MX9806628A - Novel human myeloid terminal differentiation response gene - Google Patents
Novel human myeloid terminal differentiation response geneInfo
- Publication number
- MX9806628A MX9806628A MX9806628A MX9806628A MX9806628A MX 9806628 A MX9806628 A MX 9806628A MX 9806628 A MX9806628 A MX 9806628A MX 9806628 A MX9806628 A MX 9806628A MX 9806628 A MX9806628 A MX 9806628A
- Authority
- MX
- Mexico
- Prior art keywords
- myd118
- polypeptide
- provides
- novel human
- terminal differentiation
- Prior art date
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- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Saccharide Compounds (AREA)
Abstract
The present invention provides polynucleotide and amino acid sequences which encode and identify a novel human myeloid terminal differentiation response gene designated MYD118. The present invention also provides for MYD118 antisense molecules. The invention further provides genetically engineered expression vectors and host cells for the production of purified MYD118 polypeptide; antibodies, antagonists and inhibitors of MYD118 polypeptide; and pharmaceutical compositions and methods of treatment based on polynucleotide sequences encoding MYD118 polypeptide. The invention specifically provides for use of the MYD118 polynucleotide sequences as a diagnostic composition for the detection of myeloproliferative diseases and leukemias. The invention also relates to therapeutic methods and compositions based upon the nucleotide and amino acid sequences for MYD118. The invention further provides antibodies which specifically bind to MYD118.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US08/602,208 US5866332A (en) | 1994-02-02 | 1996-02-15 | Human myeloid terminal differentiation response gene |
US08602208 | 1996-02-15 |
Publications (2)
Publication Number | Publication Date |
---|---|
MX9806628A true MX9806628A (en) | 1998-12-31 |
MXPA98006628A MXPA98006628A (en) | 1999-02-01 |
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Also Published As
Publication number | Publication date |
---|---|
JP2000517163A (en) | 2000-12-26 |
CA2246578A1 (en) | 1997-08-21 |
AU1960797A (en) | 1997-09-02 |
EP0894137A1 (en) | 1999-02-03 |
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