MXPA02011938A - Adn que codifica para un receptor de histamina de mamifero del subtipo h4. - Google Patents

Adn que codifica para un receptor de histamina de mamifero del subtipo h4.

Info

Publication number
MXPA02011938A
MXPA02011938A MXPA02011938A MXPA02011938A MXPA02011938A MX PA02011938 A MXPA02011938 A MX PA02011938A MX PA02011938 A MXPA02011938 A MX PA02011938A MX PA02011938 A MXPA02011938 A MX PA02011938A MX PA02011938 A MXPA02011938 A MX PA02011938A
Authority
MX
Mexico
Prior art keywords
recombinant
dnas encoding
subtype
host cells
receptor
Prior art date
Application number
MXPA02011938A
Other languages
English (en)
Inventor
Changlu Liu
Original Assignee
Johnson & Johnson
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Johnson & Johnson filed Critical Johnson & Johnson
Publication of MXPA02011938A publication Critical patent/MXPA02011938A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/72—Receptors; Cell surface antigens; Cell surface determinants for hormones
    • C07K14/723—G protein coupled receptor, e.g. TSHR-thyrotropin-receptor, LH/hCG receptor, FSH receptor
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/10—Laxatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/08—Drugs for disorders of the urinary system of the prostate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/06—Antiarrhythmics

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Diabetes (AREA)
  • Endocrinology (AREA)
  • Pulmonology (AREA)
  • Immunology (AREA)
  • Zoology (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Cardiology (AREA)
  • Toxicology (AREA)
  • Cell Biology (AREA)
  • Pain & Pain Management (AREA)
  • Hematology (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Psychiatry (AREA)
  • Rheumatology (AREA)
  • Neurosurgery (AREA)
  • Obesity (AREA)
  • Urology & Nephrology (AREA)
  • Emergency Medicine (AREA)

Abstract

ADN que codifican los receptores de histamina H4 de mamifero han sido clonados y caracterizados; estas moleculas recombinantes son capaces de expresar proteina de receptor de histamina H4 biologicamente activa; los ADNc han sido expresados en celulas hospedero recombinantes que producen proteina recombinante activa; la farmacotogia de ligandos de histamina conocidos esta demostrada; la proteina recombinante se puede purificar a partir de las celulas hospedero recombinantes; ademas, las celulas hospedero recombinantes se utilizan para establecer metodos para identificar moduladores de la actividad del receptor, y se identifican los moduladores del receptor.
MXPA02011938A 2000-05-31 2001-02-22 Adn que codifica para un receptor de histamina de mamifero del subtipo h4. MXPA02011938A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US20826000P 2000-05-31 2000-05-31
PCT/US2001/005914 WO2001092485A1 (en) 2000-05-31 2001-02-22 DNAs ENCODING MAMMALIAN HISTAMINE RECEPTOR OF THE H4 SUBTYPE

Publications (1)

Publication Number Publication Date
MXPA02011938A true MXPA02011938A (es) 2004-09-06

Family

ID=22773916

Family Applications (1)

Application Number Title Priority Date Filing Date
MXPA02011938A MXPA02011938A (es) 2000-05-31 2001-02-22 Adn que codifica para un receptor de histamina de mamifero del subtipo h4.

Country Status (8)

Country Link
US (3) US7183078B2 (es)
EP (1) EP1294856A4 (es)
JP (1) JP2004516005A (es)
AU (2) AU4171301A (es)
CA (1) CA2410734A1 (es)
MX (1) MXPA02011938A (es)
NZ (1) NZ523157A (es)
WO (1) WO2001092485A1 (es)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1545596A4 (en) * 2002-09-06 2005-12-28 Janssen Pharmaceutica Nv USE OF HISTAMINE H4 RECEPTOR MODULATORS FOR THE TREATMENT OF ALLERGIES AND ASTHMA
WO2011017093A1 (en) 2009-08-07 2011-02-10 Danisco Us Inc. Alpha-amylase blend for starch processing and method of use thereof
EP3210505B1 (de) * 2016-02-23 2020-04-08 Eversys Holding SA Erhitzereinheit für eine vorrichtung zur erhitzung und/oder aufschäumung von milch
US20240150832A1 (en) * 2021-08-04 2024-05-09 Hangzhou Zheda Dixun Biological Gene Engineering Co., Ltd Reagent for detecting expression level of human histamine receptor hrh4 mrna, kit and detection method
CN113584154A (zh) * 2021-08-04 2021-11-02 杭州浙大迪迅生物基因工程有限公司 一种检测人组胺受体HRH4 mRNA表达水平的试剂、试剂盒和应用

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5194596A (en) 1989-07-27 1993-03-16 California Biotechnology Inc. Production of vascular endothelial cell growth factor
US5350836A (en) * 1989-10-12 1994-09-27 Ohio University Growth hormone antagonists
US5885824A (en) * 1990-12-24 1999-03-23 The Regents Of The University Of Michigan Recombinant genomic clone encoding the histamine H2 receptor, methods for production thereof, and protein produced therefrom
US5817480A (en) 1996-11-07 1998-10-06 Incyte Pharmaceuticals DNA encoding a histamine H2 receptor
US5882893A (en) 1997-12-04 1999-03-16 Millennium Pharmaceuticals, Inc. Nucleic acids encoding muscarinic receptors and uses therefor
US6136559A (en) * 1998-10-07 2000-10-24 Ortho Pharmaceutical Corporation DNA encoding as human histamine receptor of the H3 subtype
CA2348688A1 (en) * 1998-10-13 2000-04-20 Arena Pharmaceuticals, Inc. Non-endogenous, constitutively activated human g protein-coupled receptors
US6204017B1 (en) * 1999-10-07 2001-03-20 Schering Corporation Polynucleotide encoding a histamine receptor
WO2001085786A2 (en) 2000-05-05 2001-11-15 Wyeth Human histamine h4 receptor
US20020132755A1 (en) 2001-01-17 2002-09-19 Pfizer Inc. Histamine receptor antagonists

Also Published As

Publication number Publication date
CA2410734A1 (en) 2001-12-06
US7115395B2 (en) 2006-10-03
AU2001241713B2 (en) 2006-02-02
US20050074841A1 (en) 2005-04-07
AU2001241713C1 (en) 2006-11-30
EP1294856A4 (en) 2005-11-23
EP1294856A1 (en) 2003-03-26
WO2001092485A1 (en) 2001-12-06
US7202057B2 (en) 2007-04-10
AU4171301A (en) 2001-12-11
US20040248252A1 (en) 2004-12-09
US7183078B2 (en) 2007-02-27
US20050074770A1 (en) 2005-04-07
JP2004516005A (ja) 2004-06-03
NZ523157A (en) 2004-08-27

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