MXPA04003761A - Lipidos cationicos anfofilos derivados del colesterol. - Google Patents

Lipidos cationicos anfofilos derivados del colesterol.

Info

Publication number
MXPA04003761A
MXPA04003761A MXPA04003761A MXPA04003761A MXPA04003761A MX PA04003761 A MXPA04003761 A MX PA04003761A MX PA04003761 A MXPA04003761 A MX PA04003761A MX PA04003761 A MXPA04003761 A MX PA04003761A MX PA04003761 A MXPA04003761 A MX PA04003761A
Authority
MX
Mexico
Prior art keywords
cholesterol
group
amphiphilic cationic
cationic lipids
lipids derived
Prior art date
Application number
MXPA04003761A
Other languages
English (en)
Inventor
Alonso Daniel
Original Assignee
Sterrenbeld Biotechnologie North America Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sterrenbeld Biotechnologie North America Inc filed Critical Sterrenbeld Biotechnologie North America Inc
Publication of MXPA04003761A publication Critical patent/MXPA04003761A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J9/00—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of more than two carbon atoms, e.g. cholane, cholestane, coprostane

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Steroid Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

Lipidos cationicos anfofilos derivados del colesterol poseyendo: 1) una entidad hidrofilica que incluye un grupo dimetilamino, 2) un grupo espaciador que incluye al menos 2 atomos de carbono enlazada a la entidad hidrofilica, 3) una union colectora que incluye un grupo ester carboxilico, carbamato y carbonato enlazada al grupo espaciador y 4) un grupo lipofilico derivado del colesterol enlazado a la union conectara.
MXPA04003761A 2001-10-22 2001-10-22 Lipidos cationicos anfofilos derivados del colesterol. MXPA04003761A (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/US2001/032399 WO2003035669A1 (en) 2001-10-22 2001-10-22 Amphiphilic cationic lipids derived from cholesterol

Publications (1)

Publication Number Publication Date
MXPA04003761A true MXPA04003761A (es) 2005-04-08

Family

ID=21742918

Family Applications (1)

Application Number Title Priority Date Filing Date
MXPA04003761A MXPA04003761A (es) 2001-10-22 2001-10-22 Lipidos cationicos anfofilos derivados del colesterol.

Country Status (2)

Country Link
MX (1) MXPA04003761A (es)
WO (1) WO2003035669A1 (es)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8329681B2 (en) * 2005-08-11 2012-12-11 University Of Massachusetts Methods and compositions for the efficient delivery of therapeutic agents to cells and animals
DE102007029471A1 (de) * 2007-06-20 2008-12-24 Novosom Ag Neue fakultativ kationische Sterole

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5283185A (en) * 1991-08-28 1994-02-01 University Of Tennessee Research Corporation Method for delivering nucleic acids into cells
US5935936A (en) * 1996-06-03 1999-08-10 Genzyme Corporation Compositions comprising cationic amphiphiles and co-lipids for intracellular delivery of therapeutic molecules

Also Published As

Publication number Publication date
WO2003035669A1 (en) 2003-05-01

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Legal Events

Date Code Title Description
FG Grant or registration