MXPA04002141A - Intermediarios para preparar conjugados inhibidores de la neuraminidasa. - Google Patents

Intermediarios para preparar conjugados inhibidores de la neuraminidasa.

Info

Publication number
MXPA04002141A
MXPA04002141A MXPA04002141A MXPA04002141A MXPA04002141A MX PA04002141 A MXPA04002141 A MX PA04002141A MX PA04002141 A MXPA04002141 A MX PA04002141A MX PA04002141 A MXPA04002141 A MX PA04002141A MX PA04002141 A MXPA04002141 A MX PA04002141A
Authority
MX
Mexico
Prior art keywords
intermediates
neuraminidase inhibitor
inhibitor conjugates
preparing
preparing neuraminidase
Prior art date
Application number
MXPA04002141A
Other languages
English (en)
Inventor
George Adam Inglis Graham
Original Assignee
Biota Scient Management
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Biota Scient Management filed Critical Biota Scient Management
Publication of MXPA04002141A publication Critical patent/MXPA04002141A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D407/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00
    • C07D407/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings
    • C07D407/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/16—Antivirals for RNA viruses for influenza or rhinoviruses
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D309/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings
    • C07D309/16—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D309/28—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Virology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pulmonology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pyrane Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)

Abstract

Compuestos de formula (I), metodos para su preparacion y su uso en la fabricacion de conjugados inhibidores de la neuraminidasa, en donde R representa un grupo protector de acido carboxilico; P1 y P2 pueden ser iguales o diferentes y se seleccionan a partir de grupos protectores de amina; P3 representa un grupo protector para 1, 2 dioles; y LG representa un grupo de salida.
MXPA04002141A 2001-09-07 2002-08-30 Intermediarios para preparar conjugados inhibidores de la neuraminidasa. MXPA04002141A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
AUPR757401 2001-09-07
PCT/AU2002/001187 WO2003022841A1 (en) 2001-09-07 2002-08-30 Intermediates for preparing neuraminidase inhibitor conjugates

Publications (1)

Publication Number Publication Date
MXPA04002141A true MXPA04002141A (es) 2004-07-23

Family

ID=3831510

Family Applications (1)

Application Number Title Priority Date Filing Date
MXPA04002141A MXPA04002141A (es) 2001-09-07 2002-08-30 Intermediarios para preparar conjugados inhibidores de la neuraminidasa.

Country Status (12)

Country Link
US (1) US7230114B2 (es)
EP (1) EP1423385B1 (es)
JP (1) JP4463553B2 (es)
AT (1) ATE399779T1 (es)
BR (1) BR0212261A (es)
CA (1) CA2456239C (es)
DE (1) DE60227386D1 (es)
DK (1) DK1423385T3 (es)
ES (1) ES2307776T3 (es)
MX (1) MXPA04002141A (es)
PT (1) PT1423385E (es)
WO (1) WO2003022841A1 (es)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104418876B (zh) * 2013-09-09 2019-05-17 中国科学院上海有机化学研究所 扎那米韦和拉那米韦的中间体及其合成方法
CN113461631B (zh) * 2021-06-29 2022-10-14 上海应用技术大学 一种1,3,4-恶二唑类神经氨酸酶抑制剂及其制备方法与应用

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9516276D0 (en) * 1995-08-08 1995-10-11 Biota Scient Management Chemical compounds
ATE238552T1 (de) 1996-03-01 2003-05-15 Biota Scient Management Verfahren zum nachweis von influenza-virus und dazu verwendbare verbindungen
DE69721553T2 (de) * 1996-08-13 2004-07-22 Sankyo Co., Ltd. Verbindungen der neuraminsaeure
AUPR001000A0 (en) * 2000-09-08 2000-10-05 Biota Scientific Management Pty Ltd Novel chemical compounds and their use

Also Published As

Publication number Publication date
CA2456239C (en) 2010-11-30
JP2005501921A (ja) 2005-01-20
WO2003022841A1 (en) 2003-03-20
DE60227386D1 (de) 2008-08-14
US20050032853A1 (en) 2005-02-10
EP1423385A4 (en) 2004-12-01
US7230114B2 (en) 2007-06-12
EP1423385B1 (en) 2008-07-02
BR0212261A (pt) 2004-10-19
CA2456239A1 (en) 2003-03-20
DK1423385T3 (da) 2008-11-03
EP1423385A1 (en) 2004-06-02
ATE399779T1 (de) 2008-07-15
ES2307776T3 (es) 2008-12-01
JP4463553B2 (ja) 2010-05-19
PT1423385E (pt) 2008-09-24

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Legal Events

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FG Grant or registration