MX9807266A - - Google Patents
Info
- Publication number
- MX9807266A MX9807266A MX9807266A MX9807266A MX9807266A MX 9807266 A MX9807266 A MX 9807266A MX 9807266 A MX9807266 A MX 9807266A MX 9807266 A MX9807266 A MX 9807266A MX 9807266 A MX9807266 A MX 9807266A
- Authority
- MX
- Mexico
- Prior art keywords
- threo
- methylphenidate
- proceeds
- single enantiomer
- substantially single
- Prior art date
Links
- CILPHQCEVYJUDN-VWYCJHECSA-N 2-[(1s,2s,5r)-5-methyl-2-propan-2-ylcyclohexyl]oxyacetic acid Chemical compound CC(C)[C@@H]1CC[C@@H](C)C[C@@H]1OCC(O)=O CILPHQCEVYJUDN-VWYCJHECSA-N 0.000 abstract 1
- 229960001042 dexmethylphenidate Drugs 0.000 abstract 1
- DUGOZIWVEXMGBE-CHWSQXEVSA-N dexmethylphenidate Chemical compound C([C@@H]1[C@H](C(=O)OC)C=2C=CC=CC=2)CCCN1 DUGOZIWVEXMGBE-CHWSQXEVSA-N 0.000 abstract 1
- 238000004519 manufacturing process Methods 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/08—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
- C07D211/18—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D211/34—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
- A61K31/4458—Non condensed piperidines, e.g. piperocaine only substituted in position 2, e.g. methylphenidate
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D9/00—Crystallisation
- B01D9/0004—Crystallisation cooling by heat exchange
- B01D9/0013—Crystallisation cooling by heat exchange by indirect heat exchange
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Physics & Mathematics (AREA)
- Thermal Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Crystallography & Structural Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Hydrogenated Pyridines (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Electrophonic Musical Instruments (AREA)
- Read Only Memory (AREA)
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB9604943.2A GB9604943D0 (en) | 1996-03-08 | 1996-03-08 | Resolution |
| GB9604943.2 | 1996-03-08 | ||
| US1698696P | 1996-05-07 | 1996-05-07 | |
| US016986 | 1996-05-07 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| MX9807266A true MX9807266A (https=) | 1999-08-31 |
| MXPA98007266A MXPA98007266A (en) | 1999-10-14 |
| MX202728B MX202728B (https=) | 2001-06-29 |
Family
ID=
Also Published As
| Publication number | Publication date |
|---|---|
| CA2243542C (en) | 2003-02-18 |
| CA2243542A1 (en) | 1997-09-12 |
| JP4138005B2 (ja) | 2008-08-20 |
| ES2173422T3 (es) | 2002-10-16 |
| EP0885191B1 (en) | 2002-01-23 |
| ATE212336T1 (de) | 2002-02-15 |
| KR19990087441A (ko) | 1999-12-27 |
| PT885191E (pt) | 2002-06-28 |
| DK0885191T3 (da) | 2002-05-06 |
| AU2102497A (en) | 1997-09-22 |
| EP0885191A1 (en) | 1998-12-23 |
| WO1997032851A1 (en) | 1997-09-12 |
| MX202728B (https=) | 2001-06-29 |
| DE69710051D1 (de) | 2002-03-14 |
| AU700836B2 (en) | 1999-01-14 |
| JP2000506162A (ja) | 2000-05-23 |
| KR100459149B1 (ko) | 2005-06-10 |
| DE69710051T2 (de) | 2002-08-14 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FG | Grant or registration | ||
| MM | Annulment or lapse due to non-payment of fees |