MXPA05007793A - Composiciones de nucleotidos enlazados con alquilo. - Google Patents
Composiciones de nucleotidos enlazados con alquilo.Info
- Publication number
- MXPA05007793A MXPA05007793A MXPA05007793A MXPA05007793A MXPA05007793A MX PA05007793 A MXPA05007793 A MX PA05007793A MX PA05007793 A MXPA05007793 A MX PA05007793A MX PA05007793 A MXPA05007793 A MX PA05007793A MX PA05007793 A MXPA05007793 A MX PA05007793A
- Authority
- MX
- Mexico
- Prior art keywords
- alkyl
- linked nucleotide
- nucleotide
- nucleotide compositions
- methods
- Prior art date
Links
Classifications
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
- B01D15/08—Selective adsorption, e.g. chromatography
- B01D15/26—Selective adsorption, e.g. chromatography characterised by the separation mechanism
- B01D15/38—Selective adsorption, e.g. chromatography characterised by the separation mechanism involving specific interaction not covered by one or more of groups B01D15/265 - B01D15/36
- B01D15/3804—Affinity chromatography
- B01D15/3819—Affinity chromatography of the nucleic acid-nucleic acid binding protein type
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
- B01J20/281—Sorbents specially adapted for preparative, analytical or investigative chromatography
- B01J20/286—Phases chemically bonded to a substrate, e.g. to silica or to polymers
- B01J20/289—Phases chemically bonded to a substrate, e.g. to silica or to polymers bonded via a spacer
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H21/00—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids
- C07H21/04—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids with deoxyribosyl as saccharide radical
Landscapes
- Chemical & Material Sciences (AREA)
- Analytical Chemistry (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Biotechnology (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Saccharide Compounds (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Solid-Sorbent Or Filter-Aiding Compositions (AREA)
Abstract
Se proporcionan composiciones de nucleotidos enlazados con alquilo y medios con afinidad a nucleotidos que comprenden un nucleotido enlazado con alquilo. El enlazador es generalmente un enlazador hidrofobico que puede ser una cadena de carbonos 3, 4, 5, 6, 7, 8, 9, 10 o mas larga. Tambien estan incluidos en la invencion metodos para la sintesis de un nucleotido enlazado con alquilo, medios con afinidad a nucleotidos y metodos para el uso de los mismos para cromatografia por afinidad y metodos de deteccion.
Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US45369703P | 2003-01-22 | 2003-01-22 | |
US53213403P | 2003-12-23 | 2003-12-23 | |
US10/762,078 US7371852B2 (en) | 2003-01-22 | 2004-01-21 | Alkyl-linked nucleotide compositions |
PCT/US2004/001745 WO2004065566A2 (en) | 2003-01-22 | 2004-01-22 | Alkyl-linked nucleotide compositions |
Publications (1)
Publication Number | Publication Date |
---|---|
MXPA05007793A true MXPA05007793A (es) | 2006-01-31 |
Family
ID=32777037
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MXPA05007793A MXPA05007793A (es) | 2003-01-22 | 2004-01-22 | Composiciones de nucleotidos enlazados con alquilo. |
Country Status (7)
Country | Link |
---|---|
US (1) | US7371852B2 (es) |
EP (1) | EP1585754A2 (es) |
JP (1) | JP2007524804A (es) |
AU (1) | AU2004205922A1 (es) |
CA (1) | CA2513901A1 (es) |
MX (1) | MXPA05007793A (es) |
WO (1) | WO2004065566A2 (es) |
Families Citing this family (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US8802448B2 (en) * | 2011-07-27 | 2014-08-12 | Pall Corporation | Mixed mode ligands |
US9828599B2 (en) | 2013-09-18 | 2017-11-28 | General Electric Company | Methods of selecting binding-elements and uses thereof |
US20150093839A1 (en) | 2013-10-02 | 2015-04-02 | General Electric Company | Methods and systems for detection of target and applications thereof |
US10359419B2 (en) | 2013-10-02 | 2019-07-23 | General Electric Company | Methods for detection of target using affinity binding |
Family Cites Families (18)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4529796A (en) | 1981-03-30 | 1985-07-16 | Baker Instruments Corporation | Method for making chromogenic and/or fluorogenic substrates for use in monitoring catalytic or enzymatic activity |
AU613592B2 (en) | 1986-11-18 | 1991-08-08 | Institute Of Organic Chemistry And Biochemistry Of The Academy Of Sciences Of The Czech Republic | Antiviral phosophonomethoxy-alkyene purine and pyrimide derivatives |
US5650510A (en) | 1986-11-18 | 1997-07-22 | Institute Of Organic Chemistry And Biochemistry Of The Academy Of Sciences Of The Czech Republic | Antiviral phosphonomethoxyalkylene purine and pyrimidine derivatives |
EP0338887B1 (en) | 1988-04-19 | 1993-12-08 | Merrell Dow Pharmaceuticals Inc. | Phosphonoalkylpurine derivatives |
EP0338168A1 (en) | 1988-04-19 | 1989-10-25 | Merrell Dow Pharmaceuticals Inc. | Phosphonoalkylpurine derivatives |
JPH04503408A (ja) * | 1989-02-21 | 1992-06-18 | イーストマン コダック カンパニー | 非多孔質単分散ポリマー充填物質を含む高速アフィニティクロマトグラフカラム |
CA2083961A1 (en) | 1990-05-29 | 1991-11-30 | Henk Van Den Bosch | Synthesis of glycerol di- and triphosphate derivatives |
JPH0490850A (ja) * | 1990-08-02 | 1992-03-24 | Toray Ind Inc | 表面を化学的に活性化した微多孔性支持体 |
US5536822A (en) | 1994-03-09 | 1996-07-16 | University Of Virginia Alumni Patents Foundation | γ-phosphate linked adenosine 5' triphosphate sepharose |
US5728369A (en) * | 1994-10-05 | 1998-03-17 | Immunomedics, Inc. | Radioactive phosphorus labeling of proteins for targeted radiotherapy |
US5981507A (en) * | 1995-12-14 | 1999-11-09 | Advanced Magnetics, Inc. | Polymeric carriers linked to nucleotide analogues via a phosphoramide bond |
WO1998000435A2 (en) * | 1996-07-03 | 1998-01-08 | President And Fellows Of Harvard College | Oligonucleotide linker and techniques involving immobilized and linked oligonucleotides |
CA2369868A1 (en) * | 1999-04-15 | 2000-10-26 | The University Of Virginia Patent Foundation | Proteome mining |
ATE414171T1 (de) * | 1999-08-27 | 2008-11-15 | Matrix Technologies Corp | Verfahren zur immobilisierung von oligonukleotiden auf festem trägermaterial |
DE10019136A1 (de) * | 2000-04-18 | 2001-10-31 | Aventis Pharma Gmbh | Polyamidnukleinsäure-Derivate, Mittel und Verfahren zu ihrer Herstellung |
US6623655B1 (en) * | 2000-04-24 | 2003-09-23 | Sigma-Aldrich Co. | Metal chelating compositions |
US20030027140A1 (en) * | 2001-03-30 | 2003-02-06 | Jingyue Ju | High-fidelity DNA sequencing using solid phase capturable dideoxynucleotides and mass spectrometry |
US7323319B2 (en) * | 2003-05-29 | 2008-01-29 | The University Of Southern Mississippi | RNA containing coenzymes, biotin, or fluorophores, and methods for their preparation and use |
-
2004
- 2004-01-21 US US10/762,078 patent/US7371852B2/en not_active Expired - Fee Related
- 2004-01-22 CA CA002513901A patent/CA2513901A1/en not_active Abandoned
- 2004-01-22 WO PCT/US2004/001745 patent/WO2004065566A2/en active Application Filing
- 2004-01-22 JP JP2006501102A patent/JP2007524804A/ja active Pending
- 2004-01-22 MX MXPA05007793A patent/MXPA05007793A/es unknown
- 2004-01-22 AU AU2004205922A patent/AU2004205922A1/en not_active Abandoned
- 2004-01-22 EP EP04704469A patent/EP1585754A2/en not_active Withdrawn
Also Published As
Publication number | Publication date |
---|---|
JP2007524804A (ja) | 2007-08-30 |
WO2004065566A3 (en) | 2004-11-18 |
WO2004065566A2 (en) | 2004-08-05 |
AU2004205922A1 (en) | 2004-08-05 |
CA2513901A1 (en) | 2004-08-05 |
US7371852B2 (en) | 2008-05-13 |
US20040215009A1 (en) | 2004-10-28 |
EP1585754A2 (en) | 2005-10-19 |
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