MX9806628A - Novel human myeloid terminal differentiation response gene - Google Patents

Novel human myeloid terminal differentiation response gene

Info

Publication number
MX9806628A
MX9806628A MX9806628A MX9806628A MX9806628A MX 9806628 A MX9806628 A MX 9806628A MX 9806628 A MX9806628 A MX 9806628A MX 9806628 A MX9806628 A MX 9806628A MX 9806628 A MX9806628 A MX 9806628A
Authority
MX
Mexico
Prior art keywords
myd118
polypeptide
provides
novel human
terminal differentiation
Prior art date
Application number
MX9806628A
Other languages
Spanish (es)
Other versions
MXPA98006628A (en
Inventor
Benjamin Graeme Cocks
Janice Au-Young
Jeffrey J Seilhamer
Original Assignee
Incyte Pharma Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US08/602,208 external-priority patent/US5866332A/en
Application filed by Incyte Pharma Inc filed Critical Incyte Pharma Inc
Publication of MX9806628A publication Critical patent/MX9806628A/en
Publication of MXPA98006628A publication Critical patent/MXPA98006628A/en

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  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Saccharide Compounds (AREA)

Abstract

The present invention provides polynucleotide and amino acid sequences which encode and identify a novel human myeloid terminal differentiation response gene designated MYD118. The present invention also provides for MYD118 antisense molecules. The invention further provides genetically engineered expression vectors and host cells for the production of purified MYD118 polypeptide; antibodies, antagonists and inhibitors of MYD118 polypeptide; and pharmaceutical compositions and methods of treatment based on polynucleotide sequences encoding MYD118 polypeptide. The invention specifically provides for use of the MYD118 polynucleotide sequences as a diagnostic composition for the detection of myeloproliferative diseases and leukemias. The invention also relates to therapeutic methods and compositions based upon the nucleotide and amino acid sequences for MYD118. The invention further provides antibodies which specifically bind to MYD118.
MXPA/A/1998/006628A 1996-02-15 1998-08-14 Gene of response of differentiation terminal honey honey noved MXPA98006628A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/602,208 US5866332A (en) 1994-02-02 1996-02-15 Human myeloid terminal differentiation response gene
US08602208 1996-02-15

Publications (2)

Publication Number Publication Date
MX9806628A true MX9806628A (en) 1998-12-31
MXPA98006628A MXPA98006628A (en) 1999-02-01

Family

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Also Published As

Publication number Publication date
JP2000517163A (en) 2000-12-26
CA2246578A1 (en) 1997-08-21
AU1960797A (en) 1997-09-02
EP0894137A1 (en) 1999-02-03

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