MXPA05004917A - Combinacion que comprende docetaxel y un inhibidor cdk. - Google Patents

Combinacion que comprende docetaxel y un inhibidor cdk.

Info

Publication number
MXPA05004917A
MXPA05004917A MXPA05004917A MXPA05004917A MXPA05004917A MX PA05004917 A MXPA05004917 A MX PA05004917A MX PA05004917 A MXPA05004917 A MX PA05004917A MX PA05004917 A MXPA05004917 A MX PA05004917A MX PA05004917 A MXPA05004917 A MX PA05004917A
Authority
MX
Mexico
Prior art keywords
docetaxel
cdk inhibitor
combination
prodrug
derivative
Prior art date
Application number
MXPA05004917A
Other languages
English (en)
Inventor
Giannella-Borradori Athos
Original Assignee
Cyclacel Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GBGB0225872.1A external-priority patent/GB0225872D0/en
Priority claimed from GB0318813A external-priority patent/GB0318813D0/en
Application filed by Cyclacel Ltd filed Critical Cyclacel Ltd
Publication of MXPA05004917A publication Critical patent/MXPA05004917A/es

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/335Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/337Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having four-membered rings, e.g. taxol
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • A61K31/52Purines, e.g. adenine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02ATECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Transition And Organic Metals Composition Catalysts For Addition Polymerization (AREA)

Abstract

Un primer aspecto de la presente invencion se refiere a una combinacion que comprende docetaxel o un derivado o profarmaco del mismo, y un inhibidor CDK. Un segundo aspecto de la presente invencion se refiere a un producto farmaceutico que comprende docetaxel o un derivado o profarmaco del mismo y un inhibidor CDK en la forma de una preparacion combinada para utilizarse en terapias en forma simultanea, en secuencias o por separado. Un tercer aspecto de la presente invencion se refiere a un metodo para tratar un padecimiento proliferativo, en donde el metodo comprende administrar un sujeto en forma simultanea, en secuencias o por separado docetaxel, o un derivado o profarmaco del mismo y un inhibidor CDK.
MXPA05004917A 2002-11-06 2003-11-05 Combinacion que comprende docetaxel y un inhibidor cdk. MXPA05004917A (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GBGB0225872.1A GB0225872D0 (en) 2002-11-06 2002-11-06 Combination
GB0318813A GB0318813D0 (en) 2003-08-11 2003-08-11 Combination
PCT/GB2003/004780 WO2004041268A1 (en) 2002-11-06 2003-11-05 Combination comprising docetaxel and a cdk inhibitor

Publications (1)

Publication Number Publication Date
MXPA05004917A true MXPA05004917A (es) 2005-08-18

Family

ID=32313983

Family Applications (1)

Application Number Title Priority Date Filing Date
MXPA05004917A MXPA05004917A (es) 2002-11-06 2003-11-05 Combinacion que comprende docetaxel y un inhibidor cdk.

Country Status (11)

Country Link
US (1) US20050277656A1 (es)
EP (1) EP1558242B1 (es)
JP (1) JP4764165B2 (es)
AT (1) ATE418333T1 (es)
AU (1) AU2003276467A1 (es)
BR (1) BR0316010A (es)
CA (1) CA2502973A1 (es)
DE (1) DE60325502D1 (es)
ES (1) ES2318202T3 (es)
MX (1) MXPA05004917A (es)
WO (1) WO2004041268A1 (es)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0012528D0 (en) * 2000-05-23 2000-07-12 Univ Palackeho Triterpenoid derivatives
US20070287718A1 (en) * 2003-11-06 2007-12-13 Green Simon R Methods for the Treatment of Multiple Myeloma Using Roscovitine
ES2390237T3 (es) * 2006-02-10 2012-11-07 Nerviano Medical Sciences S.R.L. Combinaciones que comprenden un inhibidor de cdk y un anticuerpo anti-factor de crecimiento o un agente antimitótico
ES2500465T3 (es) * 2006-10-06 2014-09-30 Bavarian Nordic Inc. Virus vaccinia Ankara modificado recombinante que codifica antígeno HER-2 en combinación con un taxano para uso en el tratamiento del cáncer
EP2178531A4 (en) * 2007-07-02 2012-01-11 Yu Ming METHODS AND COMPOSITIONS, TARGETS FOR COMBINED CANCER TREATMENTS
JP6286421B2 (ja) 2012-05-15 2018-02-28 サイクラセル リミテッド サパシタビン及びセリシクリブの投与レジメン

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2741881B1 (fr) * 1995-12-01 1999-07-30 Centre Nat Rech Scient Nouveaux derives de purine possedant notamment des prorietes anti-proliferatives et leurs applications biologiques
US6235776B1 (en) * 1998-11-12 2001-05-22 Cell Pathways, Inc. Method for treating a patient with neoplasia by treatment with a paclitaxel derivative
GB9904932D0 (en) * 1999-03-04 1999-04-28 Glaxo Group Ltd Composition and method for preventing/reducing the severity of side effects of chemotherapy and/or radiation therapy
AU2002228849A1 (en) * 2000-12-08 2002-06-18 Bristol-Myers Squibb Pharma Company Semicarbazides and their uses as cyclin dependent kinase inhibitors
UY27220A1 (es) * 2001-03-23 2002-09-30 Aventis Pharma Sa Combinación de un taxano con una quinasa ciclina-dependiente
US6949558B2 (en) * 2001-11-07 2005-09-27 Yale University Enhancement of taxane-based chemotherapy by a CDK1 antagonist
EP1485168A1 (en) * 2002-03-15 2004-12-15 Cyclacel Limited Combination of a cdk inhibitor and 5-fu for the treatment of cancer
AU2003276463A1 (en) * 2002-11-06 2004-06-07 Cyclacel Limited Combination comprising a cdk inhibitor and cisplatin
EP1558289A1 (en) * 2002-11-06 2005-08-03 Cyclacel Limited Pharmaceutical composition comprising a cdk inhibitor and gemcitabine
GB0225873D0 (en) * 2002-11-06 2002-12-11 Cyclacel Ltd Combination

Also Published As

Publication number Publication date
US20050277656A1 (en) 2005-12-15
EP1558242B1 (en) 2008-12-24
DE60325502D1 (de) 2009-02-05
WO2004041268A1 (en) 2004-05-21
CA2502973A1 (en) 2004-05-21
EP1558242A1 (en) 2005-08-03
JP2006508186A (ja) 2006-03-09
ATE418333T1 (de) 2009-01-15
BR0316010A (pt) 2005-09-13
JP4764165B2 (ja) 2011-08-31
ES2318202T3 (es) 2009-05-01
AU2003276467A1 (en) 2004-06-07

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