6, bevels 36 and 37 are arranged mid-way at an angle? and y ', respectively, of preferably about 5-25 °, more preferably 7-20 ° and more preferably about 8-15 ° of the X-axis. It is contemplated within the present description that the angles Y and Y' may be The purpose of the bevels 36 and 37 is to reduce the length of the cutting end 32, thereby reducing the force required to press the cannula 10 through a elastomeric stopper. The reduction in length of the cutting termination 32 is a function of the bevel angle α, the length along the longitudinal X axis, of the solid tip member 26, and the precise point of origin of the bevels 36 and 37 in its next termination. Returning now to FIGURE 4, a preferred embodiment of the distal termination of the cannula portion 16 and the solid tip member 26 is shown in a cross sectional top view of plane 4-4 of FIGURE 3. The cutting completion 32 is formed at the juncture of the bevels 22. The bevels 22 each form an angle d of preferably about 20-30 °, more preferably about 25-35 ° and more preferably about 28-32 ° with the X-axis longitudinal of the cannula 10. In a preferred embodiment, the bevels 22 each form an angle of about 30 ° with the longitudinal axis X of the cannula 10, which results in the cutting termination 32 having a total interior angle of about of 60 °. The preferred width A of the inclined blade 30 is about 1.47 mm with each bevel 22 forming an angle d of about 30 ° with the longitudinal X axis. With reference to FIGURE 4A, there is described a side view of partial cross section (through plane 4-4 of FIGURE 3) of a modality _5. Alternatively, the cannula portion 16. The centrally disposed cannula portion space 16 includes a distally located termination wall portion 27. The wall portion 27 can be formed in a variety of ways including For example, an arc shape (FIGURE 3), plurality of frustoconical shapes (FIGURE 4) or unique frustoconical shape (FIGURE 4A). The shape of the wall portion 27 is formed by a terminal termination of a core fastener (not shown) used in the manufacture of the cannula 10. During the manufacture of the cannula 10, a metal core fastener having, for example, a single reverse frusto-conical shape or reverse wedge shape, is used to form the wall portion 27 how I know shows in FIGURE 4A. The shape of the wall portion 27 can be used to control or reverse the flow of fluid through the distal openings 20. For example, the supply of fluid through the distal openings 20 is best provided (ie, in a forward dew direction) less than ninety degrees (90 °), and preferably less than forty-five (45 °) of the longitudinal X axis of the cannula 10. Refer now to FIGS. 7, there is described an alternate view of the cannula according to the present description. These figures are described in terms of a preferred embodiment which is useful for many medical applications. Of course, the exact dimensions can be altered, within the scope of the description, depending on each particular application for which a vial access cannula 10 is required. FIGURE 5 shows the preferred embodiment of the complete cannula 10 in top view . The overall length B of the cannula 10 is about 1128 cm. The length C of the cube of agu to 12 is around 0.308 cm which, together with the flange portion 13, is about 0.595 cm in length D. The length E (FIGURE 6) of the portion of the cannula 16 is about 0.386 cm (from the distant termination of the portion of the flange 13 to the distal termination of the space 18), which together with the solid tip member 26 comprises a length F of about 0.533 cm. To facilitate the penetration of the cannula 10 through an elastomeric plug, optionally, the proximal region of the cannula portion 16 is narrowed by the formation of an angle? L with the X axis. Preferably, the angle? L is about 2-6 ° and more preferably around 4 °. He The narrowing of the proximal region of the cannula portion 16 preferably reduces the outer diameter from about 0.106 cm at the junction with the flange portion 13 to about 0.088 cm at the distant end G. The space provided centrally 18 can be narrowed, either continuously or discontinuously, over the length of the cannula portion 16. Preferably, the centrally disposed space 18 has a diameter H of about 0.033 cm in the remote openings 20 and around 0.050 cm at its junction with the flange portion 13. The centrally disposed space 18 preferably tapers at the flange portion 13. As discussed above, in preferred embodiments, the solid tip member 26 has a At least one bevel 36 on the first side 50 and at least one bevel 37 on the second side 60. More preferably, each angle Y and Y 'of the bevel is about 8-15 °. In this preferred embodiment, which has - both bevels 36 and 37 in about one angle? yY of 11 °, the vertical length of the cutting end 32 is about 0.058 cm which represents a reduction of about 0.030 cm compared to the diameter G of the cannula portion 16. The reduction of 0.030 cm in length __5 vertical I is comprised of around a reduction of 0. 015 cm both on the first side 50 and on the second side 60. As discussed above, preferably, the needle hub 12 engages with the male portion of a connector Luer threaded and / or works as a Luer slip connector. The appropriate dimensions for these types of connectors are well known in the art. For example, the depth C of the syringe receiving portion of the needle hub 12 is about 0.305 cm and is flared about about 0.25 cm proximal of the depth J. In an appropriate flared configuration, the needle hub 12 has a luminal diameter K of about 0.155 cm across the distant termination and a diameter 0 Luminar L of about 0.210 cm towards the next opening. The outer diameter of the needle hub, which excludes the rings of Luer 11, is about 0.234 cm. In another preferred embodiment, the inner corner of the proximal opening of the needle hub 12 is bevelled at an angle T2, which facilitates the entry of the syringe end into the needle hub 12. Suitably, T2 may be about of 30-55 °, but preferably it is around 45 °. With reference to FIGURE 7, a view of the lower plane of one embodiment of the cannula 10 is shown. In this embodiment, the needle hub 12 contains a Luer lock 11 which is oriented parallel to the cutting termination 32 (axis Z) The flange portion 13 contains four flange flanges 15, which are offset by 45 ° relative to the plane of the cutting end 32 (the Z axis). The flange wings 15 can, of course, be rotated at any convenient angle or they can adopt different configurations if a number of flange flanges 15 other than four is used. The cannula portion 16 terminates in two laterally disposed remote openings 20. The solid tip member 26 has two bevels 36, two middle slots 28 and symmetrical side faces 38. With reference to FIGURE 8, an alternative cannula 10 'includes a cannula portion 16 'and solid tip member 26' having a first side 29. The cannula 10 'includes a space 18' (shown in shadow) ending in wall portion 27 'd.e ... a. 20 'distant opening. The solid tip member 26 'includes at least one cutting bevel and at least one side bevel. More specifically, the solid tip member 26 'includes one or more upper bevels 36' along the length of the e_r_la_d or 50_ _ _ y. n o ___o more bis e_l_es_ .i nferiores 37 'along the second side 60'. The bevels 36 'and 37' may be of certain lengths to effectively reduce the length of the cutting ends 32 ', which facilitates the penetration of elastomeric vial plugs. Although the multiple 32 'cut ends are shown, it is contemplated that one or more cut ends 32' may be incorporated with the solid tip member 26 '. The bevels 36 'and 37' can be formed as smooth arcs having curved or flat planes or flat or curved cut ends, or by two or more bevels. The cannula portion 16'- can include a second opposite side 31 formed as a mirror image of the first side side 29. Alternatively, the second opposite side 31 can be formed as a flat surface having a plane substantially parallel to the X axis longitudinal of the cannula 10 '. Although the foregoing description has been described in some detail by way of illustration and example for purposes of clarity of understanding, it will be readily apparent to those of ordinary skill in the art in light of the teachings of this present disclosure that certain changes and modifications they can be done to it without departing from the spirit or scope of the appended claims. It is noted that in relation to this date, the best method known by the applicant to carry out the aforementioned invention, is the conventional one for the manufacture of the objects to which it relates.

Claims (23)

1. CLAIMS Having described the invention as above, the content of the following claims is claimed as property. "5, ..... 1. An access cannula for a vial characterized in that it comprises: a needle hub; a portion of the cannula connected to the needle hub and

   10 having a centrally disposed space, wherein the centrally located remote space ends in at least one aperture disposed and is in fluid communication with the needle hub; and a solid tip member disposed distant from

   15 at least one distal opening, wherein the solid tip member includes at least one blade having at least one beveled face extending to a cutting end.
2. 2. The vial access cannula in accordance with claim 1, characterized in that at least one blade includes opposite beveled faces extending to the cutting termination.
3. 3. The vial access cannula according to claim 1, characterized in that the

   The solid tip member includes at least two beveled faces extending to at least two cutting endings.
4. 4. The vial access cannula according to claim 1, characterized in that the centrally arranged space terminates in two distant openings and the fluid flow through the distal openings is transverse to the axis of the centrally disposed space.
5. 5. The vial access cannula according to claim 1, characterized in that the cannula further comprises at least one side face that encompasses a region remote from the cannula portion and a proximal region of the solid tip member.
6. 6. The vial access cannula according to claim 1, characterized in that each of the laterally disposed faces further comprises a middle slot, wherein the middle slot (i) is arranged parallel to the longitudinal axis of the cannula, (ii) ). it has substantially the same width as the distant openings, and (iii) runs distantly from the distant openings and ends close to at least one knife.
7. 7. The vial access cannula according to claim 1, characterized in that at least one knife is disposed at an angle of about 5-45 ° from a vertical plane perpendicular to a longitudinal axis of the cannula.
8. 8. The vial access cannula according to claim 1, characterized in that the cutting termination of at least one beveled face has a vertical length of about 50-95% of the diameter of the cannula portion.
9. 9. The vial access cannula according to claim 8, characterized in that each of at least one beveled face is disposed at an average angle of about 5-25 °.
10. 10. The vial access cannula according to claim 1, characterized in that the needle hub comprises the female portion of a Luer latch.
11. 11. The vial access cannula according to claim 1, characterized in that the needle hub further comprises a filter.
12. 12. The vial access cannula according to claim 1, characterized in that the vial access cannula is molded.
13. 13. A vial access cannula characterized in that it comprises: a needle hub, wherein the needle hub includes the female portion of a Luer lock; a cannula portion connected to the needle hub YL__gue has _. a centrally disposed space, wherein the arranged space, centrally ends in two distant openings arranged laterally and is in fluid communication with the needle hub; and a solid tip member remote from the distal openings, wherein the solid tip member comprises at least one blade, the at least one blade has at least one beveled face extending to a cutting end disposed in a angle of about 5-45 ° from an axis perpendicular to a longitudinal axis of the cannula, and wherein the vertical length of the cutting termination is about 50-95% of the diameter of the cannula portion.
14. 14. The vial access cannula according to claim 13, characterized in that the at least one blade includes opposite beveled faces extending to the cutting termination.
15. 15. The vial access cannula according to claim 13, characterized in that the solid tip member includes at least two bevelled faces extending to at least two cutting ends.
16. 16. The vial access cannula according to claim 13, characterized in that it further comprises at least one lateral face that encompasses a region remote from the cannula portion and a proximal region of the solid tip member.
17. 17. The vial access cannula according to claim 16, characterized in that each of the laterally disposed faces further comprises a middle slot, wherein the middle slot

    (i) is disposed parallel to the longitudinal axis of the cannula, (ii) has substantially the same width as the distal openings, and (iii) runs distally from the distal openings and ends close to at least one blade.
18. 18. The vial access cannula according to claim 13, characterized in that the cutting termination includes two beveled faces arranged at an angle of about 20-40 ° from the longitudinal axis of the cannula.
19. 19. The vial access cannula according to claim 13, characterized in that the vial access cannula is molded of plastic.
20. 20. An access cannula for molded plastic vial characterized in that it comprises: (i) a needle hub suitable for receiving a
21. _5_ j_erin_ga hipodé tnica_oor a set IV, where the needle hub comprises the female portion of a Luer lock; (ii) a cannula portion connected to the needle hub and having a centrally disposed space, wherein the centrally disposed space terminates in two laterally disposed distant openings and is in fluid communication with the needle hub; (iii) a solid tip member remote from the distal openings, wherein the solid tip member comprises (a) two bevels, wherein the two bevels are arranged medially at an angle of about 5-25 °, and (b) at least one blade, the at least one blade has at least one beveled face extending to a cutting end disposed at an angle of about 5-45 ° of an axis perpendicular to a longitudinal axis of the cannula, wherein the vertical length of the cutting termination is about 50-95% of the diameter 25 of the cannula portion, and the cutting termination forms an angle of 60 °; and (iv) two laterally disposed faces, wherein the faces extend to a region remote from the cannula portion and a proximal region of the solid tip member. 2_l _.__ The vial access cannula according to claim 20, characterized in that at least one blade includes opposite beveled faces extending to the cutting termination.
22. 22. The vial access cannula according to claim 20, characterized in that the solid tip member includes at least two bevelled faces extending to at least two cut ends.
23. 23. The vial access cannula according to claim 20, characterized in that each of the laterally disposed faces further comprises a middle slot, wherein the middle slot (i) is arranged parallel to the longitudinal axis of the cannula, (ii) has substantially the same width as the distant openings, and (iii) runs distantly from the distant openings and ends close to at least one knife.