MXPA02011018A - Enzymatic treatment of whey proteins for the production of antihypertensive peptides, the resulting products and treatment of hypertension in mammals. - Google Patents

Enzymatic treatment of whey proteins for the production of antihypertensive peptides, the resulting products and treatment of hypertension in mammals.

Info

Publication number
MXPA02011018A
MXPA02011018A MXPA02011018A MXPA02011018A MXPA02011018A MX PA02011018 A MXPA02011018 A MX PA02011018A MX PA02011018 A MXPA02011018 A MX PA02011018A MX PA02011018 A MXPA02011018 A MX PA02011018A MX PA02011018 A MXPA02011018 A MX PA02011018A
Authority
MX
Mexico
Prior art keywords
treatment
hypertension
mammals
production
resulting products
Prior art date
Application number
MXPA02011018A
Other languages
Spanish (es)
Inventor
Anand Rao
Original Assignee
Davisco Internat Foods Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US09/567,283 external-priority patent/US6630320B1/en
Priority claimed from US09/702,068 external-priority patent/US6998259B1/en
Application filed by Davisco Internat Foods Inc filed Critical Davisco Internat Foods Inc
Publication of MXPA02011018A publication Critical patent/MXPA02011018A/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23JPROTEIN COMPOSITIONS FOR FOODSTUFFS; WORKING-UP PROTEINS FOR FOODSTUFFS; PHOSPHATIDE COMPOSITIONS FOR FOODSTUFFS
    • A23J3/00Working-up of proteins for foodstuffs
    • A23J3/30Working-up of proteins for foodstuffs by hydrolysis
    • A23J3/32Working-up of proteins for foodstuffs by hydrolysis using chemical agents
    • A23J3/34Working-up of proteins for foodstuffs by hydrolysis using chemical agents using enzymes
    • A23J3/341Working-up of proteins for foodstuffs by hydrolysis using chemical agents using enzymes of animal proteins
    • A23J3/343Working-up of proteins for foodstuffs by hydrolysis using chemical agents using enzymes of animal proteins of dairy proteins
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/55Protease inhibitors
    • A61K38/556Angiotensin converting enzyme inhibitors
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/12Antihypertensives
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P21/00Preparation of peptides or proteins
    • C12P21/06Preparation of peptides or proteins produced by the hydrolysis of a peptide bond, e.g. hydrolysate products

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Zoology (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biochemistry (AREA)
  • Wood Science & Technology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Immunology (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Molecular Biology (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Vascular Medicine (AREA)
  • Genetics & Genomics (AREA)
  • General Engineering & Computer Science (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Epidemiology (AREA)
  • Nutrition Science (AREA)
  • Food Science & Technology (AREA)
  • Polymers & Plastics (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Coloring Foods And Improving Nutritive Qualities (AREA)
  • Peptides Or Proteins (AREA)

Abstract

Enzymatic digests of whey protein concentrates were prepared using animal, bacterial and fungal proteases, and evaluated for antihypertensive activities. ACE inhibitory activity and antihypertension activity were obtained with a hydrolysate of whey protein isolate prepared with a porcine trypsin.
MXPA02011018A 2000-05-08 2001-05-08 Enzymatic treatment of whey proteins for the production of antihypertensive peptides, the resulting products and treatment of hypertension in mammals. MXPA02011018A (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US09/567,283 US6630320B1 (en) 2000-05-08 2000-05-08 Treatment of hypertension in mammals with hydrolyzed whey proteins
US09/702,068 US6998259B1 (en) 1999-05-20 2000-10-30 Enzymatic treatment of whey proteins for the production of antihypertensive peptides and the resulting products
PCT/US2001/014797 WO2001085984A1 (en) 2000-05-08 2001-05-08 Enzymatic treatment of whey proteins for the production of antihypertensive peptides, the resulting products and treatment of hypertension in mammals

Publications (1)

Publication Number Publication Date
MXPA02011018A true MXPA02011018A (en) 2004-08-19

Family

ID=27074429

Family Applications (1)

Application Number Title Priority Date Filing Date
MXPA02011018A MXPA02011018A (en) 2000-05-08 2001-05-08 Enzymatic treatment of whey proteins for the production of antihypertensive peptides, the resulting products and treatment of hypertension in mammals.

Country Status (7)

Country Link
EP (1) EP1287159A4 (en)
JP (1) JP2004519204A (en)
AU (1) AU2001259625A1 (en)
CA (1) CA2415688A1 (en)
MX (1) MXPA02011018A (en)
NZ (1) NZ523036A (en)
WO (1) WO2001085984A1 (en)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6919314B1 (en) 1998-06-17 2005-07-19 New Zealand Dairy Board Bioactive whey protein hydrolysate
JP2005538704A (en) 2002-07-01 2005-12-22 ユニリーバー・ナームローゼ・ベンノートシヤープ Satiety-inducing composition
US7718171B2 (en) 2003-04-07 2010-05-18 Chr. Hansen A/S Reducing heart rate in mammals using milk derived fermentation products produced using Lactobacillus helveticus
EP1466529A1 (en) * 2003-04-07 2004-10-13 Chr. Hansen A/S Composition with heart rate reducing properties
US20060216330A1 (en) * 2003-05-05 2006-09-28 Janssen Johannes G Peptides having an ace inhibiting effect
ES2253036B1 (en) 2003-07-31 2007-07-16 Consejo Sup. Investig. Cientificas BIOACTIVE PEPTIDES DERIVED FROM PROTEINS OF THE EGG CLEAR BY ENZYMATIC HYDROLYSIS.
RU2006125434A (en) * 2003-12-15 2008-01-27 Юнилевер Н.В. (Nl) PEPTIDES WITH ACE-INHIBITING ACTION
EP1685764A1 (en) 2005-01-27 2006-08-02 Globus Egg Sciences B.V. Anti-hypertensive functional food products
NL1026931C2 (en) * 2004-08-31 2006-03-01 Friesland Brands Bv ACE-inhibiting whey hydrolysates.
WO2006024673A1 (en) 2004-09-03 2006-03-09 Chr. Hansen A/S Fermented milk or vegetable proteins comprising receptor ligand and uses thereof
FR2876389B1 (en) * 2004-10-13 2007-05-25 Viridis Sa HYDROLYSATS OF WHITE PROTEINS FROM LUZERNE
ES2319475B1 (en) 2005-06-08 2010-02-16 Consejo Superior Investig. Cientificas BIOACTIVE PEPTIDES IDENTIFIED IN ENZYMATIC HYDROLYZES OF LACTEE CASEINS AND PROCEDURE OF OBTAINING.
DE102008032828A1 (en) 2008-07-02 2010-01-07 Technische Universität Dresden Tryptophan-containing peptides from alpha-lactalbumin with hypotensive and vasoprotective action for biofunctional foods
EA035522B1 (en) 2013-04-25 2020-06-29 Янссен Вэксинс Энд Превеншн Б.В. Stabilized soluble prefusion rsv f polypeptides
US10457708B2 (en) 2015-07-07 2019-10-29 Janssen Vaccines & Prevention B.V. Stabilized soluble pre-fusion RSV F polypeptides
EP3821906A1 (en) 2015-07-07 2021-05-19 Janssen Vaccines & Prevention B.V. Vaccine against rsv comprising modified f polypeptide
IL262109B2 (en) 2016-04-05 2023-04-01 Janssen Vaccines Prevention B V Vaccine against rsv
PE20190420A1 (en) 2016-04-05 2019-03-19 Janssen Vaccines And Prevention B V SOLUBLE AND STABILIZED RESPIRATORY SYNCITIAL VIRUS (RSV) PREFUSION PROTEINS F
MY194419A (en) 2016-05-30 2022-11-30 Janssen Vaccines & Prevention Bv Stabilized pre-fusion rsv f proteins
WO2018210871A1 (en) 2017-05-17 2018-11-22 Janssen Vaccines & Prevention B.V. Methods and compositions for inducing protective immunity against rsv infection
EP3624844A1 (en) 2017-05-17 2020-03-25 Janssen Vaccines & Prevention B.V. Methods and compositions for inducing protective immunity against rsv infection
MX2020002876A (en) 2017-09-15 2020-07-22 Janssen Vaccines & Prevention Bv Method for the safe induction of immunity against rsv.

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP3149199B2 (en) * 1991-03-12 2001-03-26 カルピス株式会社 Angiotensin converting enzyme inhibitory peptide
JP3091772B2 (en) * 1991-03-12 2000-09-25 カルピス株式会社 Angiotensin converting enzyme inhibiting peptide composition
US5744179A (en) * 1992-11-30 1998-04-28 Morinaga Milk Industry Co., Ltd. Low-phosphorus whey protein, manufacturing method thereof, low-phosphorus purified whey hydrolysate and manufacturing method thereof
JPH06345664A (en) * 1993-06-11 1994-12-20 Takako Tomita New composition for suppressing elevation of blood pressure
JPH1033115A (en) * 1996-07-24 1998-02-10 Nouchikusangiyou Shinko Jigyodan Whey beverage and its production
US5854029A (en) * 1996-08-02 1998-12-29 Calpis Co., Ltd. Method for preparing antihypertensive agent

Also Published As

Publication number Publication date
EP1287159A4 (en) 2005-02-09
EP1287159A1 (en) 2003-03-05
WO2001085984A1 (en) 2001-11-15
CA2415688A1 (en) 2001-11-15
NZ523036A (en) 2004-04-30
AU2001259625A1 (en) 2001-11-20
JP2004519204A (en) 2004-07-02

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